Aliases for FAM91A1 Gene
Aliases for FAM91A1 Gene
External Ids for FAM91A1 Gene
- HGNC: 26306
- Entrez Gene: 157769
- Ensembl: ENSG00000176853
- UniProtKB: Q658Y4
Previous GeneCards Identifiers for FAM91A1 Gene
- GC08P124860
- GC08P120107
- GC08P124780
Summaries for FAM91A1 Gene
GeneCards Summary for FAM91A1 Gene
FAM91A1 (Family With Sequence Similarity 91 Member A1) is a Protein Coding gene. Among its related pathways are Gastric Cancer Network 2.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM91A1 Gene
Genomics for FAM91A1 Gene
Regulatory Elements for FAM91A1 Gene
Enhancers for FAM91A1 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM91A1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM91A1 gene promoter:
Regulatory Element Products
Genomic Location for FAM91A1 Gene
- Chromosome:
- 8
- Start:
- 123,768,439 bp from pter
- End:
- 123,815,452 bp from pter
- Size:
- 47,014 bases
- Orientation:
- Plus strand
Genomic View for FAM91A1 Gene
Genes around FAM91A1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.13 by Ensembl
- 8q24.13 by Entrez Gene
- 8q24.13 by HGNC
FAM91A1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM91A1 Gene
Proteins for FAM91A1 Gene
-
Protein details for FAM91A1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q658Y4-F91A1_HUMAN
- Recommended name:
- Protein FAM91A1
- Protein Accession:
- Q658Y4
- B6YY23
- Q658T5
- Q8TE89
Protein attributes for FAM91A1 Gene
- Size:
- 838 amino acids
- Molecular mass:
- 93909 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAB85063.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for FAM91A1 Gene
Post-translational modifications for FAM91A1 Gene
Other Protein References for FAM91A1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM91A1
-
Abcam antibodies for FAM91A1
- Invitrogen Antibodies for FAM91A1
- Search GeneTex for Antibodies for FAM91A1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAM91A1
- Origene Custom Protein Services for FAM91A1
- Novus Biologicals proteins for FAM91A1
- Search GeneTex for Proteins for FAM91A1
Assay Products
No data available for DME Specific Peptides for FAM91A1 Gene
Domains & Families for FAM91A1 Gene
Protein Domains for FAM91A1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM91A1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q658Y4- Family:
-
- Belongs to the FAM91 family.
No data available for Gene Families for FAM91A1 Gene
Function for FAM91A1 Gene
Phenotypes for FAM91A1 Gene
- MGI mutant phenotypes for FAM91A1:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FAM91A1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM91A1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM91A1 gene
- Search ViGene Biosciences for FAM91A1
CRISPR Products
-
OriGene CRISPR knockouts for FAM91A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM91A1
- GenScript: Design CRISPR guide RNA sequences for FAM91A1
miRNA for FAM91A1 Gene
- miRTarBase miRNAs that target FAM91A1
-
- hsa-mir-155-5p (MIRT020920)
- hsa-mir-106b-5p (MIRT044344)
- hsa-mir-125b-5p (MIRT046033)
- hsa-mir-30a-5p (MIRT105029)
- hsa-mir-30c-5p (MIRT105030)
- hsa-mir-30d-5p (MIRT105031)
- hsa-mir-30b-5p (MIRT105033)
- hsa-mir-30e-5p (MIRT105036)
- hsa-mir-32-5p (MIRT172277)
- hsa-mir-92a-3p (MIRT172278)
- hsa-mir-92b-3p (MIRT172288)
- hsa-mir-548e-5p (MIRT172299)
- hsa-mir-595 (MIRT224272)
- hsa-mir-1910-3p (MIRT224273)
- hsa-mir-3658 (MIRT224275)
- hsa-mir-3714 (MIRT224276)
- hsa-mir-548an (MIRT224278)
- hsa-mir-6511a-5p (MIRT224280)
- hsa-mir-3653-3p (MIRT499591)
- hsa-mir-6885-3p (MIRT723226)
- hsa-mir-4639-5p (MIRT723227)
- hsa-mir-23c (MIRT723228)
- hsa-mir-23b-3p (MIRT723229)
- hsa-mir-23a-3p (MIRT723230)
- hsa-mir-130a-5p (MIRT723231)
- hsa-mir-520f-5p (MIRT723232)
- hsa-mir-6796-3p (MIRT723233)
- hsa-mir-548c-3p (MIRT723234)
miRNA Products
- Search ViGene Biosciences for FAM91A1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM91A1
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-
ViGene Biosciences ready-to-package AAV shRNAs for FAM91A1 gene
Clone Products
-
OriGene ORF clones in human for FAM91A1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM91A1
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM91A1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM91A1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM91A1 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM91A1 Gene
Localization for FAM91A1 Gene
| Compartment | Confidence |
|---|---|
| cytoskeleton | 2 |
| nucleus | 2 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM91A1 Gene
Pathways & Interactions for FAM91A1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Gastric Cancer Network 2 | ||
