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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

FAM63A Gene

protein-coding GIFtS: 49
GCID: GC01M150965

family with sequence similarity 63, member A

Explore 1 disease affiliated with
FAM63A via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Family With Sequence Similarity 63, Member A¹ ²
FLJ11280¹
RP11-316M1.5²
Protein FAM63A²
KIAA1390³

External Ids:	HGNC: 25648¹	Entrez Gene: 55793²	Ensembl: ENSG00000143409⁷	UniProtKB: Q8N5J2³

Export aliases for FAM63A gene to outside databases

Previous GC identifers: GC01M147782 GC01M149232 GC01M122346

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the FAM63A gene promoter:
STAT1 MAZR ARP-1 c-Myb IRF-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAM63A promoter sequence

Search SABiosciences Chromatin IP Primers for FAM63A

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM63A

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21.2

FAM63A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM63A gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M150965: view genomic region (about GC identifiers)

Start:	150,969,025 bp from pter	End:	150,980,854 bp from pter
Size:	11,830 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FA63A_HUMAN, Q8N5J2 (See protein sequence)

Recommended Name: Protein FAM63A

Size: 469 amino acids; 51778 Da

Sequence caution: Sequence=BAA92628.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: B3KWP4 B3KWV8 B4DXF2 B4E1S4 D3DV09 Q5SZF0 Q9NUL9 Q9P2F7

Alternative splicing: 4 isoforms: Q8N5J2-1 Q8N5J2-2 Q8N5J2-3 Q8N5J2-4

Explore the universe of human proteins at neXtProt for FAM63A: NX_Q8N5J2

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8N5J2

FAM63A Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (5 alternative transcripts):

NP_001035307.1 NP_001156730.1 NP_001156731.1 NP_001156732.1 NP_060849.2

ENSEMBL proteins:

ENSP00000310923 ENSP00000354814 ENSP00000354669 ENSP00000437174 ENSP00000451524

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: FAM63A Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for FAM63A
	GenScript Custom Purified and Recombinant Proteins Services for FAM63A
	Novus Biologicals FAM63A Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for FAM63A

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--

FAM63A for ontologies About GeneDecksing

FAM63A Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	GenScript Custom Superior Antibodies Services for FAM63A
	Novus Biologicals FAM63A Antibodies
	Search for Antibodies for FAM63A at Abcam
	Uscn Antibodies for FAM63A
	ThermoFisher Antibodies for FAM63A

Assay Products for FAM63A:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for FAM63A
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for FAM63A

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

FAM63A for domains About GeneDecksing

1 InterPro domain/family:

IPR007518 DUF544

Graphical View of Domain Structure for InterPro Entry Q8N5J2

ProtoNet protein and cluster: Q8N5J2

UniProtKB/Swiss-Prot: FA63A_HUMAN, Q8N5J2

Similarity: Belongs to the FAM63 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 5): FAM63A Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM63A
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM63A:
		hsa-miR-3910 hsa-miR-1266 hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-874
		SwitchGear 3'UTR luciferase reporter plasmid: FAM63A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM63A (see all 4) OriGene shRNA RFP: FAM63A OriGene siRNA: FAM63A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM63A

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for FAM63A

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM63A (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM63A (see all 6) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 5): FAM63A (NM_001040217)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM63A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM63A

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for FAM63A
		Search LifeMap BioReagents cell lines for FAM63A

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM63A

3 GenomeRNAi human phenotypes for FAM63A:

Increased gamma-H2AX phosphory

Small cells

Synthetic lethal with Ras

Animal Models:
7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Fam63a):

behavior/neurological	hematopoietic system	homeostasis/metabolism	immune system	limbs/digits/tail
other	skeleton

FAM63A for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for FAM63A

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5/12 Interacting proteins for FAM63A (Q8N5J2^{1, 3} ENSP00000354814⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NAA38	O95777¹^,³, ENSP00000249299⁴	EBI-372322,EBI-347779 I2D: score=4 STRING: ENSP00000249299
CSNK1G2	P78368³	I2D: score=2
MMS19	Q96T76³	I2D: score=2
ACOX1	Q15067³	I2D: score=1
DIAPH1	O60610³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

FAM63A for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for FAM63A
Search CenterWatch for drugs/clinical trials and news about FAM63A / FA63A

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for FAM63A gene (5 alternative transcripts):

NM_001040217.2 NM_001163258.1 NM_001163259.1 NM_001163260.1 NM_018379.4

Unigene Cluster for FAM63A:

Family with sequence similarity 63, member A

Hs.743952 [show with all ESTs]

Unigene Representative Sequence: AB037811

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000312210(uc001ewc.3 uc001ewd.3) ENST00000361936(uc010pcm.2 uc001ewf.3 uc010pcn.2 uc001ewg.3)

