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Aliases for FAM98C Gene

Aliases for FAM98C Gene

  • Family With Sequence Similarity 98, Member C 2 3

External Ids for FAM98C Gene

Previous GeneCards Identifiers for FAM98C Gene

  • GC19P043586
  • GC19P038893
  • GC19P035341

Summaries for FAM98C Gene

GeneCards Summary for FAM98C Gene

FAM98C (Family With Sequence Similarity 98, Member C) is a Protein Coding gene. An important paralog of this gene is FAM98B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM98C Gene

Genomics for FAM98C Gene

Regulatory Elements for FAM98C Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM98C Gene

38,403,135 bp from pter
38,409,088 bp from pter
5,954 bases
Plus strand

Genomic View for FAM98C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM98C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM98C Gene

Proteins for FAM98C Gene

  • Protein details for FAM98C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM98C
    Protein Accession:
    Secondary Accessions:
    • A6NMW3
    • Q66K45

    Protein attributes for FAM98C Gene

    349 amino acids
    Molecular mass:
    37329 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM98C Gene


neXtProt entry for FAM98C Gene

Proteomics data for FAM98C Gene at MOPED

Post-translational modifications for FAM98C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM98C Gene

No data available for DME Specific Peptides for FAM98C Gene

Domains for FAM98C Gene

Protein Domains for FAM98C Gene


Suggested Antigen Peptide Sequences for FAM98C Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM98 family.
  • Belongs to the FAM98 family.
genes like me logo Genes that share domains with FAM98C: view

No data available for Gene Families for FAM98C Gene

Function for FAM98C Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM98C

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM98C Gene

Localization for FAM98C Gene

Subcellular locations from

Jensen Localization Image for FAM98C Gene COMPARTMENTS Subcellular localization image for FAM98C gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM98C Gene

Pathways for FAM98C Gene

SuperPathways for FAM98C Gene

No Data Available

Interacting Proteins for FAM98C Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000252530 for FAM98C Gene via STRING

Gene Ontology (GO) - Biological Process for FAM98C Gene


No data available for Pathways by source for FAM98C Gene

Transcripts for FAM98C Gene

Unigene Clusters for FAM98C Gene

Family with sequence similarity 98, member C:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM98C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM98C Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10
SP1: - - - - -
SP2: - -
SP3: - -
SP4: - - - -

Relevant External Links for FAM98C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM98C Gene

mRNA expression in normal human tissues for FAM98C Gene

Protein differential expression in normal tissues for FAM98C Gene

This gene is overexpressed in Peripheral blood mononuclear cells (11.5), Breast (9.8), and Testis (6.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM98C Gene

SOURCE GeneReport for Unigene cluster for FAM98C Gene Hs.355162

genes like me logo Genes that share expressions with FAM98C: view

Expression partners for FAM98C Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM98C Gene

Orthologs for FAM98C Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM98C Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM98C 35
  • 85.79 (n)
  • 82.28 (a)
FAM98C 36
  • 79 (a)
(Canis familiaris)
Mammalia FAM98C 35
  • 85.39 (n)
  • 81.38 (a)
FAM98C 36
  • 68 (a)
(Mus musculus)
Mammalia Fam98c 35
  • 78.98 (n)
  • 75.08 (a)
Fam98c 16
Fam98c 36
  • 72 (a)
(Pan troglodytes)
Mammalia FAM98C 35
  • 99.43 (n)
  • 99.71 (a)
FAM98C 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fam98c 35
  • 78.48 (n)
  • 74.77 (a)
(Monodelphis domestica)
Mammalia FAM98C 36
  • 68 (a)
(Anolis carolinensis)
Reptilia FAM98C 36
  • 37 (a)
(Danio rerio)
Actinopterygii FAM98C 36
  • 25 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5913 36
  • 20 (a)
(Caenorhabditis elegans)
Secernentea tag-322 36
  • 20 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 29 (a)
Species with no ortholog for FAM98C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for FAM98C Gene

Gene Tree for FAM98C (if available)
Gene Tree for FAM98C (if available)

Paralogs for FAM98C Gene

Paralogs for FAM98C Gene

(2) SIMAP similar genes for FAM98C Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with FAM98C: view

Variants for FAM98C Gene

Sequence variations from dbSNP and Humsavar for FAM98C Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3745957 -- 38,403,216(+) GCTCT(C/G)GGGTA synonymous-codon, reference
rs3745958 -- 38,403,284(+) GGACG(A/G)AAAGG intron-variant
rs3745959 -- 38,403,295(+) GATTC(C/T)CAGTG intron-variant
rs3745960 -- 38,403,310(+) CCCCG(A/C)CCCCT intron-variant
rs3745961 -- 38,403,462(+) CGGGC(A/G)CGGAG missense, reference

Structural Variations from Database of Genomic Variants (DGV) for FAM98C Gene

Variant ID Type Subtype PubMed ID
nsv833822 CNV Loss 17160897
nsv911658 CNV Loss 21882294
nsv470140 CNV Gain 18288195
nsv911659 CNV Loss 21882294
nsv911660 CNV Gain 21882294
nsv833823 CNV Loss 17160897
dgv3857n71 CNV Loss 21882294
dgv3858n71 CNV Loss 21882294

Relevant External Links for FAM98C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM98C Gene

Disorders for FAM98C Gene

No disorders were found for FAM98C Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM98C Gene

Publications for FAM98C Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PMID: 21139048) Danielsen J.M. … Nielsen M.L. (Mol. Cell Proteomics 2011) 3
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for FAM98C Gene

Sources for FAM98C Gene

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