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Aliases for FAM92A1 Gene

Aliases for FAM92A1 Gene

  • Family With Sequence Similarity 92 Member A1 2 3 5
  • Family With Sequence Similarity 92, Member A1 2

External Ids for FAM92A1 Gene

Previous GeneCards Identifiers for FAM92A1 Gene

  • GC08P094783
  • GC08P094769
  • GC08P094785
  • GC08P089920
  • GC08P094710

Summaries for FAM92A1 Gene

GeneCards Summary for FAM92A1 Gene

FAM92A1 (Family With Sequence Similarity 92 Member A1) is a Protein Coding gene. An important paralog of this gene is FAM92B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM92A1 Gene

Genomics for FAM92A1 Gene

Regulatory Elements for FAM92A1 Gene

Enhancers for FAM92A1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around FAM92A1 on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM92A1 Gene

93,698,561 bp from pter
93,731,527 bp from pter
32,967 bases
Plus strand

Genomic View for FAM92A1 Gene

Genes around FAM92A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM92A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM92A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM92A1 Gene

Proteins for FAM92A1 Gene

  • Protein details for FAM92A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM92A1
    Protein Accession:
    Secondary Accessions:
    • A1XBS4
    • Q32ND3
    • Q6AHW7
    • Q8N8R1
    • Q96L09

    Protein attributes for FAM92A1 Gene

    289 amino acids
    Molecular mass:
    33431 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH14598.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI08708.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM92A1 Gene


neXtProt entry for FAM92A1 Gene

Post-translational modifications for FAM92A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM92A1 Gene

Domains & Families for FAM92A1 Gene

Protein Domains for FAM92A1 Gene


Suggested Antigen Peptide Sequences for FAM92A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM92 family.
  • Belongs to the FAM92 family.
genes like me logo Genes that share domains with FAM92A1: view

No data available for Gene Families for FAM92A1 Gene

Function for FAM92A1 Gene

Gene Ontology (GO) - Molecular Function for FAM92A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM92A1: view

Phenotypes for FAM92A1 Gene

genes like me logo Genes that share phenotypes with FAM92A1: view

Animal Model Products

CRISPR Products

miRNA for FAM92A1 Gene

miRTarBase miRNAs that target FAM92A1

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM92A1 Gene

Localization for FAM92A1 Gene

Subcellular locations from

Jensen Localization Image for FAM92A1 Gene COMPARTMENTS Subcellular localization image for FAM92A1 gene
Compartment Confidence
mitochondrion 3
cytosol 2
nucleus 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM92A1 Gene

Pathways & Interactions for FAM92A1 Gene

SuperPathways for FAM92A1 Gene

No Data Available

Interacting Proteins for FAM92A1 Gene

Gene Ontology (GO) - Biological Process for FAM92A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM92A1 Gene

Drugs & Compounds for FAM92A1 Gene

No Compound Related Data Available

Transcripts for FAM92A1 Gene

Unigene Clusters for FAM92A1 Gene

Family with sequence similarity 92, member A1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM92A1 Gene

No ASD Table

Relevant External Links for FAM92A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM92A1 Gene

mRNA expression in normal human tissues for FAM92A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM92A1 Gene

This gene is overexpressed in Testis (x5.6).

Protein differential expression in normal tissues from HIPED for FAM92A1 Gene

This gene is overexpressed in Pancreatic juice (37.6) and Heart (20.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM92A1 Gene

Protein tissue co-expression partners for FAM92A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM92A1 Gene:


SOURCE GeneReport for Unigene cluster for FAM92A1 Gene:

genes like me logo Genes that share expression patterns with FAM92A1: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for FAM92A1 Gene

Orthologs for FAM92A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM92A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM92A1 34
  • 90 (n)
  • 91.11 (a)
FAM92A1 35
  • 88 (a)
FAM92A1 35
  • 83 (a)
(Mus musculus)
Mammalia Fam92a 34
  • 86.91 (n)
  • 88.52 (a)
Fam92a 16
Fam92a 35
  • 70 (a)
(Pan troglodytes)
Mammalia FAM92A1 34
  • 99.77 (n)
  • 99.65 (a)
FAM92A1 35
  • 97 (a)
(Rattus norvegicus)
Mammalia Fam92a1 34
  • 87.65 (n)
  • 86.67 (a)
(Canis familiaris)
Mammalia FAM92A1 35
  • 86 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 85 (a)
-- 35
  • 82 (a)
-- 35
  • 82 (a)
-- 35
  • 83 (a)
-- 35
  • 88 (a)
-- 35
  • 82 (a)
-- 35
  • 82 (a)
(Ornithorhynchus anatinus)
Mammalia FAM92A1 35
  • 76 (a)
(Gallus gallus)
Aves FAM92A1 34
  • 77.53 (n)
  • 79.26 (a)
FAM92A1 35
  • 73 (a)
(Anolis carolinensis)
Reptilia FAM92A1 35
  • 74 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam92a1 34
  • 71.95 (n)
  • 76.55 (a)
Str.4426 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.11471 34
(Danio rerio)
Actinopterygii fam92a1 34
  • 67.16 (n)
  • 68.89 (a)
fam92a1 35
  • 63 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009881 34
  • 42.67 (n)
  • 37.5 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG6405 34
  • 44.75 (n)
  • 34.7 (a)
CG6405 35
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11121 35
  • 37 (a)
Species where no ortholog for FAM92A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM92A1 Gene

Gene Tree for FAM92A1 (if available)
Gene Tree for FAM92A1 (if available)

Paralogs for FAM92A1 Gene

Paralogs for FAM92A1 Gene Pseudogenes for FAM92A1 Gene

genes like me logo Genes that share paralogs with FAM92A1: view

Variants for FAM92A1 Gene

Sequence variations from dbSNP and Humsavar for FAM92A1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs36117362 - 93,726,401(+) TTTCC(A/G)AAATT nc-transcript-variant, reference, missense
rs1051914 -- 93,728,838(+) TCAAT(A/G)TTTTA nc-transcript-variant, utr-variant-3-prime
rs2914940 -- 93,719,598(-) TCAGA(A/G)TCCTG intron-variant
rs2914941 -- 93,716,983(-) TAACA(C/G)TAAAG intron-variant
rs2914942 -- 93,714,189(-) GAAGT(A/T)TAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM92A1 Gene

Variant ID Type Subtype PubMed ID
esv3543858 CNV deletion 23714750
nsv1022473 CNV loss 25217958
nsv528872 CNV loss 19592680
nsv831399 CNV loss 17160897

Variation tolerance for FAM92A1 Gene

Residual Variation Intolerance Score: 52.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.44; 71.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM92A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM92A1 Gene

Disorders for FAM92A1 Gene

Relevant External Links for FAM92A1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM92A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM92A1 Gene

Publications for FAM92A1 Gene

  1. Identification and characterization of two novel variants of the DUF1208 protein FAM92A1. (PMID: 17646714) Ruan X.Z. … Wei Y.Q. (Mol. Cells 2007) 2 3 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65
  4. A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. (PMID: 22832960) Service S.K. … Freimer N.B. (Transl Psychiatry 2012) 3 65
  5. Prokaryotic expression, purification of a new tumor-relative protein FAM92A1-289 and its characterization in renal cell carcinoma. (PMID: 19059705) Liang S. … Wei Y. (Cancer Lett. 2009) 3 65

Products for FAM92A1 Gene

Sources for FAM92A1 Gene

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