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Aliases for FAM91A1 Gene

Aliases for FAM91A1 Gene

  • Family With Sequence Similarity 91, Member A1 2 3

External Ids for FAM91A1 Gene

Previous GeneCards Identifiers for FAM91A1 Gene

  • GC08P124860
  • GC08P120107
  • GC08P124780

Summaries for FAM91A1 Gene

GeneCards Summary for FAM91A1 Gene

FAM91A1 (Family With Sequence Similarity 91, Member A1) is a Protein Coding gene. Among its related pathways are Gastric cancer network 2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM91A1 Gene

Genomics for FAM91A1 Gene

Regulatory Elements for FAM91A1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM91A1 Gene

123,768,439 bp from pter
123,815,452 bp from pter
47,014 bases
Plus strand

Genomic View for FAM91A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM91A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM91A1 Gene

Proteins for FAM91A1 Gene

  • Protein details for FAM91A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM91A1
    Protein Accession:
    Secondary Accessions:
    • B6YY23
    • Q658T5
    • Q8TE89

    Protein attributes for FAM91A1 Gene

    838 amino acids
    Molecular mass:
    93909 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB85063.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FAM91A1 Gene

Proteomics data for FAM91A1 Gene at MOPED

Post-translational modifications for FAM91A1 Gene

  • Ubiquitination at Lys 638
  • Modification sites at PhosphoSitePlus

Other Protein References for FAM91A1 Gene

Antibody Products

No data available for DME Specific Peptides for FAM91A1 Gene

Domains & Families for FAM91A1 Gene

Protein Domains for FAM91A1 Gene


Suggested Antigen Peptide Sequences for FAM91A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM91 family.
  • Belongs to the FAM91 family.
genes like me logo Genes that share domains with FAM91A1: view

No data available for Gene Families for FAM91A1 Gene

Function for FAM91A1 Gene

Phenotypes for FAM91A1 Gene

GenomeRNAi human phenotypes for FAM91A1:
genes like me logo Genes that share phenotypes with FAM91A1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM91A1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM91A1 Gene

Localization for FAM91A1 Gene

Subcellular locations from

Jensen Localization Image for FAM91A1 Gene COMPARTMENTS Subcellular localization image for FAM91A1 gene
Compartment Confidence
cytoskeleton 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM91A1 Gene

Pathways & Interactions for FAM91A1 Gene

SuperPathways for FAM91A1 Gene

Superpath Contained pathways
1 Gastric cancer network 2
genes like me logo Genes that share pathways with FAM91A1: view

Pathways by source for FAM91A1 Gene

1 BioSystems pathway for FAM91A1 Gene

Interacting Proteins for FAM91A1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: Q658Y4-F91A1_HUMAN ENSP00000335082 for FAM91A1 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for FAM91A1 Gene


No data available for SIGNOR curated interactions for FAM91A1 Gene

Drugs & Compounds for FAM91A1 Gene

No Compound Related Data Available

Transcripts for FAM91A1 Gene

Unigene Clusters for FAM91A1 Gene

Family with sequence similarity 91, member A1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM91A1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM91A1 Gene

No ASD Table

Relevant External Links for FAM91A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM91A1 Gene

mRNA expression in normal human tissues for FAM91A1 Gene

Protein differential expression in normal tissues from HIPED for FAM91A1 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (18.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM91A1 Gene

SOURCE GeneReport for Unigene cluster for FAM91A1 Gene Hs.459174

genes like me logo Genes that share expression patterns with FAM91A1: view

Protein tissue co-expression partners for FAM91A1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM91A1 Gene

Orthologs for FAM91A1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for FAM91A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM91A1 35
  • 91.73 (n)
  • 95.7 (a)
FAM91A1 36
  • 95 (a)
(Canis familiaris)
Mammalia FAM91A1 35
  • 93 (n)
  • 96.54 (a)
FAM91A1 36
  • 95 (a)
(Mus musculus)
Mammalia D15Ertd621e 35
  • 88.73 (n)
  • 94.98 (a)
D15Ertd621e 16
D15Ertd621e 36
  • 95 (a)
(Pan troglodytes)
Mammalia FAM91A1 35
  • 99.72 (n)
  • 99.88 (a)
FAM91A1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam91a1 35
  • 89.5 (n)
  • 94.51 (a)
(Monodelphis domestica)
Mammalia FAM91A1 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia FAM91A1 36
  • 91 (a)
(Gallus gallus)
Aves FAM91A1 35
  • 81.63 (n)
  • 88.96 (a)
FAM91A1 36
  • 88 (a)
(Anolis carolinensis)
Reptilia FAM91A1 36
  • 87 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam91a1 35
  • 75.64 (n)
  • 85.46 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8925 35
(Danio rerio)
Actinopterygii fam91a1 35
  • 71.42 (n)
  • 79.9 (a)
zgc63609 35
fam91a1 36
  • 79 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002874 35
  • 48.97 (n)
  • 42.67 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG7600 35
  • 48.62 (n)
  • 44.59 (a)
CG7600 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea F33H2.2 35
  • 52.09 (n)
  • 47.32 (a)
F33H2.2 36
  • 40 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT1G35220 35
  • 48.63 (n)
  • 37.97 (a)
(Oryza sativa)
Liliopsida Os01g0303200 35
  • 49.26 (n)
  • 39.29 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 34 (a)
-- 36
  • 57 (a)
Species with no ortholog for FAM91A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM91A1 Gene

Gene Tree for FAM91A1 (if available)
Gene Tree for FAM91A1 (if available)

Paralogs for FAM91A1 Gene

(1) SIMAP similar genes for FAM91A1 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with FAM91A1: view

No data available for Paralogs for FAM91A1 Gene

Variants for FAM91A1 Gene

Sequence variations from dbSNP and Humsavar for FAM91A1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1045923 -- 123,814,599(+) ATCAT(G/T)AATTT utr-variant-3-prime
rs1367826 -- 123,809,296(+) ATGCT(C/G)ATATG intron-variant
rs1367829 -- 123,784,895(+) ACTCC(A/G)TGGAT intron-variant
rs1541876 -- 123,773,800(+) TGAAG(C/T)TACAC intron-variant
rs1801533 -- 123,815,220(+) TTTAC(C/T)TGTTG utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for FAM91A1 Gene

Variant ID Type Subtype PubMed ID
nsv831451 CNV Gain+Loss 17160897
nsv6373 CNV Loss 18451855

Variation tolerance for FAM91A1 Gene

Residual Variation Intolerance Score: 16.91% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.47; 28.78% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM91A1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM91A1 Gene

Disorders for FAM91A1 Gene

Relevant External Links for FAM91A1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM91A1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM91A1 Gene

Publications for FAM91A1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation. (PMID: 25921289) Emdal K.B. … Olsen J.V. (Sci Signal 2015) 67
  4. Quantitative Lys-I/-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. (PMID: 25147182) Thompson J.W. … Luchansky S.J. (J. Biol. Chem. 2014) 67
  5. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 67

Products for FAM91A1 Gene

Sources for FAM91A1 Gene

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