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Aliases for FAM92A Gene

Aliases for FAM92A Gene

  • Family With Sequence Similarity 92 Member A 2 3 5
  • Family With Sequence Similarity 92 Member A1 2 3
  • FAM92A1 3 4
  • Family With Sequence Similarity 92, Member A1 2
  • Protein FAM92A1 3

External Ids for FAM92A Gene

Previous HGNC Symbols for FAM92A Gene

  • FAM92A1

Summaries for FAM92A Gene

GeneCards Summary for FAM92A Gene

FAM92A (Family With Sequence Similarity 92 Member A) is a Protein Coding gene. An important paralog of this gene is FAM92B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM92A Gene

Genomics for FAM92A Gene

Regulatory Elements for FAM92A Gene

Enhancers for FAM92A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F093956 1.4 FANTOM5 Ensembl ENCODE 11.1 +260.4 260359 5.0 SIN3A RAD21 YY1 RARA ZNF366 CBX5 ZNF654 REST NR2F2 SMARCA4 LINC00535 FAM92A LOC105375645 RBM12B PDP1 ENSG00000253722 GEM RPL34P18 ENSG00000275386
GH08F094474 1.1 ENCODE 13.2 +776.4 776400 1.8 HDGF PKNOX1 MLX WRNIP1 ARID4B SIN3A ZNF2 ZNF143 FOS ZNF263 INTS8 KIAA1429 FAM92A ENSG00000253704 RAD54B GC08P094456
GH08F093915 1.1 ENCODE 11 +218.8 218800 3.8 HDGF PKNOX1 ATF1 ARID4B SIN3A FEZF1 DMAP1 ZNF48 BRCA1 ZNF2 PDP1 FAM92A LINC00535 MIR378D2 PSMA2P2
GH08F093900 1.1 Ensembl ENCODE 10.1 +205.3 205307 6.7 PKNOX1 TBL1XR1 JUN ZNF175 CEBPG ZNF766 CBX5 PRDM10 NR2F6 FOS PDP1 LINC00535 FAM92A FSBP LOC105375646 GC08M093861
GH08F093943 1.1 Ensembl ENCODE 9.9 +245.6 245633 2.2 ESRRA JUN ZNF175 SIN3A CEBPG EBF1 ZNF316 GATA3 FOS ZNF584 FAM92A LINC00535 PDP1 PSMA2P2 PIR51498
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM92A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM92A Gene

Chromosome:
8
Start:
93,698,561 bp from pter
End:
93,731,527 bp from pter
Size:
32,967 bases
Orientation:
Plus strand

Genomic View for FAM92A Gene

Genes around FAM92A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM92A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM92A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM92A Gene

Proteins for FAM92A Gene

  • Protein details for FAM92A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A1XBS5-F92A1_HUMAN
    Recommended name:
    Protein FAM92A1
    Protein Accession:
    A1XBS5
    Secondary Accessions:
    • A1XBS4
    • Q32ND3
    • Q6AHW7
    • Q8N8R1
    • Q96L09

    Protein attributes for FAM92A Gene

    Size:
    289 amino acids
    Molecular mass:
    33431 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH14598.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI08708.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM92A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM92A Gene

Post-translational modifications for FAM92A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM92A Gene

Domains & Families for FAM92A Gene

Protein Domains for FAM92A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM92A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A1XBS5

UniProtKB/Swiss-Prot:

F92A1_HUMAN :
  • Belongs to the FAM92 family.
Family:
  • Belongs to the FAM92 family.
genes like me logo Genes that share domains with FAM92A: view

No data available for Gene Families for FAM92A Gene

Function for FAM92A Gene

Gene Ontology (GO) - Molecular Function for FAM92A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM92A: view

Phenotypes for FAM92A Gene

genes like me logo Genes that share phenotypes with FAM92A: view

Animal Models for FAM92A Gene

MGI Knock Outs for FAM92A:

Animal Model Products

miRNA for FAM92A Gene

miRTarBase miRNAs that target FAM92A

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FAM92A Gene

Localization for FAM92A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM92A gene
Compartment Confidence
cytoskeleton 5
nucleus 5
mitochondrion 3
cytosol 2
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM92A Gene

Pathways & Interactions for FAM92A Gene

SuperPathways for FAM92A Gene

No Data Available

Interacting Proteins for FAM92A Gene

Gene Ontology (GO) - Biological Process for FAM92A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM92A Gene

Transcripts for FAM92A Gene

Unigene Clusters for FAM92A Gene

Family with sequence similarity 92, member A1:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM92A Gene

No ASD Table

Relevant External Links for FAM92A Gene

GeneLoc Exon Structure for
FAM92A
ECgene alternative splicing isoforms for
FAM92A

Expression for FAM92A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM92A Gene:

FAM92A

SOURCE GeneReport for Unigene cluster for FAM92A Gene:

Hs.125038
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM92A Gene

Orthologs for FAM92A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM92A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM92A1 34 35
  • 99.77 (n)
cow
(Bos Taurus)
Mammalia FAM92A1 34 35 35
  • 90 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 88 (a)
OneToMany
-- 35
  • 85 (a)
OneToMany
-- 35
  • 83 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
-- 35
  • 82 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam92a1 34
  • 87.65 (n)
mouse
(Mus musculus)
Mammalia Fam92a 34 16 35
  • 86.91 (n)
dog
(Canis familiaris)
Mammalia FAM92A1 35
  • 86 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM92A1 35
  • 76 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM92A1 34 35
  • 77.53 (n)
lizard
(Anolis carolinensis)
Reptilia FAM92A1 35
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam92a1 34
  • 71.95 (n)
Str.4426 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.11471 34
zebrafish
(Danio rerio)
Actinopterygii fam92a1 34 35
  • 67.16 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG6405 34 35
  • 44.75 (n)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009881 34
  • 42.67 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.11121 35
  • 37 (a)
OneToMany
Species where no ortholog for FAM92A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM92A Gene

ENSEMBL:
Gene Tree for FAM92A (if available)
TreeFam:
Gene Tree for FAM92A (if available)

Paralogs for FAM92A Gene

Paralogs for FAM92A Gene

Pseudogenes.org Pseudogenes for FAM92A Gene

genes like me logo Genes that share paralogs with FAM92A: view

Variants for FAM92A Gene

Sequence variations from dbSNP and Humsavar for FAM92A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10105040 -- 93,698,865(+) TACAC(G/T)GCAAA intron-variant, upstream-variant-2KB
rs1051914 -- 93,728,838(+) TCAAT(A/G)TTTTA nc-transcript-variant, utr-variant-3-prime
rs10956879 -- 93,720,224(+) TAATC(C/T)GCCCG intron-variant
rs111240825 -- 93,716,961(+) TGTTA(A/G)TCAAA intron-variant
rs111546999 -- 93,717,469(+) ATTGT(A/G)AATCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM92A Gene

Variant ID Type Subtype PubMed ID
nsv831399 CNV loss 17160897
nsv528872 CNV loss 19592680
nsv1022473 CNV loss 25217958
esv3543858 CNV deletion 23714750

Variation tolerance for FAM92A Gene

Residual Variation Intolerance Score: 52.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.44; 71.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM92A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM92A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM92A Gene

Disorders for FAM92A Gene

Relevant External Links for FAM92A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM92A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM92A

No disorders were found for FAM92A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM92A Gene

Publications for FAM92A Gene

  1. BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis. (PMID: 27528616) Li F.Q. … Takemaru K.I. (Mol. Cell. Biol. 2016) 2 3 64
  2. Identification and characterization of two novel variants of the DUF1208 protein FAM92A1. (PMID: 17646714) Ruan X.Z. … Wei Y.Q. (Mol. Cells 2007) 2 3 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  5. A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. (PMID: 22832960) Service S.K. … Freimer N.B. (Transl Psychiatry 2012) 3 64

Products for FAM92A Gene

Sources for FAM92A Gene

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