FAM92A1 Gene
protein-coding GIFtS: 43
GCID: GC08P094710 (predicted)
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family with sequence similarity 92, member A1
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Aliases
for FAM92A1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 92, Member A11 2 | | FLJ389791 | | Protein FAM92A12 |
Export aliases for FAM92A1 gene to outside databasesPrevious GC identifers: GC08P094783 GC08P094769 GC08P094785 GC08P089920 |
Summaries
for FAM92A1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM92A1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM92A1 gene promoter:
C/EBPbeta p53 Gfi-1 C/EBPalpha AREB6 POU2F1 FOXJ2 (long isoform) POU2F1a FOXJ2 ATF
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM92A1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM92A1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q22.1 Ensembl cytogenetic band: 8q22.1 HGNC cytogenetic band: 8q22.1FAM92A1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P094710: view genomic region
(about GC identifiers)
Start:
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94,710,789 bp from pter |
End:
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94,743,755 bp from pter |
Size:
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32,967 bases |
Orientation:
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plus strand |
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Proteins
for FAM92A1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F92A1_HUMAN, A1XBS5 (See
protein sequence)Recommended Name: Protein FAM92A1 Size: 289 amino acids; 33431 Da
Sequence caution: Sequence=AAH14598.2; Type=Erroneous initiation; Sequence=AAI08708.1; Type=Erroneous initiation;
Secondary accessions: A1XBS4 Q32ND3 Q6AHW7 Q8N8R1 Q96L09Alternative splicing: 5 isoforms: A1XBS5-1 A1XBS5-2 A1XBS5-3 A1XBS5-4 A1XBS5-5 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM92A1: NX_A1XBS5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A1XBS5
FAM92A1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_660312.2
ENSEMBL proteins: ENSP00000430217 ENSP00000428446 ENSP00000391671 ENSP00000429367 ENSP00000430069 ENSP00000352391 ENSP00000428739 ENSP00000401774 ENSP00000429722 ENSP00000428065 ENSP00000430812 ENSP00000427991 ENSP00000428633 ENSP00000428874 ENSP00000428751 ENSP00000429955
Human Recombinant Protein Products:
FAM92A1 Antibody Products:
Assay Products for FAM92A1: |
Protein
Domains /
Families
for FAM92A1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM92A1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry A1XBS5ProtoNet protein and cluster: A1XBS5 UniProtKB/Swiss-Prot: F92A1_HUMAN, A1XBS5Similarity: Belongs to the FAM92 family |
Function
for FAM92A1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92A1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92A1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM92A1 (NM_145269) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM92A1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM92A1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
FAM92A1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for FAM92A1:
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Pathways & Interactions
for FAM92A1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM92A1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for FAM92A1 (A1XBS53 ENSP000003916714) via UniProtKB, MINT, STRING, and/or I2DAbout this table
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Drugs & Compounds
for FAM92A1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM92A1
Search CenterWatch for drugs/clinical trials and news about FAM92A1 / F92A1
|
Transcripts
for FAM92A1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM92A1 gene: NM_145269.3 Unigene Cluster for FAM92A1: Family with sequence similarity 92, member A1 Hs.125038 [show with all ESTs]Unigene Representative Sequence: BG02515018 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000523475 ENST00000518829 ENST00000452913(uc022ayc.1 uc003yfw.4)
ENST00000518322(uc022ayd.1) ENST00000522324 ENST00000523577(uc003yfu.1)
ENST00000359421 ENST00000522803 ENST00000423990 ENST00000520937 ENST00000518116(uc003yfx.4)
ENST00000523453 ENST00000520955 ENST00000519135 ENST00000517718(uc010mar.3)
ENST00000521641 ENST00000519679 ENST00000520363
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92A1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92A1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM92A1 (NM_145269) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM92A1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM92A1 |
Additional cDNA sequence: BC108707.1 DQ327715.1 DQ327716.1 16 DOTS entries: DT.403498 DT.100710179 DT.100689924 DT.91947664 DT.455046 DT.99965020 DT.95259710 DT.86852205 DT.121477178 DT.121477268 DT.100755011 DT.121477172 DT.121477202 DT.95135290 DT.100035381 DT.320480 24/107 AceView cDNA sequences (see all 107): AA399381 CR621981 CA412376 AA955022 BU623224 BX094706 BP336432 BX377341 BX439644 AA336863 AI753444 AW960748 AI635390 AK096298 AI745371 AA425914 BQ021487 AI203171 BM842435 BP371225 BG771870 BM908235 AI802435 AI138555
GeneLoc Exon Structure
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Expression
for FAM92A1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM92A1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTATTTCACA
About this image
See FAM92A1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM92A1
SOURCE GeneReport for Unigene cluster: Hs.125038
SABiosciences Custom PCR Arrays for FAM92A1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM92A1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM92A1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM92A1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM92A1 |
Orthologs
for FAM92A1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for FAM92A1 gene from 6/21 species (see all 21) About this table
ENSEMBL Gene Tree for FAM92A1 (if available)
TreeFam Gene Tree for FAM92A1 (if available) |
Paralogs
for FAM92A1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM92A1 gene
- FAM92B2
1 SIMAP similar gene for FAM92A1 using alignment to 11 protein entries: F92A1_HUMAN (see all proteins):FAM92B
FAM92A1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for FAM92A1
PGOHUM00000257096 PGOHUM00000257097
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Genomic Variants
for FAM92A1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM92A1 (94710789 - 94743755 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM92A1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM92A1 |
|
Disorders
/ Diseases
for FAM92A1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM92A1 for disorders About GeneDecksing
2  diseases for FAM92A1: About MalaCardsrenal cell carcinoma carcinoma
1 disease from the University of Copenhagen DISEASES database for FAM92A1:Penis carcinoma Export disorders for FAM92A1 gene to outside databases
|
Publications
for FAM92A1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM92A1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM92A1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. (PubMed id 22832960)1 Service S.K....Freimer N.B. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Prokaryotic expression, purification of a new tumor-relative protein FAM92A1-289 and its characterization in renal cell carcinoma. (PubMed id 19059705)1 Liang S....Wei Y. (2009)
- Identification and characterization of two novel variants of the DUF1208 protein FAM92A1. (PubMed id 17646714)1 Ruan X.Z....Wei Y.Q. (2007)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for FAM92A1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM92A1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM92A1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM92A1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM92A1 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM92A1 gene:
Search GeneIP for patents involving FAM92A1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM92A1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM92A1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM92A1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM92A1 | | | OriGene Protein Over-expression Lysate for FAM92A1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM92A1 | | OriGene 3'-UTR Clone for FAM92A1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92A1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM92A1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM92A1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM92A1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM92A1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM92A1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM92A1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM92A1 |
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 | | | FAM92A1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | ThermoFisher Antibodies for FAM92A1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM92A1 |
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