Free for academic non-profit institutions. Other users need a Commercial license

FAM74A3 Gene(RNA Gene)

Family With Sequence Similarity 74 Member A3

GCID:
GC09M066970
GIFtS:
25
Genes Participants
UDN Logo

Aliases for FAM74A3 Gene

Subcategory (RNA class) for FAM74A3 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for FAM74A3 Gene

  • Family With Sequence Similarity 74 Member A3 2 3 5
  • Family With Sequence Similarity 74, Member A3 2

External Ids for FAM74A3 Gene

Previous GeneCards Identifiers for FAM74A3 Gene

  • GC09U900754
  • GC09P040706

Summaries for FAM74A3 Gene

GeneCards Summary for FAM74A3 Gene

FAM74A3 (Family With Sequence Similarity 74 Member A3) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM74A3 Gene

Genomics for FAM74A3 Gene

Products:

  1. Regulatory Element

Regulatory Elements for FAM74A3 Gene


Transcription factor binding sites by QIAGEN in the FAM74A3 gene promoter:

Genomic Location for FAM74A3 Gene

Chromosome:
9
Start:
66,970,162 bp from pter
End:
66,977,317 bp from pter
Size:
7,156 bases
Orientation:
Minus strand

Genomic View for FAM74A3 Gene

Genes around FAM74A3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM74A3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM74A3 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for FAM74A3 Gene

Proteins for FAM74A3 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for FAM74A3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4VXF1-F74A3_HUMAN
    Recommended name:
    Putative protein FAM74A3
    Protein Accession:
    Q4VXF1

    Protein attributes for FAM74A3 Gene

    Size:
    159 amino acids
    Molecular mass:
    18188 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM74A3 Gene

Post-translational modifications for FAM74A3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM74A3 Gene

Domains & Families for FAM74A3 Gene

Protein Domains for FAM74A3 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM74A3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4VXF1

UniProtKB/Swiss-Prot:

F74A3_HUMAN :
  • Belongs to the FAM74 family.
Family:
  • Belongs to the FAM74 family.
genes like me logo Genes that share domains with FAM74A3: view

No data available for Gene Families for FAM74A3 Gene

Function for FAM74A3 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Phenotypes for FAM74A3 Gene

GenomeRNAi human phenotypes for FAM74A3:
genes like me logo Genes that share phenotypes with FAM74A3: view

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM74A3 Gene

Localization for FAM74A3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM74A3 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM74A3 gene
Compartment Confidence
nucleus 3
plasma membrane 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
cytosol 1

Gene Ontology (GO) - Cellular Components for FAM74A3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM74A3: view

Pathways & Interactions for FAM74A3 Gene

SuperPathways for FAM74A3 Gene

PathCards logo More details on SuperPathways for FAM74A3
No Data Available

Interacting Proteins for FAM74A3 Gene

Gene Ontology (GO) - Biological Process for FAM74A3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM74A3 Gene

Drugs & Compounds for FAM74A3 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for FAM74A3 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for FAM74A3 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM74A3 Gene

Family with sequence similarity 74, member A3:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM74A3 Gene

No ASD Table

Relevant External Links for FAM74A3 Gene

GeneLoc Exon Structure for
FAM74A3
ECgene alternative splicing isoforms for
FAM74A3

Expression for FAM74A3 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM74A3 Gene

mRNA expression in normal human tissues for FAM74A3 Gene
mRNA expression by GTEx for FAM74A3 Gene

mRNA differential expression in normal tissues according to GTEx for FAM74A3 Gene

This gene is overexpressed in Brain - Hypothalamus (x11.6), Testis (x6.8), Brain - Hippocampus (x6.8), Brain - Caudate (basal ganglia) (x5.9), and Brain - Nucleus accumbens (basal ganglia) (x5.6).

NURSA nuclear receptor signaling pathways regulating expression of FAM74A3 Gene:

FAM74A3

SOURCE GeneReport for Unigene cluster for FAM74A3 Gene:

Hs.723007
genes like me logo Genes that share expression patterns with FAM74A3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM74A3 Gene

Orthologs for FAM74A3 Gene

Evolution for FAM74A3 Gene

ENSEMBL:
Gene Tree for FAM74A3 (if available)
TreeFam:
Gene Tree for FAM74A3 (if available)

No data available for Orthologs for FAM74A3 Gene

Paralogs for FAM74A3 Gene

(5) SIMAP similar genes for FAM74A3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM74A3: view

No data available for Paralogs for FAM74A3 Gene

Variants for FAM74A3 Gene

Sequence variations from dbSNP and Humsavar for FAM74A3 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000150145 -- 66,976,278(-) TCTGG(A/G)CCCAA intron-variant
rs1000317800 -- 66,969,839(-) GCCTG(C/G)CTCAG downstream-variant-500B
rs1000750851 -- 66,978,310(-) GGCCA(A/C)GGTGG upstream-variant-2KB
rs1000936543 -- 66,977,996(-) GTACT(C/T)ATTTA upstream-variant-2KB
rs1001920302 -- 66,978,839(-) TTCTC(C/T)TCTAT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM74A3 Gene

Variant ID Type Subtype PubMed ID
nsv1075621 CNV deletion 25765185
nsv469605 CNV gain 16826518
nsv614322 CNV loss 21841781
nsv831560 CNV gain 17160897
nsv831561 CNV loss 17160897
nsv8456 CNV gain+loss 18304495
nsv972329 CNV duplication 23825009

Relevant External Links for FAM74A3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM74A3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM74A3 Gene

Disorders for FAM74A3 Gene

Relevant External Links for FAM74A3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM74A3

No disorders were found for FAM74A3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM74A3 Gene

Publications for FAM74A3 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 4 64

Products for FAM74A3 Gene

Sources for FAM74A3 Gene

Content
Loading form....