FAM86C1 Gene
protein-coding GIFtS: 38
GCID: GC11P071500
|
|
family with sequence similarity 86, member C1(Previous names: family with sequence similarity 86, member C )
(Previous symbol: FAM86C)
| |
Aliases
for FAM86C1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Family With Sequence Similarity 86, Member C11 2 | | FLJ271991 | | FAM86C1 2 3 | | Protein FAM86C12 | | Family With Sequence Similarity 86, Member C1 2 | | Protein FAM86C3 | | FLJ106611 | | |
| External Ids: | HGNC: 255611 | Entrez Gene: 551992 | Ensembl: ENSG000001584837 | UniProtKB: Q9NVL13 | | ORGUL members: | |
|---|
| NONCODE:n342775 | |
Export aliases for FAM86C1 gene to outside databases
|---|
Summaries
for FAM86C1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM86C1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM86C1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM86C1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM86C1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q13.4 Ensembl cytogenetic band: 11q13.4 HGNC cytogenetic band: 11q13.4FAM86C1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P071500: view genomic region
(about GC identifiers)
Start:
|
71,498,556 bp from pter |
End:
|
71,512,282 bp from pter |
Size:
|
13,727 bases |
Orientation:
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plus strand |
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Proteins
for FAM86C1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FA86C_HUMAN, Q9NVL1 (See
protein sequence)Recommended Name: Protein FAM86C1 Size: 165 amino acids; 18454 Da
Secondary accessions: Q8N5D3Alternative splicing: 3 isoforms: Q9NVL1-1 Q9NVL1-2 Q9NVL1-3 Explore the universe of human proteins at neXtProt for FAM86C1: NX_Q9NVL1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NVL1
FAM86C1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001093123.1 NP_060642.2 NP_689776.1
ENSEMBL proteins: ENSP00000325662 ENSP00000432416 ENSP00000423511 ENSP00000352182 ENSP00000391329 ENSP00000436598
Human Recombinant Protein Products:
FAM86C1 Antibody Products:
Assay Products for FAM86C1: |
Protein
Domains /
Families
for FAM86C1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9NVL1 UniProtKB/Swiss-Prot: FA86C_HUMAN, Q9NVL1Similarity: Belongs to the FAM86 family |
Function
for FAM86C1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86C1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86C1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for FAM86C1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM86C1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM86C1 |
|
Pathways & Interactions
for FAM86C1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM86C1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for FAM86C1 (Q9NVL12, 3 ENSP000003521824) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for FAM86C1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM86C1
Search CenterWatch for drugs/clinical trials and news about FAM86C1 / FA86C
|
Transcripts
for FAM86C1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM86C1 gene (3 alternative transcripts): NM_001099653.1 NM_018172.2 NM_152563.2 Unigene Cluster for FAM86C1: Family with sequence similarity 86, member C1 Hs.567527 [show with all ESTs]Unigene Representative Sequence: NM_0181726 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000346333(uc009ysr.3 uc001oqw.4 uc009yss.3 uc010rqq.2)
ENST00000526393 ENST00000510443 ENST00000359244(uc001oqv.4) ENST00000426628
ENST00000528685
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86C1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86C1 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for FAM86C1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM86C1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM86C1 |
Additional cDNA sequence: AK001523.1 AK130709.1 AK293221.1 AK311428.1 AK311518.1 AK311675.1 AK315454.1 BC032519.1 8 DOTS entries: DT.100039028 DT.86994913 DT.100039034 DT.120705994 DT.95277946 DT.100802969 DT.40109072 DT.91969689 24/42 AceView cDNA sequences (see all 42): BQ921333 BU160080 BM451472 BM793838 BU179083 AK130709 BM797131 BQ960450 BU528509 NM_018172 BX641967 NM_152563 BX641966 BC032519 AI591187 BU528060 AU129712 BG747631 AK001523 BU682159 BV203269 AW976018 AA235236 CF142111
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM86C1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b |
|---|
|
| SP1: | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM86C1
|
Expression
for FAM86C1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM86C1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM86C1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM86C1
SOURCE GeneReport for Unigene cluster: Hs.567527
SABiosciences Custom PCR Arrays for FAM86C1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM86C1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM86C1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM86C1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM86C1 |
Orthologs
for FAM86C1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM86C1 gene from 7/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LOC4163926 |
hypothetical protein LOC416392 |
18(a) |
1 → many |
14(14150470-14154909) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
16(a) |
1 → many |
GL343402.1(678506-686747) |
zebrafish
(Danio rerio) |
Actinopterygii |
fam86a6 |
family with sequence similarity 86, member A |
15(a) |
1 → many |
3(29020729-29023875) |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG78896 |
-- |
8(a) |
1 → many |
X(19137666-19139255) |
worm
(Caenorhabditis elegans) |
Secernentea |
R08D7.46 |
Uncharacterized protein R08D7.4 |
8(a) |
1 → many |
III(8971815-8973872) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G274006 |
S-adenosyl-L-methionine-dependent methyltransferas... |
8(a) |
1 → many |
5(9676334-9678503) |
rice
(Oryza sativa) |
Liliopsida |
-- |
GA20663-PA, putative, expressed |
5(a) |
1 → many |
5(2494958-2499418) |
ENSEMBL Gene Tree for FAM86C1 (if available)
TreeFam Gene Tree for FAM86C1 (if available) |
Paralogs
for FAM86C1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM86C1 gene
- FAM86A2 FAM86B12 FAM86B22
4 SIMAP similar genes for FAM86C1 using alignment to 3 protein entries: FA86C_HUMAN (see all proteins):FAM86A FAM86B1 FAM86C2P FAM86B2
FAM86C1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for FAM86C1
PGOHUM00000250300 PGOHUM00000258226
|
Genomic Variants
for FAM86C1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM86C1 (71498556 - 71512282 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM86C1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM86C1 |
|
Disorders
/ Diseases
for FAM86C1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM86C1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM86C1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM86C1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for FAM86C1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM86C1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM86C1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM86C1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM86C1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM86C1 gene:
Search GeneIP for patents involving FAM86C1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM86C1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM86C1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM86C1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM86C1 | | | OriGene Protein Over-expression Lysate for FAM86C1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM86C1 | | OriGene 3'-UTR Clone for FAM86C1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86C1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86C1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM86C1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM86C1 | | OriGene Custom Protein Services for FAM86C1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM86C1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM86C1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM86C1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM86C1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM86C1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM86C1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for FAM86C1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | FAM86C1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for FAM86C1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM86C1 |
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