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Aliases for FAM74A1 Gene

Subcategory (RNA class) for FAM74A1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for FAM74A1 Gene

  • Family With Sequence Similarity 74, Member A1 2 3
  • Family With Sequence Similarity 74, Member A5 2 3
  • FAM74A1 FAM74A2 4
  • FAM74A5 3

External Ids for FAM74A1 Gene

Previous HGNC Symbols for FAM74A1 Gene

  • FAM74A5

Previous GeneCards Identifiers for FAM74A1 Gene

  • GC09P039890

Summaries for FAM74A1 Gene

GeneCards Summary for FAM74A1 Gene

FAM74A1 (Family With Sequence Similarity 74, Member A1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM74A1 Gene

Genomics for FAM74A1 Gene

Regulatory Elements for FAM74A1 Gene

Genomic Location for FAM74A1 Gene

Chromosome:
9
Start:
39,371,065 bp from pter
End:
39,376,916 bp from pter
Size:
5,852 bases
Orientation:
Plus strand

Genomic View for FAM74A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM74A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM74A1 Gene

Proteins for FAM74A1 Gene

  • Protein details for FAM74A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5RGS3-F74A1_HUMAN
    Recommended name:
    Protein FAM74A1/A2
    Protein Accession:
    Q5RGS3
    Secondary Accessions:
    • A6NK17

    Protein attributes for FAM74A1 Gene

    Size:
    127 amino acids
    Molecular mass:
    14779 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM74A1 Gene

Proteomics data for FAM74A1 Gene at MOPED

Post-translational modifications for FAM74A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM74A1 Gene

Domains & Families for FAM74A1 Gene

Protein Domains for FAM74A1 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q5RGS3

UniProtKB/Swiss-Prot:

F74A1_HUMAN :
  • Belongs to the FAM74 family.
Family:
  • Belongs to the FAM74 family.
genes like me logo Genes that share domains with FAM74A1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM74A1 Gene

Function for FAM74A1 Gene

Gene Ontology (GO) - Molecular Function for FAM74A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM74A1: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM74A1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM74A1 Gene

Localization for FAM74A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM74A1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for FAM74A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM74A1: view

No data available for Subcellular locations from COMPARTMENTS for FAM74A1 Gene

Pathways & Interactions for FAM74A1 Gene

SuperPathways for FAM74A1 Gene

No Data Available

Interacting Proteins for FAM74A1 Gene

Selected Interacting proteins: Q5RGS3-F74A1_HUMAN for FAM74A1 Gene via UniProtKB

Gene Ontology (GO) - Biological Process for FAM74A1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM74A1 Gene

Drugs & Compounds for FAM74A1 Gene

No Compound Related Data Available

Transcripts for FAM74A1 Gene

mRNA/cDNA for FAM74A1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM74A1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM74A1 Gene

No ASD Table

Relevant External Links for FAM74A1 Gene

GeneLoc Exon Structure for
FAM74A1
ECgene alternative splicing isoforms for
FAM74A1

Expression for FAM74A1 Gene

mRNA expression in normal human tissues for FAM74A1 Gene

mRNA differential expression in normal tissues according to GTEx for FAM74A1 Gene

This gene is overexpressed in Testis (x29.6), Brain - Spinal cord (cervical c-1) (x6.0), Brain - Hippocampus (x4.9), Brain - Caudate (basal ganglia) (x4.3), Brain - Hypothalamus (x4.2), and Brain - Nucleus accumbens (basal ganglia) (x4.0).

SOURCE GeneReport for Unigene cluster for FAM74A1 Gene Hs.553802

genes like me logo Genes that share expression patterns with FAM74A1: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM74A1 Gene

Orthologs for FAM74A1 Gene

Evolution for FAM74A1 Gene

ENSEMBL:
Gene Tree for FAM74A1 (if available)
TreeFam:
Gene Tree for FAM74A1 (if available)

No data available for Orthologs for FAM74A1 Gene

Paralogs for FAM74A1 Gene

(4) SIMAP similar genes for FAM74A1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM74A1: view

No data available for Paralogs for FAM74A1 Gene

Variants for FAM74A1 Gene

Sequence variations from dbSNP and Humsavar for FAM74A1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs62550842 -- 39,370,032(+) AGGCA(C/T)CTGTG upstream-variant-2KB
rs62550843 -- 39,370,497(+) AGTGA(C/G)TGGGA upstream-variant-2KB
rs62550845 -- 39,372,028(+) CAGCT(A/G)ACAGG intron-variant
rs62550846 -- 39,374,592(+) CAAAG(A/C)TTCAA intron-variant
rs62550847 -- 39,374,663(+) ATGTT(G/T)TTATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM74A1 Gene

Variant ID Type Subtype PubMed ID
nsv893089 CNV Loss 21882294
nsv8452 CNV Gain+Loss 18304495
dgv8176n71 CNV Loss 21882294
nsv469605 CNV Complex 16826518
dgv8177n71 CNV Loss 21882294
dgv8178n71 CNV Gain+Loss 21882294

Relevant External Links for FAM74A1 Gene

HapMap Linkage Disequilibrium report
FAM74A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM74A1 Gene

Disorders for FAM74A1 Gene

Relevant External Links for FAM74A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM74A1
genes like me logo Genes that share disorders with FAM74A1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM74A1 Gene

Publications for FAM74A1 Gene

  1. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 67
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for FAM74A1 Gene

Sources for FAM74A1 Gene

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