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Aliases for FAM92B Gene

Aliases for FAM92B Gene

  • Family With Sequence Similarity 92, Member B 2 3

External Ids for FAM92B Gene

Previous GeneCards Identifiers for FAM92B Gene

  • GC16M083690
  • GC16M085131
  • GC16M070884

Summaries for FAM92B Gene

GeneCards Summary for FAM92B Gene

FAM92B (Family With Sequence Similarity 92, Member B) is a Protein Coding gene. An important paralog of this gene is FAM92A1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM92B Gene

Genomics for FAM92B Gene

Regulatory Elements for FAM92B Gene

Genomic Location for FAM92B Gene

85,098,352 bp from pter
85,112,508 bp from pter
14,157 bases
Minus strand

Genomic View for FAM92B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM92B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM92B Gene

Proteins for FAM92B Gene

  • Protein details for FAM92B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM92B
    Protein Accession:

    Protein attributes for FAM92B Gene

    304 amino acids
    Molecular mass:
    34785 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM92B Gene

Proteomics data for FAM92B Gene at MOPED

Post-translational modifications for FAM92B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM92B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM92B Gene

Domains & Families for FAM92B Gene

Protein Domains for FAM92B Gene


Suggested Antigen Peptide Sequences for FAM92B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM92 family.
  • Belongs to the FAM92 family.
genes like me logo Genes that share domains with FAM92B: view

No data available for Gene Families for FAM92B Gene

Function for FAM92B Gene

genes like me logo Genes that share phenotypes with FAM92B: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM92B Gene

Localization for FAM92B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM92B Gene

Pathways & Interactions for FAM92B Gene

SuperPathways for FAM92B Gene

No Data Available

Interacting Proteins for FAM92B Gene

Gene Ontology (GO) - Biological Process for FAM92B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM92B Gene

Drugs & Compounds for FAM92B Gene

No Compound Related Data Available

Transcripts for FAM92B Gene

mRNA/cDNA for FAM92B Gene

(3) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(9) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM92B Gene

Family with sequence similarity 92, member B:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM92B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM92B Gene

No ASD Table

Relevant External Links for FAM92B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM92B Gene

mRNA expression in normal human tissues for FAM92B Gene

mRNA differential expression in normal tissues according to GTEx for FAM92B Gene

This gene is overexpressed in Pituitary (x12.9), Fallopian Tube (x8.1), Brain - Hypothalamus (x5.8), Lung (x4.8), and Cervix - Endocervix (x4.5).

Protein differential expression in normal tissues from HIPED for FAM92B Gene

This gene is overexpressed in Frontal cortex (18.3), Bone marrow mesenchymal stem cell (9.5), and Urinary Bladder (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM92B Gene

SOURCE GeneReport for Unigene cluster for FAM92B Gene Hs.125713

genes like me logo Genes that share expression patterns with FAM92B: view

Protein tissue co-expression partners for FAM92B Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM92B Gene

Orthologs for FAM92B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM92B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM92B 35
  • 81.76 (n)
  • 80 (a)
FAM92B 36
  • 74 (a)
(Canis familiaris)
Mammalia FAM92B 35
  • 79.98 (n)
  • 75.27 (a)
FAM92B 36
  • 72 (a)
(Mus musculus)
Mammalia Fam92b 35
  • 83.07 (n)
  • 80.16 (a)
Fam92b 16
Fam92b 36
  • 71 (a)
(Pan troglodytes)
Mammalia FAM92B 35
  • 98.9 (n)
  • 97.7 (a)
FAM92B 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Fam92b 35
  • 80.82 (n)
  • 78.57 (a)
(Monodelphis domestica)
Mammalia FAM92B 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia FAM92B 36
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam92b 35
  • 64.96 (n)
  • 64.57 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.12567 35
fruit fly
(Drosophila melanogaster)
Insecta CG6405 36
  • 17 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11121 36
  • 29 (a)
Species with no ortholog for FAM92B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM92B Gene

Gene Tree for FAM92B (if available)
Gene Tree for FAM92B (if available)

Paralogs for FAM92B Gene

Paralogs for FAM92B Gene

(1) SIMAP similar genes for FAM92B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM92B: view

Variants for FAM92B Gene

Sequence variations from dbSNP and Humsavar for FAM92B Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs1010639 -- 85,098,251(-) GCTGC(C/G)TTGAC downstream-variant-500B
rs1466864 -- 85,100,004(+) CACCA(A/C)CCCTG intron-variant
rs3764278 -- 85,100,266(+) TGGGT(C/G)GGATC intron-variant
rs3764279 -- 85,100,335(+) AGGCC(C/T)GAGAC intron-variant
rs3764280 -- 85,103,320(+) CTCCA(A/G)CACCG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM92B Gene

Variant ID Type Subtype PubMed ID
nsv907087 CNV Loss 21882294
nsv907089 CNV Loss 21882294
nsv907090 CNV Loss 21882294
nsv907091 CNV Gain 21882294
nsv907092 CNV Loss 21882294
dgv2936n71 CNV Loss 21882294

Variation tolerance for FAM92B Gene

Residual Variation Intolerance Score: 79.71% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.65; 56.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM92B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM92B Gene

Disorders for FAM92B Gene

Relevant External Links for FAM92B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM92B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM92B Gene

Publications for FAM92B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in Canadian children and young adults. (PMID: 21472827) Amre D.K. … Levy E. (Inflamm. Bowel Dis. 2012) 67
  3. rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. (PMID: 19262523) Glas J. … Brand S. (Am. J. Gastroenterol. 2009) 67
  4. Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort. (PMID: 18580884) Roberts R.L. … Merriman T.R. (Genes Immun. 2008) 67
  5. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. (PMID: 17068223) Duerr R.H. … Cho J.H. (Science 2006) 67

Products for FAM92B Gene

Sources for FAM92B Gene

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