Aliases for FAM58A Gene
External Ids for FAM58A Gene
Previous GeneCards Identifiers for FAM58A Gene
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
GeneCards Summary for FAM58A Gene
FAM58A (Family With Sequence Similarity 58 Member A) is a Protein Coding gene. Diseases associated with FAM58A include Star Syndrome and Syndactyly. GO annotations related to this gene include protein kinase binding and protein kinase activator activity. An important paralog of this gene is CCNT2.
UniProtKB/Swiss-Prot for FAM58A Gene
Activating cyclin for the cyclin-associated kinase CDK10.