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FAM64A Gene

protein-coding   GIFtS: 44
GCID: GC17P006347

Family With Sequence Similarity 64, Member A

  Search for FAM64A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 64, Member A1 2     RCS12 3
CALM Interacting Protein Expressed In Thymus And Spleen1 2     CALM-Interactor Expressed In Thymus And Spleen2 3
Regulator Of Chromosome Segregation Protein 12 3     Protein FAM64A2
CATS2 3     Regulator Of Chromosome Segregation 12

External Ids:    HGNC: 254831   Entrez Gene: 544782   Ensembl: ENSG000001291957   UniProtKB: Q9BSJ63   

Export aliases for FAM64A gene to outside databases

Previous GC identifer: GC17P006289


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM64A Gene:
FAM64A (family with sequence similarity 64, member A) is a protein-coding gene.

UniProtKB/Swiss-Prot: FA64A_HUMAN, Q9BSJ6
Function: During mitosis, may play a role in the control of metaphase-to-anaphase transition




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NT_010718.17  NC_018928.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM64A gene promoter:
         RORalpha1   GR   p53   GR-beta   IRF-7A   GR-alpha   TGIF   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM64A promoter sequence
   Search Chromatin IP Primers for FAM64A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM64A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.2   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13.2

FAM64A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM64A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P006347:  view genomic region     (about GC identifiers)

Start:
6,347,735 bp from pter      End:
6,354,789 bp from pter
Size:
7,055 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FA64A_HUMAN, Q9BSJ6 (See protein sequence)
Recommended Name: Protein FAM64A  
Size: 248 amino acids; 27480 Da
Subunit: Isoform 1 and isoform 2 interact with PICALM; this interaction may target PICALM to the nucleus. During
mitosis, associates with HDAC2 and MTA2 subunits of the chromatin-remodeling NuRD complex; this association is
strongest at prometaphase and decreases as the cell progresses through metaphase and anaphase
Developmental stage: Regulated in a cell-cycle dependent manner, with lowest levels in quiescent cells or at G1
phase. Progressive up-regulation starting at S phase and peaking at G2 and G2/M phases, followed by a drastic
drop as cells exit mitosis (at protein level)
Secondary accessions: Q96CT4 Q9NVV1 Q9NWB5
Alternative splicing: 2 isoforms:  Q9BSJ6-1   Q9BSJ6-2   

Explore the universe of human proteins at neXtProt for FAM64A: NX_Q9BSJ6

Explore proteomics data for FAM64A at MOPED

Post-translational modifications: 

  • Ubiquitinated by the anaphase-promoting complex/cyclosome (APC/C) complex in the presence of FZR1, leading to its
    degradation by the proteasome during mitotic exit. However, degradation is not essential for normal mitotic
    progression within a single cell cycle1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM64A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001182157.1  NP_061886.2  

    ENSEMBL proteins: 
     ENSP00000459235   ENSP00000250056   ENSP00000460912   ENSP00000459597   ENSP00000460894  
     ENSP00000458584   ENSP00000458534   ENSP00000459860  

    FAM64A Human Recombinant Protein Products:

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    Cloud-Clone Corp. ELISAs for FAM64A
    Cloud-Clone Corp. CLIAs for FAM64A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009932 DUF1466

    Graphical View of Domain Structure for InterPro Entry Q9BSJ6

    ProtoNet protein and cluster: Q9BSJ6

    UniProtKB/Swiss-Prot: FA64A_HUMAN, Q9BSJ6
    Domain: The N-terminal destruction box 2 (D-box 2) is required for APC/C ubiquitination and proteasomal
    degradation (PubMed:18757745)


    FAM64A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FA64A_HUMAN, Q9BSJ6
    Function: During mitosis, may play a role in the control of metaphase-to-anaphase transition

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI16491119
         
    FAM64A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for FAM64A:
     Increased S DNA content  Increased cell size 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM64A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM64A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM64A

    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate FAM64A:
    hsa-miR-374b* hsa-miR-576-5p hsa-miR-520d-5p hsa-miR-3662 hsa-miR-524-5p hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidFAM64A 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for FAM64A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM64A

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    GenScript: all cDNA clones in your preferred vector (see all 2): FAM64A (NM_019013)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM64A

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM64A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FA64A_HUMAN, Q9BSJ6: Nucleus. Nucleus, nucleolus. Note=Partially localizes to the nucleolus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--

    FAM64A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM64A
    Interactions:

        Search GeneGlobe Interaction Network for FAM64A

    1 Interacting protein for FAM64A (Q9BSJ61, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRNPP041561, 3EBI-2568609,EBI-977302 I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--

    FAM64A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM64A (FA64A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FAM64A gene (2 alternative transcripts): 
    NM_001195228.1  NM_019013.2  

    Unigene Cluster for FAM64A:

    Family with sequence similarity 64, member A
    Hs.592116  [show with all ESTs]
    Unigene Representative Sequence: NM_019013
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000572447(uc002gcu.2 uc002gcw.2) ENST00000250056 ENST00000573557
    ENST00000571373 ENST00000570337 ENST00000572595 ENST00000576056 ENST00000573385
    ENST00000571572
    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate FAM64A:
    hsa-miR-374b* hsa-miR-576-5p hsa-miR-520d-5p hsa-miR-3662 hsa-miR-524-5p hsa-miR-32*
    SwitchGear 3'UTR luciferase reporter plasmidFAM64A 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM64A
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM64A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM64A
      QuantiFast Probe-based Assays in human, mouse, rat FAM64A

    Additional mRNA sequence: 

    AK001018.1 AK001353.1 AK225613.1 AK225702.1 BC005004.1 BC013966.2 

    13 DOTS entries:

    DT.100794432  DT.100794435  DT.208970  DT.100794433  DT.120948164  DT.120948165  DT.70103222  DT.97785567 
    DT.100794431  DT.102832102  DT.91752655  DT.97844613  DT.100672225 

    Selected AceView cDNA sequences (see all 171):

    CR617626 BQ223582 CR615122 BQ427883 BU147262 BG470951 BC005004 BF686195 
    BQ945905 BQ671757 AI564017 BU195484 BQ068758 CF264872 CR607871 BX354777 
    BM788041 CR590914 BU150778 BU151006 BU192798 BI869839 CF146548 BE790829 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM64A (see all 12)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b
    SP1:                          -     -                       -     -     -     -           -     -               
    SP2:                          -     -                       -     -     -     -                                 
    SP3:                          -     -                       -     -     -     -                                 
    SP4:                          -     -                       -     -     -     -     -     -     -               
    SP5:                                -                                                                           


    ECgene alternative splicing isoforms for FAM64A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM64A expression in normal human tissues (normalized intensities)      FAM64A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGACTTTCCT
    FAM64A Expression
    About this image


    FAM64A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Neural Tube (Nervous System)    fully expand to see all 5 entries
             Metencephalon
     
     NULL (Uncategorized)
             Mesenchymal Progenitor Cells - Passage 2
     
     Brain (Nervous System)
             Medulla Oblongata
    FAM64A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM64A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.592116

    UniProtKB/Swiss-Prot: FA64A_HUMAN, Q9BSJ6
    Tissue specificity: Expressed in thymus (at protein level). Detected in spleen, colon, ovary and small intestines

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM64A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FAM64A gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam64a1 , 5 family with sequence similarity 64, member A1, 5 77.54(n)1
    74.78(a)1
      11 (43.81 cM)5
    1092121  NM_144526.31  NP_653109.21 
     720420325 
    chicken
    (Gallus gallus)
    Aves FAM64A6
    family with sequence similarity 64, member A
    22(a)
    1 ↔ 1
    19(9882255-9890764)


    ENSEMBL Gene Tree for FAM64A (if available)
    TreeFam Gene Tree for FAM64A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM64A gene

    FAM64A for paralogs           About GeneDecksing


    4 Pseudogenes.org Pseudogenes for FAM64A
    PGOHUM00000240483 PGOHUM00000245486 PGOHUM00000245643 PGOHUM00000243708


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM64A (see all 243)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1867846321,2
    --6345744(+) AGTGAC/TACGTA 2 -- us2k10--------
    rs596382511,2
    --6345758(+) AATTAA/CTTACA 2 -- us2k10--------
    rs1397197471,2
    --6345845(+) AGGAGC/GACTGC 2 -- us2k10--------
    rs1916135251,2
    --6345892(+) TTGTAC/TCACTG 2 -- us2k10--------
    rs1824906701,2
    --6345992(+) CCTACA/GAAATG 2 -- us2k10--------
    rs98931871,2
    C,F,H--6346031(+) ctttcC/Ttcatt 2 -- us2k1 trp36Minor allele frequency- T:0.04NS EA WA 516
    rs98932101,2
    C,F,H--6346068(+) aaaaaT/Cgacga 2 -- us2k1 tfbs314Minor allele frequency- C:0.07NS EA NA WA CSA 754
    rs1871822911,2
    --6346071(+) AACGAC/TGACTT 2 -- us2k10--------
    rs98917711,2
    C,A,H--6346173(+) tttgcA/Gtttga 2 -- us2k1 tfbs311Minor allele frequency- G:0.08NA WA CSA EA 376
    rs98943251,2
    C,A,H--6346179(+) tttgaT/Atttat 2 -- us2k1 tfbs312Minor allele frequency- A:0.09NA WA CSA EA 378

    HapMap Linkage Disequilibrium report for FAM64A (6347735 - 6354789 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FAM64A: --
    Human Gene Mutation Database (HGMD): FAM64A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM64A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM64A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    FAM64A for disorders           About GeneDecksing


    Export disorders for FAM64A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM64A gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with FAM64A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The CALM and CALM/AF10 interactor CATS is a marker for proliferation. (PubMed id 19383357)1, 2, 3 Archangelo L.F.... Bohlander S.K. (Mol. Oncol. 2008)
    2. The novel CALM interactor CATS influences the subcellular localization of the leukemogenic fusion protein CALM/AF10. (PubMed id 16491119)1, 2, 3 Archangelo L.F.... Bohlander S.K. (Oncogene 2006)
    3. The CATS (FAM64A) protein is a substrate of the kinase interacting stathmin (KIS). (PubMed id 23419774)1, 2 Archangelo L.F.... Saad S.T. (Biochim. Biophys. Acta 2013)
    4. RCS1, a substrate of APC/C, controls the metaphase to anaphase transition. (PubMed id 18757745)1, 2 Zhao W.M....Fang G. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    10. Protein microarray analysis identifies human cellular prion protein interactors. (PubMed id 18482256)1 Satoh J....Tabunoki H. (Neuropathol. Appl. Neurobiol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54478 HGNC: 25483 AceView: FLJ10156 Ensembl:ENSG00000129195 euGenes: HUgn54478
    ECgene: FAM64A H-InvDB: FAM64A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM64A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM64A gene:
    Search GeneIP for patents involving FAM64A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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