Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM92A1 Gene

Aliases for FAM92A1 Gene

  • Family With Sequence Similarity 92 Member A1 2 3 5
  • Family With Sequence Similarity 92, Member A1 2

External Ids for FAM92A1 Gene

Previous GeneCards Identifiers for FAM92A1 Gene

  • GC08P094783
  • GC08P094769
  • GC08P094785
  • GC08P089920
  • GC08P094710

Summaries for FAM92A1 Gene

GeneCards Summary for FAM92A1 Gene

FAM92A1 (Family With Sequence Similarity 92 Member A1) is a Protein Coding gene. An important paralog of this gene is FAM92B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM92A1 Gene

Genomics for FAM92A1 Gene

Regulatory Elements for FAM92A1 Gene

Genomic Location for FAM92A1 Gene

Chromosome:
8
Start:
93,698,561 bp from pter
End:
93,731,527 bp from pter
Size:
32,967 bases
Orientation:
Plus strand

Genomic View for FAM92A1 Gene

Genes around FAM92A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM92A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM92A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM92A1 Gene

Proteins for FAM92A1 Gene

  • Protein details for FAM92A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1XBS5-F92A1_HUMAN
    Recommended name:
    Protein FAM92A1
    Protein Accession:
    A1XBS5
    Secondary Accessions:
    • A1XBS4
    • Q32ND3
    • Q6AHW7
    • Q8N8R1
    • Q96L09

    Protein attributes for FAM92A1 Gene

    Size:
    289 amino acids
    Molecular mass:
    33431 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH14598.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI08708.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM92A1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM92A1 Gene

Proteomics data for FAM92A1 Gene at MOPED

Post-translational modifications for FAM92A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM92A1 Gene

Domains & Families for FAM92A1 Gene

Protein Domains for FAM92A1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM92A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A1XBS5

UniProtKB/Swiss-Prot:

F92A1_HUMAN :
  • Belongs to the FAM92 family.
Family:
  • Belongs to the FAM92 family.
genes like me logo Genes that share domains with FAM92A1: view

No data available for Gene Families for FAM92A1 Gene

Function for FAM92A1 Gene

Phenotypes for FAM92A1 Gene

genes like me logo Genes that share phenotypes with FAM92A1: view

Animal Model Products

CRISPR Products

miRNA for FAM92A1 Gene

miRTarBase miRNAs that target FAM92A1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM92A1 Gene

Localization for FAM92A1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM92A1 Gene COMPARTMENTS Subcellular localization image for FAM92A1 gene
Compartment Confidence
mitochondrion 3
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM92A1 Gene

Pathways & Interactions for FAM92A1 Gene

SuperPathways for FAM92A1 Gene

No Data Available

Interacting Proteins for FAM92A1 Gene

Gene Ontology (GO) - Biological Process for FAM92A1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM92A1 Gene

Drugs & Compounds for FAM92A1 Gene

No Compound Related Data Available

Transcripts for FAM92A1 Gene

Unigene Clusters for FAM92A1 Gene

Family with sequence similarity 92, member A1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM92A1 Gene

No ASD Table

Relevant External Links for FAM92A1 Gene

GeneLoc Exon Structure for
FAM92A1
ECgene alternative splicing isoforms for
FAM92A1

Expression for FAM92A1 Gene

mRNA expression in normal human tissues for FAM92A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM92A1 Gene

This gene is overexpressed in Testis (x5.6).

Protein differential expression in normal tissues from HIPED for FAM92A1 Gene

This gene is overexpressed in Pancreatic juice (37.6) and Heart (20.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM92A1 Gene



SOURCE GeneReport for Unigene cluster for FAM92A1 Gene Hs.125038

genes like me logo Genes that share expression patterns with FAM92A1: view

Protein tissue co-expression partners for FAM92A1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM92A1 Gene

Orthologs for FAM92A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM92A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM92A1 36
  • 97 (a)
OneToOne
FAM92A1 35
  • 99.77 (n)
  • 99.65 (a)
cow
(Bos Taurus)
Mammalia FAM92A1 36
  • 88 (a)
OneToMany
FAM92A1 36
  • 83 (a)
OneToMany
FAM92A1 35
  • 90 (n)
  • 91.11 (a)
dog
(Canis familiaris)
Mammalia FAM92A1 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam92a 16
Fam92a 36
  • 70 (a)
OneToOne
Fam92a 35
  • 86.91 (n)
  • 88.52 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 85 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 83 (a)
OneToMany
-- 36
  • 88 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia FAM92A1 36
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam92a1 35
  • 87.65 (n)
  • 86.67 (a)
chicken
(Gallus gallus)
Aves FAM92A1 35
  • 77.53 (n)
  • 79.26 (a)
FAM92A1 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM92A1 36
  • 74 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.11471 35
tropical clawed frog
(Silurana tropicalis)
Amphibia fam92a1 35
  • 71.95 (n)
  • 76.55 (a)
Str.4426 35
zebrafish
(Danio rerio)
Actinopterygii fam92a1 36
  • 63 (a)
OneToOne
fam92a1 35
  • 67.16 (n)
  • 68.89 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009881 35
  • 42.67 (n)
  • 37.5 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG6405 35
  • 44.75 (n)
  • 34.7 (a)
CG6405 36
  • 22 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11121 36
  • 37 (a)
OneToMany
Species with no ortholog for FAM92A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM92A1 Gene

ENSEMBL:
Gene Tree for FAM92A1 (if available)
TreeFam:
Gene Tree for FAM92A1 (if available)

Paralogs for FAM92A1 Gene

Paralogs for FAM92A1 Gene

Pseudogenes.org Pseudogenes for FAM92A1 Gene

genes like me logo Genes that share paralogs with FAM92A1: view

Variants for FAM92A1 Gene

Sequence variations from dbSNP and Humsavar for FAM92A1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs36117362 - 93,726,401(+) TTTCC(A/G)AAATT nc-transcript-variant, reference, missense
rs1051914 -- 93,728,838(+) TCAAT(A/G)TTTTA nc-transcript-variant, utr-variant-3-prime
rs2914948 -- 93,707,352(-) ATCTT(C/T)TATCA intron-variant, downstream-variant-500B
rs2914952 -- 93,729,524(+) TTTGT(A/C)AAGTT downstream-variant-500B
rs2976352 -- 93,714,640(-) GGGGC(C/T)ATAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM92A1 Gene

Variant ID Type Subtype PubMed ID
nsv528872 CNV Loss 19592680
dgv7834n71 CNV Loss 21882294
nsv831399 CNV Loss 17160897

Variation tolerance for FAM92A1 Gene

Residual Variation Intolerance Score: 52.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.44; 71.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM92A1 Gene

HapMap Linkage Disequilibrium report
FAM92A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM92A1 Gene

Disorders for FAM92A1 Gene

Relevant External Links for FAM92A1

Genetic Association Database (GAD)
FAM92A1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM92A1

No disorders were found for FAM92A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM92A1 Gene

Publications for FAM92A1 Gene

  1. Identification and characterization of two novel variants of the DUF1208 protein FAM92A1. (PMID: 17646714) Ruan X.Z. … Wei Y.Q. (Mol. Cells 2007) 2 3 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. (PMID: 22832960) Service S.K. … Freimer N.B. (Transl Psychiatry 2012) 3
  4. An empirical framework for binary interactome mapping. (PMID: 19060904) Venkatesan K. … Vidal M. (Nat. Methods 2009) 3
  5. Prokaryotic expression, purification of a new tumor-relative protein FAM92A1-289 and its characterization in renal cell carcinoma. (PMID: 19059705) Liang S. … Wei Y. (Cancer Lett. 2009) 3

Products for FAM92A1 Gene

Sources for FAM92A1 Gene

Back to Top

Content