FAM71D Gene
protein-coding GIFtS: 40
GCID: GC14P067656
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family with sequence similarity 71, member D(Previous name: chromosome 14 open reading frame 54 )
(Previous symbol: C14orf54)
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Aliases
for FAM71D gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 71, Member D1 2 | | C14orf541 2 3 | | Chromosome 14 Open Reading Frame 541 | | Protein FAM71D2 |
Export aliases for FAM71D gene to outside databasesPrevious GC identifers: GC14P066726 GC14P047825 |
Summaries
for FAM71D gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM71D gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM71D gene promoter:
Oct-B1 oct-B2 HTF Evi-1 FAC1 POU2F1 POU2F1a POU2F1b POU2F1c TGIF
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM71D
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM71D |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q23.3 Ensembl cytogenetic band: 14q23.3 HGNC cytogenetic band: 14q23.3FAM71D Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14P067656: view genomic region
(about GC identifiers)
Start:
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67,656,110 bp from pter |
End:
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67,695,267 bp from pter |
Size:
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39,158 bases |
Orientation:
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plus strand |
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Proteins
for FAM71D gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FA71D_HUMAN, Q8N9W8 (See
protein sequence)Recommended Name: Protein FAM71D Size: 422 amino acids; 47076 Da
Secondary accessions: Q86VN4Alternative splicing: 2 isoforms: Q8N9W8-1 Q8N9W8-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM71D: NX_Q8N9W8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N9W8
FAM71D Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_775797.2
ENSEMBL proteins: ENSP00000436280 ENSP00000431905 ENSP00000433183 ENSP00000454526 ENSP00000432195 ENSP00000451865 ENSP00000451960 ENSP00000450695
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
FAM71D for ontologies About GeneDecksing
FAM71D Antibody Products:
Assay Products for FAM71D: |
Protein
Domains /
Families
for FAM71D gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM71D for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8N9W8ProtoNet protein and cluster: Q8N9W8 UniProtKB/Swiss-Prot: FA71D_HUMAN, Q8N9W8Similarity: Belongs to the FAM71 family |
Function
for FAM71D gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM71D (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM71D (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM71D (NM_173526) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM71D | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM71D |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM71D |
|
Pathways & Interactions
for FAM71D gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM71D
|
Drugs & Compounds
for FAM71D gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM71D
Search CenterWatch for drugs/clinical trials and news about FAM71D / FA71D
|
Transcripts
for FAM71D gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM71D gene: NM_173526.3 Unigene Cluster for FAM71D: Family with sequence similarity 71, member D Hs.412818 [show with all ESTs]Unigene Representative Sequence: NM_17352611 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000524532 ENST00000311864(uc001xja.2 uc010aqn.2) ENST00000530728
ENST00000524914(uc010tsv.2 uc001xiz.3) ENST00000534174 ENST00000556046
ENST00000553590 ENST00000531566 ENST00000556117 ENST00000557671 ENST00000554500
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM71D (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM71D (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM71D (NM_173526) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM71D | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM71D |
Additional cDNA sequence: AK093449.1 AK302154.1 BC037380.1 BC050401.1 7 DOTS entries: DT.75199969 DT.100039443 DT.100743925 DT.100674146 DT.416381 DT.100680917 DT.120773233 20 AceView cDNA sequences: AK093449 BI832052 AI191975 BC050401 BC037380 NM_173526 AA718918 AX748134 BI831380 AA399527 BU101741 BI826576 AA398093 AI699453 AI956014 CD244027 BM908047 AI925089 BF881294 AA831479
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for FAM71D About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 |
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| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM71D
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Expression
for FAM71D gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM71D expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for FAM71D
SOURCE GeneReport for Unigene cluster: Hs.412818
SABiosciences Custom PCR Arrays for FAM71D
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM71D
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM71D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM71D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM71D | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM71D |
Orthologs
for FAM71D gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM71D gene from 2/8 species (see all 8) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
FAM71D6 |
Uncharacterized protein |
33(a) |
1 ↔ 1 |
5(31338288-31340838) |
lizard
(Anolis carolinensis) |
Reptilia |
FAM71D6 |
-- |
45(a) |
1 ↔ 1 |
GL343272.1(1359617-1367456) |
ENSEMBL Gene Tree for FAM71D (if available)
TreeFam Gene Tree for FAM71D (if available) |
Paralogs
for FAM71D gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM71D gene
- FAM71E12 FAM71A2 ENSG000002677062 FAM71E22 FAM71B2 FAM71C2 FAM71F22 FAM71F12
1 SIMAP similar gene for FAM71D using alignment to 7 protein entries: FA71D_HUMAN (see all proteins):FAM71C
FAM71D for paralogs About GeneDecksing
|
Genomic Variants
for FAM71D gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM71D (67656110 - 67695267 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FAM71D
1 CNV: 8772 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for FAM71D gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM71D gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM71D gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM71D) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM71D gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM71D gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM71D gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM71D gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM71D | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM71D gene:
Search GeneIP for patents involving FAM71D
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM71D gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM71D | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM71D | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM71D | | | OriGene Protein Over-expression Lysate for FAM71D | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM71D | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM71D | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM71D | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM71D | | OriGene Custom Protein Services for FAM71D | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM71D | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM71D | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM71D | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM71D | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM71D | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM71D |
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 |  |  |  | |
| | | | Search Tocris compounds for FAM71D |
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 | | | FAM71D Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM71D |
|  |  |  | | | | ThermoFisher Antibody for FAM71D |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM71D |
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