Pathways by source for FAM91A1 Gene
1 BioSystems pathway for FAM91A1 Gene
No data available for SIGNOR curated interactions for FAM91A1 Gene
Transcripts for FAM91A1 Gene
mRNA/cDNA for FAM91A1 Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (228) Selected AceView cDNA sequences:
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM91A1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM91A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM91A1
- GenScript: Design CRISPR guide RNA sequences for FAM91A1
miRNA Products
- Search ViGene Biosciences for FAM91A1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM91A1
- Browse OriGene Inhibitory RNA Products For FAM91A1
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM91A1 gene
Clone Products
-
OriGene ORF clones in human for FAM91A1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM91A1 Gene
This gene is overexpressed in Peripheral blood mononuclear cells (18.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM91A1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FAM91A1 Gene:
FAM91A1SOURCE GeneReport for Unigene cluster for FAM91A1 Gene:
Hs.459174Evidence on tissue expression from TISSUES for FAM91A1 Gene
- Nervous system(3.8)
Primer Products
-
OriGene qPCR primer pairs for FAM91A1
-
OriGene qPCR primer pairs and template standards for FAM91A1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM91A1 Gene
Orthologs for FAM91A1 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM91A1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM91A1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM91A1 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM91A1 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | FAM91A1 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Fam91a1 34 |
|
||
| mouse (Mus musculus) |
Mammalia | D15Ertd621e 34 35 |
|
||
| Fam91a1 16 |
|
||||
| chicken (Gallus gallus) |
Aves | FAM91A1 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FAM91A1 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam91a1 34 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.8925 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fam91a1 34 35 |
|
||
| zgc63609 34 |
|
||||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002874 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG7600 34 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | F33H2.2 34 35 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | AT1G35220 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os01g0303200 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany |
- Species where no ortholog for FAM91A1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for FAM91A1 Gene
(1) SIMAP similar genes for FAM91A1 Gene using alignment to 6 proteins:
Pseudogenes.org Pseudogenes for FAM91A1 Gene
No data available for Paralogs for FAM91A1 Gene
Variants for FAM91A1 Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000056789 | -- | 123,789,965(+) | TATTT(A/G)AATCT | intron-variant | |
| rs1000099054 | -- | 123,803,875(+) | AATGT(A/G)TGGGT | intron-variant | |
| rs1000225854 | -- | 123,784,305(+) | GTGTA(C/T)GTATT | intron-variant | |
| rs1000274495 | -- | 123,791,785(+) | AGAGG(A/G)TATCT | intron-variant | |
| rs1000355926 | -- | 123,766,579(+) | ATCCA(C/G)ATAGC | downstream-variant-500B, upstream-variant-2KB |
Residual Variation Intolerance Score:
16.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.47;
28.78% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM91A1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM91A1 Gene
Disorders for FAM91A1 Gene
Relevant External Links for FAM91A1
No disorders were found for FAM91A1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM91A1 Gene
Publications for FAM91A1 Gene
- A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. (PMID: 19734545) Need A.C. … Goldstein D.B. (Hum. Mol. Genet. 2009) 3 46 64
- DNA sequence and analysis of human chromosome 8. (PMID: 16421571) Nusbaum C. … Lander E.S. (Nature 2006) 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3 64
Products for FAM91A1 Gene
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- OriGene qPCR primer pairs and template standards for FAM91A1
- OriGene qPCR primer pairs for FAM91A1
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- Novus Biologicals Antibodies for FAM91A1
- Novus Biologicals proteins for FAM91A1
- Novus Biologicals
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- VectorBuilder custom plasmid, inducible vectors for FAM91A1
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM91A1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer