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FAM65A Gene

protein-coding   GIFtS: 49
GCID: GC16P067562

Family With Sequence Similarity 65, Member A

  Search for FAM65A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 65, Member A1 2
Protein FAM65A2
KIAA19303

External Ids:    HGNC: 258361   Entrez Gene: 795672   Ensembl: ENSG000000395237   UniProtKB: Q6ZS173   

Export aliases for FAM65A gene to outside databases

Previous GC identifers: GC16P066121 GC16P053436


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM65A Gene:
FAM65A (family with sequence similarity 65, member A) is a protein-coding gene. An important paralog of this gene is FAM65B.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NT_010498.16  NC_018927.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM65A gene promoter:
         STAT1   AML1a   HSF1 (long)   STAT1beta   STAT1alpha   MZF-1   c-Rel   HSF1short   STAT3   AP-2alpha isoform 4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM65A promoter sequence
   Search Chromatin IP Primers for FAM65A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM65A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

FAM65A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM65A gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P067562:  view genomic region     (about GC identifiers)

Start:
67,552,321 bp from pter      End:
67,580,691 bp from pter
Size:
28,371 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FA65A_HUMAN, Q6ZS17 (See protein sequence)
Recommended Name: Protein FAM65A  
Size: 1223 amino acids; 132308 Da
Sequence caution: Sequence=BAB14678.1; Type=Erroneous termination; Positions=256; Note=Translated as Glu;
Sequence=BAB67823.1; Type=Frameshift; Positions=579;
Secondary accessions: B4DEQ9 B4DIM2 E9PBS3 Q4G0A4 Q7Z5R7 Q8NDA4 Q96J39 Q96PV8 Q9H8D9
Alternative splicing: 4 isoforms:  Q6ZS17-1   Q6ZS17-2   Q6ZS17-3   Q6ZS17-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM65A: NX_Q6ZS17

Explore proteomics data for FAM65A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys916
  • Modification sites at PhosphoSitePlus

  • See FAM65A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001180451.1  NP_001180452.1  NP_001180453.1  NP_078795.2  

    ENSEMBL proteins: 
     ENSP00000455239   ENSP00000457739   ENSP00000368614   ENSP00000042381   ENSP00000443568  
     ENSP00000457888   ENSP00000456525   ENSP00000455795   ENSP00000389456   ENSP00000454376  
     ENSP00000456893   ENSP00000457419   ENSP00000455200   ENSP00000456924   ENSP00000400099  

    FAM65A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for FAM65A
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
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    Cloud-Clone Corp. Proteins for FAM65A

    FAM65A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals FAM65A Antibodies
    Abcam antibodies for FAM65A
    Cloud-Clone Corp. Antibodies for FAM65A
    Search ThermoFisher Antibodies for FAM65A
    LSBio Antibodies in human, mouse, rat for FAM65A

    FAM65A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FAM65A
    Cloud-Clone Corp. CLIAs for FAM65A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR016024 ARM-type_fold
     IPR026136 FAM65

    Graphical View of Domain Structure for InterPro Entry Q6ZS17

    ProtoNet protein and cluster: Q6ZS17

    1 Blocks protein domain: IPB011072 Protein kinase PKN/PRK1

    UniProtKB/Swiss-Prot: FA65A_HUMAN, Q6ZS17
    Similarity: Belongs to the FAM65 family


    FAM65A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005488binding ----
         
    FAM65A for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for FAM65A:
     G0/1 arrest  Increased G1 DNA content  Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM65A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM65A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM65A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM65A

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM65A:
    hsa-mir-342-5p (MIRT038228), hsa-mir-142-3p (MIRT021594)

    Block miRNA regulation of human, mouse, rat FAM65A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM65A (see all 9):
    hsa-miR-3163 hsa-miR-3607-3p hsa-miR-3194-5p hsa-miR-3664-5p hsa-miR-548aa hsa-miR-650 hsa-miR-1233 hsa-miR-656
    SwitchGear 3'UTR luciferase reporter plasmidFAM65A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM65A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM65A

