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Aliases for FAM8A1 Gene

Aliases for FAM8A1 Gene

  • Family With Sequence Similarity 8, Member A1 2 3
  • Autosomal Highly Conserved Protein 3 4
  • AHCP 3 4
  • Protein FAM8A1 3

External Ids for FAM8A1 Gene

Summaries for FAM8A1 Gene

GeneCards Summary for FAM8A1 Gene

FAM8A1 (Family With Sequence Similarity 8, Member A1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM8A1 Gene

Genomics for FAM8A1 Gene

Genomic Location for FAM8A1 Gene

Start:
17,600,287 bp from pter
End:
17,611,719 bp from pter
Size:
11,433 bases
Orientation:
Plus strand

Genomic View for FAM8A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM8A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM8A1 Gene

Regulatory Elements for FAM8A1 Gene

Proteins for FAM8A1 Gene

  • Protein details for FAM8A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UBU6-FA8A1_HUMAN
    Recommended name:
    Protein FAM8A1
    Protein Accession:
    Q9UBU6
    Secondary Accessions:
    • B2R725

    Protein attributes for FAM8A1 Gene

    Size:
    413 amino acids
    Molecular mass:
    44123 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM8A1 Gene

Proteomics data for FAM8A1 Gene at MOPED

Post-translational modifications for FAM8A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM8A1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM8A1 Gene

Domains for FAM8A1 Gene

Protein Domains for FAM8A1 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

FA8A1_HUMAN
Domain:
  • Contains 1 RDD domain.:
    • Q9UBU6
genes like me logo Genes that share domains with FAM8A1: view

No data available for Gene Families for FAM8A1 Gene

Function for FAM8A1 Gene

miRNA for FAM8A1 Gene

miRTarBase miRNAs that target FAM8A1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM8A1 Gene

Localization for FAM8A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM8A1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM8A1 Gene COMPARTMENTS Subcellular localization image for FAM8A1 gene
Compartment Confidence
plasma membrane 3
endoplasmic reticulum 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM8A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM8A1: view

Pathways for FAM8A1 Gene

SuperPathways for FAM8A1 Gene

No Data Available

Interacting Proteins for FAM8A1 Gene

Gene Ontology (GO) - Biological Process for FAM8A1 Gene

None

No data available for Pathways by source for FAM8A1 Gene

Transcripts for FAM8A1 Gene

mRNA/cDNA for FAM8A1 Gene

(1) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(182) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM8A1 Gene

Family with sequence similarity 8, member A1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM8A1 Gene

No ASD Table

Relevant External Links for FAM8A1 Gene

GeneLoc Exon Structure for
FAM8A1
ECgene alternative splicing isoforms for
FAM8A1

Expression for FAM8A1 Gene

mRNA expression in normal human tissues for FAM8A1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM8A1 Gene

SOURCE GeneReport for Unigene cluster for FAM8A1 Gene Hs.95260

mRNA Expression by UniProt/SwissProt for FAM8A1 Gene

Q9UBU6-FA8A1_HUMAN
Tissue specificity: Ubiquitously expressed, with a higher level of expression in testis.
genes like me logo Genes that share expressions with FAM8A1: view

Orthologs for FAM8A1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM8A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM8A1 36
  • 99.51 (n)
  • 99.51 (a)
FAM8A1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM8A1 36
  • 87.19 (n)
  • 82.48 (a)
FAM8A1 37
  • 82 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM8A1 36
  • 85.08 (n)
  • 79.58 (a)
FAM8A1 37
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia C78339 36
  • 82.65 (n)
  • 81.12 (a)
C78339 16
C78339 37
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM8A1 37
  • 59 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM8A1 37
  • 65 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam8a1 36
  • 84.51 (n)
  • 82.51 (a)
chicken
(Gallus gallus)
Aves FAM8A1 36
  • 73.14 (n)
  • 74.67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam8a1 36
  • 67.51 (n)
  • 68.23 (a)
zebrafish
(Danio rerio)
Actinopterygii -- 36
fam8a1 37
  • 49 (a)
OneToMany
FAM8A1 (2 of 3) 37
  • 54 (a)
OneToMany
FAM8A1 (3 of 3) 37
  • 54 (a)
OneToMany
LOC100537042 36
  • 61.82 (n)
  • 58.16 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8237 37
  • 24 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 31 (a)
OneToOne
Species with no ortholog for FAM8A1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM8A1 Gene

ENSEMBL:
Gene Tree for FAM8A1 (if available)
TreeFam:
Gene Tree for FAM8A1 (if available)

Paralogs for FAM8A1 Gene

genes like me logo Genes that share paralogs with FAM8A1: view

No data available for Paralogs for FAM8A1 Gene

Variants for FAM8A1 Gene

Sequence variations from dbSNP and Humsavar for FAM8A1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1012470 -- 17,607,405(-) gaggt(G/T)gttag intron-variant
rs1055111 -- 17,609,859(+) TTTCT(G/T)TGACG utr-variant-3-prime
rs1063675 -- 17,611,071(+) CCAAC(G/T)GAACT utr-variant-3-prime
rs1969598 -- 17,600,856(+) CCGCA(A/G)AGCTT synonymous-codon, reference
rs1969830 -- 17,606,182(+) CAGTA(C/T)ACATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM8A1 Gene

Variant ID Type Subtype PubMed ID
nsv516012 CNV Gain+Loss 19592680
nsv883455 CNV Gain 21882294
nsv883456 CNV Gain 21882294
nsv883457 CNV Gain 21882294
nsv883458 CNV Gain 21882294
nsv830596 CNV Gain 17160897
esv2731633 CNV Deletion 23290073

Relevant External Links for FAM8A1 Gene

HapMap Linkage Disequilibrium report
FAM8A1
Human Gene Mutation Database (HGMD)
FAM8A1

Disorders for FAM8A1 Gene

No disorders were found for FAM8A1 Gene.

No data available for UniProtKB/Swiss-Prot for FAM8A1 Gene

Publications for FAM8A1 Gene

  1. Transduction of the human gene FAM8A1 by endogenous retrovirus during primate evolution. (PMID: 11707071) Jamain S. … Bourgeron T. (Genomics 2001) 2 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  3. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PMID: 15144186) Brill L.M. … Peters E.C. (Anal. Chem. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for FAM8A1 Gene

Sources for FAM8A1 Gene

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