FAM86A Gene
protein-coding GIFtS: 44
GCID: GC16M005134
|
|
family with sequence similarity 86, member A
| |
Aliases
for FAM86A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 86, Member A1 2 | | MGC196361 | | SB1531 | | Protein FAM86A2 |
Export aliases for FAM86A gene to outside databasesPrevious GC identifer: GC16M005076 |
Summaries
for FAM86A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM86A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010393.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM86A gene promoter:
HOXA9B HOXA9 AML1a NRSF form 1 AP-4 LCR-F1 NRSF form 2 RORalpha1 STAT3 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM86A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM86A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16p13.3 Ensembl cytogenetic band: 16p13.3 HGNC cytogenetic band: 16p13.3FAM86A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16M005134: view genomic region
(about GC identifiers)
Start:
|
5,134,301 bp from pter |
End:
|
5,147,809 bp from pter |
Size:
|
13,509 bases |
Orientation:
|
minus strand |
|
Proteins
for FAM86A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FA86A_HUMAN, Q96G04 (See
protein sequence)Recommended Name: Protein FAM86A Size: 330 amino acids; 36915 Da
Secondary accessions: D3DUF0 Q96S85Alternative splicing: 2 isoforms: Q96G04-1 Q96G04-2 Explore the universe of human proteins at neXtProt for FAM86A: NX_Q96G04
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96G04
FAM86A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_958802.1 NP_963892.1
ENSEMBL proteins: ENSP00000389710 ENSP00000398502 ENSP00000464781 ENSP00000464773 ENSP00000468599 ENSP00000467790
Human Recombinant Protein Products for FAM86A:
FAM86A Antibody Products:
Assay Products for FAM86A: |
Protein
Domains /
Families
for FAM86A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM86A for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96G04ProtoNet protein and cluster: Q96G04 UniProtKB/Swiss-Prot: FA86A_HUMAN, Q96G04Similarity: Belongs to the FAM86 family |
Function
for FAM86A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86A (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): FAM86A (NM_201400) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM86A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM86A |
|
Pathways & Interactions
for FAM86A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM86A
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for FAM86A (Q96G042, 3 ENSP000003985024) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for FAM86A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM86A
Search CenterWatch for drugs/clinical trials and news about FAM86A / FA86A
|
Transcripts
for FAM86A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM86A gene (2 alternative transcripts): NM_201400.2 NM_201598.2 Unigene Cluster for FAM86A: Family with sequence similarity 86, member A Hs.406461 [show with all ESTs]Unigene Representative Sequence: NM_2014009 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000458008(uc002cyp.2) ENST00000427587(uc002cyo.2) ENST00000585436
ENST00000587161 ENST00000587608 ENST00000587133 ENST00000587200 ENST00000585975
ENST00000586444
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86A (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86A (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): FAM86A (NM_201400) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM86A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM86A |
Additional cDNA sequence: AY037162.1 BC010084.2 12 DOTS entries: DT.101959683 DT.450414 DT.100774611 DT.100649176 DT.91640933 DT.120724745 DT.95277931 DT.120724713 DT.92448405 DT.95277944 DT.100785068 DT.100825780 24/120 AceView cDNA sequences (see all 120): NM_201598 BU631769 BI258244 BX405218 BI770843 AA642247 CB119491 BG683078 NM_201400 AA812261 BV203183 AW246994 BE908025 BM818665 AY037162 BX440187 BV203229 BX366006 BV203230 BC010084 BX378184 BV203193 BG717384 BV203233
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM86A About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 |
|---|
|
| SP1: | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for FAM86A
|
Expression
for FAM86A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM86A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGCAGAAACT
About this image
See FAM86A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM86A
SOURCE GeneReport for Unigene cluster: Hs.406461
SABiosciences Custom PCR Arrays for FAM86A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM86A
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM86A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM86A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM86A |
Orthologs
for FAM86A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for FAM86A gene from 7/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM86A1 |
family with sequence similarity 86, member A |
61.22(n)
58.97(a) |
|
416392 NM_001030627.1 NP_001025798.1 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
55(a) |
1 → many |
GL343402.1(678506-686747) |
zebrafish
(Danio rerio) |
Actinopterygii |
fam86a1 |
family with sequence similarity 86, member A |
56.88(n)
49.49(a) |
|
450038 NM_001006058.1 NP_001006058.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG78891 |
CG7889 |
44.78(n)
33.21(a) |
|
32916 NM_133140.2 NP_573368.2 |
worm
(Caenorhabditis elegans) |
Secernentea |
R08D7.46 |
Uncharacterized protein R08D7.4 |
21(a) |
1 → many |
III(8971815-8973872) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G274006 |
S-adenosyl-L-methionine-dependent methyltransferas... |
21(a) |
1 → many |
5(9676334-9678503) |
rice
(Oryza sativa) |
Liliopsida |
-- |
GA20663-PA, putative, expressed |
23(a) |
1 → many |
5(2494958-2499418) |
ENSEMBL Gene Tree for FAM86A (if available)
TreeFam Gene Tree for FAM86A (if available) |
Paralogs
for FAM86A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM86A gene
- FAM86B12 FAM86C12 FAM86B22
4 SIMAP similar genes for FAM86A using alignment to 6 protein entries: FA86A_HUMAN (see all proteins):FAM86C1 FAM86C2P FAM86B1 FAM86B2
FAM86A for paralogs About GeneDecksing
5/10 Pseudogenes.org Pseudogenes for FAM86A (see all 10)
PGOHUM00000242119 PGOHUM00000257838 PGOHUM00000250408 PGOHUM00000250245 PGOHUM00000250256
|
Genomic Variants
for FAM86A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM86A (5134301 - 5147809 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 9 variations for FAM86A
9 CNVs: 87946 72445 9755 8811 5436 3989 3101 72444 77164 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM86A |
|
Disorders
/ Diseases
for FAM86A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 FAM86A for disorders About MalaCards
FAM86A for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: FAM86A (1 document)
Export disorders for FAM86A gene to outside databases
|
Publications
for FAM86A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM86A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM86A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for FAM86A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM86A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM86A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM86A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM86A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM86A gene:
Search GeneIP for patents involving FAM86A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM86A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM86A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM86A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM86A | | | OriGene Protein Over-expression Lysate for FAM86A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM86A | | OriGene 3'-UTR Clone for FAM86A | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM86A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM86A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM86A | | OriGene Custom Protein Services for FAM86A | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM86A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM86A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM86A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM86A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM86A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM86A |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM86A |
| |  |  |  |  | | | | |
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 | | | FAM86A Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | ThermoFisher Antibodies for FAM86A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM86A |
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