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Aliases for FAM71C Gene

Aliases for FAM71C Gene

  • Family With Sequence Similarity 71 Member C 2 3 5
  • Family With Sequence Similarity 71, Member C 2

External Ids for FAM71C Gene

Previous GeneCards Identifiers for FAM71C Gene

  • GC12P098544
  • GC12P100041
  • GC12P097103

Summaries for FAM71C Gene

GeneCards Summary for FAM71C Gene

FAM71C (Family With Sequence Similarity 71 Member C) is a Protein Coding gene. An important paralog of this gene is FAM71F1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM71C Gene

Genomics for FAM71C Gene

Regulatory Elements for FAM71C Gene


Genomic Location for FAM71C Gene

Chromosome:
12
Start:
99,647,750 bp from pter
End:
99,650,114 bp from pter
Size:
2,365 bases
Orientation:
Plus strand

Genomic View for FAM71C Gene

Genes around FAM71C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM71C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM71C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM71C Gene

Proteins for FAM71C Gene

  • Protein details for FAM71C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NEG0-FA71C_HUMAN
    Recommended name:
    Protein FAM71C
    Protein Accession:
    Q8NEG0
    Secondary Accessions:
    • B2R6Y6

    Protein attributes for FAM71C Gene

    Size:
    241 amino acids
    Molecular mass:
    27472 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM71C Gene

Proteomics data for FAM71C Gene at MOPED

Post-translational modifications for FAM71C Gene

No Post-translational modifications

Other Protein References for FAM71C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM71C Gene

Domains & Families for FAM71C Gene

Protein Domains for FAM71C Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM71C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NEG0

UniProtKB/Swiss-Prot:

FA71C_HUMAN :
  • Belongs to the FAM71 family.
Family:
  • Belongs to the FAM71 family.
genes like me logo Genes that share domains with FAM71C: view

No data available for Gene Families for FAM71C Gene

Function for FAM71C Gene

genes like me logo Genes that share phenotypes with FAM71C: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM71C Gene

Localization for FAM71C Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM71C Gene COMPARTMENTS Subcellular localization image for FAM71C gene
Compartment Confidence
nucleus 4
cytosol 2
cytoskeleton 1
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM71C Gene

Pathways & Interactions for FAM71C Gene

SuperPathways for FAM71C Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM71C Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM71C Gene

Drugs & Compounds for FAM71C Gene

No Compound Related Data Available

Transcripts for FAM71C Gene

mRNA/cDNA for FAM71C Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(11) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM71C Gene

Family with sequence similarity 71, member C:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM71C Gene

No ASD Table

Relevant External Links for FAM71C Gene

GeneLoc Exon Structure for
FAM71C
ECgene alternative splicing isoforms for
FAM71C

Expression for FAM71C Gene

mRNA expression in normal human tissues for FAM71C Gene

mRNA differential expression in normal tissues according to GTEx for FAM71C Gene

This gene is overexpressed in Testis (x51.6).

Protein differential expression in normal tissues from HIPED for FAM71C Gene

This gene is overexpressed in Monocytes (60.1) and Brain (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM71C Gene



SOURCE GeneReport for Unigene cluster for FAM71C Gene Hs.591011

genes like me logo Genes that share expression patterns with FAM71C: view

Protein tissue co-expression partners for FAM71C Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM71C Gene

Orthologs for FAM71C Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM71C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM71C 35
  • 98.76 (n)
  • 97.51 (a)
FAM71C 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM71C 36
  • 29 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 57 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 67 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 45 (a)
ManyToMany
-- 36
  • 38 (a)
ManyToMany
Species with no ortholog for FAM71C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM71C Gene

ENSEMBL:
Gene Tree for FAM71C (if available)
TreeFam:
Gene Tree for FAM71C (if available)

Paralogs for FAM71C Gene

(5) SIMAP similar genes for FAM71C Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for FAM71C Gene

genes like me logo Genes that share paralogs with FAM71C: view

Variants for FAM71C Gene

Sequence variations from dbSNP and Humsavar for FAM71C Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
VAR_029638 -
VAR_029639 -

Structural Variations from Database of Genomic Variants (DGV) for FAM71C Gene

Variant ID Type Subtype PubMed ID
esv32717 CNV Gain 17666407

Variation tolerance for FAM71C Gene

Residual Variation Intolerance Score: 84.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.24; 81.11% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM71C Gene

Human Gene Mutation Database (HGMD)
FAM71C

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM71C Gene

Disorders for FAM71C Gene

Relevant External Links for FAM71C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM71C

No disorders were found for FAM71C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM71C Gene

Publications for FAM71C Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for FAM71C Gene

Sources for FAM71C Gene

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