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Aliases for FAM84A Gene

Aliases for FAM84A Gene

  • Family With Sequence Similarity 84, Member A 2 3
  • Neurologic Sensory Protein 1 3 4
  • Neurological/Sensory 1 2 3
  • NSE1 3 4
  • Protein FAM84A 3
  • PP11517 3

External Ids for FAM84A Gene

Previous GeneCards Identifiers for FAM84A Gene

  • GC02P014724
  • GC02P014773

Summaries for FAM84A Gene

GeneCards Summary for FAM84A Gene

FAM84A (Family With Sequence Similarity 84, Member A) is a Protein Coding gene. An important paralog of this gene is FAM84B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM84A Gene

Genomics for FAM84A Gene

Regulatory Elements for FAM84A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM84A Gene

Start:
14,632,686 bp from pter
End:
14,650,814 bp from pter
Size:
18,129 bases
Orientation:
Plus strand

Genomic View for FAM84A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM84A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM84A Gene

Proteins for FAM84A Gene

  • Protein details for FAM84A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96KN4-FA84A_HUMAN
    Recommended name:
    Protein FAM84A
    Protein Accession:
    Q96KN4
    Secondary Accessions:
    • A6NP76
    • Q86UZ2
    • Q8NAH7
    • Q8TAM5

    Protein attributes for FAM84A Gene

    Size:
    292 amino acids
    Molecular mass:
    32491 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM84A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM84A Gene

Proteomics data for FAM84A Gene at MOPED

Post-translational modifications for FAM84A Gene

Other Protein References for FAM84A Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for FAM84A Gene

Domains for FAM84A Gene

Protein Domains for FAM84A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM84A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96KN4

UniProtKB/Swiss-Prot:

FA84A_HUMAN :
  • Q96KN4
Family:
  • Belongs to the FAM84 family.
genes like me logo Genes that share domains with FAM84A: view

No data available for Gene Families for FAM84A Gene

Function for FAM84A Gene

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM84A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM84A Gene

Localization for FAM84A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM84A Gene COMPARTMENTS Subcellular localization image for FAM84A gene
Compartment Confidence
cytosol 2
nucleus 2
peroxisome 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM84A Gene

Pathways for FAM84A Gene

SuperPathways for FAM84A Gene

No Data Available

Interacting Proteins for FAM84A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000295092%0d%0a9606.ENSP00000358081%0d%0a
Selected Interacting proteins: ENSP00000295092 for FAM84A Gene via STRING

Symbol External ID(s) Details
BAG3

Gene Ontology (GO) - Biological Process for FAM84A Gene

None

No data available for Pathways by source for FAM84A Gene

Transcripts for FAM84A Gene

mRNA/cDNA for FAM84A Gene

Unigene Clusters for FAM84A Gene

Family with sequence similarity 84, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM84A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM84A Gene

No ASD Table

Relevant External Links for FAM84A Gene

GeneLoc Exon Structure for
FAM84A
ECgene alternative splicing isoforms for
FAM84A

Expression for FAM84A Gene

mRNA expression in normal human tissues for FAM84A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM84A Gene

This gene is overexpressed in Esophagus - Mucosa (5.7) and Colon - Transverse (5.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM84A Gene

SOURCE GeneReport for Unigene cluster for FAM84A Gene Hs.260855

genes like me logo Genes that share expressions with FAM84A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM84A Gene

Orthologs for FAM84A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM84A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM84A 35
  • 99.54 (n)
  • 100 (a)
FAM84A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM84A 35
  • 93.61 (n)
  • 97.6 (a)
FAM84A 36
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM84A 35
  • 95.09 (n)
  • 98.29 (a)
FAM84A 36
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam84a 35
  • 91.67 (n)
  • 96.23 (a)
Fam84a 16
Fam84a 36
  • 96 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM84A 36
  • 81 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM84A 36
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam84a 35
  • 90.53 (n)
  • 96.23 (a)
chicken
(Gallus gallus)
Aves FAM84A 35
  • 80.26 (n)
  • 82.27 (a)
FAM84A 36
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM84A 36
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam84a 35
  • 68.38 (n)
  • 70.7 (a)
zebrafish
(Danio rerio)
Actinopterygii fam84a 35
  • 69.1 (n)
  • 64.62 (a)
fam84a 36
  • 63 (a)
OneToOne
zgc63724 35
Species with no ortholog for FAM84A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM84A Gene

ENSEMBL:
Gene Tree for FAM84A (if available)
TreeFam:
Gene Tree for FAM84A (if available)

Paralogs for FAM84A Gene

Paralogs for FAM84A Gene

Selected SIMAP similar genes for FAM84A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM84A: view

Variants for FAM84A Gene

Sequence variations from dbSNP and Humsavar for FAM84A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs2571612 -- 14,631,020(-) TGCTG(A/G)AAAAA upstream-variant-2KB
rs11885903 -- 14,631,681(+) TAGCA(C/T)TGGGG upstream-variant-2KB
rs13021702 -- 14,632,551(+) gcggg(A/G)cggag upstream-variant-2KB
rs13422848 -- 14,631,614(+) AAATT(A/C)CTCAT upstream-variant-2KB
rs36004065 -- 14,631,598(+) TCAAA(G/T)AGGAA upstream-variant-2KB

Relevant External Links for FAM84A Gene

HapMap Linkage Disequilibrium report
FAM84A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM84A Gene

Disorders for FAM84A Gene

Relevant External Links for FAM84A

Genetic Association Database (GAD)
FAM84A
genes like me logo Genes that share disorders with FAM84A: view

No data available for UniProtKB/Swiss-Prot for FAM84A Gene

Publications for FAM84A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4
  4. A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. (PMID: 16820875) Kobayashi T. … Nakamura Y. (Int. J. Oncol. 2006) 3
  5. Nse1 RING-like domain supports functions of the Smc5-Smc6 holocomplex in genome stability. (PMID: 18667531) Pebernard S. … Boddy M.N. (Mol. Biol. Cell 2008) 3

Products for FAM84A Gene

Sources for FAM84A Gene

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