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Aliases for FAM78B Gene

Aliases for FAM78B Gene

  • Family With Sequence Similarity 78, Member B 2 3

External Ids for FAM78B Gene

Previous GeneCards Identifiers for FAM78B Gene

  • GC01M162772
  • GC01M164293
  • GC01M164305
  • GC01M166027
  • GC01M137286

Summaries for FAM78B Gene

GeneCards Summary for FAM78B Gene

FAM78B (Family With Sequence Similarity 78, Member B) is a Protein Coding gene. An important paralog of this gene is FAM78A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM78B Gene

Genomics for FAM78B Gene

Regulatory Elements for FAM78B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM78B Gene

Start:
166,057,426 bp from pter
End:
166,166,969 bp from pter
Size:
109,544 bases
Orientation:
Minus strand

Genomic View for FAM78B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM78B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM78B Gene

Proteins for FAM78B Gene

  • Protein details for FAM78B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VT40-FA78B_HUMAN
    Recommended name:
    Protein FAM78B
    Protein Accession:
    Q5VT40
    Secondary Accessions:
    • B7Z693

    Protein attributes for FAM78B Gene

    Size:
    261 amino acids
    Molecular mass:
    29835 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM78B Gene

Proteomics data for FAM78B Gene at MOPED

Post-translational modifications for FAM78B Gene

No Post-translational modifications

Other Protein References for FAM78B Gene

No data available for DME Specific Peptides for FAM78B Gene

Domains for FAM78B Gene

Protein Domains for FAM78B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM78B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5VT40

UniProtKB/Swiss-Prot:

FA78B_HUMAN :
  • Q5VT40
Family:
  • Belongs to the FAM78 family.
genes like me logo Genes that share domains with FAM78B: view

No data available for Gene Families for FAM78B Gene

Function for FAM78B Gene

Phenotypes for FAM78B Gene

GenomeRNAi human phenotypes for FAM78B:
genes like me logo Genes that share phenotypes with FAM78B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM78B Gene

Localization for FAM78B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM78B Gene COMPARTMENTS Subcellular localization image for FAM78B gene
Compartment Confidence
mitochondrion 2
cytosol 1
endoplasmic reticulum 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM78B Gene

Pathways for FAM78B Gene

SuperPathways for FAM78B Gene

No Data Available

Interacting Proteins for FAM78B Gene

Gene Ontology (GO) - Biological Process for FAM78B Gene

None

No data available for Pathways by source for FAM78B Gene

Transcripts for FAM78B Gene

Unigene Clusters for FAM78B Gene

Family with sequence similarity 78, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM78B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM78B Gene

No ASD Table

Relevant External Links for FAM78B Gene

GeneLoc Exon Structure for
FAM78B
ECgene alternative splicing isoforms for
FAM78B

Expression for FAM78B Gene

mRNA expression in normal human tissues for FAM78B Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

SOURCE GeneReport for Unigene cluster for FAM78B Gene Hs.133029

genes like me logo Genes that share expressions with FAM78B: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for FAM78B Gene

Orthologs for FAM78B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM78B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM78B 35
  • 99.74 (n)
  • 100 (a)
FAM78B 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM78B 35
  • 96.68 (n)
  • 100 (a)
FAM78B 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM78B 35
  • 97.32 (n)
  • 100 (a)
FAM78B 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam78b 35
  • 96.04 (n)
  • 100 (a)
Fam78b 16
Fam78b 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM78B 36
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM78B 36
  • 78 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM78B 35
  • 83.14 (n)
  • 89.66 (a)
FAM78B 36
  • 89 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM78B 36
  • 90 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam78b 35
  • 82.38 (n)
  • 92.72 (a)
zebrafish
(Danio rerio)
Actinopterygii FAM78B (1 of 2) 36
  • 82 (a)
OneToMany
fam78bb 35
  • 75.35 (n)
  • 82.76 (a)
FP102157.1 36
  • 74 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 40 (a)
OneToMany
Species with no ortholog for FAM78B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM78B Gene

ENSEMBL:
Gene Tree for FAM78B (if available)
TreeFam:
Gene Tree for FAM78B (if available)

Paralogs for FAM78B Gene

Paralogs for FAM78B Gene

Selected SIMAP similar genes for FAM78B Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM78B: view

Variants for FAM78B Gene

Sequence variations from dbSNP and Humsavar for FAM78B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs715421 -- 166,152,529(-) AGAGA(A/G)GGAGT intron-variant
rs731264 -- 166,130,684(+) ACTTA(C/G/T)TAATT intron-variant
rs891788 -- 166,122,529(-) GGCCT(A/G)TTAAT intron-variant
rs891789 -- 166,122,312(-) AACCC(C/T)ACTCA intron-variant
rs919674 -- 166,123,802(-) CATGG(C/T)GTGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM78B Gene

Variant ID Type Subtype PubMed ID
esv2719162 CNV Deletion 23290073

Relevant External Links for FAM78B Gene

HapMap Linkage Disequilibrium report
FAM78B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM78B Gene

Disorders for FAM78B Gene

Relevant External Links for FAM78B

Genetic Association Database (GAD)
FAM78B
Human Genome Epidemiology (HuGE) Navigator
FAM78B
genes like me logo Genes that share disorders with FAM78B: view

No data available for UniProtKB/Swiss-Prot for FAM78B Gene

Publications for FAM78B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PMID: 19064610) Cheung C.L. … Kung A.W. (Hum. Mol. Genet. 2009) 3 48
  4. Follow-up of a major linkage peak on chromosome 1 reveals suggestive QTLs associated with essential hypertension: GenNet study. (PMID: 19536175) Ehret G.B. … Chakravarti A. (Eur. J. Hum. Genet. 2009) 3 48
  5. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PMID: 21697133) Oshikawa M. … Kato S. (Invest. Ophthalmol. Vis. Sci. 2011) 3

Products for FAM78B Gene

Sources for FAM78B Gene

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