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FAM72C Gene(Protein Coding)

Family With Sequence Similarity 72 Member C

GCID:
GC01M143956
GIFtS:
29
Genes Participants
UDN Logo

Aliases for FAM72C Gene

Aliases for FAM72C Gene

  • Family With Sequence Similarity 72 Member C 2 3 5
  • Family With Sequence Similarity 72, Member C 2
  • Protein FAM72C 3
  • RP5-998N21.9 3

External Ids for FAM72C Gene

Previous GeneCards Identifiers for FAM72C Gene

  • GC01U901175
  • GC01M149438
  • GC01M143944

Summaries for FAM72C Gene

GeneCards Summary for FAM72C Gene

FAM72C (Family With Sequence Similarity 72 Member C) is a Protein Coding gene. An important paralog of this gene is FAM72D.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM72C Gene

Genomics for FAM72C Gene

Products:

  1. Regulatory Element

Regulatory Elements for FAM72C Gene

Enhancers for FAM72C Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G143988 0.9 Ensembl 0.4 -15.3 -15296 1.8 PKNOX1 INSM2 KLF17 FEZF1 ZNF2 ZEB1 ZNF366 ZSCAN5C ZNF680 CEBPB FAM72C GC01P144021
GH01G144009 0.7 Ensembl ENCODE 0.3 -35.7 -35696 1.0 PKNOX1 IKZF1 TBX21 GC01P144021 FAM72C
GH01G144014 0.5 Ensembl 0.3 -41.1 -41096 2.6 LEF1 FOXK2 PBX2 NR2C1 ZNF592 GC01P144021 FAM72C
GH01G144019 0.4 Ensembl 0.2 -45.9 -45896 1.4 SRF PRDM6 GC01P144021 FAM72C
GH01G144002 0.2 Ensembl 0.3 -28.2 -28197 0.4 GC01P144021 FAM72C
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM72C on UCSC Golden Path with GeneCards custom track

Promoters for FAM72C Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000012700 1105 4201 HDGF PKNOX1 ATF1 SIN3A TCF12 GLIS2 ZNF143 FOS SP3 NFYC

Genomic Location for FAM72C Gene

Chromosome:
1
Start:
143,955,364 bp from pter
End:
143,974,205 bp from pter
Size:
18,842 bases
Orientation:
Minus strand

Genomic View for FAM72C Gene

Genes around FAM72C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM72C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM72C Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for FAM72C Gene

Proteins for FAM72C Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for FAM72C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    H0Y354-FA72C_HUMAN
    Recommended name:
    Protein FAM72C
    Protein Accession:
    H0Y354

    Protein attributes for FAM72C Gene

    Size:
    149 amino acids
    Molecular mass:
    16730 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM72C Gene

Post-translational modifications for FAM72C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM72C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM72C Gene

Domains & Families for FAM72C Gene

Protein Domains for FAM72C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM72C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

H0Y354

UniProtKB/Swiss-Prot:

FA72C_HUMAN :
  • Belongs to the FAM72 family.
Family:
  • Belongs to the FAM72 family.
genes like me logo Genes that share domains with FAM72C: view

No data available for Gene Families for FAM72C Gene

Function for FAM72C Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM72C Gene

Localization for FAM72C Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM72C gene
Compartment Confidence
extracellular 3
plasma membrane 1

Gene Ontology (GO) - Cellular Components for FAM72C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol IDA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with FAM72C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM72C Gene

Pathways & Interactions for FAM72C Gene

SuperPathways for FAM72C Gene

PathCards logo More details on SuperPathways for FAM72C
No Data Available

Interacting Proteins for FAM72C Gene

Gene Ontology (GO) - Biological Process for FAM72C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM72C Gene

Drugs & Compounds for FAM72C Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for FAM72C Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for FAM72C Gene

(8) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM72C Gene

Family with sequence similarity 72, member C:
Representative Sequences:

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM72C Gene

No ASD Table

Relevant External Links for FAM72C Gene

GeneLoc Exon Structure for
FAM72C
ECgene alternative splicing isoforms for
FAM72C

Expression for FAM72C Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM72C Gene

mRNA expression in normal human tissues for FAM72C Gene
mRNA expression by GTEx for FAM72C Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM72C Gene:

FAM72C

SOURCE GeneReport for Unigene cluster for FAM72C Gene:

Hs.568238
genes like me logo Genes that share expression patterns with FAM72C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM72C Gene

Orthologs for FAM72C Gene

Evolution for FAM72C Gene

ENSEMBL:
Gene Tree for FAM72C (if available)
TreeFam:
Gene Tree for FAM72C (if available)

No data available for Orthologs for FAM72C Gene

Paralogs for FAM72C Gene

Paralogs for FAM72C Gene

(3) SIMAP similar genes for FAM72C Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM72C: view

Variants for FAM72C Gene

Sequence variations from dbSNP and Humsavar for FAM72C Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10718 -- 143,955,516(+) TTTGT(A/G)GCTCT nc-transcript-variant, utr-variant-3-prime
rs1321214 -- 143,955,031(+) GTATC(C/G)CGGCT downstream-variant-500B
rs1338870 -- 143,955,645(+) CAGAC(C/T)ACTCG nc-transcript-variant, utr-variant-3-prime
rs139024480 -- 143,958,249(+) ATTTC(A/G)TTCAT intron-variant
rs140925069 -- 143,963,522(+) AAGTA(C/G)TAACA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM72C Gene

Variant ID Type Subtype PubMed ID
dgv380n100 CNV gain+loss 25217958
dgv381n100 CNV gain 25217958
dgv383n100 CNV loss 25217958
dgv397n100 CNV loss 25217958
esv21838 CNV gain+loss 19812545
esv26241 CNV gain+loss 19812545
esv3894067 CNV gain 25118596
esv3894156 CNV loss 25118596
esv3894189 CNV gain+loss 25118596
nsv1128610 CNV duplication 24896259
nsv1139490 CNV duplication 24896259
nsv1148298 CNV duplication 26484159
nsv831237 CNV gain 17160897
nsv946195 CNV duplication 23825009
nsv946220 CNV duplication 23825009
nsv946367 CNV duplication 23825009

Relevant External Links for FAM72C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM72C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM72C Gene

Disorders for FAM72C Gene

Relevant External Links for FAM72C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM72C

No disorders were found for FAM72C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM72C Gene

Publications for FAM72C Gene

  1. All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci. (PMID: 26206078) Kutzner A. … Heese K. (Genomics 2015) 2 3 64
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64

Products for FAM72C Gene

Sources for FAM72C Gene

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