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for FAM65A

    Clone
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    OriGene clones in human, mouse for FAM65A (see all 14)
    OriGene ORF clones in mouse, rat for FAM65A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): FAM65A (NM_024519)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM65A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM65A

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for FAM65A
    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM65A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM65A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FA65A_HUMAN, Q6ZS17: Cytoplasm (By similarity). Note=Localizes to the podocyte major processes and cell body (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    mitochondrion2
    nucleus2
    golgi apparatus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0070062extracellular vesicular exosome IDA19056867

    FAM65A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including FAM65A: 
              Polycomb & Trithorax Target Genes in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for FAM65A

    2 Interacting proteins for FAM65A (Q6ZS172, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP1LC3BQ9GZQ82, 3MINT-8259607 I2D: score=2 
    --Q9WMX22MINT-7049335
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction ----
    GO:0008150biological_process ND--

    FAM65A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM65A (FA65A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FAM65A gene (4 alternative transcripts): 
    NM_001193522.1  NM_001193523.1  NM_001193524.1  NM_024519.3  

    Unigene Cluster for FAM65A:

    Family with sequence similarity 65, member A
    Hs.152717  [show with all ESTs]
    Unigene Representative Sequence: NM_001193523
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000562116 ENST00000562755 ENST00000379312(uc010cei.2 uc002eth.3 uc010cej.3)
    ENST00000566522 ENST00000042381(uc010vjp.2 uc010vjq.2 uc002etk.3)
    ENST00000540839(uc002eti.2 uc002etj.1) ENST00000566907 ENST00000566920
    ENST00000565176 ENST00000428437 ENST00000569253 ENST00000566559 ENST00000566815
    ENST00000561534 ENST00000569474 ENST00000566730 ENST00000569179 ENST00000569733

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM65A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM65A (see all 9):
    hsa-miR-3163 hsa-miR-3607-3p hsa-miR-3194-5p hsa-miR-3664-5p hsa-miR-548aa hsa-miR-650 hsa-miR-1233 hsa-miR-656
    SwitchGear 3'UTR luciferase reporter plasmidFAM65A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM65A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM65A
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM65A (see all 14)
    OriGene ORF clones in mouse, rat for FAM65A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): FAM65A (NM_024519)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM65A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM65A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM65A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM65A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM65A
      QuantiFast Probe-based Assays in human, mouse, rat FAM65A

    Additional mRNA sequence: 

    AB067517.1 AK023787.1 AK127792.1 AK293748.1 AK295677.1 AL834312.1 BC001850.4 BC054512.1 
    BC098587.1 

    20 DOTS entries:

    DT.316621  DT.100778761  DT.120660138  DT.100662469  DT.91644585  DT.97859518  DT.95178730  DT.95307715 
    DT.97793077  DT.100742308  DT.120660082  DT.120660107  DT.91751899  DT.100778754  DT.121077904  DT.445039 
    DT.91680554  DT.91824969  DT.92420350  DT.95322472 

    Selected AceView cDNA sequences (see all 287):

    BU630066 AB067517 BE164151 BF063238 AA281365 BM715052 BF924664 BG110850 
    AI278692 BQ434531 BQ716819 BU739960 BQ068714 BM760678 AA341566 AW453014 
    CF272320 CK429706 BM985342 BQ083120 BU507635 BQ962009 BF434333 AI077937 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM65A (see all 15)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c ^ 16a · 16b ^
    SP1:                    -     -     -                                               -                                               -                           
    SP2:                                                  -                             -                                               -                           
    SP3:                                                  -     -     -                 -                                               -                           
    SP4:                    -     -     -     -     -     -     -     -                 -                                               -                           
    SP5:                    -     -     -                 -                             -                                                                           

    ExUns: 17a · 17b · 17c · 17d ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21 ^ 22a · 22b ^ 23 ^ 24a · 24b ^ 25 ^ 26 ^ 27a · 27b
    SP1:                                                                                                                  
    SP2:                                                                                                                  
    SP3:                                                                                                                  
    SP4:                                                                                                                  
    SP5:                                                                                                                  


    ECgene alternative splicing isoforms for FAM65A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM65A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTTCCTGGT
    FAM65A Expression
    About this image


    FAM65A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Thymus (Hematopoietic System)
             Thymus
     
     Inner Cell Mass (Early Embryonic Tissues)
             Blimp1- mVenus and stella-ECFP genetically modified stem cells
     
     Spleen (Hematopoietic System)
    FAM65A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM65A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.152717
        Pathway & Disease-focused RT2 Profiler PCR Array including FAM65A: 
              Polycomb & Trithorax Target Genes in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM65A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM65A
    QuantiTect SYBR Green Assays in human, mouse, rat FAM65A
    QuantiFast Probe-based Assays in human, mouse, rat FAM65A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM65A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM65A gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam65a1 , 5 family with sequence similarity 65, member A1, 5 82.77(n)1
    82.24(a)1
      8 (53.04 cM)5
    756871  NM_001081241.21  NP_001074710.21 
     1056052295 
    chicken
    (Gallus gallus)
    Aves FAM65A1 family with sequence similarity 65, member A 70.68(n)
    69.09(a)
      415665  XM_414032.4  XP_414032.4 
    lizard
    (Anolis carolinensis)
    Reptilia FAM65A6
    family with sequence similarity 65, member A
    49(a)
    1 ↔ 1
    GL343295.1(996863-1099067)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.208822 Xenopus laevis transcribed sequence with moderate similarity more 83.33(n)    BQ897438.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam65a1 family with sequence similarity 65, member A 63.99(n)
    63.65(a)
      566573  NM_001045108.2  NP_001038573.1 
    worm
    (Caenorhabditis elegans)
    Secernentea C27H2.26
    Protein C27H2.2, isoform a (C27H2.2) mRNA, complet...
    19(a)
    1 → many
    IV(13952715-13964001) WBGene00007782


    ENSEMBL Gene Tree for FAM65A (if available)
    TreeFam Gene Tree for FAM65A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM65A gene
    FAM65B2  FAM65C2  
    1 SIMAP similar gene for FAM65A using alignment to 10 protein entries:     FA65A_HUMAN (see all proteins):
    FAM65B

    FAM65A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM65A (see all 417)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1177794051,2
    C,F--67564860(+) CCCGCC/TCATCT 3 -- int11Minor allele frequency- T:0.01NA 120
    rs1512957911,2
    --67564884(+) CTCAGA/GTGGAC 3 -- int10--------
    rs1868006831,2
    --67565496(+) GGAGCA/GATGGG 3 -- int10--------
    rs1500014931,2
    C--67565563(+) TGGAAC/GAGAGA 3 -- int10--------
    rs1476676501,2
    --67565601(+) GTTGAA/GAGAAT 3 -- int10--------
    rs1423226901,2
    --67565639(+) CCTACC/GTGGGT 3 -- int10--------
    rs1463541721,2
    --67565669(+) TTTCTC/TCCTGG 3 -- int10--------
    rs1906026991,2
    --67565685(+) GAGTGG/TCTGTG 3 -- int10--------
    rs794722331,2
    --67565689(+) GGCTGG/TGGCTA 3 -- int10--------
    rs1389804521,2
    --67565829(+) TCGCTC/GTGTCG 3 -- int10--------

    HapMap Linkage Disequilibrium report for FAM65A (67552321 - 67580691 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for FAM65A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv270767CNV Insertion20981092
    esv29734CNV Loss19812545
    nsv906807CNV Loss21882294
    nsv524363CNV Loss19592680
    nsv833266CNV Loss17160897
    nsv827711CNV Gain20364138
    nsv522852CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM65A gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with FAM65A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    4. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    9. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79567 HGNC: 25836 AceView: FLJ13725 Ensembl:ENSG00000039523 euGenes: HUgn79567
    ECgene: FAM65A H-InvDB: FAM65A

    (According to HUGE)
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    HUGE: KIAA1930

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM65A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM65A gene:
    Search GeneIP for patents involving FAM65A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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