Aliases for FAM71E1 Gene
Aliases for FAM71E1 Gene
External Ids for FAM71E1 Gene
- HGNC: 25107
- Entrez Gene: 112703
- Ensembl: ENSG00000142530
- UniProtKB: Q6IPT2
Previous GeneCards Identifiers for FAM71E1 Gene
- GC19M055662
- GC19M050970
- GC19M047307
Summaries for FAM71E1 Gene
GeneCards Summary for FAM71E1 Gene
FAM71E1 (Family With Sequence Similarity 71 Member E1) is a Protein Coding gene. An important paralog of this gene is FAM71A.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM71E1 Gene
Genomics for FAM71E1 Gene
Regulatory Elements for FAM71E1 Gene
Enhancers for FAM71E1 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH19G050346 | 1.2 | Ensembl ENCODE | 11.1 | +128.7 | 128724 | 3.9 | PKNOX1 ATF1 FOXA2 ARID4B DMAP1 ZNF48 ZNF143 JUNB MIER2 TBX21 | NAPSB KCNC3 NAPSA POLD1 JOSD2 ASPDH EMC10 FAM71E1 KLK2 ENSG00000269392 |
| GH19G050410 | 0.7 | ENCODE | 11.7 | +65.8 | 65803 | 1.3 | CTCF CHD4 ZMYM3 ZNF384 ZNF488 ZNF48 TBX3 ZNF366 POLR2A SMARCA4 | NAPSB NAPSA NR1H2 FAM71E1 EMC10 ENSG00000142539 GC19P050397 |
| GH19G050465 | 1.1 | Ensembl ENCODE | 6.3 | +10.3 | 10262 | 2.4 | SIN3A RAD21 ZNF48 ZNF366 EGR1 ZNF143 FOS CREM EGR2 ZBTB11 | ASPDH FAM71E1 EMC10 MYBPC2 |
| GH19G050479 | 1.1 | ENCODE dbSUPER | 0.7 | -2.8 | -2758 | 0.7 | ELF3 HDGF PKNOX1 CBX3 RB1 ARID4B SIN3A RAD21 ZNF2 ZNF48 | NAPSA NR1H2 CLEC11A LOC100506114 FAM71E1 GC19P050481 |
| GH19G050475 | 1.1 | ENCODE | 0.7 | +0.3 | 291 | 2.2 | HDGF PKNOX1 CREB3L1 SIN3A ZNF2 YY1 ZNF207 ZNF143 FOS ZNF263 | ASPDH FAM71E1 EMC10 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM71E1 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM71E1 gene promoter:
Regulatory Element Products
Genomic Location for FAM71E1 Gene
- Chromosome:
- 19
- Start:
- 50,466,643 bp from pter
- End:
- 50,476,753 bp from pter
- Size:
- 10,111 bases
- Orientation:
- Minus strand
Genomic View for FAM71E1 Gene
Genes around FAM71E1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by Ensembl
- 19q13.33 by Entrez Gene
- 19q13.33 by HGNC
FAM71E1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM71E1 Gene
Proteins for FAM71E1 Gene
-
Protein details for FAM71E1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6IPT2-F71E1_HUMAN
- Recommended name:
- Protein FAM71E1
- Protein Accession:
- Q6IPT2
- Q96EJ5
- Q9BSM9
Protein attributes for FAM71E1 Gene
- Size:
- 247 amino acids
- Molecular mass:
- 27609 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM71E1 Gene
Post-translational modifications for FAM71E1 Gene
Other Protein References for FAM71E1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Protein Products
-
OriGene Purified Proteins for FAM71E1
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM71E1
- Origene Custom Protein Services for FAM71E1
- Novus Biologicals lysates for FAM71E1
- Search GeneTex for Proteins for FAM71E1
Assay Products
No data available for DME Specific Peptides for FAM71E1 Gene
Domains & Families for FAM71E1 Gene
Suggested Antigen Peptide Sequences for FAM71E1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q6IPT2- Family:
-
- Belongs to the FAM71 family.
