Aliases for FAM58A Gene
External Ids for FAM58A Gene
Previous GeneCards Identifiers for FAM58A Gene
Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
GeneCards Summary for FAM58A Gene
FAM58A (Family With Sequence Similarity 58 Member A) is a Protein Coding gene. Diseases associated with FAM58A include star syndrome and syndactyly. Among its related pathways are Metabolism and Corticotropin-releasing hormone. GO annotations related to this gene include protein kinase binding and protein kinase activator activity. An important paralog of this gene is CCNT2.
UniProtKB/Swiss-Prot for FAM58A Gene
Activating cyclin for the cyclin-associated kinase CDK10.