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Aliases for FAM58BP Gene

Aliases for FAM58BP Gene

  • Family With Sequence Similarity 58, Member B, Pseudogene 2
  • FAM58B 3 4
  • Family With Sequence Similarity 58, Member B 2
  • Putative Cyclin-Related Protein FAM58B 3
  • Cyclin-Related Protein FAM58B 3

External Ids for FAM58BP Gene

Previous HGNC Symbols for FAM58BP Gene

  • FAM58B

Previous GeneCards Identifiers for FAM58BP Gene

  • GC01P200184

Summaries for FAM58BP Gene

GeneCards Summary for FAM58BP Gene

FAM58BP (Family With Sequence Similarity 58, Member B, Pseudogene) is a Pseudogene. GO annotations related to this gene include protein kinase binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM58BP Gene

Genomics for FAM58BP Gene

Genomic Location for FAM58BP Gene

Chromosome:
1
Start:
200,213,532 bp from pter
End:
200,214,774 bp from pter
Size:
1,243 bases
Orientation:
Plus strand

Genomic View for FAM58BP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for FAM58BP Gene

No data available for Regulatory Elements for FAM58BP Gene

Proteins for FAM58BP Gene

  • Protein details for FAM58BP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7Q3-FA58B_HUMAN
    Recommended name:
    Putative cyclin-related protein FAM58B
    Protein Accession:
    P0C7Q3

    Protein attributes for FAM58BP Gene

    Size:
    252 amino acids
    Molecular mass:
    28609 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM58BP Gene

Proteomics data for FAM58BP Gene at MOPED

Post-translational modifications for FAM58BP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM58BP Gene

Domains & Families for FAM58BP Gene

Protein Domains for FAM58BP Gene

Suggested Antigen Peptide Sequences for FAM58BP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0C7Q3

UniProtKB/Swiss-Prot:

FA58B_HUMAN :
  • Belongs to the cyclin family. Cyclin-like FAM58 subfamily.
Family:
  • Belongs to the cyclin family. Cyclin-like FAM58 subfamily.
genes like me logo Genes that share domains with FAM58BP: view

No data available for Gene Families for FAM58BP Gene

Function for FAM58BP Gene

Gene Ontology (GO) - Molecular Function for FAM58BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA --
GO:0019901 protein kinase binding IEA --
genes like me logo Genes that share ontologies with FAM58BP: view

Phenotypes for FAM58BP Gene

GenomeRNAi human phenotypes for FAM58BP:
genes like me logo Genes that share phenotypes with FAM58BP: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM58BP

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM58BP Gene

Localization for FAM58BP Gene

Gene Ontology (GO) - Cellular Components for FAM58BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA --
GO:0005634 nucleus IBA --
genes like me logo Genes that share ontologies with FAM58BP: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for FAM58BP Gene

Pathways & Interactions for FAM58BP Gene

SuperPathways for FAM58BP Gene

No Data Available

Interacting Proteins for FAM58BP Gene

Gene Ontology (GO) - Biological Process for FAM58BP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA --
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IBA --
GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain IBA --
genes like me logo Genes that share ontologies with FAM58BP: view

No data available for Pathways by source and SIGNOR curated interactions for FAM58BP Gene

Drugs & Compounds for FAM58BP Gene

No Compound Related Data Available

Transcripts for FAM58BP Gene

mRNA/cDNA for FAM58BP Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM58BP

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM58BP Gene

No ASD Table

Relevant External Links for FAM58BP Gene

GeneLoc Exon Structure for
FAM58BP
ECgene alternative splicing isoforms for
FAM58BP

Expression for FAM58BP Gene

mRNA expression in normal human tissues for FAM58BP Gene

mRNA differential expression in normal tissues according to GTEx for FAM58BP Gene

This gene is overexpressed in Testis (x46.3).

Protein differential expression in normal tissues from HIPED for FAM58BP Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM58BP Gene



mRNA Expression by UniProt/SwissProt for FAM58BP Gene

P0C7Q3-FA58B_HUMAN
Tissue specificity: Expressed in normal breast, breast cancer cell lines, healthy retina and retinoblastoma.
genes like me logo Genes that share expression patterns with FAM58BP: view

Protein tissue co-expression partners for FAM58BP Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for FAM58BP Gene

Orthologs for FAM58BP Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for FAM58BP Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Fam58b 16
Species with no ortholog for FAM58BP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM58BP Gene

ENSEMBL:
Gene Tree for FAM58BP (if available)
TreeFam:
Gene Tree for FAM58BP (if available)

Paralogs for FAM58BP Gene

(1) SIMAP similar genes for FAM58BP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM58BP: view

No data available for Paralogs for FAM58BP Gene

Variants for FAM58BP Gene

Sequence variations from dbSNP and Humsavar for FAM58BP Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
VAR_044332 -
VAR_044333 -

Structural Variations from Database of Genomic Variants (DGV) for FAM58BP Gene

Variant ID Type Subtype PubMed ID
nsv873093 CNV Gain 21882294

Relevant External Links for FAM58BP Gene

HapMap Linkage Disequilibrium report
FAM58BP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM58BP Gene

Disorders for FAM58BP Gene

Relevant External Links for FAM58BP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM58BP
genes like me logo Genes that share disorders with FAM58BP: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM58BP Gene

Publications for FAM58BP Gene

  1. KIF14 is a candidate oncogene in the 1q minimal region of genomic gain in multiple cancers. (PMID: 15897902) Corson T.W. … Gallie B.L. (Oncogene 2005) 2 67
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for FAM58BP Gene

Sources for FAM58BP Gene

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