Aliases for FAM92A Gene
Aliases for FAM92A Gene
External Ids for FAM92A Gene
- HGNC: 30452
- Entrez Gene: 137392
- Ensembl: ENSG00000188343
- OMIM: 617273
- UniProtKB: A1XBS5
Previous HGNC Symbols for FAM92A Gene
- FAM92A1
Summaries for FAM92A Gene
GeneCards Summary for FAM92A Gene
FAM92A (Family With Sequence Similarity 92 Member A) is a Protein Coding gene. An important paralog of this gene is FAM92B.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM92A Gene
Genomics for FAM92A Gene
Regulatory Elements for FAM92A Gene
Enhancers for FAM92A Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM92A on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FAM92A Gene
- Chromosome:
- 8
- Start:
- 93,698,561 bp from pter
- End:
- 93,731,527 bp from pter
- Size:
- 32,967 bases
- Orientation:
- Plus strand
Genomic View for FAM92A Gene
Genes around FAM92A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q22.1 by Ensembl
- 8q22.1 by Entrez Gene
- 8q22.1 by HGNC
FAM92A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM92A Gene
Proteins for FAM92A Gene
-
Protein details for FAM92A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A1XBS5-F92A1_HUMAN
- Recommended name:
- Protein FAM92A1
- Protein Accession:
- A1XBS5
- A1XBS4
- Q32ND3
- Q6AHW7
- Q8N8R1
- Q96L09
Protein attributes for FAM92A Gene
- Size:
- 289 amino acids
- Molecular mass:
- 33431 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH14598.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI08708.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Post-translational modifications for FAM92A Gene
Other Protein References for FAM92A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM92A
- Invitrogen Antibodies for FAM92A
- Search GeneTex for Antibodies for FAM92A
Protein Products
-
OriGene Purified Proteins for FAM92A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM92A
- Origene Custom Protein Services for FAM92A
- Search GeneTex for Proteins for FAM92A
Assay Products
No data available for DME Specific Peptides for FAM92A Gene
Domains & Families for FAM92A Gene
Protein Domains for FAM92A Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM92A Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
A1XBS5- Family:
-
- Belongs to the FAM92 family.
No data available for Gene Families for FAM92A Gene
Function for FAM92A Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 25416956 |
Phenotypes for FAM92A Gene
- MGI mutant phenotypes for FAM92A:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FAM92A:
Animal Models for FAM92A Gene
- MGI Knock Outs for FAM92A:
-
- Fam92a tm1b(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM92A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92A gene
- Search ViGene Biosciences for FAM92A
CRISPR Products
-
OriGene CRISPR knockouts for FAM92A
- GenScript: Design CRISPR guide RNA sequences for FAM92A
miRNA for FAM92A Gene
- miRTarBase miRNAs that target FAM92A
miRNA Products
- Search ViGene Biosciences for FAM92A
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM92A
- Browse OriGene Inhibitory RNA Products For FAM92A
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92A gene
Clone Products
-
OriGene ORF clones in human for FAM92A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FAM92A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM92A
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM92A gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM92A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92A gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FAM92A Gene
Localization for FAM92A Gene
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| nucleus | 5 |
| mitochondrion | 3 |
| cytosol | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005737 | cytoplasm | IDA | 27528616 |
| GO:0005814 | centriole | IDA | 27528616 |
| GO:0036064 | ciliary basal body | IEA,IDA | -- |
| GO:0097546 | ciliary base | IDA | 27528616 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM92A Gene
Pathways & Interactions for FAM92A Gene
No Data Available
Interacting Proteins for FAM92A Gene
Selected Interacting proteins:
A1XBS5-F92A1_HUMAN
ENSP00000429367
for FAM92A Gene via
IID
STRING
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0060271 | cilium assembly | IMP | 27528616 |
No data available for Pathways by source and SIGNOR curated interactions for FAM92A Gene
Transcripts for FAM92A Gene
mRNA/cDNA for FAM92A Gene
- (3) REFSEQ mRNAs :
- (107) Selected AceView cDNA sequences:
- (19) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for FAM92A
- GenScript: Design CRISPR guide RNA sequences for FAM92A
miRNA Products
- Search ViGene Biosciences for FAM92A
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM92A
- Browse OriGene Inhibitory RNA Products For FAM92A
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM92A gene
Clone Products
-
OriGene ORF clones in human for FAM92A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FAM92A
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM92A Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM92A Gene:
FAM92AEvidence on tissue expression from TISSUES for FAM92A Gene
- Blood(5)
- Nervous system(4.4)
No Expression Related Data Available
Primer Products
-
OriGene qPCR primer pairs for FAM92A
-
OriGene qPCR primer pairs and template standards for FAM92A
No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM92A Gene
Orthologs for FAM92A Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM92A1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM92A1 34 35 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Fam92a1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam92a 34 16 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM92A1 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM92A1 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FAM92A1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FAM92A1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam92a1 34 |
|
||
| Str.4426 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.11471 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fam92a1 34 35 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG6405 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP009881 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.11121 35 |
|
OneToMany |
- Species where no ortholog for FAM92A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM92A Gene
Pseudogenes.org Pseudogenes for FAM92A Gene
Variants for FAM92A Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000012792 | -- | 93,731,513(+) | ATCAA(A/C)TTTAC | utr-variant-3-prime | |
| rs1000162151 | -- | 93,715,353(+) | AGTAG(C/T)TGACA | intron-variant | |
| rs1000342649 | -- | 93,720,525(+) | AAACA(C/T)TACAG | intron-variant | |
| rs1000400155 | -- | 93,727,126(+) | ACAAA(A/G)GCAGG | intron-variant, utr-variant-3-prime | |
| rs1000514042 | -- | 93,714,296(+) | TTTTT(A/G)TATAC | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3543858 | CNV | deletion | 23714750 |
| nsv1022473 | CNV | loss | 25217958 |
| nsv528872 | CNV | loss | 19592680 |
| nsv831399 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
52.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.44;
71.43% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM92A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM92A
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM92A Gene
Disorders for FAM92A Gene
Relevant External Links for FAM92A
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM92A
No disorders were found for FAM92A Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM92A Gene
Publications for FAM92A Gene
- BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis. (PMID: 27528616) Li F.Q. … Takemaru K.I. (Mol. Cell. Biol. 2016) 2 3 64
- Identification and characterization of two novel variants of the DUF1208 protein FAM92A1. (PMID: 17646714) Ruan X.Z. … Wei Y.Q. (Mol. Cells 2007) 2 3 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The Tumor-promoting Effects of FAM92A1-289 in Cervical Carcinoma Cells. (PMID: 27798880) Gui H. … Ruan X.Z. (Anticancer Res. 2016) 3 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
Products for FAM92A Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Immunoprecipitation Assays
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- Browse Proteome Profiler Antibody Arrays
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- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FAM92A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM92A
- Origene Custom Protein Services for FAM92A
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM92A
- Browse OriGene Inhibitory RNA Products For FAM92A
- OriGene qPCR primer pairs and template standards for FAM92A
- OriGene qPCR primer pairs for FAM92A
- OriGene CRISPR knockouts for FAM92A
- OriGene ORF clones in human for FAM92A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FAM92A
- GenScript: Next-day shipping cDNA ORF clone for FAM92A in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM92A
- GenScript Custom Assay Services for FAM92A
- GenScript Custom overexpressing Cell Line Services for FAM92A
- GenScript: Design CRISPR guide RNA sequences for FAM92A
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- CloneReady with Over 120,000 Genes
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- Plasmid Preparation
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- Sino Biological Human cDNA Clone for FAM92A
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FAM92A
- Novus Biologicals proteins and lysates for FAM92A
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for FAM92A gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM92A gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM92A gene
- Search ViGene Biosciences for FAM92A
- Horizon Cell Lines for FAM92A
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM92A
- VectorBuilder custom plasmid, inducible vectors for FAM92A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM92A
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM92A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer