Aliases for FAM71D Gene
Aliases for FAM71D Gene
External Ids for FAM71D Gene
- HGNC: 20101
- Entrez Gene: 161142
- Ensembl: ENSG00000172717
- UniProtKB: Q8N9W8
Previous HGNC Symbols for FAM71D Gene
- C14orf54
Previous GeneCards Identifiers for FAM71D Gene
- GC14P066726
- GC14P067656
- GC14P047825
Summaries for FAM71D Gene
GeneCards Summary for FAM71D Gene
FAM71D (Family With Sequence Similarity 71 Member D) is a Protein Coding gene. An important paralog of this gene is FAM71B.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM71D Gene
Genomics for FAM71D Gene
Regulatory Elements for FAM71D Gene
Regulatory Element Products
Genomic Location for FAM71D Gene
- Chromosome:
- 14
- Start:
- 67,189,393 bp from pter
- End:
- 67,228,550 bp from pter
- Size:
- 39,158 bases
- Orientation:
- Plus strand
Genomic View for FAM71D Gene
Genes around FAM71D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q23.3 by Ensembl
- 14q23.3 by Entrez Gene
- 14q23.3 by HGNC
FAM71D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM71D Gene
Proteins for FAM71D Gene
-
Protein details for FAM71D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N9W8-FA71D_HUMAN
- Recommended name:
- Protein FAM71D
- Protein Accession:
- Q8N9W8
- Q86VN4
Protein attributes for FAM71D Gene
- Size:
- 422 amino acids
- Molecular mass:
- 47076 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM71D Gene
Post-translational modifications for FAM71D Gene
Other Protein References for FAM71D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for FAM71D
-
Abcam antibodies for FAM71D
- GeneTex FAM71D antibody for FAM71D
Protein Products
-
OriGene Purified Proteins for FAM71D
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM71D
- Origene Custom Protein Services for FAM71D
- Novus Biologicals lysates for FAM71D
- Search GeneTex for Proteins for FAM71D
Assay Products
No data available for DME Specific Peptides for FAM71D Gene
Domains & Families for FAM71D Gene
Suggested Antigen Peptide Sequences for FAM71D Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8N9W8- Family:
-
- Belongs to the FAM71 family.
No data available for Gene Families for FAM71D Gene
Function for FAM71D Gene
Phenotypes for FAM71D Gene
- GenomeRNAi human phenotypes for FAM71D:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM71D gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71D gene
- Search ViGene Biosciences for FAM71D
CRISPR Products
-
OriGene CRISPR knockouts for FAM71D
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM71D
miRNA Products
- Search ViGene Biosciences for FAM71D
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM71D
- Browse OriGene Inhibitory RNA Products For FAM71D
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71D gene
Clone Products
-
OriGene ORF clones in human for FAM71D
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM71D
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM71D gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM71D gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71D gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM71D Gene
Localization for FAM71D Gene
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM71D Gene
Pathways & Interactions for FAM71D Gene
No data available for Pathways by source and SIGNOR curated interactions for FAM71D Gene
Transcripts for FAM71D Gene
mRNA/cDNA for FAM71D Gene
- (4) REFSEQ mRNAs :
- (4) Additional mRNA sequences :
- (20) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM71D Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM71D
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM71D
miRNA Products
- Search ViGene Biosciences for FAM71D
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for FAM71D
- Browse OriGene Inhibitory RNA Products For FAM71D
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71D gene
Clone Products
-
OriGene ORF clones in human for FAM71D
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: |
Expression for FAM71D Gene
mRNA differential expression in normal tissues according to GTEx for FAM71D Gene
This gene is overexpressed in Testis (x36.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM71D Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM71D Gene:
FAM71DSOURCE GeneReport for Unigene cluster for FAM71D Gene:
Hs.412818Evidence on tissue expression from TISSUES for FAM71D Gene
- Nervous system(4.1)
Primer Products
-
OriGene qPCR primer pairs for FAM71D
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM71D Gene
Orthologs for FAM71D Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM71D 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | FAM71D 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | FAM71D 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Fam71d 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Fam71d 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FAM71D 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FAM71D 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FAM71D 35 |
|
OneToOne |
- Species where no ortholog for FAM71D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM71D Gene
Paralogs for FAM71D Gene
(1) SIMAP similar genes for FAM71D Gene using alignment to 7 proteins:
Variants for FAM71D Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000152798 | -- | 67,224,715(+) | GAGAT(C/T)CAAGA | intron-variant | |
| rs1000245495 | -- | 67,211,997(+) | TCTGC(A/C)AGGAG | intron-variant | |
| rs1000267006 | -- | 67,200,952(+) | TGTCT(G/T)TGGCA | intron-variant | |
| rs1000308030 | -- | 67,209,853(+) | AAGTA(A/T)AATAG | intron-variant | |
| rs1000310251 | -- | 67,207,780(+) | TTGAC(-/A)AAAAA | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2751285 | CNV | gain | 17911159 |
| esv3581255 | CNV | loss | 25503493 |
| nsv1124992 | CNV | deletion | 24896259 |
| nsv832821 | CNV | gain | 17160897 |
| nsv977480 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
23.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.80;
66.89% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM71D Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FAM71D
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM71D Gene
Disorders for FAM71D Gene
Relevant External Links for FAM71D
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM71D
No disorders were found for FAM71D Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM71D Gene
Publications for FAM71D Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Next-generation sequencing reveals novel rare fusion events with functional implication in prostate cancer. (PMID: 24488012) Teles Alves I. … Jenster G. (Oncogene 2015) 3 64
- The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. (PMID: 25277244) Katsogiannou M. … Rocchi P. (Mol. Cell Proteomics 2014) 3 64
- Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 64
Products for FAM71D Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for FAM71D
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FAM71D
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM71D
- Origene Custom Protein Services for FAM71D
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM71D
- Browse OriGene Inhibitory RNA Products For FAM71D
- OriGene qPCR primer pairs for FAM71D
- OriGene CRISPR knockouts for FAM71D
- OriGene ORF clones in human for FAM71D
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FAM71D
- GenScript: Next-day shipping cDNA ORF clone for FAM71D in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM71D
- GenScript Custom Assay Services for FAM71D
- GenScript Custom overexpressing Cell Line Services for FAM71D
- Browse GenScript CRISPR for FAM71D
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM71D
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals lysates for FAM71D
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for FAM71D gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM71D gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM71D gene
- Search ViGene Biosciences for FAM71D
- Horizon Cell Lines for FAM71D
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM71D
- VectorBuilder custom plasmid, inducible vectors for FAM71D
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM71D
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM71D Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer