Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAM60A Gene

protein-coding   GIFtS: 49
GCID: GC12M031433

family with sequence similarity 60, member A

(Previous name: chromosome 12 open reading frame 14 )
(Previous symbol: C12orf14)
 Explore 7 diseases affiliated with
FAM60A via our new
 Human Malady Compendium 
Biological research products
for FAM60A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Family With Sequence Similarity 60, Member A1 2
C12orf141 2 3
TERA1 2
Tera Protein Homolog2 3
Chromosome 12 Open Reading Frame 141
Protein FAM60A2

External Ids:    HGNC: 307021   Entrez Gene: 585162   Ensembl: ENSG000001391467   OMIM: 6150275   UniProtKB: Q9NP503   

Export aliases for FAM60A gene to outside databases

Previous GC identifers: GC12M031325 GC12M031186


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: FA60A_HUMAN, Q9NP50
Function: Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes
encoding components of the TGF-beta signaling pathway

Gene Wiki entry for FAM60A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM60A gene promoter:
         Elk-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM60A promoter sequence
   Search SABiosciences Chromatin IP Primers for FAM60A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM60A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p11   Ensembl cytogenetic band:  12p11.21   HGNC cytogenetic band: 12p11.21

FAM60A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM60A gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M031433:  view genomic region     (about GC identifiers)

Start:
31,433,518 bp from pter      End:
31,479,992 bp from pter
Size:
46,475 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FA60A_HUMAN, Q9NP50 (See protein sequence)
Recommended Name: Protein FAM60A  
Size: 221 amino acids; 24852 Da
Subunit: Interacts with the Sin3/HDAC corepressor complex at least composed of BRMS1, BRMS1L, ING2, SAP30, SAP30L and
HDAC1
Subcellular location: Nucleus (Probable)
Secondary accessions: D3DUV8 Q9BSZ8
Alternative splicing: 2 isoforms:  Q9NP50-1   Q9NP50-2   

Explore the universe of human proteins at neXtProt for FAM60A: NX_Q9NP50

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NP50

  • FAM60A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001129283.1  NP_001129284.1  NP_067061.1  

    ENSEMBL proteins: 
     ENSP00000443697   ENSP00000337477   ENSP00000393279   ENSP00000443087   ENSP00000439952  
     ENSP00000443881   ENSP00000437363   ENSP00000379115  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate (see all 3): FAM60A
    OriGene Custom Protein Services for FAM60A 
    GenScript Custom Purified and Recombinant Proteins Services for FAM60A
    Novus Biologicals FAM60A Protein
    Novus Biologicals FAM60A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FAM60A

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016580Sin3 complex IDA--


    FAM60A for ontologies           About GeneDecksing



    FAM60A Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FAM60A 
    GenScript Custom Superior Antibodies Services for FAM60A
    Novus Biologicals FAM60A Antibodies
    Search for Antibodies for FAM60A at Abcam  
    Uscn Antibodies for FAM60A
    Search ThermoFisher Antibodies for FAM60A

    Assay Products for FAM60A: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FAM60A
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for FAM60A


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FAM60A for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR026065 FAM60A

    Graphical View of Domain Structure for InterPro Entry Q9NP50

    ProtoNet protein and cluster: Q9NP50

    UniProtKB/Swiss-Prot: FA60A_HUMAN, Q9NP50
    Similarity: Belongs to the FAM60 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: FA60A_HUMAN, Q9NP50
    Function: Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes
    encoding components of the TGF-beta signaling pathway
    Induction: Peaks during G1 and S phases of the cell cycle in U2OS cells. Up-regulated in squamous cell carcinoma (SCC),
    adenocarcinoma (AC), colon, ovary, rectum and stomach tumors

    miRNA
    Products:
        
    OriGene 3'-UTR Clone (see all 3): FAM60A
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM60A
    8/92 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM60A (see all 92):
    hsa-miR-640 hsa-miR-1321 hsa-miR-3194-5p hsa-miR-4272 hsa-miR-106a hsa-miR-199a-3p hsa-miR-15a hsa-miR-485-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM60A 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM60A (see all 4)
    OriGene shRNA RFP: FAM60A
    OriGene siRNA: FAM60A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM60A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FAM60A

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM60A (see all 6)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM60A (see all 4)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): FAM60A (NM_001135811)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM60A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM60A 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAM60A
    Search LifeMap BioReagents cell lines for FAM60A

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM60A

    2 GenomeRNAi human phenotypes for FAM60A:
     Decreased viability of wild-ty  Increased G1 DNA content 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM60A

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/6 Interacting proteins for FAM60A (Q9NP502, 3 ENSP000003374774) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GTPBP3Q969Y23, ENSP000003516444I2D: score=5 STRING: ENSP00000351644
    NMIQ132873I2D: score=1 
    PSMC2ENSP000002926444STRING: ENSP00000292644
    NDRG1ENSP000003199774STRING: ENSP00000319977
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030336negative regulation of cell migration IMP--


    FAM60A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAM60A
    Search CenterWatch for drugs/clinical trials and news about FAM60A / FA60A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAM60A gene (3 alternative transcripts): 
    NM_001135811.1  NM_001135812.1  NM_021238.2  

    Unigene Cluster for FAM60A:

    Family with sequence similarity 60, member A
    Hs.505154  [show with all ESTs]
    Unigene Representative Sequence: NM_001135811
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000448582(uc001rkc.3 uc010sjz.2) ENST00000539409 ENST00000337682(uc001rkd.3 uc010ska.2 uc001rke.3 uc010skb.2)
    ENST00000454658 ENST00000544921 ENST00000542983 ENST00000539004 ENST00000543615
    ENST00000536836 ENST00000395766

    miRNA
    Products:
         
    OriGene 3'-UTR Clone (see all 3): FAM60A
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAM60A
    8/92 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM60A (see all 92):
    hsa-miR-640 hsa-miR-1321 hsa-miR-3194-5p hsa-miR-4272 hsa-miR-106a hsa-miR-199a-3p hsa-miR-15a hsa-miR-485-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM60A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM60A (see all 4)
    OriGene shRNA RFP: FAM60A
    OriGene siRNA: FAM60A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM60A
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM60A (see all 6)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM60A (see all 4)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): FAM60A (NM_001135811)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM60A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM60A 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM60A
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM60A
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM60A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM60A

    Additional cDNA sequence: 

    AF087885.1 AF212220.1 AK026932.1 AK027736.1 AK294457.1 AL157432.1 AY598323.1 BC000024.2 
    BC004462.1 BC071966.1 BX648630.1 

    24/28 DOTS entries (see all 28):

    DT.117854  DT.100794304  DT.100673572  DT.100808260  DT.121126837  DT.100649258  DT.121126873  DT.95250842 
    DT.100794293  DT.121126879  DT.121126844  DT.121126852  DT.121126816  DT.75174382  DT.92448549  DT.100037389 
    DT.102843026  DT.121126853  DT.100794291  DT.121077379  DT.121126817  DT.121126827  DT.121126836  DT.121126880 

    24/431 AceView cDNA sequences (see all 431):

    AA227148 BM479347 AW271688 BE673689 AL532258 AI369761 AW237091 BC000024 
    BC071966 CA976079 BU634454 AA171799 AI587051 BF222943 AA227341 AL157432 
    BG481073 BU187601 AA401085 AA569870 BE302248 CA435293 BU192924 AI357687 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FAM60A (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b
    SP1:                                      -                                       
    SP2:                          -     -     -                                       
    SP3:                          -           -                                       
    SP4:                                                                              
    SP5:                                -     -                                       


    ECgene alternative splicing isoforms for FAM60A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAM60A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CACTTTGTAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See FAM60A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAM60A

    SOURCE GeneReport for Unigene cluster: Hs.505154
        SABiosciences Custom PCR Arrays for FAM60A
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM60A
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM60A
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM60A
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM60A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM60A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for FAM60A gene from 6/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam60a1 , 5 family with sequence similarity 60, member A1, 5 92.61(n)1
    97.74(a)1
      6 (78.67 cM)5
    563061  NM_019643.31  NP_062617.21 
     1489210355 
    chicken
    (Gallus gallus)
    Aves FAM60A1 family with sequence similarity 60, member A 83.64(n)
    91.82(a)
      418140  NM_001030766.1  NP_001025937.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM60A6
    --
    88(a)
    1 ↔ 1
    5(10809687-10814512)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.66972 Xenopus laevis transcribed sequence with weak similarity to protein refNP_067061.1 (H.sapiens) TERA protein [Homo sapiens] less 77.84(n)    BU901149.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc664592 zgc66459 76.82(n)   386721  BC055529.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG40681 CG4068 48.33(n)
    46.41(a)
      31424  NM_001103410.1  NP_001096880.1 


    ENSEMBL Gene Tree for FAM60A (if available)
    TreeFam Gene Tree for FAM60A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAM60A gene

    FAM60A for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for FAM60A
    PGOHUM00000262878 PGOHUM00000262879 PGOHUM00000234904 PGOHUM00000234941 PGOHUM00000249270


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/825 NCBI SNPs in FAM60A are shown (see all 825    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1807360871,2
    --31433039(+) TTTCCC/TAGGTA 3 -- int10--------
    rs1863185591,2
    --31433042(+) CCCAGA/GTAATA 3 -- int10--------
    rs1435288971,2
    --31433116(+) AAGTAC/GATATT 3 -- int10--------
    rs1466519991,2
    --31433191(+) CAACCA/CCTGAT 3 -- int10--------
    rs781635881,2
    C,F,--31433219(+) TTTTAT/CAGTTT 3 -- int11Minor allele frequency- C:0.05EA 120
    rs1488271751,2
    --31433301(+) GGGAAC/GATTTT 3 -- int10--------
    rs1910223461,2
    --31433417(+) CCTTCA/TTGGCT 3 -- int10--------
    rs1831613781,2
    --31433803(+) AATCAC/TTTCAA 3 -- ut310--------
    rs1142205291,2
    F,--31433844(+) TTTGTA/GATTCA 3 -- ut311Minor allele frequency- G:0.06WA 118
    rs1860506921,2
    --31434077(+) AAGGCA/TGGCAA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for FAM60A (31433518 - 31479992 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for FAM60A
         5 CNVs: 2976 8714 8716 3884 8717

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM60A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM60A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FAM60A for disorders           About GeneDecksing

    OMIM gene information: 615027    OMIM disorders: --

    7 diseases for FAM60A:    About MalaCards
    spondylolysis    squamous cell carcinoma    embryonal carcinoma    teratocarcinoma
    lung cancer    carcinoma    adenocarcinoma

    2 diseases from the University of Copenhagen DISEASES database for FAM60A:
    Spondylolysis     Photosensitivity disease
    Human Genome Epidemiology (HuGE) Navigator: FAM60A (1 document)

    Export disorders for FAM60A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAM60A gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with FAM60A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Family with sequence similarity 60A (FAM60A) protein is a cell cycle- fluctuating regulator of the SIN3-HDAC1 histone deacetylase complex. (PubMed id 22865885)1, 2, 3 Munoz I.M....Rouse J. (2012)
    2. Functional characterization of the human FAM60A protein: a new subunit of the Sin3 deacetylase complex. (PubMed id 22984288)1, 2, 3 Smith K.T.... Workman J.L. (2012)
    3. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    4. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)1, 2 Petroziello J.... Carter P. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)2 Matsuoka S.... Elledge S.J. (2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 58516 HGNC: 30702 AceView: C12orf14 Ensembl:ENSG00000139146 euGenes: HUgn58516
    ECgene: FAM60A H-InvDB: FAM60A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAM60A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FAM60A gene:
    Search GeneIP for patents involving FAM60A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for FAM60A  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM60A   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM60A  
     OriGene Protein Over-expression Lysate for FAM60A   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for FAM60A   OriGene 3'-UTR Clone for FAM60A  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM60A   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM60A  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FAM60A   OriGene Custom Protein Services for FAM60A  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM60A
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM60A
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM60A
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM60A
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM60A
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM60A
     GenScript Custom Purified and Recombinant Proteins Services for FAM60A GenScript cDNA clones with any tag delivered in your preferred vector for FAM60A
     GenScript Custom Assay Services for FAM60A GenScript Custom Superior Antibodies Services for FAM60A
     GenScript Custom overexpressing Cell Line Services for FAM60A CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in FAM60A promoter
     Search Chromatin IP Primers for FAM60A
     RT2 qPCR Primer Assay in human, mouse / rat FAM60A
     Search GNC Networks for FAM60A
     SABiosciences Custom PCR Arrays for FAM60A
     Search Tocris compounds for FAM60A
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     FAM60A antibodies
     FAM60A proteins
     FAM60A lysates
     Search for Antibodies for FAM60A at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for FAM60A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     FAM60A Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for FAM60A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM60A
     SwitchGear 3'UTR luciferase reporter plasmids for FAM60A
     SwitchGear Promoter luciferase reporter plasmids for FAM60A
     Search ThermoFisher Antibodies for FAM60A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM60A
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FAM60A gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4