Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FAM83D Gene

protein-coding GIFtS: 41
GCID: GC20P037554

family with sequence similarity 83, member D

(Previous name: chromosome 20 open reading frame 129 )
(Previous symbol: C20orf129)

Search for FAM83D
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Family With Sequence Similarity 83, Member D¹ ²		Chromosome 20 Open Reading Frame 129¹
C20orf129¹ ² ³		CHICA²
DJ616B8.3¹		Protein FAM83D²
Spindle Protein CHICA² ³

External Ids:	HGNC: 16122¹	Entrez Gene: 81610²	Ensembl: ENSG00000101447⁷	UniProtKB: Q9H4H8³

Export aliases for FAM83D gene to outside databases

Previous GC identifers: GC20P036989 GC20P034292

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: FA83D_HUMAN, Q9H4H8

Function: Required for proper chromosome congression and alignment during mitosis. Required for targeting KIF22/KID to

the spindle microtubules

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011362.10

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FAM83D gene promoter:
p53 Pax-5 POU3F1 E4BP4 E47 AREB6 Max Hand1 Pax-4a c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FAM83D promoter sequence

Search SABiosciences Chromatin IP Primers for FAM83D

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM83D

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.22-q12 Ensembl cytogenetic band: 20q11.23 HGNC chromosome: 20

FAM83D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM83D gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P037554: view genomic region (about GC identifiers)

Start:	37,554,955 bp from pter	End:	37,581,703 bp from pter
Size:	26,749 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FA83D_HUMAN, Q9H4H8 (See protein sequence)

Recommended Name: Protein FAM83D

Size: 585 amino acids; 64424 Da

Subunit: Interacts with KIF22/KID

Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole.

Note=Primarily cytoplasmic during interphase, but beginning in prophase, associates with spindle microtubules, with a

clear concentration toward the spindle poles. It persists on spindle microtubules through metaphase and anaphase

Miscellaneous: Was named CHICA (girl in Spanish) because it interacts with KID

Sequence caution: Sequence=AAH01068.2; Type=Erroneous initiation; Sequence=AAH06553.3; Type=Erroneous initiation;

Sequence=AAH53683.1; Type=Erroneous initiation; Sequence=AAH63661.1; Type=Erroneous initiation; Sequence=AAH80188.1;

Type=Erroneous initiation; Sequence=BAB71016.1; Type=Erroneous termination; Positions=262; Note=Translated as Trp;

Sequence=CAI22033.1; Type=Erroneous initiation;

Secondary accessions: B4E1I7 Q5THR2 Q68EN1 Q6P457 Q7Z6H0 Q96DF5 Q96N89 Q9BVM8

Alternative splicing: 2 isoforms: Q9H4H8-1 Q9H4H8-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM83D: NX_Q9H4H8

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9H4H8

FAM83D Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_112181.2

ENSEMBL proteins:

ENSP00000217429

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: FAM83D OriGene Protein Over-expression Lysate: FAM83D OriGene Custom Protein Services for FAM83D
	GenScript Custom Purified and Recombinant Proteins Services for FAM83D
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FAM83D

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000922	spindle pole	IEA	--
GO:0005737	cytoplasm	IEA	--

FAM83D for ontologies About GeneDecksing

FAM83D Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for FAM83D
	GenScript Custom Superior Antibodies Services for FAM83D
	Search for Antibodies for FAM83D at Abcam
	Uscn Antibodies for FAM83D
	Search ThermoFisher Antibodies for FAM83D

Assay Products for FAM83D:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for FAM83D
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for FAM83D

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FAM83D for domains About GeneDecksing

1 InterPro domain/family:

IPR012461 DUF1669

Graphical View of Domain Structure for InterPro Entry Q9H4H8

ProtoNet protein and cluster: Q9H4H8

1 Blocks protein family: IPB012461 Protein of unknown function DUF1669

UniProtKB/Swiss-Prot: FA83D_HUMAN, Q9H4H8

Similarity: Belongs to the FAM83 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: FA83D_HUMAN, Q9H4H8

Function: Required for proper chromosome congression and alignment during mitosis. Required for targeting KIF22/KID to

the spindle microtubules

miRNA Products:		OriGene 3'-UTR Clone: FAM83D Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM83D
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM83D:
		hsa-miR-19b hsa-miR-4255 hsa-miR-19a hsa-miR-548aa
		SwitchGear 3'UTR luciferase reporter plasmid: FAM83D 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM83D (see all 4) OriGene shRNA RFP: FAM83D OriGene siRNA: FAM83D
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM83D

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FAM83D

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM83D (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM83D (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: FAM83D (NM_030919)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM83D
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM83D

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FAM83D
		Search LifeMap BioReagents cell lines for FAM83D

