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FAM65B Gene

protein-coding   GIFtS: 50
GCID: GC06M024804

Family With Sequence Similarity 65, Member B

(Previous name: chromosome 6 open reading frame 32)
(Previous symbol: C6orf32)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 65, Member B1 2     Myogenesis-Related And NCAM-Associated Protein Homolog (Chicken)1
C6orf321 2 3 5     DIFF402
PL482 3 5     MYONAP2
DIFF482 3     Myogenesis-Related And NCAM-Associated Protein Homolog2
KIAA03863 5     Protein FAM65B2
Chromosome 6 Open Reading Frame 321     

External Ids:    HGNC: 138721   Entrez Gene: 97502   Ensembl: ENSG000001119137   OMIM: 6114105   UniProtKB: Q9Y4F93   

Export aliases for FAM65B gene to outside databases

Previous GC identifer: GC06M024913


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FAM65B Gene:
The protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from
proliferative cytotrophoblasts during trophoblast differentiation. Alternative splicing of this gene results in
multiple transcript variants. (provided by RefSeq, Nov 2013)

GeneCards Summary for FAM65B Gene:
FAM65B (family with sequence similarity 65, member B) is a protein-coding gene. An important paralog of this gene is FAM65A.

UniProtKB/Swiss-Prot: FA65B_HUMAN, Q9Y4F9
Function: Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and
filopodia formation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM65B gene promoter:
         IRF-2   POU2F1   POU2F1a   STAT5A   NF-E2 p45   NF-E2   LCR-F1   Evi-1   FOXL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM65B promoter sequence
   Search Chromatin IP Primers for FAM65B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM65B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.3-p21.32   Ensembl cytogenetic band:  6p22.3   HGNC cytogenetic band: 6p22.3-p21.32

FAM65B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM65B gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M024804:  view genomic region     (about GC identifiers)

Start:
24,797,601 bp from pter      End:
25,042,238 bp from pter
Size:
244,638 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FA65B_HUMAN, Q9Y4F9 (See protein sequence)
Recommended Name: Protein FAM65B  
Size: 1068 amino acids; 118519 Da
Miscellaneous: Cells lacking isoform 2 exhibit a severe reduction of myotube formation. In contrast, isoform 2
overexpression induces formation of filopodia
Sequence caution: Sequence=AAC51134.1; Type=Frameshift; Positions=Several; Sequence=BAA20840.2; Type=Erroneous
initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NHP2 Q13529 Q5VV37 Q5VV38 Q9BQ28
Alternative splicing: 2 isoforms:  Q9Y4F9-1   Q9Y4F9-2   

Explore the universe of human proteins at neXtProt for FAM65B: NX_Q9Y4F9

Explore proteomics data for FAM65B at MOPED

Post-translational modifications: 

  • Asn-41 was reported (PubMed:16335952) to be N-glycosylated; however as this position is probably not
    extracellular, the in vivo relevance is not proven1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM65B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001273374.1  NP_001273375.1  NP_001273376.1  NP_055537.2  NP_056948.2  

    ENSEMBL proteins: 
     ENSP00000455145   ENSP00000259698   ENSP00000367262   ENSP00000441138   ENSP00000441305  
     ENSP00000438425  

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    Cloud-Clone Corp. Proteins for FAM65B

     
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    antibodies-online proteins for FAM65B (3 products) 

     
    antibodies-online peptides for FAM65B

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    antibodies-online antibodies for FAM65B (25 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR016024 ARM-type_fold
     IPR026136 FAM65

    Graphical View of Domain Structure for InterPro Entry Q9Y4F9

    ProtoNet protein and cluster: Q9Y4F9

    UniProtKB/Swiss-Prot: FA65B_HUMAN, Q9Y4F9
    Similarity: Belongs to the FAM65 family


    Find genes that share domains with FAM65B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FA65B_HUMAN, Q9Y4F9
    Function: Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and
    filopodia formation

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
         
    Find genes that share ontologies with FAM65B           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for FAM65B:
     Increased G1 DNA content  Increased cell number in G2M,  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM65B
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    miRNA
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    miRTarBase miRNAs that target FAM65B:
    hsa-mir-124-3p (MIRT022201)

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    Selected qRT-PCR Assays for microRNAs that regulate FAM65B (see all 59):
    hsa-miR-513a-5p hsa-miR-15a hsa-miR-146a hsa-miR-548k hsa-miR-128 hsa-miR-503 hsa-miR-29a hsa-miR-628-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM65B 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FA65B_HUMAN, Q9Y4F9: Isoform 1: Mitochondrion
    FA65B_HUMAN, Q9Y4F9: Isoform 2: Cytoplasm, cytoskeleton. Cell projection, filopodium. Note=Detected in cellular
    filopodia
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    mitochondrion5
    cytosol2
    nucleus2
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--
    GO:0005856cytoskeleton IEA--
    GO:0030175filopodium IEA--

    Find genes that share ontologies with FAM65B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM65B
    Interactions:

        Search GeneGlobe Interaction Network for FAM65B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for FAM65B (Q9Y4F93 ENSP000002596984) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    YWHAGP619813, ENSP000003063304I2D: score=3 STRING: ENSP00000306330
    YWHAZP631043, ENSP000003095034I2D: score=2 STRING: ENSP00000309503
    WNK1Q9H4A33, ENSP000003130594I2D: score=1 STRING: ENSP00000313059
    RPS6KA3P518123I2D: score=2 
    YWHAEP622583I2D: score=2 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007517muscle organ development IEA--
    GO:0030154cell differentiation IEA--

    Find genes that share ontologies with FAM65B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM65B (FA65B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM65B gene (5 alternative transcripts): 
    NM_001286445.1  NM_001286446.1  NM_001286447.1  NM_014722.3  NM_015864.3  

    Unigene Cluster for FAM65B:

    Family with sequence similarity 65, member B
    Hs.559459  [show with all ESTs]
    Unigene Representative Sequence: NM_014722
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000562221 ENST00000259698(uc003neo.1 uc011djs.1) ENST00000463828
    ENST00000378023(uc003nep.3) ENST00000473070 ENST00000538035 ENST00000510784
    ENST00000540914(uc011djt.2 uc011dju.2)
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate FAM65B (see all 59):
    hsa-miR-513a-5p hsa-miR-15a hsa-miR-146a hsa-miR-548k hsa-miR-128 hsa-miR-503 hsa-miR-29a hsa-miR-628-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM65B 3' UTR sequence
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      QuantiFast Probe-based Assays in human, mouse, rat FAM65B

    Additional mRNA sequence: 

    AB002384.1 AF085914.1 AK096033.1 AK299047.1 AK300138.1 AK300950.1 BC000930.2 BC001232.1 
    U49187.1 

    17 DOTS entries:

    DT.95170505  DT.86854476  DT.409096  DT.91967050  DT.95170507  DT.100705443  DT.40120076  DT.95170508 
    DT.95170511  DT.99933741  DT.100744724  DT.121365611  DT.121365654  DT.121365666  DT.95170506  DT.95170510 
    DT.91993529 

    Selected AceView cDNA sequences (see all 160):

    AI222026 AA768221 AI741933 BP381591 AA808034 BX492900 AW572692 AA280918 
    BM721746 AI219533 BM919248 AA832442 AI440344 AW950867 BX324874 NM_015864 
    AI434379 AI809847 BM463096 BC000930 BI908375 BM917716 BC001232 BQ710013 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for FAM65B    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19a · 19b ^ 20 ^ 21a · 21b ^ 22 ^
    SP1:                                                                                            -     -           -           -                                 
    SP2:                                                                                -           -                                                               
    SP3:                                                                                -                                                                           
    SP4:                                                                                                                          -                                 
    SP5:                                                                                                                                                            

    ExUns: 23 ^ 24 ^ 25
    SP1:                  
    SP2:                  
    SP3:                  
    SP4:                  
    SP5:                  


    ECgene alternative splicing isoforms for FAM65B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM65B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAGTTAAAA
    FAM65B Expression
    About this image


    FAM65B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Cerebral Cortex
     
     Thymus (Hematopoietic System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             T Helper Cells Thymus
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
    FAM65B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM65B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.559459

    UniProtKB/Swiss-Prot: FA65B_HUMAN, Q9Y4F9
    Tissue specificity: Isoform 1 is present in the brain. Isoform 2 is expressed during differentiation of fetal
    primary myoblasts. Also shows marked expression during cytotrophoblast differentiation

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM65B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM65B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam65b1 , 5 family with sequence similarity 65, member B1, 5 84.92(n)1
    89.14(a)1
      13 (10.50 cM)5
    1933851  NM_029679.21  NP_083955.11 
     245821895 
    chicken
    (Gallus gallus)
    Aves FAM65B1 family with sequence similarity 65, member B 74.33(n)
    78.39(a)
      421003  NM_001012865.1  NP_001012883.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM65B6
    family with sequence similarity 65, member B
    71(a)
    1 ↔ 1
    4(53834745-53906466)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fam65b1 family with sequence similarity 65, member B 67.61(n)
    66.45(a)
      100170496  NM_001130276.1  NP_001123748.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam65b1 family with sequence similarity 65, member B 59.96(n)
    57.16(a)
      563800  NM_001045026.1  NP_001038491.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C27H2.26
    Protein C27H2.2, isoform a (C27H2.2) mRNA, complet...
    20(a)
    1 → many
    IV(13952715-13964001) WBGene00007782


    ENSEMBL Gene Tree for FAM65B (if available)
    TreeFam Gene Tree for FAM65B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM65B gene
    FAM65A2  FAM65C2  
    2 SIMAP similar genes for FAM65B using alignment to 5 protein entries:     FA65B_HUMAN (see all proteins):
    FAM65A    FAM65C

    Find genes that share paralogs with FAM65B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM65B (see all 2156)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1903207851,2
    --24804161(+) GCACTC/TTGGGA 1 -- ds50010--------
    rs1810096261,2
    --24804229(+) AGAAAA/CCCCAT 1 -- ds50010--------
    rs44906551,2
    C,F,A--24804299(+) TCGAGA/GGGCTG 1 -- ds50014Minor allele frequency- G:0.38NA WA CSA 8
    rs1420344811,2
    C--24804327(+) GAACTC/TGGGAG 1 -- ds50010--------
    rs44875681,2
    C,F,A--24804363(+) GCACCG/ATTGCA 1 -- ds50014Minor allele frequency- A:0.38NA WA CSA 8
    rs122136821,2
    C,F--24804377(+) CAGCCA/GGGGCA 1 -- ds50014Minor allele frequency- G:0.25NA WA 8
    rs1860360511,2
    --24804517(+) TGCTAA/GTAATT 1 -- ut310--------
    rs1897095511,2
    --24804523(+) TAATTA/CAAAAA 1 -- ut310--------
    rs1813012441,2
    --24804551(+) TACATA/GACTGA 1 -- ut310--------
    rs716557891,2
    C--24804593(+) AAGCA-/CCCCCT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for FAM65B (24797601 - 25042238 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FAM65B (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv435839CNV Deletion17901297
    esv2667409CNV Deletion23128226
    esv2592028CNV Deletion19546169
    esv998494CNV Deletion20482838
    esv2556930CNV Deletion19546169
    esv2731716CNV Deletion23290073
    esv2171182CNV Deletion18987734
    esv1071217CNV Deletion17803354
    esv2731717CNV Deletion23290073
    esv5139CNV Deletion18987735

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611410    OMIM disorders: --


    Find genes that share disorders with FAM65B           About GenesLikeMe

    Genetic Association Database (GAD): FAM65B
    Human Genome Epidemiology (HuGE) Navigator: FAM65B (1 document)

    Export disorders for FAM65B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM65B gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with FAM65B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. C6ORF32 is upregulated during muscle cell differentiation and induces the formation of cellular filopodia. (PubMed id 17150207)1, 2, 3 Yoon S.... Gussoni E. (Dev. Biol. 2007)
    2. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1997)
    3. Identification and characterization of a novel neural cell adhesion molecule (NCAM)-associated protein from quail myoblasts: relationship to myotube formation and induction of neurite-like protrusions. (PubMed id 17825087)1, 3 Hirayama E. and Kim J. ( research in biological diversity 2008)
    4. PL48: a novel gene associated with cytotrophoblast and lineage- specific HL-60 cell differentiation. (PubMed id 9055809)1, 2 Dakour J.... Morrish D.W. (Gene 1997)
    5. Family-based genome-wide association study of frontal I, oscillations identifies potassium channel gene KCNJ6. (PubMed id 22554406)1 Kang S.J....Porjesz B. (Genes Brain Behav. 2012)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. A human MAP kinase interactome. (PubMed id 20936779)1 Bandyopadhyay S....Ideker T. (Nat. Methods 2010)
    8. PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis. (PubMed id 21190562)1 Zhang K. and Waxman D.J. (Mol. Cancer 2010)
    9. Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment. (PubMed id 19367720)2 Carrascal M.... Abian J. (J. Proteome Res. 2008)
    10. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9750 HGNC: 13872 AceView: C6orf32 Ensembl:ENSG00000111913 euGenes: HUgn9750
    ECgene: FAM65B H-InvDB: FAM65B

    (According to HUGE)
    About This Section

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    HUGE: KIAA0386

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FAM65B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FAM65B gene:
    Search GeneIP for patents involving FAM65B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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