Aliases for FAM90A1 Gene
Aliases for FAM90A1 Gene
External Ids for FAM90A1 Gene
- HGNC: 25526
- Entrez Gene: 55138
- Ensembl: ENSG00000171847
- OMIM: 613041
- UniProtKB: Q86YD7
Previous GeneCards Identifiers for FAM90A1 Gene
- GC12M008266
- GC12M008373
Summaries for FAM90A1 Gene
-
FAM90A1 belongs to subfamily I of the primate-specific FAM90A gene family, which originated from multiple duplications and rearrangements (Bosch et al., 2007 [PubMed 17684299]).[supplied by OMIM, Oct 2009]
GeneCards Summary for FAM90A1 Gene
FAM90A1 (Family With Sequence Similarity 90 Member A1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is FAM90A26.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM90A1 Gene
Genomics for FAM90A1 Gene
Regulatory Elements for FAM90A1 Gene
- Transcription factor binding sites by QIAGEN in the FAM90A1 gene promoter:
Regulatory Element Products
Genomic Location for FAM90A1 Gene
- Chromosome:
- 12
- Start:
- 8,221,260 bp from pter
- End:
- 8,227,703 bp from pter
- Size:
- 6,444 bases
- Orientation:
- Minus strand
Genomic View for FAM90A1 Gene
Genes around FAM90A1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.31 by Ensembl
- 12p13.31 by Entrez Gene
- 12p13.31 by HGNC
FAM90A1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM90A1 Gene
Proteins for FAM90A1 Gene
-
Protein details for FAM90A1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q86YD7-F90A1_HUMAN
- Recommended name:
- Protein FAM90A1
- Protein Accession:
- Q86YD7
- D3DUU9
- Q9NVZ6
Protein attributes for FAM90A1 Gene
- Size:
- 464 amino acids
- Molecular mass:
- 49793 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM90A1 Gene
Post-translational modifications for FAM90A1 Gene
Other Protein References for FAM90A1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FAM90A1
- Novus Biologicals Antibodies for FAM90A1
-
Abcam antibodies for FAM90A1
- Invitrogen Antibodies for FAM90A1
- antibodies-online Antibodies for FAM90A1: See all 7
- GeneTex FAM90A1 antibody for FAM90A1
-
Santa Cruz Biotechnology (SCBT) Antibodies for FAM90A1
Protein Products
-
OriGene Purified Proteins for FAM90A1
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- Search GeneTex for Proteins for FAM90A1
Assay Products
No data available for DME Specific Peptides for FAM90A1 Gene
Domains & Families for FAM90A1 Gene
Protein Domains for FAM90A1 Gene
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for FAM90A1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q86YD7- Family:
-
- Belongs to the FAM90 family.
No data available for Gene Families for FAM90A1 Gene
Function for FAM90A1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 21516116 |
Phenotypes for FAM90A1 Gene
- GenomeRNAi human phenotypes for FAM90A1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM90A1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM90A1 gene
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CRISPR Products
-
OriGene CRISPR knockouts for FAM90A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM90A1
- GenScript: Design CRISPR guide RNA sequences for FAM90A1
miRNA Products
- Search ViGene Biosciences for FAM90A1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM90A1
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-
ViGene Biosciences ready-to-package AAV shRNAs for FAM90A1 gene
Clone Products
-
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Cell Line Products
-
Horizon Cell Lines for FAM90A1
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM90A1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM90A1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM90A1 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM90A1 Gene
Localization for FAM90A1 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM90A1 Gene
Pathways & Interactions for FAM90A1 Gene
No Data Available
Interacting Proteins for FAM90A1 Gene
Selected Interacting proteins:
Q86YD7-F90A1_HUMAN
ENSP00000307798
for FAM90A1 Gene via
IID
UniProtKB
STRING
MINT
No data available for Pathways by source and SIGNOR curated interactions for FAM90A1 Gene
Transcripts for FAM90A1 Gene
mRNA/cDNA for FAM90A1 Gene
- (5) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (13) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM90A1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM90A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM90A1
- GenScript: Design CRISPR guide RNA sequences for FAM90A1
miRNA Products
- Search ViGene Biosciences for FAM90A1
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM90A1
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-
ViGene Biosciences ready-to-package AAV shRNAs for FAM90A1 gene
Clone Products
-
OriGene ORF clones in human for FAM90A1
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Flow Cytometry Products
Expression for FAM90A1 Gene
This gene is overexpressed in Heart (38.1) and Platelet (30.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM90A1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FAM90A1 Gene:
FAM90A1SOURCE GeneReport for Unigene cluster for FAM90A1 Gene:
Hs.196086Primer Products
-
OriGene qPCR primer pairs for FAM90A1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM90A1 Gene
Orthologs for FAM90A1 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM90A1 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | LOC102554431 34 |
|
||
| mouse (Mus musculus) |
Mammalia | 4932442L08Rik 34 35 |
|
||
| C86695 35 |
|
ManyToMany | |||
| Fam90a1b 16 |
|
||||
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| cow (Bos Taurus) |
Mammalia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany |
- Species where no ortholog for FAM90A1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM90A1 Gene
(19) SIMAP similar genes for FAM90A1 Gene using alignment to 2 proteins:
Pseudogenes.org Pseudogenes for FAM90A1 Gene
Variants for FAM90A1 Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000549683 | -- | 8,224,086(+) | CTTCC(A/G)TGGTT | reference, missense | |
| rs1002502413 | -- | 8,228,146(+) | CACTG(C/T)TGCCC | upstream-variant-2KB | |
| rs1002784176 | -- | 8,227,800(+) | TCCAG(G/T)TCTGC | upstream-variant-2KB | |
| rs1003511059 | -- | 8,226,576(+) | CCAGG(A/G)AGGGG | intron-variant, upstream-variant-2KB | |
| rs1003794091 | -- | 8,226,249(+) | GTTTT(A/T)AAAAA | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1358n100 | CNV | gain | 25217958 |
| dgv1359n100 | CNV | gain | 25217958 |
| dgv1360n100 | CNV | gain | 25217958 |
| dgv2339n54 | CNV | gain | 21841781 |
| dgv2340n54 | CNV | loss | 21841781 |
| dgv247e214 | CNV | gain | 21293372 |
| esv1001803 | CNV | insertion | 20482838 |
| esv2523633 | CNV | loss | 19546169 |
| esv2759877 | CNV | gain+loss | 17122850 |
| esv2760237 | CNV | gain | 21179565 |
| esv2760766 | CNV | gain | 21179565 |
| esv2871568 | CNV | duplication | 24192839 |
| esv29886 | CNV | gain+loss | 19812545 |
| esv995004 | CNV | gain | 20482838 |
| nsv1159957 | CNV | duplication | 26073780 |
| nsv1159958 | CNV | duplication | 26073780 |
| nsv428270 | CNV | gain | 18775914 |
| nsv433419 | CNV | gain | 18776910 |
| nsv514677 | CNV | gain | 21397061 |
| nsv557336 | CNV | loss | 21841781 |
| nsv557337 | CNV | loss | 21841781 |
| nsv557338 | CNV | gain | 21841781 |
| nsv557339 | CNV | loss | 21841781 |
| nsv820442 | CNV | duplication | 20802225 |
| nsv826226 | CNV | gain | 20364138 |
| nsv8899 | CNV | gain+loss | 18304495 |
| nsv952794 | CNV | deletion | 24416366 |
| nsv973015 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
96.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
14.91;
96.77% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM90A1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM90A1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM90A1 Gene
Disorders for FAM90A1 Gene
Relevant External Links for FAM90A1
No disorders were found for FAM90A1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM90A1 Gene
Publications for FAM90A1 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- Pooled-matrix protein interaction screens using Barcode Fusion Genetics. (PMID: 27107012) Yachie N. … Roth F.P. (Mol. Syst. Biol. 2016) 3 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
- LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. (PMID: 23443559) Fogeron M.L. … Lange B.M. (Nat Commun 2013) 3 64
Products for FAM90A1 Gene
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- VectorBuilder custom plasmid, inducible vectors for FAM90A1
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- Mammalian expression: PiggyBac
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- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM90A1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
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- (122) diseasecard
- (123) NIH Rare Diseases
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- (127) Disease Ontology
- (128) Genetics Home Reference
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- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer