Aliases for FAM92B Gene
Aliases for FAM92B Gene
External Ids for FAM92B Gene
- HGNC: 24781
- Entrez Gene: 339145
- Ensembl: ENSG00000153789
- OMIM: 617274
- UniProtKB: Q6ZTR7
Previous GeneCards Identifiers for FAM92B Gene
- GC16M083690
- GC16M085131
- GC16M070884
Summaries for FAM92B Gene
GeneCards Summary for FAM92B Gene
FAM92B (Family With Sequence Similarity 92 Member B) is a Protein Coding gene. An important paralog of this gene is FAM92A.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM92B Gene
Genomics for FAM92B Gene
Regulatory Elements for FAM92B Gene
Enhancers for FAM92B Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM92B on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM92B gene promoter:
Regulatory Element Products
Genomic Location for FAM92B Gene
- Chromosome:
- 16
- Start:
- 85,098,352 bp from pter
- End:
- 85,112,508 bp from pter
- Size:
- 14,157 bases
- Orientation:
- Minus strand
Genomic View for FAM92B Gene
Genes around FAM92B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 16q24.1 by Ensembl
- 16q24.1 by Entrez Gene
- 16q24.1 by HGNC
FAM92B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM92B Gene
Proteins for FAM92B Gene
-
Protein details for FAM92B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6ZTR7-FA92B_HUMAN
- Recommended name:
- Protein FAM92B
- Protein Accession:
- Q6ZTR7
Protein attributes for FAM92B Gene
- Size:
- 304 amino acids
- Molecular mass:
- 34785 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM92B Gene
Post-translational modifications for FAM92B Gene
Other Protein References for FAM92B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FAM92B
- Novus Biologicals Antibodies for FAM92B
- Invitrogen Antibodies for FAM92B
- GeneTex FAM92B antibody for FAM92B
Protein Products
-
OriGene Purified Proteins for FAM92B
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM92B
- Origene Custom Protein Services for FAM92B
- Search GeneTex for Proteins for FAM92B
Assay Products
No data available for DME Specific Peptides for FAM92B Gene
Domains & Families for FAM92B Gene
Protein Domains for FAM92B Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM92B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6ZTR7- Family:
-
- Belongs to the FAM92 family.
No data available for Gene Families for FAM92B Gene
Function for FAM92B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 27528616 |
Phenotypes for FAM92B Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM92B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92B gene
- Search ViGene Biosciences for FAM92B
CRISPR Products
-
OriGene CRISPR knockouts for FAM92B
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM92B
- GenScript: Design CRISPR guide RNA sequences for FAM92B
miRNA Products
- Search ViGene Biosciences for FAM92B
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM92B
- Browse OriGene Inhibitory RNA Products For FAM92B
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92B gene
Clone Products
-
OriGene ORF clones in human for FAM92B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM92B
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM92B gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM92B gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92B gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM92B Gene
Localization for FAM92B Gene
| Compartment | Confidence |
|---|---|
| cytoskeleton | 3 |
| nucleus | 2 |
| cytosol | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005814 | centriole | IEA | -- |
| GO:0036064 | ciliary basal body | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM92B Gene
Pathways & Interactions for FAM92B Gene
No Data Available
Interacting Proteins for FAM92B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0030030 | cell projection organization | IEA | -- |
No data available for Pathways by source and SIGNOR curated interactions for FAM92B Gene
Transcripts for FAM92B Gene
mRNA/cDNA for FAM92B Gene
- (4) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (9) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM92B Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM92B
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM92B
- GenScript: Design CRISPR guide RNA sequences for FAM92B
miRNA Products
- Search ViGene Biosciences for FAM92B
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM92B
- Browse OriGene Inhibitory RNA Products For FAM92B
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92B gene
Clone Products
-
OriGene ORF clones in human for FAM92B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM92B Gene
mRNA differential expression in normal tissues according to GTEx for FAM92B Gene
This gene is overexpressed in Pituitary (x12.9), Fallopian Tube (x8.1), Brain - Hypothalamus (x5.8), Lung (x4.8), and Cervix - Endocervix (x4.5).
This gene is overexpressed in Frontal cortex (18.3), Bone marrow mesenchymal stem cell (9.5), and Urinary Bladder (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM92B Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM92B Gene:
FAM92BSOURCE GeneReport for Unigene cluster for FAM92B Gene:
Hs.125713Evidence on tissue expression from TISSUES for FAM92B Gene
- Lung(4.2)
- Heart(4.1)
Primer Products
-
OriGene qPCR primer pairs for FAM92B
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM92B Gene
Orthologs for FAM92B Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM92B 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam92b 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM92B 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam92b 34 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM92B 34 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAM92B 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM92B 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam92b 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.12567 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6405 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11121 35 |
|
OneToMany |
- Species where no ortholog for FAM92B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM92B Gene
(1) SIMAP similar genes for FAM92B Gene using alignment to 2 proteins:
Variants for FAM92B Gene
| SNP ID | Clin | Chr 16 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000065261 | -- | 85,108,191(+) | AGCCG(C/T)GTGTC | intron-variant | |
| rs1000119533 | -- | 85,109,989(+) | GCTTC(C/T)TGGGT | intron-variant | |
| rs1000291687 | -- | 85,108,204(+) | GAGCT(C/G)TGCGG | intron-variant | |
| rs1000423872 | -- | 85,110,120(+) | ACACA(-/C)CCATT | intron-variant | |
| rs1000454778 | -- | 85,110,773(+) | GATCT(C/T)GGCTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3059n100 | CNV | gain | 25217958 |
| nsv1066002 | CNV | loss | 25217958 |
| nsv1066260 | CNV | gain | 25217958 |
| nsv483044 | CNV | gain | 15286789 |
| nsv573474 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
79.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.65;
56.88% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM92B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM92B
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM92B Gene
Disorders for FAM92B Gene
Relevant External Links for FAM92B
No disorders were found for FAM92B Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM92B Gene
Publications for FAM92B Gene
- BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis. (PMID: 27528616) Li F.Q. … Takemaru K.I. (Mol. Cell. Biol. 2016) 2 3 64
- rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. (PMID: 19262523) Glas J. … Brand S. (Am. J. Gastroenterol. 2009) 3 46 64
- Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort. (PMID: 18580884) Roberts R.L. … Merriman T.R. (Genes Immun. 2008) 3 46 64
- NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in Canadian children and young adults. (PMID: 21472827) Amre D.K. … Levy E. (Inflamm. Bowel Dis. 2012) 3 64
- A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. (PMID: 17068223) Duerr R.H. … Cho J.H. (Science 2006) 46 64
Products for FAM92B Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
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- Browse Immunoprecipitation Assays
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- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for FAM92B
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FAM92B
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM92B
- Origene Custom Protein Services for FAM92B
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM92B
- Browse OriGene Inhibitory RNA Products For FAM92B
- OriGene qPCR primer pairs for FAM92B
- OriGene CRISPR knockouts for FAM92B
- OriGene ORF clones in human for FAM92B
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FAM92B
- GenScript: Next-day shipping cDNA ORF clone for FAM92B in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM92B
- GenScript Custom Assay Services for FAM92B
- GenScript Custom overexpressing Cell Line Services for FAM92B
- GenScript: Design CRISPR guide RNA sequences for FAM92B
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM92B
- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FAM92B
- Novus Biologicals proteins and lysates for FAM92B
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for FAM92B gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM92B gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM92B gene
- Search ViGene Biosciences for FAM92B
- Horizon Cell Lines for FAM92B
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM92B
- VectorBuilder custom plasmid, inducible vectors for FAM92B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM92B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM92B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer