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Aliases for FAM74A1 Gene

Subcategory (RNA class) for FAM74A1 Gene

lncRNA

Quality Score for this RNA gene is

3

Aliases for FAM74A1 Gene

  • Family With Sequence Similarity 74, Member A1 2 3
  • Family With Sequence Similarity 74, Member A5 2 3
  • FAM74A1 FAM74A2 4
  • FAM74A5 3

External Ids for FAM74A1 Gene

ORGUL Members for FAM74A1 Gene

Previous Symbols for FAM74A1 Gene

  • FAM74A5

Summaries for FAM74A1 Gene

GeneCards Summary for FAM74A1 Gene

FAM74A1 (Family With Sequence Similarity 74, Member A1) is a RNA Gene, and belongs to lncRNA RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM74A1 Gene

Genomics for FAM74A1 Gene

Genomic Location for FAM74A1 Gene

Start:
39,370,919 bp from pter
End:
39,377,942 bp from pter
Size:
7,024 bases
Orientation:
Plus strand

Genomic View for FAM74A1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM74A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM74A1 Gene

Regulatory Elements for FAM74A1 Gene

Proteins for FAM74A1 Gene

  • Protein details for FAM74A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5RGS3-F74A1_HUMAN
    Recommended name:
    Protein FAM74A1/A2
    Protein Accession:
    Q5RGS3
    Secondary Accessions:
    • A6NK17

    Protein attributes for FAM74A1 Gene

    Size:
    127 amino acids
    Molecular mass:
    14779 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM74A1 Gene

Proteomics data for FAM74A1 Gene at MOPED

Post-translational modifications for FAM74A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM74A1 Gene

Domains for FAM74A1 Gene

Gene Families for FAM74A1 Gene

HGNC:
  • LNCRNA :Long non-coding RNAs

Protein Domains for FAM74A1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F74A1_HUMAN
Family:
  • Belongs to the FAM74 family.:
    • Q5RGS3
genes like me logo Genes that share domains with FAM74A1: view

Function for FAM74A1 Gene

Gene Ontology (GO) - Molecular Function for FAM74A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM74A1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM74A1 Gene

Localization for FAM74A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM74A1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM74A1 Gene COMPARTMENTS Subcellular localization image for FAM74A1 gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FAM74A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM74A1: view

Pathways for FAM74A1 Gene

SuperPathways for FAM74A1 Gene

No Data Available

Interacting Proteins for FAM74A1 Gene

Selected Interacting proteins: Q5RGS3-F74A1_HUMAN for FAM74A1 Gene via UniProtKB

Gene Ontology (GO) - Biological Process for FAM74A1 Gene

None

No data available for Pathways by source for FAM74A1 Gene

Transcripts for FAM74A1 Gene

mRNA/cDNA for FAM74A1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for FAM74A1 Gene

No ASD Table

Relevant External Links for FAM74A1 Gene

GeneLoc Exon Structure for
FAM74A1
ECgene alternative splicing isoforms for
FAM74A1

Expression for FAM74A1 Gene

mRNA expression in normal human tissues for FAM74A1 Gene

mRNA differential expression in normal tissues according to GTEx for FAM74A1 Gene

This gene is overexpressed in Testis (29.6), Brain - Spinal cord (cervical c-1) (6.0), Brain - Hippocampus (4.9), Brain - Caudate (basal ganglia) (4.3), Brain - Hypothalamus (4.2), and Brain - Nucleus accumbens (basal ganglia) (4.0).

SOURCE GeneReport for Unigene cluster for FAM74A1 Gene Hs.553802

genes like me logo Genes that share expressions with FAM74A1: view

Orthologs for FAM74A1 Gene

Evolution for FAM74A1 Gene

ENSEMBL:
Gene Tree for FAM74A1 (if available)
TreeFam:
Gene Tree for FAM74A1 (if available)

No data available for Orthologs for FAM74A1 Gene

Paralogs for FAM74A1 Gene

Selected SIMAP similar genes for FAM74A1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM74A1: view

No data available for Paralogs for FAM74A1 Gene

Variants for FAM74A1 Gene

Sequence variations from dbSNP and Humsavar for FAM74A1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs2721729 -- 39,371,915(+) TCACC(A/G)TCCCC intron-variant
rs2721730 -- 39,372,009(+) GGAGA(C/T)GCAGC intron-variant
rs9407252 -- 39,376,690(+) tgaag(C/T)taata intron-variant
rs9408536 -- 39,371,472(+) TCAGA(C/G)GCTGT nc-transcript-variant
rs9408537 -- 39,371,489(+) GAAGA(C/T)GTGGA nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM74A1 Gene

Variant ID Type Subtype PubMed ID
nsv893089 CNV Loss 21882294
nsv8452 CNV Gain+Loss 18304495
dgv8176n71 CNV Loss 21882294
nsv469605 CNV Complex 16826518
dgv8177n71 CNV Loss 21882294
dgv8178n71 CNV Gain+Loss 21882294

Relevant External Links for FAM74A1 Gene

HapMap Linkage Disequilibrium report
FAM74A1

Disorders for FAM74A1 Gene

No disorders were found for FAM74A1 Gene.

No data available for UniProtKB/Swiss-Prot for FAM74A1 Gene

Publications for FAM74A1 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM74A1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM74A1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM74A1
    • Block miRNA regulation of FAM74A1 using miScript Target Protectors

    Sources for FAM74A1 Gene

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