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Aliases for FAM72D Gene

Aliases for FAM72D Gene

  • Family With Sequence Similarity 72, Member D 2 3
  • Gastric Cancer Up-Regulated Protein 2 3 4
  • GCUD2 3 4
  • Family With Sequence Similarity 72 Member 3
  • Gastric Cancer Up-Regulated-2 3
  • Protein FAM72D 3

External Ids for FAM72D Gene

Previous GeneCards Identifiers for FAM72D Gene

  • GC01M142618
  • GC01M143896

Summaries for FAM72D Gene

GeneCards Summary for FAM72D Gene

FAM72D (Family With Sequence Similarity 72, Member D) is a Protein Coding gene. An important paralog of this gene is FAM72B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM72D Gene

Genomics for FAM72D Gene

Regulatory Elements for FAM72D Gene

Genomic Location for FAM72D Gene

Start:
145,096,000 bp from pter
End:
145,112,696 bp from pter
Size:
16,697 bases
Orientation:
Plus strand

Genomic View for FAM72D Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM72D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM72D Gene

Proteins for FAM72D Gene

  • Protein details for FAM72D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6L9T8-FA72D_HUMAN
    Recommended name:
    Protein FAM72D
    Protein Accession:
    Q6L9T8
    Secondary Accessions:

    Protein attributes for FAM72D Gene

    Size:
    149 amino acids
    Molecular mass:
    16688 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM72D Gene

Proteomics data for FAM72D Gene at MOPED

Post-translational modifications for FAM72D Gene

Other Protein References for FAM72D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM72D Gene

Domains for FAM72D Gene

Protein Domains for FAM72D Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM72D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6L9T8

UniProtKB/Swiss-Prot:

FA72D_HUMAN :
  • Q6L9T8
Family:
  • Belongs to the FAM72 family.
genes like me logo Genes that share domains with FAM72D: view

No data available for Gene Families for FAM72D Gene

Function for FAM72D Gene

Molecular function for FAM72D Gene

UniProtKB/Swiss-Prot Induction: Up-regulated in gastric cancer

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM72D Gene

Localization for FAM72D Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM72D Gene COMPARTMENTS Subcellular localization image for FAM72D gene
Compartment Confidence
extracellular 2
cytosol 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM72D Gene

Pathways for FAM72D Gene

SuperPathways for FAM72D Gene

No Data Available

Interacting Proteins for FAM72D Gene

Selected Interacting proteins: Q6L9T8-FA72D_HUMAN for FAM72D Gene via I2D

Gene Ontology (GO) - Biological Process for FAM72D Gene

None

No data available for Pathways by source for FAM72D Gene

Transcripts for FAM72D Gene

mRNA/cDNA for FAM72D Gene

(2) Additional mRNA sequences :
(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM72D Gene

Family with sequence similarity 72, member D:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM72D

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM72D Gene

No ASD Table

Relevant External Links for FAM72D Gene

GeneLoc Exon Structure for
FAM72D
ECgene alternative splicing isoforms for
FAM72D

Expression for FAM72D Gene

mRNA expression in normal human tissues for FAM72D Gene

SOURCE GeneReport for Unigene cluster for FAM72D Gene Hs.535577

genes like me logo Genes that share expressions with FAM72D: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for FAM72D Gene

Orthologs for FAM72D Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM72D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
OneToMany
cow
(Bos Taurus)
Mammalia FAM72A 36
  • 87 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 78 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Fam72a 36
  • 89 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 83 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 82 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 72 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 72 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii FAM72B 36
  • 62 (a)
OneToMany
Species with no ortholog for FAM72D:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM72D Gene

ENSEMBL:
Gene Tree for FAM72D (if available)
TreeFam:
Gene Tree for FAM72D (if available)

Paralogs for FAM72D Gene

Paralogs for FAM72D Gene

Selected SIMAP similar genes for FAM72D Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM72D: view

Variants for FAM72D Gene

Sequence variations from dbSNP and Humsavar for FAM72D Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs2095827 -- 145,105,534(-) cacca(C/T)gccca intron-variant
rs2185180 -- 145,101,614(-) ttgtt(C/G)tcaca intron-variant
rs9697686 -- 145,100,797(+) caccc(A/G)gctaa intron-variant
rs61824251 -- 145,105,882(-) CTCCG(C/T)CTCCC intron-variant
rs61824255 -- 145,100,825(-) AATCC(C/T)GTCTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM72D Gene

Variant ID Type Subtype PubMed ID
esv27918 CNV Gain+Loss 19812545

Relevant External Links for FAM72D Gene

HapMap Linkage Disequilibrium report
FAM72D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM72D Gene

Disorders for FAM72D Gene

No disorders were found for FAM72D Gene.

No data available for UniProtKB/Swiss-Prot for FAM72D Gene

Publications for FAM72D Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3

Products for FAM72D Gene

Sources for FAM72D Gene

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