Aliases for FAM78A Gene
Aliases for FAM78A Gene
External Ids for FAM78A Gene
- HGNC: 25465
- Entrez Gene: 286336
- Ensembl: ENSG00000126882
- UniProtKB: Q5JUQ0
Previous HGNC Symbols for FAM78A Gene
- C9orf59
Previous GeneCards Identifiers for FAM78A Gene
- GC09M131165
- GC09M133123
- GC09M134133
- GC09M103624
Summaries for FAM78A Gene
GeneCards Summary for FAM78A Gene
FAM78A (Family With Sequence Similarity 78 Member A) is a Protein Coding gene. An important paralog of this gene is FAM78B.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM78A Gene
Genomics for FAM78A Gene
Regulatory Elements for FAM78A Gene
Enhancers for FAM78A Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM78A on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for FAM78A Gene
- Chromosome:
- 9
- Start:
- 131,258,076 bp from pter
- End:
- 131,281,920 bp from pter
- Size:
- 23,845 bases
- Orientation:
- Minus strand
Genomic View for FAM78A Gene
Genes around FAM78A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q34.13 by Ensembl
- 9q34.13 by Entrez Gene
- 9q34.13 by HGNC
FAM78A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM78A Gene
Proteins for FAM78A Gene
-
Protein details for FAM78A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5JUQ0-FA78A_HUMAN
- Recommended name:
- Protein FAM78A
- Protein Accession:
- Q5JUQ0
- Q86VQ9
- Q9H7P4
Protein attributes for FAM78A Gene
- Size:
- 283 amino acids
- Molecular mass:
- 31968 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH49388.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for FAM78A Gene
Post-translational modifications for FAM78A Gene
Other Protein References for FAM78A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for FAM78A
- Invitrogen Antibodies for FAM78A
- GeneTex FAM78A antibody for FAM78A
Protein Products
-
OriGene Purified Proteins for FAM78A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM78A
- Origene Custom Protein Services for FAM78A
- Search GeneTex for Proteins for FAM78A
Assay Products
No data available for DME Specific Peptides for FAM78A Gene
Domains & Families for FAM78A Gene
Suggested Antigen Peptide Sequences for FAM78A Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5JUQ0- Family:
-
- Belongs to the FAM78 family.
No data available for Gene Families for FAM78A Gene
Function for FAM78A Gene
Phenotypes for FAM78A Gene
- GenomeRNAi human phenotypes for FAM78A:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM78A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM78A gene
- Search ViGene Biosciences for FAM78A
CRISPR Products
-
OriGene CRISPR knockouts for FAM78A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM78A
- GenScript: Design CRISPR guide RNA sequences for FAM78A
miRNA Products
- Search ViGene Biosciences for FAM78A
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for FAM78A
- Browse OriGene Inhibitory RNA Products For FAM78A
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM78A gene
Clone Products
-
OriGene ORF clones in human for FAM78A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM78A
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM78A gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM78A gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM78A gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM78A Gene
Localization for FAM78A Gene
| Compartment | Confidence |
|---|---|
| cytoskeleton | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM78A Gene
Transcripts for FAM78A Gene
mRNA/cDNA for FAM78A Gene
- (3) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (88) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM78A Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM78A
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM78A
- GenScript: Design CRISPR guide RNA sequences for FAM78A
miRNA Products
- Search ViGene Biosciences for FAM78A
Inhibitory RNA Products
- Origene shRNA, RNAi, and siRNA products in human, mouse, rat for FAM78A
- Browse OriGene Inhibitory RNA Products For FAM78A
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM78A gene
Clone Products
-
OriGene ORF clones in human for FAM78A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM78A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Bone (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for FAM78A Gene
This gene is overexpressed in Whole Blood (x7.0), Heart - Atrial Appendage (x5.7), Heart - Left Ventricle (x4.6), and Spleen (x4.5).
This gene is overexpressed in Peripheral blood mononuclear cells (53.4) and CD8 Tcells (12.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM78A Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM78A Gene:
FAM78ASOURCE GeneReport for Unigene cluster for FAM78A Gene:
Hs.143878Primer Products
-
OriGene qPCR primer pairs for FAM78A
No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM78A Gene
Orthologs for FAM78A Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM78A 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM78A 34 |
|
||
| C9ORF59 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | FAM78A 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam78a 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam78a 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FAM78A 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM78A 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FAM78A 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | FAM78A 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fam78a 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | fam78ab 34 35 |
|
||
| fam78aa 35 |
|
OneToMany | |||
| Dr.16888 34 |
|
||||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
OneToMany |
- Species where no ortholog for FAM78A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM78A Gene
(8) SIMAP similar genes for FAM78A Gene using alignment to 4 proteins:
Variants for FAM78A Gene
| SNP ID | Clin | Chr 09 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000071474 | -- | 131,275,577(+) | ATGTC(C/T)CTCTG | intron-variant | |
| rs1000088752 | -- | 131,270,828(+) | CTTCA(C/G)GTCTT | intron-variant, upstream-variant-2KB | |
| rs1000117219 | -- | 131,269,863(+) | TATGC(A/G)GGCCC | intron-variant | |
| rs1000217994 | -- | 131,264,300(+) | CCCTG(G/T)CTCAG | intron-variant | |
| rs1000301991 | -- | 131,266,643(+) | ACGCC(A/G)CTGGA | intron-variant |
Residual Variation Intolerance Score:
31% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.83;
17.46% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM78A Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM78A
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM78A Gene
Disorders for FAM78A Gene
Relevant External Links for FAM78A
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM78A
No disorders were found for FAM78A Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM78A Gene
Publications for FAM78A Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Characterization of long cDNA clones from human adult spleen. (PMID: 11214971) Hattori A. … Ohara O. (DNA Res. 2000) 2 3 64
- The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
Products for FAM78A Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FAM78A
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM78A
- Origene Custom Protein Services for FAM78A
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM78A
- Browse OriGene Inhibitory RNA Products For FAM78A
- OriGene qPCR primer pairs for FAM78A
- OriGene CRISPR knockouts for FAM78A
- OriGene ORF clones in human for FAM78A
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FAM78A
- GenScript: Next-day shipping cDNA ORF clone for FAM78A in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM78A
- GenScript Custom Assay Services for FAM78A
- GenScript Custom overexpressing Cell Line Services for FAM78A
- GenScript: Design CRISPR guide RNA sequences for FAM78A
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM78A
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for FAM78A
- Novus Biologicals proteins and lysates for FAM78A
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ViGene Biosciences adenoviral particle packaged cDNA for FAM78A gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM78A gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM78A gene
- Search ViGene Biosciences for FAM78A
- Horizon Cell Lines for FAM78A
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM78A
- VectorBuilder custom plasmid, inducible vectors for FAM78A
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM78A
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM78A Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer