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FAM58A Gene

protein-coding   GIFtS: 45
GCID: GC0XM152854

Family With Sequence Similarity 58, Member A

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 58, Member A1 2
Cyclin M1 2
STAR2 5
Cyclin-Related Protein FAM58A2
Cyclin-M3

External Ids:    HGNC: 284341   Entrez Gene: 920022   Ensembl: ENSG000001473827   OMIM: 3007085   UniProtKB: Q8N1B33   

Export aliases for FAM58A gene to outside databases

Previous GC identifers: GC0XM152375 GC0XM152506 GC0XM141511


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FAM58A Gene:
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests
syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a
cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative
splicing results in multiple transcript variants encoding distinct isoforms. (provided by RefSeq, Oct 2008)

GeneCards Summary for FAM58A Gene:
FAM58A (family with sequence similarity 58, member A) is a protein-coding gene. Diseases associated with FAM58A include star syndrome, and syndactyly. GO annotations related to this gene include protein kinase binding. An important paralog of this gene is CCNL2.

UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3
Function: May have a role in cell proliferation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011681.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM58A gene promoter:
         E2F-4   E2F-3a   E2F-5   Lmo2   E2F-2   E47   PPAR-alpha   E2F   E2F-1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM58A promoter sequence
   Search Chromatin IP Primers for FAM58A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM58A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

FAM58A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM58A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM152854:  view genomic region     (about GC identifiers)

Start:
152,853,377 bp from pter      End:
152,865,500 bp from pter
Size:
12,124 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3 (See protein sequence)
Recommended Name: Cyclin-related protein FAM58A  
Size: 248 amino acids; 28369 Da
Subunit: Interacts with SALL1
Sequence caution: Sequence=AAH01909.4; Type=Erroneous initiation; Sequence=AAH07232.4; Type=Erroneous initiation;
Sequence=AAH32121.1; Type=Erroneous initiation; Sequence=AAH71851.1; Type=Erroneous initiation;
Secondary accessions: Q2I380 Q330J9 Q96IU5 Q9BUU1
Alternative splicing: 2 isoforms:  Q8N1B3-1   Q8N1B3-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM58A: NX_Q8N1B3

Explore proteomics data for FAM58A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM58A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001124469.1  NP_689487.2  

    ENSEMBL proteins: 
     ENSP00000412865   ENSP00000402949   ENSP00000466345   ENSP00000384396  

    FAM58A Human Recombinant Protein Products:

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    Novus Biologicals FAM58A Lysate
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    Cloud-Clone Corp. Proteins for FAM58A

    FAM58A Antibody Products:

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    Search for Antibodies for FAM58A at Abcam
    Cloud-Clone Corp. Antibodies for FAM58A
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    Search LSBio for Antibodies for FAM58A

    FAM58A Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. CLIAs for FAM58A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR013763 Cyclin-like
     IPR006671 Cyclin_N
     IPR015429 Cyclin_C/H/T/L
     IPR028759 Cyclin-rel_FAM58

    Graphical View of Domain Structure for InterPro Entry Q8N1B3

    ProtoNet protein and cluster: Q8N1B3

    UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3
    Similarity: Belongs to the cyclin family. Cyclin-like FAM58 subfamily


    FAM58A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FA58A_HUMAN, Q8N1B3
    Function: May have a role in cell proliferation

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18297069
    GO:0019901protein kinase binding IEA--
         
    FAM58A for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM58A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM58A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM58A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM58A

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM58A:
    hsa-mir-92a-3p (MIRT049686), hsa-mir-92b-3p (MIRT040674)

    Block miRNA regulation of human, mouse, rat FAM58A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM58A (see all 12):
    hsa-miR-766 hsa-miR-942 hsa-miR-9 hsa-miR-2355-5p hsa-miR-466 hsa-miR-130b* hsa-miR-1207-3p hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidFAM58A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM58A

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): FAM58A (NM_001130997)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM58A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM58A

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM58A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    golgi apparatus1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM58A
    Interactions:

        Search GeneGlobe Interaction Network for FAM58A

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--

    FAM58A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM58A (FA58A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FAM58A gene (2 alternative transcripts): 
    NM_001130997.2  NM_152274.4  

    Unigene Cluster for FAM58A:

    Family with sequence similarity 58, member A
    Hs.496943  [show with all ESTs]
    Unigene Representative Sequence: BM473242
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370175(uc011myr.2 uc011mys.2) ENST00000470284 ENST00000370173
    ENST00000370171 ENST00000276345 ENST00000429336 ENST00000440428 ENST00000428722
    ENST00000465867 ENST00000482182 ENST00000406277

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM58A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM58A (see all 12):
    hsa-miR-766 hsa-miR-942 hsa-miR-9 hsa-miR-2355-5p hsa-miR-466 hsa-miR-130b* hsa-miR-1207-3p hsa-miR-3119
    SwitchGear 3'UTR luciferase reporter plasmidFAM58A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM58A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM58A
    Clone
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    OriGene clones in human, mouse for FAM58A (see all 16)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): FAM58A (NM_001130997)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM58A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM58A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAM58A
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM58A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM58A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM58A
      QuantiFast Probe-based Assays in human, mouse, rat FAM58A

    Additional mRNA sequence: 

    AY445048.1 BC001909.1 BC007232.1 BC032121.2 BC071851.1 DQ323993.1 

    9 DOTS entries:

    DT.403010  DT.100754240  DT.97844703  DT.121316730  DT.121316755  DT.95285215  DT.75102854  DT.91764825 
    DT.95285212 

    Selected AceView cDNA sequences (see all 149):

    BM785505 AI564254 AW079353 CA307663 AW675396 AW009759 AI368788 CR623450 
    BQ052733 BC071851 BM708687 AL544688 CB529466 BE646636 CF529839 BE395987 
    BQ669511 BQ670735 BU634035 AI559684 CF529621 BU685137 BQ000249 BE378495 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for FAM58A    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e
    SP1:                                                  -                           
    SP2:                                                  -                           
    SP3:                                                                              
    SP4:        -     -     -                                                         
    SP5:                                      -           -                           


    ECgene alternative splicing isoforms for FAM58A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM58A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FAM58A Expression
    About this image

    FAM58A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM58A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.496943
        Custom PCR Arrays for FAM58A
    Primer
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    OriGene qPCR primer pairs and template standards for FAM58A
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    QuantiFast Probe-based Assays in human, mouse, rat FAM58A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM58A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for FAM58A gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam58b1 family with sequence similarity 58, member B 86.64(n)
    91.81(a)
      69109  NM_197989.1  NP_932106.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM58A6
    family with sequence similarity 58, member A
    74(a)
    1 ↔ 1
    2(87148632-87161456)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.329442 Xenopus laevis transcribed sequence with weak similarity more 72.39(n)    BJ617355.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fam58a1 family with sequence similarity 58, member A 64.7(n)
    64.09(a)
      553650  NM_001020623.1  NP_001018459.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta koko1 kokopelli 54.09(n)
    38.21(a)
      14462485  NM_169812.3  NP_732339.1 
    worm
    (Caenorhabditis elegans)
    Secernentea cic-16
    Protein CIC-1 (cic-1) mRNA, complete cds
    14(a)
    many ↔ many
    III(2394329-2401308) WBGene00000506
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SSN86
    Cyclin-like component of the RNA polymerase II hol...
    13(a)
    1 → many
    XIV(584320-585291) YNL025C


    ENSEMBL Gene Tree for FAM58A (if available)
    TreeFam Gene Tree for FAM58A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM58A gene
    CCNL22  CCNT22  CCNK2  CCNC2  CCNL12  CCNT12  
    4 SIMAP similar genes for FAM58A using alignment to 6 protein entries:     FA58A_HUMAN (see all proteins):
    FAM58BP    CCNK    CCNL2    CCNL1

    FAM58A for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FAM58A
    PGOHUM00000250063


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM58A (see all 231)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1911351211,2
    --152721060(+) CGTACA/GTCTAG 2 -- ds50010--------
    rs1807951841,2
    --152721097(+) CCTGGA/TCTGGT 2 -- ds50010--------
    rs2022129881,2
    --152721129(+) TTGAG-/CAAGGAG 2 -- ds50010--------
    rs1854665171,2
    --152721156(+) GGGCCA/CCAGCT 2 -- ds50010--------
    rs1401110211,2
    --152721288(+) CCTGCC/TGCCTG 2 -- ds50010--------
    rs1914009201,2
    --152721289(+) CTGCCA/GCCTGA 2 -- ds50010--------
    rs1112263621,2
    C,F--152721381(+) CTGCAA/GAGCAA 2 -- ds50011Minor allele frequency- G:0.00NA 1
    rs583997621,2
    C,F--152721393(+) GCCAAA/GGGTCC 2 -- ds50012Minor allele frequency- G:0.00WA 4
    rs1828160081,2
    C--152721443(+) TCAGCC/TACGTT 2 -- ut310--------
    rs1490688801,2
    --152721446(+) GCCACA/GTTGCA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for FAM58A (152853377 - 152865500 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for FAM58A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv33199CNV Gain+Loss17666407

    Human Gene Mutation Database (HGMD): FAM58A
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM58A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM58A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300708   
    OMIM disorders: 300707  
    UniProtKB/Swiss-Prot: FA58A_HUMAN, Q8N1B3
  • Toe syndactyly, telecanthus, and anogenital and renal malformations (STAR) [MIM:300707]: A syndrome
    characterized by anal, genital and renal tract anomalies, facial dysmorphism and syndactyly. Features include
    anal stenosis, a rectovaginal fistula, clitoral hypertrophy, a pelvic right kidney, toe syndactyly, and
    telecanthus. Note=The disease is caused by mutations affecting the gene represented in this entry

  • 7 diseases for FAM58A:    About MalaCards
    star syndrome    syndactyly    brachydactyly    parkinson's disease
    malaria    multiple myeloma    myeloma

    2 diseases from the University of Copenhagen DISEASES database for FAM58A:
    Brachydactyly     Syndactyly

    FAM58A for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for FAM58A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM58A gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with FAM58A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Mutations in the cyclin family member FAM58A cause an X-linked dominant disorder characterized by syndactyly, telecanthus and anogenital and renal malformations. (PubMed id 18297069)1, 2, 3 Unger S....Kohlhase J. (Nat. Genet. 2008)
    2. CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. (PubMed id 24218572)1, 3 Guen V.J....Colas P. (Proc. Natl. Acad. Sci. U.S.A. 2013)
    3. A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. (PubMed id 22961080)1 Li H....Lin X. (Diabetes 2013)
    4. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    5. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    6. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    9. Identification of genes related to Parkinson's disease using expressed sequence tags. (PubMed id 17213182)1 Kim J.M.... Kim N.S. (DNA Res. 2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 92002 HGNC: 28434 AceView: MGC29729 Ensembl:ENSG00000147382 euGenes: HUgn92002
    ECgene: FAM58A H-InvDB: FAM58A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FAM58A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM58A gene:
    Search GeneIP for patents involving FAM58A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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