Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM74A1 Gene

Subcategory (RNA class) for FAM74A1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for FAM74A1 Gene

  • Family With Sequence Similarity 74 Member A1 2 3 5
  • Family With Sequence Similarity 74, Member A5 2 3
  • Family With Sequence Similarity 74, Member A1 2
  • FAM74A1 FAM74A2 4
  • FAM74A5 3

External Ids for FAM74A1 Gene

Previous HGNC Symbols for FAM74A1 Gene

  • FAM74A5

Previous GeneCards Identifiers for FAM74A1 Gene

  • GC09P039890

Summaries for FAM74A1 Gene

GeneCards Summary for FAM74A1 Gene

FAM74A1 (Family With Sequence Similarity 74 Member A1) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM74A1 Gene

Genomics for FAM74A1 Gene

Regulatory Elements for FAM74A1 Gene

Genomic Location for FAM74A1 Gene

39,371,065 bp from pter
39,376,916 bp from pter
5,852 bases
Plus strand

Genomic View for FAM74A1 Gene

Genes around FAM74A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM74A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM74A1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM74A1 Gene

Proteins for FAM74A1 Gene

  • Protein details for FAM74A1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM74A1/A2
    Protein Accession:
    Secondary Accessions:
    • A6NK17

    Protein attributes for FAM74A1 Gene

    127 amino acids
    Molecular mass:
    14779 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM74A1 Gene

Post-translational modifications for FAM74A1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM74A1 Gene

Domains & Families for FAM74A1 Gene

Protein Domains for FAM74A1 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM74 family.
  • Belongs to the FAM74 family.
genes like me logo Genes that share domains with FAM74A1: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for FAM74A1 Gene

Function for FAM74A1 Gene

Gene Ontology (GO) - Molecular Function for FAM74A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM74A1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM74A1 Gene

Localization for FAM74A1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM74A1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM74A1 gene
Compartment Confidence
nucleus 2
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
cytosol 1

Gene Ontology (GO) - Cellular Components for FAM74A1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FAM74A1: view

Pathways & Interactions for FAM74A1 Gene

SuperPathways for FAM74A1 Gene

No Data Available

Interacting Proteins for FAM74A1 Gene

Selected Interacting proteins: Q5RGS3-F74A1_HUMAN for FAM74A1 Gene via UniProtKB IID

Gene Ontology (GO) - Biological Process for FAM74A1 Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM74A1 Gene

Drugs & Compounds for FAM74A1 Gene

No Compound Related Data Available

Transcripts for FAM74A1 Gene

mRNA/cDNA for FAM74A1 Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM74A1 Gene

No ASD Table

Relevant External Links for FAM74A1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM74A1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM74A1 Gene

mRNA differential expression in normal tissues according to GTEx for FAM74A1 Gene

This gene is overexpressed in Testis (x29.6), Brain - Spinal cord (cervical c-1) (x6.0), Brain - Hippocampus (x4.9), Brain - Caudate (basal ganglia) (x4.3), Brain - Hypothalamus (x4.2), and Brain - Nucleus accumbens (basal ganglia) (x4.0).

NURSA nuclear receptor signaling pathways regulating expression of FAM74A1 Gene:


SOURCE GeneReport for Unigene cluster for FAM74A1 Gene:

genes like me logo Genes that share expression patterns with FAM74A1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM74A1 Gene

Orthologs for FAM74A1 Gene

Evolution for FAM74A1 Gene

Gene Tree for FAM74A1 (if available)
Gene Tree for FAM74A1 (if available)

No data available for Orthologs for FAM74A1 Gene

Paralogs for FAM74A1 Gene

(4) SIMAP similar genes for FAM74A1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM74A1: view

No data available for Paralogs for FAM74A1 Gene

Variants for FAM74A1 Gene

Sequence variations from dbSNP and Humsavar for FAM74A1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000104022 -- 39,372,088(+) CCATG(C/G)AAATG intron-variant
rs1001273443 -- 39,369,313(+) GATCA(C/G)TGTTT upstream-variant-2KB
rs10114904 -- 39,371,243(+) GAGAA(A/G)ATGTG nc-transcript-variant
rs1014474311 -- 39,369,418(+) AATTA(C/T)CACCC upstream-variant-2KB
rs1020217602 -- 39,369,442(+) GTTCA(C/T)AATCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM74A1 Gene

Variant ID Type Subtype PubMed ID
dgv12693n54 CNV loss 21841781
esv24325 CNV gain+loss 19812545
esv2837124 CNV deletion 24192839
esv3620475 CNV loss 21293372
esv3620476 CNV gain 21293372
esv3891672 CNV gain+loss 25118596
nsv1075628 CNV deletion 25765185
nsv1119198 CNV deletion 24896259
nsv1119578 CNV deletion 24896259
nsv1126889 CNV deletion 24896259
nsv1133724 CNV deletion 24896259
nsv1137632 CNV deletion 24896259
nsv1137635 CNV deletion 24896259
nsv1144261 CNV deletion 24896259
nsv1145210 CNV deletion 24896259
nsv428215 CNV gain+loss 18775914
nsv469632 CNV gain+loss 16826518
nsv469801 CNV gain 16826518
nsv614284 CNV loss 21841781
nsv831565 CNV gain+loss 17160897
nsv8450 CNV gain+loss 18304495
nsv972319 CNV duplication 23825009
nsv972324 CNV duplication 23825009
nsv972697 CNV duplication 23825009
nsv972712 CNV duplication 23825009
nsv982274 CNV duplication 23825009

Relevant External Links for FAM74A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM74A1 Gene

Disorders for FAM74A1 Gene

Relevant External Links for FAM74A1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM74A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM74A1 Gene

Publications for FAM74A1 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for FAM74A1 Gene

Sources for FAM74A1 Gene

Loading form....