No data available for Gene Families for FAM71E1 Gene
Function for FAM71E1 Gene
Phenotypes for FAM71E1 Gene
- GenomeRNAi human phenotypes for FAM71E1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM71E1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71E1 gene
- Search ViGene Biosciences for FAM71E1
CRISPR Products
-
OriGene CRISPR knockouts for FAM71E1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM71E1
- GenScript: Design CRISPR guide RNA sequences for FAM71E1
miRNA for FAM71E1 Gene
- miRTarBase miRNAs that target FAM71E1
miRNA Products
- Search ViGene Biosciences for FAM71E1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM71E1
- Browse OriGene Inhibitory RNA Products For FAM71E1
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71E1 gene
Clone Products
-
OriGene ORF clones in human for FAM71E1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM71E1
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM71E1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM71E1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71E1 gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM71E1 Gene
Localization for FAM71E1 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM71E1 Gene
Transcripts for FAM71E1 Gene
mRNA/cDNA for FAM71E1 Gene
- (4) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM71E1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM71E1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM71E1
- GenScript: Design CRISPR guide RNA sequences for FAM71E1
miRNA Products
- Search ViGene Biosciences for FAM71E1
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM71E1
- Browse OriGene Inhibitory RNA Products For FAM71E1
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71E1 gene
Clone Products
-
OriGene ORF clones in human for FAM71E1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM71E1 Gene
mRNA differential expression in normal tissues according to GTEx for FAM71E1 Gene
This gene is overexpressed in Testis (x24.6).
This gene is overexpressed in Urine (66.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM71E1 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of FAM71E1 Gene:
FAM71E1SOURCE GeneReport for Unigene cluster for FAM71E1 Gene:
Hs.448941Evidence on tissue expression from TISSUES for FAM71E1 Gene
- Nervous system(4.1)
- Pancreas(4)
Primer Products
-
OriGene qPCR primer pairs for FAM71E1
-
OriGene qPCR primer pairs and template standards for FAM71E1
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM71E1 Gene
Orthologs for FAM71E1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM71E1 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM71E1 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM71E1 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam71e1 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam71e1 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM71E1 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FAM71E1 35 |
|
OneToOne |
- Species where no ortholog for FAM71E1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM71E1 Gene
Variants for FAM71E1 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000417345 | -- | 50,470,242(+) | TGCAC(A/G)GTGGC | intron-variant | |
| rs1000510696 | -- | 50,470,462(+) | GAGCC(A/G)AGATC | intron-variant | |
| rs1000803983 | -- | 50,474,464(+) | CCTCA(C/G)CCTCC | intron-variant | |
| rs1000897156 | -- | 50,472,635(+) | CACAC(A/G)TATAG | intron-variant | |
| rs1001182839 | -- | 50,478,010(+) | AGTCA(A/G)GCAAC | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2718736 | CNV | deletion | 23290073 |
| nsv1125677 | CNV | tandem duplication | 24896259 |
| nsv1127694 | CNV | deletion | 24896259 |
| nsv1133010 | OTHER | inversion | 24896259 |
| nsv1140251 | OTHER | inversion | 24896259 |
| nsv1152956 | OTHER | inversion | 26484159 |
| nsv509750 | CNV | insertion | 20534489 |
Residual Variation Intolerance Score:
71.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.38;
42.19% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM71E1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM71E1
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM71E1 Gene
Disorders for FAM71E1 Gene
Relevant External Links for FAM71E1
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM71E1
No disorders were found for FAM71E1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM71E1 Gene
Publications for FAM71E1 Gene
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
Products for FAM71E1 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
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- Browse OriGene Antibodies
- Custom Antibody Services
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- Custom Assay Services
- OriGene Purified Proteins for FAM71E1
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM71E1
- Origene Custom Protein Services for FAM71E1
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM71E1
- Browse OriGene Inhibitory RNA Products For FAM71E1
- OriGene qPCR primer pairs and template standards for FAM71E1
- OriGene qPCR primer pairs for FAM71E1
- OriGene CRISPR knockouts for FAM71E1
- OriGene ORF clones in human for FAM71E1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FAM71E1
- GenScript: Next-day shipping cDNA ORF clone for FAM71E1 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM71E1
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- GenScript: Design CRISPR guide RNA sequences for FAM71E1
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
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- Browse Sino Biological cDNA Clones
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- Sino Biological Antibodies
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- Sino Biological Cell Lysates
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- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals lysates for FAM71E1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for FAM71E1 gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM71E1 gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM71E1 gene
- Search ViGene Biosciences for FAM71E1
- Horizon Cell Lines for FAM71E1
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM71E1
- VectorBuilder custom plasmid, inducible vectors for FAM71E1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM71E1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM71E1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer