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Aliases for FAM76A Gene

Aliases for FAM76A Gene

  • Family With Sequence Similarity 76 Member A 2 3 5
  • Family With Sequence Similarity 76, Member A 2

External Ids for FAM76A Gene

Previous GeneCards Identifiers for FAM76A Gene

  • GC01P027925
  • GC01P028052
  • GC01P026308

Summaries for FAM76A Gene

GeneCards Summary for FAM76A Gene

FAM76A (Family With Sequence Similarity 76 Member A) is a Protein Coding gene. An important paralog of this gene is FAM76B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM76A Gene

Genomics for FAM76A Gene

Regulatory Elements for FAM76A Gene

Enhancers for FAM76A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM76A on UCSC Golden Path with GeneCards custom track

Promoters for FAM76A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM76A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM76A Gene

27,725,979 bp from pter
27,763,122 bp from pter
37,144 bases
Plus strand

Genomic View for FAM76A Gene

Genes around FAM76A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM76A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM76A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM76A Gene

Proteins for FAM76A Gene

  • Protein details for FAM76A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM76A
    Protein Accession:
    Secondary Accessions:
    • B4DWT3
    • O95565
    • O95566
    • Q8N7J5

    Protein attributes for FAM76A Gene

    307 amino acids
    Molecular mass:
    35049 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM76A Gene


neXtProt entry for FAM76A Gene

Proteomics data for FAM76A Gene at MOPED

Post-translational modifications for FAM76A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM76A Gene

Domains & Families for FAM76A Gene

Protein Domains for FAM76A Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM76 family.
  • Belongs to the FAM76 family.
genes like me logo Genes that share domains with FAM76A: view

No data available for Gene Families for FAM76A Gene

Function for FAM76A Gene

Gene Ontology (GO) - Molecular Function for FAM76A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016929 SUMO-specific protease activity IBA --
genes like me logo Genes that share ontologies with FAM76A: view

Phenotypes for FAM76A Gene

genes like me logo Genes that share phenotypes with FAM76A: view

Animal Model Products

CRISPR Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM76A Gene

Localization for FAM76A Gene

Subcellular locations from

Jensen Localization Image for FAM76A Gene COMPARTMENTS Subcellular localization image for FAM76A gene
Compartment Confidence
nucleus 4
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM76A Gene

Pathways & Interactions for FAM76A Gene

SuperPathways for FAM76A Gene

No Data Available

Interacting Proteins for FAM76A Gene

Gene Ontology (GO) - Biological Process for FAM76A Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM76A Gene

Drugs & Compounds for FAM76A Gene

No Compound Related Data Available

Transcripts for FAM76A Gene

Unigene Clusters for FAM76A Gene

Family with sequence similarity 76, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM76A Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9
SP2: -

Relevant External Links for FAM76A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM76A Gene

mRNA expression in normal human tissues for FAM76A Gene

Protein differential expression in normal tissues from HIPED for FAM76A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (37.1), Adipocyte (11.7), and NK cells (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM76A Gene

SOURCE GeneReport for Unigene cluster for FAM76A Gene Hs.469359

genes like me logo Genes that share expression patterns with FAM76A: view

Protein tissue co-expression partners for FAM76A Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM76A Gene

Orthologs for FAM76A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM76A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM76A 35
  • 94.57 (n)
  • 98.7 (a)
FAM76A 36
  • 99 (a)
(Canis familiaris)
Mammalia FAM76A 35
  • 94.88 (n)
  • 99.02 (a)
FAM76A 36
  • 98 (a)
(Mus musculus)
Mammalia Fam76a 35
  • 91.53 (n)
  • 98.05 (a)
Fam76a 16
Fam76a 36
  • 98 (a)
(Pan troglodytes)
Mammalia FAM76A 35
  • 99.8 (n)
  • 100 (a)
FAM76A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam76a 35
  • 90.34 (n)
  • 97.07 (a)
(Monodelphis domestica)
Mammalia FAM76A 36
  • 87 (a)
(Ornithorhynchus anatinus)
Mammalia FAM76A 36
  • 88 (a)
(Gallus gallus)
Aves FAM76A 35
  • 82.63 (n)
  • 93.81 (a)
FAM76A 36
  • 93 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP005928 35
  • 52.89 (n)
  • 49.12 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4452 35
  • 52.45 (n)
  • 44.41 (a)
CG4452 36
  • 32 (a)
(Caenorhabditis elegans)
Secernentea K04F10.7 35
  • 48.65 (n)
  • 34.04 (a)
K04F10.7 36
  • 27 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 28 (a)
Species with no ortholog for FAM76A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for FAM76A Gene

Gene Tree for FAM76A (if available)
Gene Tree for FAM76A (if available)

Paralogs for FAM76A Gene

Paralogs for FAM76A Gene

(1) SIMAP similar genes for FAM76A Gene using alignment to 3 proteins: Pseudogenes for FAM76A Gene

genes like me logo Genes that share paralogs with FAM76A: view

Variants for FAM76A Gene

Sequence variations from dbSNP and Humsavar for FAM76A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1474573 -- 27,752,254(+) ATTAG(C/T)CTTCT intron-variant
rs1474574 -- 27,752,343(+) TACAA(A/C)ATCCA intron-variant
rs1569432 -- 27,745,325(+) TTTCT(C/T)ATCTG intron-variant
rs1933885 -- 27,730,135(+) AAATT(A/G)ATTCA intron-variant
rs1933886 -- 27,730,255(+) GATCT(C/T)GGCTC intron-variant, reference, missense

Variation tolerance for FAM76A Gene

Residual Variation Intolerance Score: 56.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.64; 13.72% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for FAM76A Gene

Disorders for FAM76A Gene

Relevant External Links for FAM76A

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM76A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM76A Gene

Publications for FAM76A Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 67
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for FAM76A Gene

Sources for FAM76A Gene