Aliases for FAM71C Gene
Aliases for FAM71C Gene
External Ids for FAM71C Gene
- HGNC: 28594
- Entrez Gene: 196472
- Ensembl: ENSG00000180219
- UniProtKB: Q8NEG0
Previous GeneCards Identifiers for FAM71C Gene
- GC12P098544
- GC12P100041
- GC12P097103
Summaries for FAM71C Gene
GeneCards Summary for FAM71C Gene
FAM71C (Family With Sequence Similarity 71 Member C) is a Protein Coding gene. An important paralog of this gene is FAM71A.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM71C Gene
Genomics for FAM71C Gene
Regulatory Elements for FAM71C Gene
Enhancers for FAM71C Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH12G099609 | 0.4 | ENCODE | 11.2 | -38.0 | -38011 | 0.3 | POU5F1 | FAM71C GC12P099593 GC12P099640 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around FAM71C on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM71C gene promoter:
Regulatory Element Products
Genomic Location for FAM71C Gene
- Chromosome:
- 12
- Start:
- 99,647,750 bp from pter
- End:
- 99,650,114 bp from pter
- Size:
- 2,365 bases
- Orientation:
- Plus strand
Genomic View for FAM71C Gene
Genes around FAM71C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q23.1 by Ensembl
- 12q23.1 by Entrez Gene
- 12q23.1 by HGNC
FAM71C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM71C Gene
Proteins for FAM71C Gene
-
Protein details for FAM71C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NEG0-FA71C_HUMAN
- Recommended name:
- Protein FAM71C
- Protein Accession:
- Q8NEG0
- B2R6Y6
Protein attributes for FAM71C Gene
- Size:
- 241 amino acids
- Molecular mass:
- 27472 Da
- Quaternary structure:
- No Data Available
Protein Expression for FAM71C Gene
Post-translational modifications for FAM71C Gene
No Post-translational modifications
Other Protein References for FAM71C Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Protein Products
-
OriGene Purified Proteins for FAM71C
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM71C
- Origene Custom Protein Services for FAM71C
- Novus Biologicals lysates for FAM71C
- Search GeneTex for Proteins for FAM71C
Assay Products
No data available for DME Specific Peptides for FAM71C Gene
Domains & Families for FAM71C Gene
Suggested Antigen Peptide Sequences for FAM71C Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8NEG0- Family:
-
- Belongs to the FAM71 family.
No data available for Gene Families for FAM71C Gene
Function for FAM71C Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for FAM71C Gene
- GenomeRNAi human phenotypes for FAM71C:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM71C gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71C gene
- Search ViGene Biosciences for FAM71C
CRISPR Products
-
OriGene CRISPR knockouts for FAM71C
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM71C
- GenScript: Design CRISPR guide RNA sequences for FAM71C
miRNA Products
- Search ViGene Biosciences for FAM71C
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for FAM71C
- Browse OriGene Inhibitory RNA Products For FAM71C
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71C gene
Clone Products
-
OriGene ORF clones in human for FAM71C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
Horizon Cell Lines for FAM71C
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM71C gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM71C gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71C gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM71C Gene
Localization for FAM71C Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM71C Gene
Pathways & Interactions for FAM71C Gene
No Data Available
Interacting Proteins for FAM71C Gene
Selected Interacting proteins:
Q8NEG0-FA71C_HUMAN
ENSP00000315247
for FAM71C Gene via
IID
UniProtKB
STRING
No data available for Pathways by source and SIGNOR curated interactions for FAM71C Gene
Transcripts for FAM71C Gene
mRNA/cDNA for FAM71C Gene
- (1) REFSEQ mRNAs :
- (2) Additional mRNA sequences :
- (11) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM71C Gene
CRISPR Products
-
OriGene CRISPR knockouts for FAM71C
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM71C
- GenScript: Design CRISPR guide RNA sequences for FAM71C
miRNA Products
- Search ViGene Biosciences for FAM71C
Inhibitory RNA Products
- Origene RNAi, shRNA, and siRNA products in human, mouse, rat for FAM71C
- Browse OriGene Inhibitory RNA Products For FAM71C
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM71C gene
Clone Products
-
OriGene ORF clones in human for FAM71C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for FAM71C Gene
mRNA differential expression in normal tissues according to GTEx for FAM71C Gene
This gene is overexpressed in Testis (x51.6).
This gene is overexpressed in Monocytes (60.1) and Brain (6.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM71C Gene
NURSA nuclear receptor signaling pathways regulating expression of FAM71C Gene:
FAM71CSOURCE GeneReport for Unigene cluster for FAM71C Gene:
Hs.591011Primer Products
-
OriGene qPCR primer pairs for FAM71C
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM71C Gene
Orthologs for FAM71C Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FAM71C 34 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | FAM71C 35 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany |
- Species where no ortholog for FAM71C was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- mouse (Mus musculus)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for FAM71C Gene
Paralogs for FAM71C Gene
(5) SIMAP similar genes for FAM71C Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for FAM71C Gene
Variants for FAM71C Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000161240 | -- | 99,647,144(+) | ATACA(C/T)GTGGT | intron-variant, upstream-variant-2KB | |
| rs1001030962 | -- | 99,647,208(+) | TATTC(C/T)TTAAG | intron-variant, upstream-variant-2KB | |
| rs1002042865 | -- | 99,646,227(+) | ACTTT(A/G)GGAAG | intron-variant, upstream-variant-2KB | |
| rs1002279155 | -- | 99,647,897(+) | GCCCG(C/G)ACATC | intron-variant, utr-variant-5-prime | |
| rs1002289104 | -- | 99,647,715(+) | ATGGG(G/T)AGGGG | intron-variant, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1549n100 | CNV | loss | 25217958 |
| dgv2824n54 | CNV | loss | 21841781 |
| esv32717 | CNV | gain | 17666407 |
| nsv1045504 | CNV | loss | 25217958 |
| nsv559954 | CNV | loss | 21841781 |
| nsv559956 | CNV | loss | 21841781 |
| nsv559958 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
84.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.24;
81.11% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM71C Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM71C Gene
Disorders for FAM71C Gene
Relevant External Links for FAM71C
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM71C
No disorders were found for FAM71C Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM71C Gene
Publications for FAM71C Gene
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
- Toward an understanding of the protein interaction network of the human liver. (PMID: 21988832) Wang J. … Yang X. (Mol. Syst. Biol. 2011) 3 64
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3 64
Products for FAM71C Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FAM71C
- Search Origene for MassSpec and Protein Over-expression Lysates for FAM71C
- Origene Custom Protein Services for FAM71C
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for FAM71C
- Browse OriGene Inhibitory RNA Products For FAM71C
- OriGene qPCR primer pairs for FAM71C
- OriGene CRISPR knockouts for FAM71C
- OriGene ORF clones in human for FAM71C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FAM71C
- GenScript: Next-day shipping cDNA ORF clone for FAM71C in any vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM71C
- GenScript Custom Assay Services for FAM71C
- GenScript Custom overexpressing Cell Line Services for FAM71C
- GenScript: Design CRISPR guide RNA sequences for FAM71C
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM71C
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals lysates for FAM71C
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ViGene Biosciences adenoviral particle packaged cDNA for FAM71C gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM71C gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM71C gene
- Search ViGene Biosciences for FAM71C
- Horizon Cell Lines for FAM71C
- Cyagen custom Knockout/knockin (KOKI) mouse models for FAM71C
- VectorBuilder custom plasmid, inducible vectors for FAM71C
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for FAM71C
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for FAM71C Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer