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FAM49B Gene

protein-coding   GIFtS: 51
GCID: GC08M130853

Family With Sequence Similarity 49, Member B

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 49, Member B1 2
L12 3
Protein FAM49B2

External Ids:    HGNC: 252161   Entrez Gene: 515712   Ensembl: ENSG000001533107   UniProtKB: Q9NUQ93   

Export aliases for FAM49B gene to outside databases

Previous GC identifers: GC08M130922 GC08M126172


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM49B Gene:
FAM49B (family with sequence similarity 49, member B) is a protein-coding gene. An important paralog of this gene is FAM49A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM49B gene promoter:
         AML1a   HNF-4alpha2   STAT5A   POU3F2   HNF-4alpha1   FOXO1a   NF-kappaB1   ATF6   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAM49B promoter sequence
   Search Chromatin IP Primers for FAM49B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM49B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.21   Ensembl cytogenetic band:  8q24.21   HGNC cytogenetic band: 8q24

FAM49B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM49B gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M130853:  view genomic region     (about GC identifiers)

Start:
130,851,839 bp from pter      End:
131,029,375 bp from pter
Size:
177,537 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: FA49B_HUMAN, Q9NUQ9 (See protein sequence)
Recommended Name: Protein FAM49B  
Size: 324 amino acids; 36748 Da
Sequence caution: Sequence=AAF64265.1; Type=Frameshift; Positions=65, 90, 126, 169, 172, 252, 292;
Secondary accessions: Q96AZ5 Q9NZE7

Explore the universe of human proteins at neXtProt for FAM49B: NX_Q9NUQ9

Explore proteomics data for FAM49B at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys199, Lys207, Lys213, Lys317
  • Modification sites at PhosphoSitePlus

  • See FAM49B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001243692.1  NP_057707.3  

    ENSEMBL proteins: 
     ENSP00000429150   ENSP00000428117   ENSP00000429802   ENSP00000384880   ENSP00000429078  
     ENSP00000429978   ENSP00000430674   ENSP00000429499   ENSP00000430433   ENSP00000430806  
     ENSP00000429051   ENSP00000430694   ENSP00000429074   ENSP00000430127   ENSP00000429659  
     ENSP00000427994   ENSP00000430434   ENSP00000429860   ENSP00000430412  

    FAM49B Human Recombinant Protein Products:

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    Novus Biologicals FAM49B Proteins
    Novus Biologicals FAM49B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for FAM49B
    Cloud-Clone Corp. Proteins for FAM49B

     
    Search eBioscience for Proteins for FAM49B 

     
    antibodies-online proteins for FAM49B (5 products) 

     
    antibodies-online peptides for FAM49B

    FAM49B Antibody Products:

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    Abcam antibodies for FAM49B
    Cloud-Clone Corp. Antibodies for FAM49B
    Search ThermoFisher Antibodies for FAM49B
    LSBio Antibodies in human, mouse, rat for FAM49B
    antibodies-online antibodies for FAM49B (5 products) 

    FAM49B Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for FAM49B
    Cloud-Clone Corp. CLIAs for FAM49B
    Search eBioscience for ELISAs for FAM49B 
    antibodies-online kits for FAM49B (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009828 DUF1394

    Graphical View of Domain Structure for InterPro Entry Q9NUQ9

    ProtoNet protein and cluster: Q9NUQ9

    1 Blocks protein domain: IPB009828 Protein of unknown function DUF1394

    UniProtKB/Swiss-Prot: FA49B_HUMAN, Q9NUQ9
    Similarity: Belongs to the FAM49 family


    Find genes that share domains with FAM49B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for FAM49B:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM49B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM49B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM49B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM49B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM49B:
    hsa-let-7b-5p (MIRT032366), hsa-mir-27a-3p (MIRT028701), hsa-mir-128-3p (MIRT021970), hsa-mir-590-3p (MIRT016165), hsa-mir-26b-5p (MIRT029477), hsa-mir-769-5p (MIRT039184)

