Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM71F2 Gene

Aliases for FAM71F2 Gene

  • Family With Sequence Similarity 71 Member F2 2 3 5
  • Family With Sequence Similarity 137, Member B 2 3
  • FAM137B 3 4
  • Family With Sequence Similarity 71, Member F2 2
  • Protein FAM71F2 3
  • Protein FAM137B 4

External Ids for FAM71F2 Gene

Previous HGNC Symbols for FAM71F2 Gene

  • FAM137B

Previous GeneCards Identifiers for FAM71F2 Gene

  • GC07P128101
  • GC07P128312
  • GC07P122672
  • GC07P128672
  • GC07P128712
  • GC07P128741
  • GC07P128779
  • GC07P128811
  • GC07P128838

Summaries for FAM71F2 Gene

GeneCards Summary for FAM71F2 Gene

FAM71F2 (Family With Sequence Similarity 71 Member F2) is a Protein Coding gene. An important paralog of this gene is FAM71F1.

Additional gene information for FAM71F2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM71F2 Gene

Genomics for FAM71F2 Gene

Regulatory Elements for FAM71F2 Gene


Enhancers around FAM71F2 on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM71F2 Gene

Chromosome:
7
Start:
128,671,636 bp from pter
End:
128,702,262 bp from pter
Size:
30,627 bases
Orientation:
Plus strand

Genomic View for FAM71F2 Gene

Genes around FAM71F2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM71F2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM71F2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM71F2 Gene

Proteins for FAM71F2 Gene

  • Protein details for FAM71F2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NXP2-F71F2_HUMAN
    Recommended name:
    Protein FAM71F2
    Protein Accession:
    Q6NXP2
    Secondary Accessions:
    • Q0VGF6
    • Q0VGF7
    • Q86X39

    Protein attributes for FAM71F2 Gene

    Size:
    309 amino acids
    Molecular mass:
    34516 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM71F2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM71F2 Gene

Post-translational modifications for FAM71F2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM71F2 Gene

Domains & Families for FAM71F2 Gene

Gene Families for FAM71F2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM71F2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM71F2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6NXP2

UniProtKB/Swiss-Prot:

F71F2_HUMAN :
  • Belongs to the FAM71 family.
Family:
  • Belongs to the FAM71 family.
genes like me logo Genes that share domains with FAM71F2: view

Function for FAM71F2 Gene

Phenotypes for FAM71F2 Gene

GenomeRNAi human phenotypes for FAM71F2:
genes like me logo Genes that share phenotypes with FAM71F2: view

Animal Model Products

CRISPR Products

miRNA for FAM71F2 Gene

miRTarBase miRNAs that target FAM71F2

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM71F2 Gene

Localization for FAM71F2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM71F2 gene
Compartment Confidence
nucleus 4
cytoskeleton 2
plasma membrane 1
peroxisome 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for FAM71F2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with FAM71F2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM71F2 Gene

Pathways & Interactions for FAM71F2 Gene

SuperPathways for FAM71F2 Gene

No Data Available

Interacting Proteins for FAM71F2 Gene

Gene Ontology (GO) - Biological Process for FAM71F2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM71F2 Gene

Drugs & Compounds for FAM71F2 Gene

No Compound Related Data Available

Transcripts for FAM71F2 Gene

Unigene Clusters for FAM71F2 Gene

Family with sequence similarity 71, member F2:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM71F2 Gene

No ASD Table

Relevant External Links for FAM71F2 Gene

GeneLoc Exon Structure for
FAM71F2
ECgene alternative splicing isoforms for
FAM71F2

Expression for FAM71F2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM71F2 Gene

mRNA differential expression in normal tissues according to GTEx for FAM71F2 Gene

This gene is overexpressed in Testis (x11.0).

NURSA nuclear receptor signaling pathways regulating expression of FAM71F2 Gene:

FAM71F2

SOURCE GeneReport for Unigene cluster for FAM71F2 Gene:

Hs.445236

Evidence on tissue expression from TISSUES for FAM71F2 Gene

  • Nervous system(4)
genes like me logo Genes that share expression patterns with FAM71F2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM71F2 Gene

Orthologs for FAM71F2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for FAM71F2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM71F2 33 34
  • 99.03 (n)
dog
(Canis familiaris)
Mammalia FAM71F2 33 34
  • 86.51 (n)
rat
(Rattus norvegicus)
Mammalia Fam71f2 33
  • 82.88 (n)
mouse
(Mus musculus)
Mammalia Fam71f2 33 16 34
  • 82.32 (n)
cow
(Bos Taurus)
Mammalia FAM71F2 33 34
  • 81.71 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 55 (a)
OneToMany
-- 34
  • 47 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 31 (a)
OneToMany
Species where no ortholog for FAM71F2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM71F2 Gene

ENSEMBL:
Gene Tree for FAM71F2 (if available)
TreeFam:
Gene Tree for FAM71F2 (if available)

Paralogs for FAM71F2 Gene

(1) SIMAP similar genes for FAM71F2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM71F2: view

Variants for FAM71F2 Gene

Sequence variations from dbSNP and Humsavar for FAM71F2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000064770 -- 128,700,886(+) TGCTG(A/G)AAACA intron-variant
rs1000072266 -- 128,681,411(+) TCTCG(-/TTTC)TTTCT intron-variant
rs1000241607 -- 128,694,053(+) AATGG(C/T)AGGCC intron-variant
rs1000255953 -- 128,687,976(+) CTCTA(C/T)GAGAC intron-variant, downstream-variant-500B
rs1000263853 -- 128,700,425(+) ACAGG(C/T)ATGCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM71F2 Gene

Variant ID Type Subtype PubMed ID
esv2670312 CNV deletion 23128226
esv2735137 CNV deletion 23290073

Variation tolerance for FAM71F2 Gene

Residual Variation Intolerance Score: 88.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 20.58; 99.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM71F2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM71F2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM71F2 Gene

Disorders for FAM71F2 Gene

Relevant External Links for FAM71F2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM71F2

No disorders were found for FAM71F2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM71F2 Gene

Publications for FAM71F2 Gene

  1. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  4. Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PMID: 17672918) Szafranski K … Platzer M (Genome biology 2007) 3 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60

Products for FAM71F2 Gene

Sources for FAM71F2 Gene

Content
Loading form....