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Aliases for FAM72B Gene

Aliases for FAM72B Gene

  • Family With Sequence Similarity 72, Member B 2 3
  • Amyloid-Beta Peptide-Induced Protein P17 3
  • Protein FAM72B 3
  • RP11-439A17.6 3
  • P17 3

External Ids for FAM72B Gene

Previous GeneCards Identifiers for FAM72B Gene

  • GC01U901174
  • GC01P120641
  • GC01P120837

Summaries for FAM72B Gene

GeneCards Summary for FAM72B Gene

FAM72B (Family With Sequence Similarity 72, Member B) is a Protein Coding gene. An important paralog of this gene is FAM72A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM72B Gene

Genomics for FAM72B Gene

Regulatory Elements for FAM72B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM72B Gene

121,167,646 bp from pter
121,185,539 bp from pter
17,894 bases
Minus strand

Genomic View for FAM72B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM72B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM72B Gene

Proteins for FAM72B Gene

  • Protein details for FAM72B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM72B
    Protein Accession:
    Secondary Accessions:
    • B2RPQ5
    • Q5QP15

    Protein attributes for FAM72B Gene

    149 amino acids
    Molecular mass:
    16617 Da
    Quaternary structure:
    No Data Available
    • Highly homologous to GCUD2 but localized to a distinct locus

    Alternative splice isoforms for FAM72B Gene


neXtProt entry for FAM72B Gene

Proteomics data for FAM72B Gene at MOPED

Post-translational modifications for FAM72B Gene

Other Protein References for FAM72B Gene

No data available for DME Specific Peptides for FAM72B Gene

Domains for FAM72B Gene

Protein Domains for FAM72B Gene


Suggested Antigen Peptide Sequences for FAM72B Gene

Graphical View of Domain Structure for InterPro Entry



  • Q86X60
  • Belongs to the FAM72 family.
genes like me logo Genes that share domains with FAM72B: view

No data available for Gene Families for FAM72B Gene

Function for FAM72B Gene

Phenotypes for FAM72B Gene

GenomeRNAi human phenotypes for FAM72B:
genes like me logo Genes that share phenotypes with FAM72B: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM72B Gene

Localization for FAM72B Gene

Subcellular locations from

Jensen Localization Image for FAM72B Gene COMPARTMENTS Subcellular localization image for FAM72B gene
Compartment Confidence
extracellular 2
cytosol 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM72B Gene

Pathways for FAM72B Gene

SuperPathways for FAM72B Gene

No Data Available

Interacting Proteins for FAM72B Gene

Gene Ontology (GO) - Biological Process for FAM72B Gene


No data available for Pathways by source for FAM72B Gene

Transcripts for FAM72B Gene

mRNA/cDNA for FAM72B Gene

(3) Additional mRNA sequences :
(4) REFSEQ mRNAs :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM72B Gene

Family with sequence similarity 72, member B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM72B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM72B Gene

No ASD Table

Relevant External Links for FAM72B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM72B Gene

mRNA expression in normal human tissues for FAM72B Gene

SOURCE GeneReport for Unigene cluster for FAM72B Gene Hs.339665

genes like me logo Genes that share expressions with FAM72B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for FAM72B Gene

Orthologs for FAM72B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM72B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM72A 36
  • 88 (a)
(Canis familiaris)
Mammalia -- 36
  • 78 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 83 (a)
(Mus musculus)
Mammalia Fam72a 36
  • 89 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 82 (a)
(Pan troglodytes)
Mammalia -- 36
  • 99 (a)
(Gallus gallus)
Aves -- 36
  • 72 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 72 (a)
(Danio rerio)
Actinopterygii FAM72B 36
  • 63 (a)
Species with no ortholog for FAM72B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM72B Gene

Gene Tree for FAM72B (if available)
Gene Tree for FAM72B (if available)

Paralogs for FAM72B Gene

Paralogs for FAM72B Gene

Selected SIMAP similar genes for FAM72B Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM72B: view

Variants for FAM72B Gene

Sequence variations from dbSNP and Humsavar for FAM72B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs566211 -- 121,177,739(-) agatg(C/G)ggttt intron-variant
rs1260179 -- 121,173,458(+) ataga(C/T)actgg intron-variant
rs1578065 -- 121,175,946(+) AAATG(A/G)CATCA intron-variant
rs1578066 -- 121,176,247(+) tcact(G/T)cagcc intron-variant
rs2185178 -- 121,177,804(+) TTGGC(C/T)TCCCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM72B Gene

Variant ID Type Subtype PubMed ID
nsv524681 CNV Gain 19592680
dgv94e1 CNV Complex 17122850
dgv97e1 CNV Complex 17122850
nsv872181 CNV Gain 21882294
dgv336n71 CNV Gain 21882294
esv26241 CNV Gain+Loss 19812545
dgv337n71 CNV Gain 21882294
nsv831237 CNV Gain 17160897
dgv338n71 CNV Gain 21882294
nsv872191 CNV Gain 21882294

Relevant External Links for FAM72B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM72B Gene

Disorders for FAM72B Gene

No disorders were found for FAM72B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for FAM72B Gene

Publications for FAM72B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Identification and characterisation of the novel amyloid-beta peptide-induced protein p17. (PMID: 19755123) Nehar S. … Heese K. (FEBS Lett. 2009) 3
  3. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PMID: 22505724) Udeshi N.D. … Carr S.A. (Mol. Cell Proteomics 2012) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4

Products for FAM72B Gene

Sources for FAM72B Gene

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