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Aliases for FAM90A1 Gene

Aliases for FAM90A1 Gene

  • Family With Sequence Similarity 90, Member A1 2 3

External Ids for FAM90A1 Gene

Previous GeneCards Identifiers for FAM90A1 Gene

  • GC12M008266
  • GC12M008373

Summaries for FAM90A1 Gene

Entrez Gene Summary for FAM90A1 Gene

  • FAM90A1 belongs to subfamily I of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]).[supplied by OMIM, Oct 2009]

GeneCards Summary for FAM90A1 Gene

FAM90A1 (Family With Sequence Similarity 90, Member A1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is FAM90A26.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM90A1 Gene

Genomics for FAM90A1 Gene

Regulatory Elements for FAM90A1 Gene

Genomic Location for FAM90A1 Gene

8,221,260 bp from pter
8,227,703 bp from pter
6,444 bases
Minus strand

Genomic View for FAM90A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM90A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM90A1 Gene

Proteins for FAM90A1 Gene

  • Protein details for FAM90A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM90A1
    Protein Accession:
    Secondary Accessions:
    • D3DUU9
    • Q9NVZ6

    Protein attributes for FAM90A1 Gene

    464 amino acids
    Molecular mass:
    49793 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM90A1 Gene

Proteomics data for FAM90A1 Gene at MOPED

Post-translational modifications for FAM90A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM90A1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for FAM90A1 Gene

Domains & Families for FAM90A1 Gene

Protein Domains for FAM90A1 Gene


Suggested Antigen Peptide Sequences for FAM90A1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM90 family.
  • Belongs to the FAM90 family.
genes like me logo Genes that share domains with FAM90A1: view

No data available for Gene Families for FAM90A1 Gene

Function for FAM90A1 Gene

Gene Ontology (GO) - Molecular Function for FAM90A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 21516116
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with FAM90A1: view

Phenotypes for FAM90A1 Gene

GenomeRNAi human phenotypes for FAM90A1:
genes like me logo Genes that share phenotypes with FAM90A1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM90A1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM90A1 Gene

Localization for FAM90A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM90A1 Gene

Pathways & Interactions for FAM90A1 Gene

SuperPathways for FAM90A1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM90A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM90A1 Gene

Drugs & Compounds for FAM90A1 Gene

No Compound Related Data Available

Transcripts for FAM90A1 Gene

mRNA/cDNA for FAM90A1 Gene

(5) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM90A1 Gene

Family with sequence similarity 90, member A1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM90A1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM90A1 Gene

No ASD Table

Relevant External Links for FAM90A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM90A1 Gene

mRNA expression in normal human tissues for FAM90A1 Gene

Protein differential expression in normal tissues from HIPED for FAM90A1 Gene

This gene is overexpressed in Heart (38.1) and Platelet (30.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM90A1 Gene

SOURCE GeneReport for Unigene cluster for FAM90A1 Gene Hs.196086

genes like me logo Genes that share expression patterns with FAM90A1: view

Protein tissue co-expression partners for FAM90A1 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM90A1 Gene

Orthologs for FAM90A1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM90A1 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia 4932442L08Rik 35
  • 53.06 (n)
  • 35.46 (a)
C86695 16
4932442L08Rik 36
  • 31 (a)
C86695 36
  • 26 (a)
(Pan troglodytes)
Mammalia FAM90A1 35
  • 98.28 (n)
  • 96.55 (a)
FAM90A1 36
  • 96 (a)
(Rattus norvegicus)
Mammalia LOC102554431 35
  • 53.95 (n)
  • 35.82 (a)
(Bos Taurus)
Mammalia -- 36
  • 33 (a)
-- 36
  • 32 (a)
(Canis familiaris)
Mammalia -- 36
  • 34 (a)
-- 36
  • 35 (a)
-- 36
  • 34 (a)
-- 36
  • 33 (a)
Species with no ortholog for FAM90A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM90A1 Gene

Gene Tree for FAM90A1 (if available)
Gene Tree for FAM90A1 (if available)

Paralogs for FAM90A1 Gene

Paralogs for FAM90A1 Gene

genes like me logo Genes that share paralogs with FAM90A1: view

Variants for FAM90A1 Gene

Sequence variations from dbSNP and Humsavar for FAM90A1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs2004352 -- 8,226,945(-) ACCTG(C/T)AGTCC intron-variant
rs2077467 -- 8,226,339(+) CCTTG(A/T)CATGC utr-variant-5-prime, upstream-variant-2KB, intron-variant
rs2902723 -- 8,228,553(-) accct(A/G)tctct upstream-variant-2KB
rs77978823 -- 8,222,067(+) GCTGG(C/T)CGCTG missense, reference
rs77334570 -- 8,225,200(+) CACTC(C/T)GGTAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM90A1 Gene

Variant ID Type Subtype PubMed ID
dgv455e1 CNV Complex 17122850
nsv428270 CNV Gain 18775914
dgv459e1 CNV Complex 17122850
dgv460e1 CNV Complex 17122850
dgv461e1 CNV Complex 17122850
nsv8899 CNV Gain+Loss 18304495
esv29886 CNV Gain+Loss 19812545
dgv462e1 CNV Complex 17122850
nsv826226 CNV Gain 20364138
dgv463e1 CNV Complex 17122850
essv6083 CNV CNV 17122850
essv1083 CNV CNV 17122850
nsv433419 CNV Gain 18776910
dgv1365n71 CNV Gain 21882294
nsv820442 CNV Duplication 20802225
dgv464e1 CNV Complex 17122850
dgv465e1 CNV Complex 17122850
esv995004 CNV Gain 20482838
nsv514677 CNV Complex 21397061
esv1001803 CNV Insertion 20482838
essv13388 CNV CNV 17122850
esv2523633 CNV Loss 19546169

Variation tolerance for FAM90A1 Gene

Residual Variation Intolerance Score: 96.75% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.91; 96.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM90A1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM90A1 Gene

Disorders for FAM90A1 Gene

Relevant External Links for FAM90A1

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM90A1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM90A1 Gene

Publications for FAM90A1 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 67
  4. LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (PMID: 23443559) Fogeron M.L. … Lange B.M. (Nat Commun 2013) 67
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 67

Products for FAM90A1 Gene

Sources for FAM90A1 Gene

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