FAM92B Gene
protein-coding GIFtS: 41
GCID: GC16M085131 (predicted)
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family with sequence similarity 92, member B
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Aliases
for FAM92B gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 92, Member B1 2 | | FLJ442991 | | Protein FAM92B2 |
Export aliases for FAM92B gene to outside databasesPrevious GC identifers: GC16M083690 GC16M070884 |
Summaries
for FAM92B gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM92B gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM92B gene promoter:
AhR LHX3b/Lhx3b NF-1 Brachyury HTF Roaz Egr-2 AREB6 FOXO4 LHX3a/Lhx3a
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM92B
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM92B |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24.1 Ensembl cytogenetic band: 16q24.1 HGNC cytogenetic band: 16q24.1FAM92B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M085131: view genomic region
(about GC identifiers)
Start:
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85,131,965 bp from pter |
End:
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85,146,114 bp from pter |
Size:
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14,150 bases |
Orientation:
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minus strand |
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Proteins
for FAM92B gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FA92B_HUMAN, Q6ZTR7 (See
protein sequence)Recommended Name: Protein FAM92B Size: 304 amino acids; 34785 DaExplore the universe of human proteins at neXtProt for FAM92B: NX_Q6ZTR7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6ZTR7
FAM92B Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_940893.1
ENSEMBL proteins: ENSP00000443411
Human Recombinant Protein Products:
FAM92B Antibody Products:
Assay Products for FAM92B: |
Protein
Domains /
Families
for FAM92B gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM92B for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6ZTR7ProtoNet protein and cluster: Q6ZTR7 UniProtKB/Swiss-Prot: FA92B_HUMAN, Q6ZTR7Similarity: Belongs to the FAM92 family |
Function
for FAM92B gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM92B (NM_198491) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM92B | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM92B |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM92B |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0019904 | protein domain specific binding |
IEA | -- |
FAM92B for ontologies About GeneDecksing
|
Pathways & Interactions
for FAM92B gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM92B
|
Drugs & Compounds
for FAM92B gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM92B
Search CenterWatch for drugs/clinical trials and news about FAM92B / FA92B
|
Transcripts
for FAM92B gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM92B gene: NM_198491.1 Unigene Cluster for FAM92B: Family with sequence similarity 92, member B Hs.125713 [show with all ESTs]Unigene Representative Sequence: AK1262841 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000539556(uc021tlz.1 uc021tma.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92B (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92B
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM92B (NM_198491) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM92B | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM92B |
Additional cDNA sequence: AK126284.1 BC093665.1 BC111944.1 3 DOTS entries: DT.99975300 DT.300311 DT.120691278 9 AceView cDNA sequences: CA438550 BU685247 AI672213 AA885104 NM_198491 BU680724 AK126284 AI935262 AW009602
GeneLoc Exon Structure
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Expression
for FAM92B gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM92B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGAGGCCC
About this image
SOURCE GeneReport for Unigene cluster: Hs.125713
SABiosciences Custom PCR Arrays for FAM92B
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM92B
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM92B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM92B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM92B | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM92B |
Orthologs
for FAM92B gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for FAM92B gene from 2/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.125672 |
Xenopus laevis transcribed sequences |
75.14(n) |
|
BJ070674.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG64056 |
-- |
16(a) |
1 → many |
2L(12424904-12426440) |
ENSEMBL Gene Tree for FAM92B (if available)
TreeFam Gene Tree for FAM92B (if available) |
Paralogs
for FAM92B gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM92B gene
- FAM92A12
1 SIMAP similar gene for FAM92B using alignment to 2 protein entries: FA92B_HUMAN (see all proteins):FAM92A1
FAM92B for paralogs About GeneDecksing
|
Genomic Variants
for FAM92B gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM92B (85131965 - 85146114 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM92B: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM92B |
|
Disorders
/ Diseases
for FAM92B gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM92B for disorders About GeneDecksing
1  disease for FAM92B: About MalaCardscrohn's disease
1 disease from the University of Copenhagen DISEASES database for FAM92B:Crohn's disease Human Genome Epidemiology (HuGE) Navigator: FAM92B (3 documents)
Export disorders for FAM92B gene to outside databases
|
Publications
for FAM92B gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM92B gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM92B) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- NELL1, NCF4, and FAM92B genes are not major susceptibi lity genes for Crohn's disease in Canadian children and young adults. (PubMed id 21472827)1 Amre D.K....Levy E. (2012)
- rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. (PubMed id 19262523)1 Glas J....Brand S. (2009)
- Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort. (PubMed id 18580884)1 Roberts R.L....Merriman T.R. (2008)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
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External Searches for FAM92B gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM92B gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM92B gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM92B gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM92B | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM92B gene:
Search GeneIP for patents involving FAM92B
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM92B gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM92B | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM92B | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM92B | | | OriGene Protein Over-expression Lysate for FAM92B | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM92B | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92B | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92B | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM92B | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM92B | | OriGene Custom Protein Services for FAM92B | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM92B | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM92B | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM92B | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM92B | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM92B | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM92B |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM92B |
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 | | | FAM92B Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM92B |
|  |  |  | | | | ThermoFisher Antibodies for FAM92B |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM92B |
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