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Aliases for FAM63A Gene

Aliases for FAM63A Gene

  • Family With Sequence Similarity 63, Member A 2 3
  • KIAA1390 4

External Ids for FAM63A Gene

Previous GeneCards Identifiers for FAM63A Gene

  • GC01M147782
  • GC01M149232
  • GC01M122346

Summaries for FAM63A Gene

GeneCards Summary for FAM63A Gene

FAM63A (Family With Sequence Similarity 63, Member A) is a Protein Coding gene. An important paralog of this gene is FAM63B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM63A Gene

Genomics for FAM63A Gene

Regulatory Elements for FAM63A Gene

Genomic Location for FAM63A Gene

150,996,086 bp from pter
151,008,378 bp from pter
12,293 bases
Minus strand

Genomic View for FAM63A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM63A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM63A Gene

Proteins for FAM63A Gene

  • Protein details for FAM63A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM63A
    Protein Accession:
    Secondary Accessions:
    • B3KWP4
    • B3KWV8
    • B4DXF2
    • B4E1S4
    • D3DV09
    • J3KP53
    • Q5SZF0
    • Q9NUL9
    • Q9P2F7

    Protein attributes for FAM63A Gene

    469 amino acids
    Molecular mass:
    51778 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA92628.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM63A Gene


neXtProt entry for FAM63A Gene

Proteomics data for FAM63A Gene at MOPED

Post-translational modifications for FAM63A Gene

  • Ubiquitination at Lys255
  • Modification sites at PhosphoSitePlus

Antibody Products

No data available for DME Specific Peptides for FAM63A Gene

Domains for FAM63A Gene

Protein Domains for FAM63A Gene


Suggested Antigen Peptide Sequences for FAM63A Gene

Graphical View of Domain Structure for InterPro Entry



  • Q8N5J2
  • Belongs to the FAM63 family.
genes like me logo Genes that share domains with FAM63A: view

No data available for Gene Families for FAM63A Gene

Function for FAM63A Gene

Gene Ontology (GO) - Molecular Function for FAM63A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM63A: view
genes like me logo Genes that share phenotypes with FAM63A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM63A Gene

Localization for FAM63A Gene

Subcellular locations from

Jensen Localization Image for FAM63A Gene COMPARTMENTS Subcellular localization image for FAM63A gene
Compartment Confidence
cytosol 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM63A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with FAM63A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM63A Gene

Pathways for FAM63A Gene

SuperPathways for FAM63A Gene

No Data Available

Interacting Proteins for FAM63A Gene

Gene Ontology (GO) - Biological Process for FAM63A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with FAM63A: view

No data available for Pathways by source for FAM63A Gene

Transcripts for FAM63A Gene

Unigene Clusters for FAM63A Gene

Family with sequence similarity 63, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM63A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM63A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b · 11c
SP1: - - - -
SP2: - - -
SP3: -
SP4: - - - - - -
SP5: - -
SP6: -

Relevant External Links for FAM63A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM63A Gene

mRNA expression in normal human tissues for FAM63A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM63A Gene

This gene is overexpressed in Whole Blood (5.1).

Protein differential expression in normal tissues for FAM63A Gene

This gene is overexpressed in Peripheral blood mononuclear cells (27.3), Platelet (15.6), and Spinal cord (6.7).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM63A Gene

SOURCE GeneReport for Unigene cluster for FAM63A Gene Hs.743952

genes like me logo Genes that share expressions with FAM63A: view

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt and Expression partners for FAM63A Gene

Orthologs for FAM63A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for FAM63A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM63A 35
  • 85.65 (n)
  • 85.87 (a)
FAM63A 36
  • 85 (a)
(Canis familiaris)
Mammalia FAM63A 35
  • 87.73 (n)
  • 85.28 (a)
FAM63A 36
  • 83 (a)
(Mus musculus)
Mammalia Fam63a 35
  • 84.01 (n)
  • 86.51 (a)
Fam63a 16
Fam63a 36
  • 85 (a)
(Pan troglodytes)
Mammalia FAM63A 35
  • 99.42 (n)
  • 98.84 (a)
FAM63A 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Fam63a 35
  • 83.65 (n)
  • 84.58 (a)
(Monodelphis domestica)
Mammalia FAM63A 36
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 42 (a)
(Gallus gallus)
Aves LOC100857795 35
  • 73.25 (n)
  • 77.5 (a)
FAM63A 36
  • 65 (a)
(Anolis carolinensis)
Reptilia FAM63A 36
  • 47 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam63a 35
  • 69.21 (n)
  • 72.24 (a)
(Danio rerio)
Actinopterygii fam63a 35
  • 66.07 (n)
  • 66.16 (a)
fam63a 36
  • 49 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.877 35
(Caenorhabditis elegans)
Secernentea Y55F3AM.9 36
  • 31 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 22 (a)
-- 36
  • 25 (a)
-- 38
(Oryza sativa)
Liliopsida Os.20605 35
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1538 36
  • 49 (a)
Species with no ortholog for FAM63A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM63A Gene

Gene Tree for FAM63A (if available)
Gene Tree for FAM63A (if available)

Paralogs for FAM63A Gene

Paralogs for FAM63A Gene

Selected SIMAP similar genes for FAM63A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM63A: view

Variants for FAM63A Gene

Sequence variations from dbSNP and Humsavar for FAM63A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs708909 -- 151,000,062(+) ACCCT(A/G)TGATG intron-variant
rs771200 -- 150,996,382(+) ggcaa(C/T)acagc downstream-variant-500B
rs771201 -- 150,996,466(+) CCTCC(A/C/G/T)GCTTT downstream-variant-500B
rs771202 -- 150,997,091(+) CCTGG(A/G)TGGGA utr-variant-3-prime
rs771203 -- 151,001,038(+) CTCCC(A/G)CTTTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM63A Gene

Variant ID Type Subtype PubMed ID
nsv522317 CNV Loss 19592680
nsv522840 CNV Gain 19592680

Relevant External Links for FAM63A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM63A Gene

Disorders for FAM63A Gene

Relevant External Links for FAM63A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for FAM63A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM63A Gene

Publications for FAM63A Gene

  1. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PMID: 10718198) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. A protein interaction framework for human mRNA degradation. (PMID: 15231747) Lehner B. … Sanderson C.M. (Genome Res. 2004) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for FAM63A Gene

Sources for FAM63A Gene

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