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Aliases for FAM9A Gene

Aliases for FAM9A Gene

  • Family With Sequence Similarity 9 Member A 2 3 5
  • Family With Sequence Similarity 9, Member A 2 3
  • Testis Expressed 39A 2 3
  • TEX39A 3

External Ids for FAM9A Gene

Previous GeneCards Identifiers for FAM9A Gene

  • GC0XU990384
  • GC0XM008105
  • GC0XM008170
  • GC0XM008568
  • GC0XM008718
  • GC0XM006586

Summaries for FAM9A Gene

Entrez Gene Summary for FAM9A Gene

  • This gene is a member of a gene family which arose through duplication on the X chromosome. The encoded protein may be a nuclear protein that is localized to the nucleolus, and has some similarity to a synaptonemal complex protein. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

GeneCards Summary for FAM9A Gene

FAM9A (Family With Sequence Similarity 9 Member A) is a Protein Coding gene. Diseases associated with FAM9A include Uterine Benign Neoplasm. An important paralog of this gene is FAM9C.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM9A Gene

Genomics for FAM9A Gene

Regulatory Elements for FAM9A Gene

Enhancers for FAM9A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM9A on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the FAM9A gene promoter:

Genomic Location for FAM9A Gene

8,790,774 bp from pter
8,801,383 bp from pter
10,610 bases
Minus strand

Genomic View for FAM9A Gene

Genes around FAM9A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM9A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM9A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM9A Gene

Proteins for FAM9A Gene

  • Protein details for FAM9A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM9A
    Protein Accession:
    Secondary Accessions:
    • B7ZLH5
    • Q2M2D1

    Protein attributes for FAM9A Gene

    332 amino acids
    Molecular mass:
    37339 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM9A Gene

Proteomics data for FAM9A Gene at MOPED

Post-translational modifications for FAM9A Gene

No Post-translational modifications

Other Protein References for FAM9A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM9A Gene

Domains & Families for FAM9A Gene

Protein Domains for FAM9A Gene


Suggested Antigen Peptide Sequences for FAM9A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM9 family.
  • Belongs to the FAM9 family.
genes like me logo Genes that share domains with FAM9A: view

No data available for Gene Families for FAM9A Gene

Function for FAM9A Gene

genes like me logo Genes that share phenotypes with FAM9A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM9A Gene

Localization for FAM9A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM9A Gene

Nucleus, nucleolus.

Subcellular locations from

Jensen Localization Image for FAM9A Gene COMPARTMENTS Subcellular localization image for FAM9A gene
Compartment Confidence
nucleus 4
cytosol 2

No data available for Gene Ontology (GO) - Cellular Components for FAM9A Gene

Pathways & Interactions for FAM9A Gene

SuperPathways for FAM9A Gene

No Data Available

Interacting Proteins for FAM9A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000370391 Q8IZU1-FAM9A_HUMAN for FAM9A Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for FAM9A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM9A Gene

Drugs & Compounds for FAM9A Gene

No Compound Related Data Available

Transcripts for FAM9A Gene

mRNA/cDNA for FAM9A Gene

(3) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM9A Gene

Family with sequence similarity 9, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM9A Gene

No ASD Table

Relevant External Links for FAM9A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM9A Gene

mRNA expression in normal human tissues for FAM9A Gene

mRNA differential expression in normal tissues according to GTEx for FAM9A Gene

This gene is overexpressed in Testis (x43.5) and Liver (x4.6).

Protein differential expression in normal tissues from HIPED for FAM9A Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM9A Gene

SOURCE GeneReport for Unigene cluster for FAM9A Gene Hs.382062

mRNA Expression by UniProt/SwissProt for FAM9A Gene

Tissue specificity: Expressed exclusively in testis.
genes like me logo Genes that share expression patterns with FAM9A: view

Protein tissue co-expression partners for FAM9A Gene

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for FAM9A Gene

Orthologs for FAM9A Gene

Evolution for FAM9A Gene

Gene Tree for FAM9A (if available)
Gene Tree for FAM9A (if available)

No data available for Orthologs for FAM9A Gene

Paralogs for FAM9A Gene

Paralogs for FAM9A Gene

(1) SIMAP similar genes for FAM9A Gene using alignment to 1 proteins: Pseudogenes for FAM9A Gene

genes like me logo Genes that share paralogs with FAM9A: view

Variants for FAM9A Gene

Sequence variations from dbSNP and Humsavar for FAM9A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs747795091 -- 8,796,668(+) AAAGC(A/G)TTACA intron-variant
rs747848233 -- 8,796,232(+) ATGAT(A/G)TAAAT intron-variant
rs747911456 -- 8,803,068(+) TTTTT(C/T)TTTGC upstream-variant-2KB
rs748449822 -- 8,798,231(+) AATGC(A/C)ATGTT intron-variant
rs748475047 -- 8,795,154(+) CTCCT(C/T)CTTCT reference, missense

Structural Variations from Database of Genomic Variants (DGV) for FAM9A Gene

Variant ID Type Subtype PubMed ID
esv2752339 CNV Gain 17911159

Variation tolerance for FAM9A Gene

Residual Variation Intolerance Score: 80.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.50; 55.32% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM9A Gene

Disorders for FAM9A Gene

MalaCards: The human disease database

(1) MalaCards diseases for FAM9A Gene - From: DISEASES

Disorder Aliases PubMed IDs
uterine benign neoplasm
- elite association - COSMIC cancer census association via MalaCards
Search FAM9A in MalaCards View complete list of genes associated with diseases

Relevant External Links for FAM9A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM9A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FAM9A Gene

Publications for FAM9A Gene

  1. A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed exclusively in testis: implications for recombinations in this region. (PMID: 12213195) Martinez-Garay I. … Kutsche K. (Genomics 2002) 3 4 23 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease. (PMID: 24705354) Butland S.L. … Hayden M.R. (Hum. Mol. Genet. 2014) 3
  4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for FAM9A Gene

Sources for FAM9A Gene