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM83D

2 GenomeRNAi human phenotypes for FAM83D:

Increased gamma-H2AX phosphory

Increased number of cells in m

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FAM83D

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

5 Interacting proteins for FAM83D (Q9H4H8^{2, 3} ENSP00000217429⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CSNK1E	P49674²^,³	MINT-8252736 I2D: score=2
DYNC1I1	O14576²^,³	MINT-8254866 I2D: score=2
GADD45A	P24522²^,³	MINT-8255794 I2D: score=2
GSK3B	P49841²^,³	MINT-8257196 I2D: score=2
UBC	ENSP00000344818⁴	STRING: ENSP00000344818

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007067	mitosis	IEA	--
GO:0051301	cell division	IEA	--

FAM83D for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM83D
Search CenterWatch for drugs/clinical trials and news about FAM83D / FA83D

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FAM83D gene:

NM_030919.2

Unigene Cluster for FAM83D:

Family with sequence similarity 83, member D

Hs.726442 [show with all ESTs]

Unigene Representative Sequence: AL832274

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000217429(uc002xjf.3 uc002xjg.3)

miRNA Products:		OriGene 3'-UTR Clone: FAM83D Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM83D
		4 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM83D:
		hsa-miR-19b hsa-miR-4255 hsa-miR-19a hsa-miR-548aa
		SwitchGear 3'UTR luciferase reporter plasmid: FAM83D 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM83D (see all 4) OriGene shRNA RFP: FAM83D OriGene siRNA: FAM83D
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM83D

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM83D (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM83D (see all 3) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: FAM83D (NM_030919)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM83D
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM83D

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM83D Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat FAM83D
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM83D
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM83D

Additional cDNA sequence:

AK055793.1 AK095660.1 AK303860.1 AL832274.1 BC001068.2 BC006553.2 BC053683.1 BC063661.1

BC080188.1

6 DOTS entries:

DT.213157 DT.100832065 DT.40219684 DT.100024967 DT.100807246 DT.100660631

24/353 AceView cDNA sequences (see all 353):

BQ063362 AW500225 AA809943 BQ008740 AI057204 Z43700 AA743441 AA488678

AI689511 BG180317 AA639374 CA428446 BU859390 BQ883443 AA279989 BM722056

AW576471 AI796725 CF143914 BQ642453 BM470066 AW000961 BQ058014 AA323743

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAM83D expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTACAGGT

About this image

FAM83D expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 3 LifeMap Cells

Name

Category

PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)

Endothelium

PureStem™ progenitor E44 (Embryonic Progenitor Cell)

PureStem™ progenitor F15 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FAM83D Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM83D

SOURCE GeneReport for Unigene cluster: Hs.726442

SABiosciences Custom PCR Arrays for FAM83D

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM83D Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat FAM83D
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM83D
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM83D

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM83D

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for FAM83D gene from 4/11 species (see all 11) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	FAM83D¹	family with sequence similarity 83, member D	62.11(n) 54.86(a)		425103 XM_422895.3 XP_422895.3
lizard (Anolis carolinensis)	Reptilia	FAM83D⁶	--	47(a)	1 ↔ 1	4(140929360-140953560)
African clawed frog (Xenopus laevis)	Amphibia	Xl.33403²	Xenopus laevis transcribed sequence with weak similarity more	72.45(n)		CA788959.1
zebrafish (Danio rerio)	Actinopterygii	fam83d¹	family with sequence similarity 83, member D	54.2(n) 48.09(a)		492689 NM_001089355.1 NP_001082824.1

ENSEMBL Gene Tree for FAM83D (if available)
TreeFam Gene Tree for FAM83D (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FAM83D gene

FAM83C² FAM83H² FAM83G² FAM83E² FAM83A² FAM83B² FAM83F²

FAM83D for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for FAM83D
PGOHUM00000247655

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs55861510^1,2	C	--	37552957(+)	`ACATGA/GAAGTC`	1	--	us2k¹		0	--	--	--	--
rs59002975^1,2	F,	--	37552961(+)	`GGAAGT/GCCCCA`	1	--	us2k¹		3		WA NA EA	358
rs142730633^1,2		--	37552964(+)	`AGTCCC/GCACAC`	1	--	us2k¹		0	--	--	--	--
rs181652513^1,2		--	37553044(+)	`ACAGCA/GGCAGG`	1	--	us2k¹		0	--	--	--	--
rs140040044^1,2		--	37553234(+)	`CTGATG/TGAAGA`	1	--	us2k¹		0	--	--	--	--
rs117513386^1,2	F,	--	37553345(+)	`TGTCAC/TCCAGG`	1	--	us2k¹		1		NA	120
rs62201394^1,2		--	37553476(+)	`TAGGCG/ACACCA`	1	--	us2k¹		2		NA WA	120
rs144142994^1,2		--	37553501(+)	`CTTTTC/GTATTT`	1	--	us2k¹		0	--	--	--	--
rs186854345^1,2		--	37553513(+)	`TTTGTA/GAAGAC`	1	--	us2k¹		0	--	--	--	--
rs145131008^1,2		--	37553674(+)	`GGGGAA/GCTTTA`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FAM83D (37554955 - 37581703 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM83D: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM83D

DNA2.0 Custom Variant and Variant Library Synthesis for FAM83D

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FAM83D gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with FAM83D)

Utopia: connect your pdf to the dynamic
world of online information

The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle. (PubMed id 18485706)^{1, 2} Santamaria A....Nigg E.A. (2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)¹ Aichem A....Groettrup M. (2012)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)¹ Vinayagam A....Wanker E.E. (2011)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)¹ Lee K.A....Doedens J.R. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 81610	HGNC: 16122	AceView: PPP1R16BandC20orf129	Ensembl:ENSG00000101447	euGenes: HUgn81610
ECgene: FAM83D	H-InvDB: FAM83D

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAM83D	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAM83D gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FAM83D gene:
Search GeneIP for patents involving FAM83D

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for FAM83D
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM83D		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM83D
	OriGene Protein Over-expression Lysate for FAM83D		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for FAM83D		OriGene 3'-UTR Clone for FAM83D
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM83D		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM83D
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for FAM83D		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FAM83D		OriGene Custom Protein Services for FAM83D
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM83D
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM83D
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM83D
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM83D
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM83D
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM83D

	GenScript Custom Purified and Recombinant Proteins Services for FAM83D		GenScript cDNA clones with any tag delivered in your preferred vector for FAM83D
	GenScript Custom Assay Services for FAM83D		GenScript Custom Superior Antibodies Services for FAM83D
	GenScript Custom overexpressing Cell Line Services for FAM83D		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in FAM83D promoter
	Search Chromatin IP Primers for FAM83D
	RT² qPCR Primer Assay in human, mouse / rat FAM83D
	Search GNC Networks for FAM83D
	SABiosciences Custom PCR Arrays for FAM83D

Search Tocris compounds for FAM83D

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Biologicals
	Novus Tissue Slides

	Search for Antibodies for FAM83D at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for FAM83D
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

FAM83D Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for FAM83D

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM83D

	SwitchGear 3'UTR luciferase reporter plasmids for FAM83D
	SwitchGear Promoter luciferase reporter plasmids for FAM83D

Search ThermoFisher Antibodies for FAM83D

Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM83D

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FAM83D gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

FAM83D Gene

family with sequence similarity 83, member D

Aliases
for FAM83D gene

Summaries
for FAM83D gene

Genomic Views
for FAM83D gene

Proteins
for FAM83D gene

Protein Domains /
Families
for FAM83D gene

Function
for FAM83D gene

Pathways & Interactions
for FAM83D gene

Drugs & Compounds
for FAM83D gene

Transcripts
for FAM83D gene

Expression
for FAM83D gene

Orthologs
for FAM83D gene

Paralogs
for FAM83D gene

Genomic Variants
for FAM83D gene

Disorders / Diseases
for FAM83D gene

Publications
for FAM83D gene

External Searches for FAM83D gene

Genome Databases showing FAM83D gene

Other Databases showing FAM83D gene

Specialized Databases showing FAM83D gene

Intellectual Property
for FAM83D gene

Products
for FAM83D gene

View Random Gene

Advanced Search

Export list of displayed genes

FAM83D Gene

family with sequence similarity 83, member D

Aliasesfor FAM83D gene

Summariesfor FAM83D gene

Genomic Viewsfor FAM83D gene

Proteinsfor FAM83D gene

Protein Domains /Familiesfor FAM83D gene

Functionfor FAM83D gene

Pathways & Interactionsfor FAM83D gene

Drugs & Compoundsfor FAM83D gene

Transcriptsfor FAM83D gene

Expression for FAM83D gene

Orthologsfor FAM83D gene

Paralogsfor FAM83D gene

Genomic Variantsfor FAM83D gene

Disorders / Diseasesfor FAM83D gene

Publicationsfor FAM83D gene

External Searches for FAM83D gene

Genome Databases showing FAM83D gene

Other Databases showing FAM83D gene

Specialized Databases showing FAM83D gene

Intellectual Propertyfor FAM83D gene

Productsfor FAM83D gene

View Random Gene

Aliases
for FAM83D gene

Summaries
for FAM83D gene

Genomic Views
for FAM83D gene

Proteins
for FAM83D gene

Protein Domains /
Families
for FAM83D gene

Function
for FAM83D gene

Pathways & Interactions
for FAM83D gene

Drugs & Compounds
for FAM83D gene

Transcripts
for FAM83D gene

Expression
for FAM83D gene

Orthologs
for FAM83D gene

Paralogs
for FAM83D gene

Genomic Variants
for FAM83D gene

Disorders / Diseases
for FAM83D gene

Publications
for FAM83D gene

Intellectual Property
for FAM83D gene

Products
for FAM83D gene