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Aliases for FAM83F Gene

Aliases for FAM83F Gene

  • Family With Sequence Similarity 83, Member F 2 3

External Ids for FAM83F Gene

Previous GeneCards Identifiers for FAM83F Gene

  • GC22P038716
  • GC22P040390
  • GC22P023353

Summaries for FAM83F Gene

GeneCards Summary for FAM83F Gene

FAM83F (Family With Sequence Similarity 83, Member F) is a Protein Coding gene. An important paralog of this gene is FAM83D.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM83F Gene

Genomics for FAM83F Gene

Regulatory Elements for FAM83F Gene

Genomic Location for FAM83F Gene

Start:
39,994,949 bp from pter
End:
40,043,529 bp from pter
Size:
48,581 bases
Orientation:
Plus strand

Genomic View for FAM83F Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM83F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM83F Gene

Proteins for FAM83F Gene

  • Protein details for FAM83F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NEG4-FA83F_HUMAN
    Recommended name:
    Protein FAM83F
    Protein Accession:
    Q8NEG4
    Secondary Accessions:
    • Q96FD6

    Protein attributes for FAM83F Gene

    Size:
    500 amino acids
    Molecular mass:
    55486 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM83F Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM83F Gene

Proteomics data for FAM83F Gene at MOPED

Post-translational modifications for FAM83F Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM83F Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM83F Gene

Domains for FAM83F Gene

Protein Domains for FAM83F Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM83F Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NEG4

UniProtKB/Swiss-Prot:

FA83F_HUMAN :
  • Q8NEG4
Family:
  • Belongs to the FAM83 family.
genes like me logo Genes that share domains with FAM83F: view

No data available for Gene Families for FAM83F Gene

Function for FAM83F Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM83F Gene

Localization for FAM83F Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM83F Gene COMPARTMENTS Subcellular localization image for FAM83F gene
Compartment Confidence
cytosol 2
nucleus 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM83F Gene

Pathways for FAM83F Gene

SuperPathways for FAM83F Gene

No Data Available

Interacting Proteins for FAM83F Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000330432%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000330432 Q8NEG4-FA83F_HUMAN for FAM83F Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM83F Gene

None

No data available for Pathways by source for FAM83F Gene

Transcripts for FAM83F Gene

mRNA/cDNA for FAM83F Gene

Unigene Clusters for FAM83F Gene

Family with sequence similarity 83, member F:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM83F Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b
SP1:
SP2: - - -
SP3:

Relevant External Links for FAM83F Gene

GeneLoc Exon Structure for
FAM83F
ECgene alternative splicing isoforms for
FAM83F

Expression for FAM83F Gene

mRNA expression in normal human tissues for FAM83F Gene

mRNA differential expression in normal tissues according to GTEx for FAM83F Gene

This gene is overexpressed in Testis (12.3), Esophagus - Mucosa (5.6), Skin - Not Sun Exposed (Suprapubic) (4.7), and Pancreas (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM83F Gene

SOURCE GeneReport for Unigene cluster for FAM83F Gene Hs.197680

genes like me logo Genes that share expressions with FAM83F: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM83F Gene

Orthologs for FAM83F Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM83F Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM83F 35
  • 99.4 (n)
  • 99.4 (a)
FAM83F 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM83F 35
  • 86.51 (n)
  • 81.76 (a)
FAM83F 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM83F 35
  • 85.33 (n)
  • 79.6 (a)
FAM83F 36
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam83f 35
  • 83.44 (n)
  • 81.26 (a)
Fam83f 16
Fam83f 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM83F 36
  • 62 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM83F 36
  • 77 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam83f 35
  • 83.27 (n)
  • 80.44 (a)
chicken
(Gallus gallus)
Aves FAM83F 35
  • 64.79 (n)
  • 59.79 (a)
FAM83F 36
  • 60 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM83F 36
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam83f 35
  • 62.05 (n)
  • 56.92 (a)
zebrafish
(Danio rerio)
Actinopterygii FAM83F (2 of 2) 36
  • 32 (a)
OneToMany
fam83fb 36
  • 36 (a)
OneToMany
si:dkey-165i8.3 35
  • 58.5 (n)
  • 48.99 (a)
Species with no ortholog for FAM83F:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM83F Gene

ENSEMBL:
Gene Tree for FAM83F (if available)
TreeFam:
Gene Tree for FAM83F (if available)

Paralogs for FAM83F Gene

Paralogs for FAM83F Gene

Selected SIMAP similar genes for FAM83F Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM83F: view

Variants for FAM83F Gene

Sequence variations from dbSNP and Humsavar for FAM83F Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type MAF
rs714008 -- 40,010,268(+) TCGCT(C/T)GGTGT intron-variant
rs732748 -- 40,027,435(+) GCTCC(A/C/G)CTCCG intron-variant
rs737815 -- 40,023,150(+) TCTCC(C/G)CTTCT intron-variant
rs739145 -- 40,002,841(+) GTGAC(A/G/T)GGATC intron-variant
rs743840 -- 40,023,613(+) TTCTG(C/T)GTGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM83F Gene

Variant ID Type Subtype PubMed ID
nsv834201 CNV Gain 17160897
esv2676686 CNV Deletion 23128226
esv2452848 CNV Insertion 19546169
nsv829229 CNV Loss 20364138

Relevant External Links for FAM83F Gene

HapMap Linkage Disequilibrium report
FAM83F

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM83F Gene

Disorders for FAM83F Gene

Relevant External Links for FAM83F

Genetic Association Database (GAD)
FAM83F
Human Genome Epidemiology (HuGE) Navigator
FAM83F
genes like me logo Genes that share disorders with FAM83F: view

No data available for UniProtKB/Swiss-Prot for FAM83F Gene

Publications for FAM83F Gene

  1. Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging. (PMID: 19834535) Wheeler H.E. … Kim S.K. (PLoS Genet. 2009) 3 48
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. HSP27 and HSP70 interact with CD10 in C4-2 prostate cancer cells. (PMID: 17342744) Dall'Era M.A. … Liu A.Y. (Prostate 2007) 3
  4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PMID: 21906983) Kim W. … Gygi S.P. (Mol. Cell 2011) 3

Products for FAM83F Gene

Sources for FAM83F Gene

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