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Aliases for FAM98A Gene

Aliases for FAM98A Gene

  • Family With Sequence Similarity 98, Member A 2 3

External Ids for FAM98A Gene

Summaries for FAM98A Gene

GeneCards Summary for FAM98A Gene

FAM98A (Family With Sequence Similarity 98, Member A) is a Protein Coding gene. An important paralog of this gene is FAM98C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM98A Gene

Genomics for FAM98A Gene

Genomic Location for FAM98A Gene

Start:
33,583,658 bp from pter
End:
33,599,382 bp from pter
Size:
15,725 bases
Orientation:
Minus strand

Genomic View for FAM98A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM98A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM98A Gene

Regulatory Elements for FAM98A Gene

Proteins for FAM98A Gene

  • Protein details for FAM98A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NCA5-FA98A_HUMAN
    Recommended name:
    Protein FAM98A
    Protein Accession:
    Q8NCA5
    Secondary Accessions:
    • B2RNA2
    • Q9Y3Y6

    Protein attributes for FAM98A Gene

    Size:
    519 amino acids
    Molecular mass:
    55401 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM98A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM98A Gene

Proteomics data for FAM98A Gene at MOPED

Post-translational modifications for FAM98A Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys325

Other Protein References for FAM98A Gene

No data available for DME Specific Peptides for FAM98A Gene

Domains for FAM98A Gene

Protein Domains for FAM98A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

FA98A_HUMAN
Family:
  • Belongs to the FAM98 family.:
    • Q8NCA5
genes like me logo Genes that share domains with FAM98A: view

No data available for Gene Families for FAM98A Gene

Function for FAM98A Gene

Gene Ontology (GO) - Molecular Function for FAM98A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with FAM98A: view

Phenotypes for FAM98A Gene

GenomeRNAi human phenotypes for FAM98A:
genes like me logo Genes that share phenotypes with FAM98A: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM98A Gene

Localization for FAM98A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM98A Gene COMPARTMENTS Subcellular localization image for FAM98A gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FAM98A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0072669 tRNA-splicing ligase complex IBA --
genes like me logo Genes that share ontologies with FAM98A: view

Pathways for FAM98A Gene

SuperPathways for FAM98A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM98A Gene

None

No data available for Pathways by source for FAM98A Gene

Transcripts for FAM98A Gene

Unigene Clusters for FAM98A Gene

Family with sequence similarity 98, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM98A Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
SP1: - - -
SP2: - -
SP3:
SP4:

Relevant External Links for FAM98A Gene

GeneLoc Exon Structure for
FAM98A
ECgene alternative splicing isoforms for
FAM98A

Expression for FAM98A Gene

mRNA expression in normal human tissues for FAM98A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM98A Gene

SOURCE GeneReport for Unigene cluster for FAM98A Gene Hs.468140

genes like me logo Genes that share expressions with FAM98A: view

Orthologs for FAM98A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM98A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM98A 36
  • 99.68 (n)
  • 99.42 (a)
FAM98A 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM98A 36
  • 92.51 (n)
  • 96.51 (a)
FAM98A 37
  • 97 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM98A 36
  • 94.97 (n)
  • 97.68 (a)
FAM98A 37
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam98a 36
  • 90.36 (n)
  • 93.59 (a)
Fam98a 16
Fam98a 37
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM98A 37
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM98A 37
  • 94 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam98a 36
  • 91.07 (n)
  • 93.79 (a)
chicken
(Gallus gallus)
Aves FAM98A 36
  • 72.5 (n)
  • 71.67 (a)
FAM98A 37
  • 84 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM98A 37
  • 84 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.2395 36
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100488558 36
  • 71.12 (n)
  • 74.61 (a)
zebrafish
(Danio rerio)
Actinopterygii fam98a 37
  • 67 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011248 36
  • 48.07 (n)
  • 44.88 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5913 36
  • 46.6 (n)
  • 37.93 (a)
CG5913 37
  • 34 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea tag-322 37
  • 27 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 46 (a)
OneToMany
Species with no ortholog for FAM98A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM98A Gene

ENSEMBL:
Gene Tree for FAM98A (if available)
TreeFam:
Gene Tree for FAM98A (if available)

Paralogs for FAM98A Gene

Paralogs for FAM98A Gene

Selected SIMAP similar genes for FAM98A Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with FAM98A: view

Variants for FAM98A Gene

Sequence variations from dbSNP and Humsavar for FAM98A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs3023 -- 33,592,814(+) CTTCC(C/T)AGCAT intron-variant
rs935625 -- 33,586,449(+) AAATC(C/G)CTATG intron-variant
rs1375198 -- 33,591,518(+) AAAAA(C/T)TCATT intron-variant
rs1375199 -- 33,596,331(+) GTTAG(C/G)TTAAT intron-variant
rs1448559 -- 33,591,739(+) TCCTA(A/G)TATAC intron-variant

Relevant External Links for FAM98A Gene

HapMap Linkage Disequilibrium report
FAM98A

No data available for Structural Variations from Database of Genomic Variants (DGV) for FAM98A Gene

Disorders for FAM98A Gene

Relevant External Links for FAM98A

Genetic Association Database (GAD)
FAM98A
genes like me logo Genes that share disorders with FAM98A: view

No data available for UniProtKB/Swiss-Prot for FAM98A Gene

Publications for FAM98A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. A divergent calponin homology (NN-CH) domain defines a novel family: implications for evolution of ciliary IFT complex B proteins. (PMID: 24257188) Schou K.B. … Pedersen L.B. (Bioinformatics 2014) 2 3
  3. Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress. (PMID: 24797263) Tong J. … Moran M.F. (Mol. Cell Proteomics 2014) 3
  4. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3
  5. Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways. (PMID: 25192599) Wang T. … Xu J. (Neurobiol. Aging 2015) 3

Products for FAM98A Gene

Sources for FAM98A Gene

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