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Aliases for FAM72D Gene

Aliases for FAM72D Gene

  • Family With Sequence Similarity 72 Member D 2 3 5
  • Family With Sequence Similarity 72, Member D 2 3
  • Gastric Cancer Up-Regulated Protein 2 3 4
  • GCUD2 3 4
  • Family With Sequence Similarity 72 Member 3
  • Gastric Cancer Up-Regulated-2 3

External Ids for FAM72D Gene

Previous GeneCards Identifiers for FAM72D Gene

  • GC01M142618
  • GC01M143896

Summaries for FAM72D Gene

GeneCards Summary for FAM72D Gene

FAM72D (Family With Sequence Similarity 72 Member D) is a Protein Coding gene. An important paralog of this gene is FAM72B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM72D Gene

Genomics for FAM72D Gene

Regulatory Elements for FAM72D Gene

Promoters for FAM72D Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM72D on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM72D Gene

145,093,798 bp from pter
145,112,696 bp from pter
18,899 bases
Plus strand

Genomic View for FAM72D Gene

Genes around FAM72D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM72D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM72D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM72D Gene

Proteins for FAM72D Gene

  • Protein details for FAM72D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM72D
    Protein Accession:

    Protein attributes for FAM72D Gene

    149 amino acids
    Molecular mass:
    16688 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM72D Gene

Proteomics data for FAM72D Gene at MOPED

Post-translational modifications for FAM72D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM72D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM72D Gene

Domains & Families for FAM72D Gene

Protein Domains for FAM72D Gene


Suggested Antigen Peptide Sequences for FAM72D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM72 family.
  • Belongs to the FAM72 family.
genes like me logo Genes that share domains with FAM72D: view

No data available for Gene Families for FAM72D Gene

Function for FAM72D Gene

Molecular function for FAM72D Gene

UniProtKB/Swiss-Prot Induction:
Up-regulated in gastric cancer.

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM72D Gene

Localization for FAM72D Gene

Subcellular locations from

Jensen Localization Image for FAM72D Gene COMPARTMENTS Subcellular localization image for FAM72D gene
Compartment Confidence
extracellular 2
cytosol 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FAM72D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with FAM72D: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM72D Gene

Pathways & Interactions for FAM72D Gene

SuperPathways for FAM72D Gene

No Data Available

Interacting Proteins for FAM72D Gene

Selected Interacting proteins: Q6L9T8-FA72D_HUMAN for FAM72D Gene via I2D

Gene Ontology (GO) - Biological Process for FAM72D Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM72D Gene

Drugs & Compounds for FAM72D Gene

No Compound Related Data Available

Transcripts for FAM72D Gene

mRNA/cDNA for FAM72D Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM72D Gene

Family with sequence similarity 72, member D:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM72D Gene

No ASD Table

Relevant External Links for FAM72D Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM72D Gene

mRNA expression in normal human tissues for FAM72D Gene

SOURCE GeneReport for Unigene cluster for FAM72D Gene Hs.535577

genes like me logo Genes that share expression patterns with FAM72D: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM72D Gene

Orthologs for FAM72D Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM72D Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM72A 36
  • 87 (a)
(Canis familiaris)
Mammalia -- 36
  • 78 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 83 (a)
(Mus musculus)
Mammalia Fam72a 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 82 (a)
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
(Gallus gallus)
Aves -- 36
  • 72 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 72 (a)
(Danio rerio)
Actinopterygii FAM72B 36
  • 62 (a)
Species with no ortholog for FAM72D:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM72D Gene

Gene Tree for FAM72D (if available)
Gene Tree for FAM72D (if available)

Paralogs for FAM72D Gene

Paralogs for FAM72D Gene

(3) SIMAP similar genes for FAM72D Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM72D: view

Variants for FAM72D Gene

Sequence variations from dbSNP and Humsavar for FAM72D Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs570798 -- 145,102,742(+) gagac(C/T)gagtt intron-variant
rs910733 -- 145,109,453(-) CTTTT(C/T)GTGTT intron-variant
rs910734 -- 145,109,416(-) CCCCA(C/T)CCCCA intron-variant
rs1134005 -- 145,103,021(+) TGTAG(A/C/G/T)TTATC reference, missense
rs1077771 -- 145,109,712(+) atact(C/G)tccag intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM72D Gene

Variant ID Type Subtype PubMed ID
esv27918 CNV Gain+Loss 19812545

Variation tolerance for FAM72D Gene

Gene Damage Index Score: 5.10; 69.10% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM72D Gene

Disorders for FAM72D Gene

Relevant External Links for FAM72D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM72D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM72D Gene

Publications for FAM72D Gene

  1. All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci. (PMID: 26206078) Kutzner A. … Heese K. (Genomics 2015) 2 3 67
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM72D Gene

Sources for FAM72D Gene