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Aliases for FAM84B Gene

Aliases for FAM84B Gene

  • Family With Sequence Similarity 84, Member B 2 3
  • BCMP101 3 4 6
  • Breast Cancer Membrane-Associated Protein 101 2 3
  • Breast Cancer Membrane Protein 101 3 4
  • Neurological/Sensory 2 2 3
  • NSE2 3 4
  • Protein FAM84B 3
  • Protein NSE2 4

External Ids for FAM84B Gene

Previous GeneCards Identifiers for FAM84B Gene

  • GC08M127634
  • GC08M122881
  • GC08M127564

Summaries for FAM84B Gene

GeneCards Summary for FAM84B Gene

FAM84B (Family With Sequence Similarity 84, Member B) is a Protein Coding gene. Diseases associated with FAM84B include gastroesophageal junction adenocarcinoma and breast cancer. An important paralog of this gene is FAM84A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM84B Gene

Genomics for FAM84B Gene

Regulatory Elements for FAM84B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM84B Gene

126,552,438 bp from pter
126,558,472 bp from pter
6,035 bases
Minus strand

Genomic View for FAM84B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM84B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM84B Gene

Proteins for FAM84B Gene

  • Protein details for FAM84B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM84B
    Protein Accession:
    Secondary Accessions:

    Protein attributes for FAM84B Gene

    310 amino acids
    Molecular mass:
    34474 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM84B Gene

Proteomics data for FAM84B Gene at MOPED

Post-translational modifications for FAM84B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM84B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM84B Gene

Domains for FAM84B Gene

Protein Domains for FAM84B Gene


Suggested Antigen Peptide Sequences for FAM84B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM84 family.
  • Belongs to the FAM84 family.
genes like me logo Genes that share domains with FAM84B: view

No data available for Gene Families for FAM84B Gene

Function for FAM84B Gene

Gene Ontology (GO) - Molecular Function for FAM84B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 12477722
genes like me logo Genes that share ontologies with FAM84B: view

Animal Model Products

CRISPR Products

miRNA for FAM84B Gene

miRTarBase miRNAs that target FAM84B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM84B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM84B Gene

Localization for FAM84B Gene

Subcellular locations from

Jensen Localization Image for FAM84B Gene COMPARTMENTS Subcellular localization image for FAM84B gene
Compartment Confidence
plasma membrane 4
cytosol 2
nucleus 2

Gene Ontology (GO) - Cellular Components for FAM84B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA 12477722
GO:0005886 plasma membrane IDA 12477722
genes like me logo Genes that share ontologies with FAM84B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM84B Gene

Pathways for FAM84B Gene

SuperPathways for FAM84B Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM84B Gene


No data available for Pathways by source for FAM84B Gene

Transcripts for FAM84B Gene

mRNA/cDNA for FAM84B Gene

Unigene Clusters for FAM84B Gene

Family with sequence similarity 84, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM84B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM84B Gene

No ASD Table

Relevant External Links for FAM84B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM84B Gene

mRNA expression in normal human tissues for FAM84B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues for FAM84B Gene

This gene is overexpressed in Salivary gland (27.3), Stomach (9.9), and Breast (8.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM84B Gene

SOURCE GeneReport for Unigene cluster for FAM84B Gene Hs.741352

mRNA Expression by UniProt/SwissProt for FAM84B Gene

Tissue specificity: Expressed in esophageal squamous cell carcinomas.
genes like me logo Genes that share expressions with FAM84B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and Expression partners for FAM84B Gene

Orthologs for FAM84B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM84B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM84B 35
  • 89.74 (n)
  • 93.71 (a)
FAM84B 36
  • 92 (a)
(Canis familiaris)
Mammalia FAM84B 35
  • 93.16 (n)
  • 94.02 (a)
FAM84B 36
  • 94 (a)
(Mus musculus)
Mammalia Fam84b 35
  • 86.88 (n)
  • 92.58 (a)
Fam84b 16
Fam84b 36
  • 93 (a)
(Pan troglodytes)
Mammalia FAM84B 35
  • 100 (n)
  • 100 (a)
FAM84B 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam84b 35
  • 86.13 (n)
  • 92.58 (a)
(Monodelphis domestica)
Mammalia FAM84B 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia FAM84B 36
  • 73 (a)
(Gallus gallus)
Aves FAM84B 35
  • 77.86 (n)
  • 79.34 (a)
FAM84B 36
  • 61 (a)
(Anolis carolinensis)
Reptilia FAM84B 36
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101733578 35
  • 73.02 (n)
  • 68.13 (a)
(Danio rerio)
Actinopterygii fam84b 35
  • 67.18 (n)
  • 67.05 (a)
fam84b 36
  • 65 (a)
FAM84B (2 of 2) 36
  • 61 (a)
Species with no ortholog for FAM84B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM84B Gene

Gene Tree for FAM84B (if available)
Gene Tree for FAM84B (if available)

Paralogs for FAM84B Gene

Paralogs for FAM84B Gene

(1) SIMAP similar genes for FAM84B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM84B: view

Variants for FAM84B Gene

Sequence variations from dbSNP and Humsavar for FAM84B Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs2290840 -- 126,558,266(+) GCGCT(G/T)CCTCC utr-variant-5-prime, nc-transcript-variant, upstream-variant-2KB
rs2305976 -- 126,556,366(+) AGACA(C/G)TGGCA utr-variant-3-prime, nc-transcript-variant
rs6982970 -- 126,555,893(+) GACCT(C/T)GTCAT utr-variant-3-prime, intron-variant
rs9643213 -- 126,555,284(+) TCAGC(C/G)TAAGA utr-variant-3-prime, intron-variant
rs11539702 -- 126,552,939(+) ATGAT(A/G)TCAAG utr-variant-3-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM84B Gene

Variant ID Type Subtype PubMed ID
esv2737545 CNV Deletion 23290073
nsv7419 OTHER Inversion 18451855
nsv499795 OTHER Inversion 21111241

Relevant External Links for FAM84B Gene

HapMap Linkage Disequilibrium report

PCR Panel Products

  • Copy Number PCR Panels: for FAM84B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM84B Gene

Disorders for FAM84B Gene

Relevant External Links for FAM84B

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with FAM84B: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM84B Gene

Publications for FAM84B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Negative implication of C-MYC as an amplification target in esophageal cancer. (PMID: 16490593) Huang X.-P. … Liang Q.-W. (Cancer Genet. Cytogenet. 2006) 3 4
  3. Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer. (PMID: 20158306) White K.L. … Goode E.L. (Twin Res Hum Genet 2010) 3 48
  4. Comprehensive proteomic analysis of breast cancer cell membranes reveals unique proteins with potential roles in clinical cancer. (PMID: 12477722) Adam P.J. … Terrett J.A. (J. Biol. Chem. 2003) 2 3
  5. Evaluation of the 8q24 prostate cancer risk locus and MYC expression. (PMID: 19549893) Pomerantz M.M. … Freedman M.L. (Cancer Res. 2009) 3 48

Products for FAM84B Gene

Sources for FAM84B Gene

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