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FAM74A4 Gene(RNA Gene)

Family With Sequence Similarity 74 Member A4

GCID:
GC09P061205
GIFtS:
25
Genes Participants
UDN Logo

Aliases for FAM74A4 Gene

Subcategory (RNA class) for FAM74A4 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for FAM74A4 Gene

  • Family With Sequence Similarity 74 Member A4 2 3 5
  • Family With Sequence Similarity 74, Member A2 2 3
  • Family With Sequence Similarity 74, Member A4 2
  • Family With Sequence Similarity 74 Member A2 2
  • FAM74A4 FAM74A6 4
  • FAM74A2 3

External Ids for FAM74A4 Gene

Previous HGNC Symbols for FAM74A4 Gene

  • FAM74A2

Previous GeneCards Identifiers for FAM74A4 Gene

  • GC09M065227
  • GC09M065487

Summaries for FAM74A4 Gene

GeneCards Summary for FAM74A4 Gene

FAM74A4 (Family With Sequence Similarity 74 Member A4) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM74A4 Gene

Genomics for FAM74A4 Gene

Products:

  1. Regulatory Element

Regulatory Elements for FAM74A4 Gene


Transcription factor binding sites by QIAGEN in the FAM74A4 gene promoter:

Genomic Location for FAM74A4 Gene

Chromosome:
9
Start:
61,205,258 bp from pter
End:
61,212,373 bp from pter
Size:
7,116 bases
Orientation:
Plus strand

Genomic View for FAM74A4 Gene

Genes around FAM74A4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM74A4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM74A4 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for FAM74A4 Gene

Proteins for FAM74A4 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for FAM74A4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5TZK3-FAM74_HUMAN
    Recommended name:
    Protein FAM74A4/A6
    Protein Accession:
    Q5TZK3
    Secondary Accessions:
    • A6NH89
    • Q6ZSU6

    Protein attributes for FAM74A4 Gene

    Size:
    123 amino acids
    Molecular mass:
    14773 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM74A4 Gene

Post-translational modifications for FAM74A4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM74A4 Gene

Domains & Families for FAM74A4 Gene

Protein Domains for FAM74A4 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM74A4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5TZK3

UniProtKB/Swiss-Prot:

FAM74_HUMAN :
  • Belongs to the FAM74 family.
Family:
  • Belongs to the FAM74 family.
genes like me logo Genes that share domains with FAM74A4: view

No data available for Gene Families for FAM74A4 Gene

Function for FAM74A4 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Gene Ontology (GO) - Molecular Function for FAM74A4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM74A4: view

Phenotypes for FAM74A4 Gene

GenomeRNAi human phenotypes for FAM74A4:
genes like me logo Genes that share phenotypes with FAM74A4: view

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM74A4 Gene

Localization for FAM74A4 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM74A4 gene
Compartment Confidence
nucleus 2
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
cytosol 1
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM74A4 Gene

Pathways & Interactions for FAM74A4 Gene

No data available for Pathways by source and SIGNOR curated interactions for FAM74A4 Gene

Drugs & Compounds for FAM74A4 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for FAM74A4 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for FAM74A4 Gene

(1) REFSEQ mRNAs :
(4) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM74A4 Gene

No ASD Table

Relevant External Links for FAM74A4 Gene

GeneLoc Exon Structure for
FAM74A4
ECgene alternative splicing isoforms for
FAM74A4

Expression for FAM74A4 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM74A4 Gene

mRNA expression in normal human tissues for FAM74A4 Gene
mRNA expression by GTEx for FAM74A4 Gene

mRNA differential expression in normal tissues according to GTEx for FAM74A4 Gene

This gene is overexpressed in Fallopian Tube (x11.7), Brain - Hippocampus (x9.5), Whole Blood (x7.4), Brain - Hypothalamus (x5.4), and Brain - Nucleus accumbens (basal ganglia) (x5.2).

NURSA nuclear receptor signaling pathways regulating expression of FAM74A4 Gene:

FAM74A4

SOURCE GeneReport for Unigene cluster for FAM74A4 Gene:

Hs.741141
genes like me logo Genes that share expression patterns with FAM74A4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM74A4 Gene

Orthologs for FAM74A4 Gene

Evolution for FAM74A4 Gene

ENSEMBL:
Gene Tree for FAM74A4 (if available)
TreeFam:
Gene Tree for FAM74A4 (if available)

No data available for Orthologs for FAM74A4 Gene

Paralogs for FAM74A4 Gene

(4) SIMAP similar genes for FAM74A4 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM74A4: view

No data available for Paralogs for FAM74A4 Gene

Variants for FAM74A4 Gene

Sequence variations from dbSNP and Humsavar for FAM74A4 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1001707024 -- 61,211,729(-) TATTT(A/G)GAATC nc-transcript-variant
rs1007983616 -- 61,211,440(-) CCTTG(A/G)CCTTC nc-transcript-variant
rs1018528560 -- 61,211,424(-) TGCTG(A/G)GATTA nc-transcript-variant
rs1025513410 -- 61,211,511(-) TAGTA(A/G)AGACA nc-transcript-variant
rs1025544697 -- 61,212,507(-) CGCCA(A/C)TGCAC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for FAM74A4 Gene

Variant ID Type Subtype PubMed ID
esv2837124 CNV deletion 24192839
esv3620475 CNV loss 21293372
esv3620476 CNV gain 21293372
esv3891672 CNV gain+loss 25118596
nsv1075628 CNV deletion 25765185
nsv1126889 CNV deletion 24896259
nsv972712 CNV duplication 23825009

Relevant External Links for FAM74A4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM74A4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM74A4 Gene

Disorders for FAM74A4 Gene

Relevant External Links for FAM74A4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM74A4

No disorders were found for FAM74A4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM74A4 Gene

Publications for FAM74A4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for FAM74A4 Gene

Sources for FAM74A4 Gene

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