ENST00000361738 ENST00000493834 ENST00000497067 ENST00000470877

miRNA Products:		OriGene 3'-UTR Clone (see all 5): FAM63A Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM63A
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM63A:
		hsa-miR-3910 hsa-miR-1266 hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-874
		SwitchGear 3'UTR luciferase reporter plasmid: FAM63A 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM63A (see all 4) OriGene shRNA RFP: FAM63A OriGene siRNA: FAM63A
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM63A

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM63A (see all 8) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM63A (see all 6) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 5): FAM63A (NM_001040217)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM63A
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM63A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM63A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FAM63A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM63A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM63A

Additional cDNA sequence:

AB037811.1 AK002142.1 AK125493.1 AK125959.1 AK301946.1 AK303962.1 BC014447.1 BC032321.1

BC075812.1

11 DOTS entries:

DT.91756435 DT.100757406 DT.95275458 DT.92028140 DT.121440650 DT.121440675 DT.91756436 DT.91756439

DT.95275464 DT.91756437 DT.97785732

24/102 AceView cDNA sequences (see all 102):

AK125959 CR594376 AA384330 BI822522 AL520489 AI963989 BI764092 BU074471

AB037811 BM851226 BM152677 AU158795 AL521015 BI912829 BX499560 AL707057

BU074294 AL520488 AK125493 BP361357 BC014447 CD244208 AL040235 BI761931

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FAM63A (see all 8) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	·	3c	·	3d	·	3e	^	4	^	5	^	6	^	7	^	8a	·	8b	·	8c	^	9a	·	9b	^	10	^	11a	·	11b	·	11c
SP1:									-		-		-		-
SP2:									-		-		-
SP3:									-
SP4:									-		-		-		-		-		-
SP5:									-		-

ECgene alternative splicing isoforms for FAM63A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

FAM63A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGGGCGCCT

About this image

FAM63A expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Mandibular Condyle

Bone

Mandibular Fossa

Bone

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See FAM63A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM63A

SOURCE GeneReport for Unigene cluster: Hs.743952

SABiosciences Custom PCR Arrays for FAM63A

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM63A Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat FAM63A
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM63A
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM63A

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM63A

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for FAM63A gene from 6/23 species (see all 23) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	LOC100857795¹	protein FAM63A-like	71.41(n) 74.41(a)		100857795 XM_003642694.1 XP_003642742.1
lizard (Anolis carolinensis)	Reptilia	FAM63A⁶	--	76(a)	1 ↔ 1	GL344087.1(12379-18782)
zebrafish (Danio rerio)	Actinopterygii	fam63a¹	family with sequence similarity 63, member A	60.04(n) 55.74(a)		563470 NM_001100011.1 NP_001093481.1
worm (Caenorhabditis elegans)	Secernentea	Y55F3AM.9¹	Protein Y55F3AM.9	48.03(n) 41.34(a)		176920 NM_067622.3 NP_500023.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT4G11860¹	hypothetical protein	49.35(n) 43.81(a)		826793 NM_117256.2 NP_567383.1
rice (Oryza sativa)	Liliopsida	Os.20605²	Oryza sativa (japonica cultivar-group) cDNA clone0 more	73.93(n)		AK067573.1

ENSEMBL Gene Tree for FAM63A (if available)
TreeFam Gene Tree for FAM63A (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for FAM63A gene

FAM63B²

1 SIMAP similar gene for FAM63A using alignment to 4 protein entries: FA63A_HUMAN (see all proteins):

FAM63B

FAM63A for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs139261422^1,2	C,	--	150977208(+)	`TCTCA-/AAAATA AAATAAAATAAAAT`	5	--	int¹		0	--	--	--	--
rs36202690^1,2	--	--	150977208(+)	`AAAAT-/AAAA TAAAATAAAAT`	1	--	int¹		0	--	--	--	--
rs71090115^1,2	--	--	150968877(+)	`AAAAA-/AGAAAA`	5	--	int¹		1		NA	2
rs34936260^1,2	--	--	150977215(+)	`AATAA-/AATA AAATAAAATAA`	1	--	int¹		0	--	--	--	--
rs5777752^1,2	--	--	150977216(+)	`ataaa-/ATAA AATAAAttaaa`	1	--	int¹		0	--	--	--	--
rs200868152^1,2	--	--	150977208(+)	`TCTCA-/AAAA TAAAATAAAAT`	1	--	int¹		0	--	--	--	--
rs36206887^1,2	--	--	150977216(+)	`ATAAA-/ATAA AATAAAATAAA`	5	--	int¹		0	--	--	--	--
rs3034013^1,2	--	--	150977212(-)	`tttta-/TTTTA ttttt`	5	--	int¹		0	--	--	--	--
rs71807894^1,2	--	--	150977210(+)	`AATAA-/AATAA AATAA`	1	--	int¹		0	--	--	--	--
rs5777749^1,2	--	--	150977211(+)	`ataaa-/ATAAA ataaa`	1	--	int¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for FAM63A (150969025 - 150980854 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM63A: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM63A

DNA2.0 Custom Variant and Variant Library Synthesis for FAM63A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

FAM63A for disorders About GeneDecksing

1 disease for FAM63A: About MalaCards

kidney disease

Human Genome Epidemiology (HuGE) Navigator: FAM63A (1 document)

Export disorders for FAM63A gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for FAM63A gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with FAM63A)

Utopia: connect your pdf to the dynamic
world of online information

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)^{1, 2, 3} Nagase T.... Ohara O. (2000)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
New loci associated with kidney function and chronic kidney disease. (PubMed id 20383146)¹ KAPttgen A....Fox C.S. (2010)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)² Dephoure N.... Gygi S.P. (2008)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 55793	HGNC: 25648	AceView: FLJ11280	Ensembl:ENSG00000143409	euGenes: HUgn55793
ECgene: FAM63A	H-InvDB: FAM63A

(According to HUGE)
About This Section

HUGE: KIAA1390

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for FAM63A	Pharmacogenomics, SNPs, Pathways

Intellectual Property for FAM63A gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for FAM63A gene:
Search GeneIP for patents involving FAM63A

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	Browse OriGene Antibodies		OriGene shRNA RFP for FAM63A
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM63A		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM63A
	Browse OriGene Protein Over-expression Lysates		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for FAM63A		OriGene 3'-UTR Clone for FAM63A
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM63A		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM63A
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for FAM63A		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for FAM63A		OriGene Custom Protein Services for FAM63A
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM63A
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM63A
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM63A
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM63A
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM63A
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM63A

	GenScript Custom Purified and Recombinant Proteins Services for FAM63A		GenScript cDNA clones with any tag delivered in your preferred vector for FAM63A
	GenScript Custom Assay Services for FAM63A		GenScript Custom Superior Antibodies Services for FAM63A
	GenScript Custom overexpressing Cell Line Services for FAM63A		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
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	Regulatory tfbs in FAM63A promoter
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FAM63A Proteins, Antibodies, CLIAs, and ELISAs

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM63A

	SwitchGear 3'UTR luciferase reporter plasmids for FAM63A
	SwitchGear Promoter luciferase reporter plasmids for FAM63A

ThermoFisher Antibodies for FAM63A

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM63A

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes FAM63A gene at Home site.

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FAM63A Gene

family with sequence similarity 63, member A

Aliases
for FAM63A gene

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for FAM63A gene

Genomic Views
for FAM63A gene

Proteins
for FAM63A gene

Protein Domains /
Families
for FAM63A gene

Function
for FAM63A gene

Pathways & Interactions
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Drugs & Compounds
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Transcripts
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Expression
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Orthologs
for FAM63A gene

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for FAM63A gene

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for FAM63A gene

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for FAM63A gene

External Searches for FAM63A gene

Genome Databases showing FAM63A gene

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FAM63A Gene

family with sequence similarity 63, member A

Aliasesfor FAM63A gene

Summariesfor FAM63A gene

Genomic Viewsfor FAM63A gene

Proteinsfor FAM63A gene

Protein Domains /Familiesfor FAM63A gene

Functionfor FAM63A gene

Pathways & Interactionsfor FAM63A gene

Drugs & Compoundsfor FAM63A gene

Transcriptsfor FAM63A gene

Expression for FAM63A gene

Orthologsfor FAM63A gene

Paralogsfor FAM63A gene

Genomic Variantsfor FAM63A gene

Disorders / Diseasesfor FAM63A gene

Publicationsfor FAM63A gene

External Searches for FAM63A gene

Genome Databases showing FAM63A gene

Other Databases showing FAM63A gene

Specialized Databases showing FAM63A gene

Intellectual Propertyfor FAM63A gene

Productsfor FAM63A gene

View Random Gene

Aliases
for FAM63A gene

Summaries
for FAM63A gene

Genomic Views
for FAM63A gene

Proteins
for FAM63A gene

Protein Domains /
Families
for FAM63A gene

Function
for FAM63A gene

Pathways & Interactions
for FAM63A gene

Drugs & Compounds
for FAM63A gene

Transcripts
for FAM63A gene

Expression
for FAM63A gene

Orthologs
for FAM63A gene

Paralogs
for FAM63A gene

Genomic Variants
for FAM63A gene

Disorders / Diseases
for FAM63A gene

Publications
for FAM63A gene

Intellectual Property
for FAM63A gene

Products
for FAM63A gene