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Aliases for FAM71B Gene

Aliases for FAM71B Gene

  • Family With Sequence Similarity 71, Member B 2 3

External Ids for FAM71B Gene

Summaries for FAM71B Gene

GeneCards Summary for FAM71B Gene

FAM71B (Family With Sequence Similarity 71, Member B) is a Protein Coding gene. An important paralog of this gene is FAM71F1.

UniProtKB/Swiss-Prot for FAM71B Gene

  • May be involved in RNA biogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM71B Gene

Genomics for FAM71B Gene

Genomic Location for FAM71B Gene

Start:
157,161,846 bp from pter
End:
157,166,268 bp from pter
Size:
4,423 bases
Orientation:
Minus strand

Genomic View for FAM71B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM71B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM71B Gene

Regulatory Elements for FAM71B Gene

Proteins for FAM71B Gene

  • Protein details for FAM71B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TC56-FA71B_HUMAN
    Recommended name:
    Protein FAM71B
    Protein Accession:
    Q8TC56
    Secondary Accessions:
    • Q1EDD9
    • Q8TC64
    • Q96LY8

    Protein attributes for FAM71B Gene

    Size:
    605 amino acids
    Molecular mass:
    64756 Da
    Quaternary structure:
    • Interacts with FRG1.

neXtProt entry for FAM71B Gene

Proteomics data for FAM71B Gene at MOPED

Post-translational modifications for FAM71B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM71B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM71B Gene

Domains for FAM71B Gene

Protein Domains for FAM71B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM71B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8TC56

UniProtKB/Swiss-Prot:

FA71B_HUMAN
Family:
  • Belongs to the FAM71 family.:
    • Q8TC56
genes like me logo Genes that share domains with FAM71B: view

No data available for Gene Families for FAM71B Gene

Function for FAM71B Gene

Molecular function for FAM71B Gene

UniProtKB/Swiss-Prot Function: May be involved in RNA biogenesis.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM71B Gene

Localization for FAM71B Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM71B Gene

Nucleus. Note=Cajal body and speckle localization.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM71B Gene COMPARTMENTS Subcellular localization image for FAM71B gene
Compartment Confidence
nucleus 5
cytosol 3

Gene Ontology (GO) - Cellular Components for FAM71B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with FAM71B: view

Pathways for FAM71B Gene

SuperPathways for FAM71B Gene

No Data Available

Interacting Proteins for FAM71B Gene

Gene Ontology (GO) - Biological Process for FAM71B Gene

None

No data available for Pathways by source for FAM71B Gene

Transcripts for FAM71B Gene

mRNA/cDNA for FAM71B Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(183) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM71B Gene

Family with sequence similarity 71, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM71B Gene

No ASD Table

Relevant External Links for FAM71B Gene

GeneLoc Exon Structure for
FAM71B
ECgene alternative splicing isoforms for
FAM71B

Expression for FAM71B Gene

mRNA expression in normal human tissues for FAM71B Gene

mRNA differential expression in normal tissues according to GTEx for FAM71B Gene

This gene is overexpressed in Testis (52.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM71B Gene

SOURCE GeneReport for Unigene cluster for FAM71B Gene Hs.666099

genes like me logo Genes that share expressions with FAM71B: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM71B Gene

Orthologs for FAM71B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM71B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM71B 35
  • 98.51 (n)
  • 97.19 (a)
FAM71B 36
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM71B 35
  • 76.11 (n)
  • 66.72 (a)
FAM71B 36
  • 66 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM71B 35
  • 77.41 (n)
  • 67.45 (a)
FAM71B 36
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam71b 35
  • 70.7 (n)
  • 60.28 (a)
Fam71b 16
Fam71b 36
  • 52 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 67 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam71b 35
  • 71.12 (n)
  • 60.96 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 49 (a)
ManyToMany
-- 36
  • 45 (a)
ManyToMany
Species with no ortholog for FAM71B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM71B Gene

ENSEMBL:
Gene Tree for FAM71B (if available)
TreeFam:
Gene Tree for FAM71B (if available)

Paralogs for FAM71B Gene

Selected SIMAP similar genes for FAM71B Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for FAM71B Gene

genes like me logo Genes that share paralogs with FAM71B: view

Variants for FAM71B Gene

Sequence variations from dbSNP and Humsavar for FAM71B Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type MAF
rs31207 -- 157,162,177(-) TGTTC(A/G)GCTTT downstream-variant-500B
rs31208 - 157,162,574(+) CCACC(A/G)TCTTA missense, reference
rs31215 -- 157,168,159(-) ttaca(G/T)atgtg upstream-variant-2KB
rs31216 -- 157,166,962(-) AGGCA(A/G)GAGGA upstream-variant-2KB
rs31217 -- 157,166,950(-) CACTT(A/G)AACCT upstream-variant-2KB

Relevant External Links for FAM71B Gene

HapMap Linkage Disequilibrium report
FAM71B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM71B Gene

Disorders for FAM71B Gene

(1) University of Copenhagen DISEASES for FAM71B Gene

Relevant External Links for FAM71B

Genetic Association Database (GAD)
FAM71B
genes like me logo Genes that share disorders with FAM71B: view

No data available for UniProtKB/Swiss-Prot for FAM71B Gene

Publications for FAM71B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  4. Proteomic characterization of the human sperm nucleus. (PMID: 21630459) de Mateo S. … Oliva R. (Proteomics 2011) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM71B Gene

Sources for FAM71B Gene

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