FAM91A1 Gene
protein-coding GIFtS: 41
GCID: GC08P124780
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family with sequence similarity 91, member A1
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Aliases
for FAM91A1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 91, Member A11 2 | | FLJ237901 | | Protein FAM91A12 | | Skeletal Muscle Cells Re-Entry Induced2 |
Export aliases for FAM91A1 gene to outside databasesPrevious GC identifers: GC08P124860 GC08P120107 |
Summaries
for FAM91A1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM91A1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008046.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM91A1 gene promoter:
STAT1 STAT1beta CUTL1 STAT1alpha RORalpha2 GATA-1 POU2F1 Ik-2 POU2F1a RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM91A1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM91A1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q24.13 Ensembl cytogenetic band: 8q24.13 HGNC cytogenetic band: 8q24.13FAM91A1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08P124780: view genomic region
(about GC identifiers)
Start:
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124,780,696 bp from pter |
End:
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124,827,692 bp from pter |
Size:
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46,997 bases |
Orientation:
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plus strand |
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Proteins
for FAM91A1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F91A1_HUMAN, Q658Y4 (See
protein sequence)Recommended Name: Protein FAM91A1 Size: 838 amino acids; 93909 Da
Sequence caution: Sequence=BAB85063.1; Type=Erroneous initiation;
Secondary accessions: B6YY23 Q658T5 Q8TE89Explore the universe of human proteins at neXtProt for FAM91A1: NX_Q658Y4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q658Y4
FAM91A1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_659400.2
ENSEMBL proteins: ENSP00000429491 ENSP00000335082 ENSP00000429784 ENSP00000430158 ENSP00000431097
Human Recombinant Protein Products for FAM91A1:
FAM91A1 Antibody Products:
Assay Products for FAM91A1: |
Protein
Domains /
Families
for FAM91A1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q658Y4 UniProtKB/Swiss-Prot: F91A1_HUMAN, Q658Y4Similarity: Belongs to the FAM91 family |
Function
for FAM91A1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM91A1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM91A1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM91A1 (NM_144963) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM91A1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM91A1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM91A1 |
|
Pathways & Interactions
for FAM91A1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM91A1
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
5/6 Interacting proteins for FAM91A1 (Q658Y43 ENSP000003350824) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
|
Drugs & Compounds
for FAM91A1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM91A1
Search CenterWatch for drugs/clinical trials and news about FAM91A1 / F91A1
|
Transcripts
for FAM91A1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM91A1 gene: NM_144963.2 Unigene Cluster for FAM91A1: Family with sequence similarity 91, member A1 Hs.459174 [show with all ESTs]Unigene Representative Sequence: AL8329998 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000521166(uc011lik.1) ENST00000334705(uc003yqv.3 uc011lil.2)
ENST00000519721 ENST00000521704 ENST00000517912 ENST00000518333 ENST00000518976
ENST00000520246
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM91A1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM91A1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM91A1 (NM_144963) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM91A1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM91A1 |
Additional cDNA sequence: AK074370.1 AK300603.1 AL832830.1 AL832999.1 BC030520.1 BC144630.1 DQ228141.1 9 DOTS entries: DT.100818566 DT.97768720 DT.92422857 DT.70104629 DT.95372824 DT.121481344 DT.40225130 DT.91988771 DT.95160693 24/228 AceView cDNA sequences (see all 228): Z42169 BG390704 AW629098 AW889226 AW889177 AW271637 AI126250 CA416310 CA413860 AA731730 AW243442 AI953896 AW778887 AI392784 AI925261 AA577191 CB215998 CA426607 AA604757 BM856917 BU752334 T34245 AI801129 AK074370
GeneLoc Exon Structure
|
Expression
for FAM91A1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM91A1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTACAAATA
About this image
See FAM91A1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM91A1
SOURCE GeneReport for Unigene cluster: Hs.459174
SABiosciences Custom PCR Arrays for FAM91A1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM91A1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM91A1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM91A1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM91A1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM91A1 |
Orthologs
for FAM91A1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM91A1 gene from 9/25 species (see all 25) About this table
ENSEMBL Gene Tree for FAM91A1 (if available)
TreeFam Gene Tree for FAM91A1 (if available) |
Paralogs
for FAM91A1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM91A1 gene
1 SIMAP similar gene for FAM91A1 using alignment to 6 protein entries: F91A1_HUMAN (see all proteins):FAM91A2
FAM91A1 for paralogs About GeneDecksing
5/9 Pseudogenes.org Pseudogenes for FAM91A1 (see all 9)
PGOHUM00000256670 PGOHUM00000244909 PGOHUM00000244974 PGOHUM00000256882 PGOHUM00000256883
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Genomic Variants
for FAM91A1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM91A1 (124780696 - 124827692 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM91A1: --
Human Gene Mutation Database (HGMD): FAM91A1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM91A1 |
|
Disorders
/ Diseases
for FAM91A1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM91A1 for disorders About GeneDecksing
2  diseases for FAM91A1: About MalaCardspancreatic cancer pancreatitis
Export disorders for FAM91A1 gene to outside databases
|
Publications
for FAM91A1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM91A1 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with FAM91A1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)1, 2 Nusbaum C....Lander E.S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Genome-wide association study of pancreatic cancer in Japanese population. (PubMed id 20686608)1 Low S.K....Sakamoto H. (2010)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
- A genome-wide study of common SNPs and CNVs in cognit ive performance in the CANTAB. (PubMed id 19734545)1 Need A.C....Goldstein D.B. (2009)
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External Searches for FAM91A1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM91A1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM91A1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM91A1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM91A1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM91A1 gene:
Search GeneIP for patents involving FAM91A1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM91A1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM91A1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM91A1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM91A1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM91A1 | | OriGene 3'-UTR Clone for FAM91A1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM91A1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM91A1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM91A1 | | OriGene Custom Protein Services for FAM91A1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM91A1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM91A1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM91A1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM91A1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM91A1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM91A1 |
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| | | | Search Tocris compounds for FAM91A1 |
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 | | | FAM91A1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM91A1 |
|  |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM91A1 |
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