    Block miRNA regulation of human, mouse, rat FAM49B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM49B (see all 36):
    hsa-miR-429 hsa-miR-298 hsa-miR-3658 hsa-miR-3613-3p hsa-miR-29a* hsa-miR-34b hsa-miR-200b hsa-miR-616
    SwitchGear 3'UTR luciferase reporter plasmidFAM49B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM49B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM49B

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for FAM49B

    Clone
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    OriGene clones in human, mouse for FAM49B (see all 8)
    OriGene ORF clones in mouse, rat for FAM49B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM49B (NM_016623)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM49B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM49B

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAM49B
    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM49B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM49B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005929cilium IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    Find genes that share ontologies with FAM49B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM49B
    Interactions:

        Search GeneGlobe Interaction Network for FAM49B

    3 Interacting proteins for FAM49B (Q9NUQ92, 3) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166592, 3MINT-8261109 I2D: score=2 
    IKBKEQ141643I2D: score=1 
    UBA5Q9GZZ93I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM49B (FA49B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM49B gene (2 alternative transcripts): 
    NM_001256763.1  NM_016623.4  

    Unigene Cluster for FAM49B:

    Family with sequence similarity 49, member B
    Hs.126941  [show with all ESTs]
    Unigene Representative Sequence: NR_046359
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 28):
    ENST00000519824 ENST00000522746(uc003yss.3 uc003yst.3 uc003ysu.3)
    ENST00000523509(uc003ysw.3) ENST00000401979(uc003ysy.1) ENST00000519110(uc003ysx.3)
    ENST00000523288 ENST00000522250 ENST00000517654 ENST00000519540 ENST00000522941
    ENST00000520887 ENST00000517801 ENST00000519142 ENST00000518879 ENST00000522702
    ENST00000521223 ENST00000520204 ENST00000518283
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM49B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM49B (see all 36):
    hsa-miR-429 hsa-miR-298 hsa-miR-3658 hsa-miR-3613-3p hsa-miR-29a* hsa-miR-34b hsa-miR-200b hsa-miR-616
    SwitchGear 3'UTR luciferase reporter plasmidFAM49B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM49B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM49B
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM49B (see all 8)
    OriGene ORF clones in mouse, rat for FAM49B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM49B (NM_016623)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM49B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM49B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAM49B
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM49B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM49B
      QuantiTect SYBR Green Assays in human, mouse, rat FAM49B
      QuantiFast Probe-based Assays in human, mouse, rat FAM49B

    Additional mRNA sequence: 

    AF208851.1 AK001226.1 AK002059.1 AK130372.1 AY364259.1 AY598320.1 BC003599.1 BC016345.1 
    BC017297.2 NR_046359.1 NR_046360.1 NR_046361.1 

    Selected DOTS entries (see all 28):

    DT.95157702  DT.100803737  DT.91758953  DT.100877218  DT.97792681  DT.86858455  DT.447993  DT.100877211 
    DT.100877215  DT.95157704  DT.120630615  DT.120630600  DT.95157710  DT.91684156  DT.95072934  DT.100877216 
    DT.120630646  DT.40234155  DT.75164023  DT.120630631  DT.120630727  DT.120630762  DT.75162209  DT.91757724 

    Selected AceView cDNA sequences (see all 358):

    BM994146 AI471217 CR616846 BI771469 BM838175 AW026220 CR597917 BM679687 
    BM876282 BP345150 R81190 BM510560 AA683182 AI159771 CR594067 AA864518 
    H80761 BE302362 AK001226 CB131479 H80760 N46629 AI298543 AA304806 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM49B (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16a · 16b
    SP1:                                                        -     -                                                                 -                           
    SP2:                                      -     -     -     -     -                                                                 -                           
    SP3:                          -           -     -     -     -     -                                                                 -                           
    SP4:                                            -     -     -     -                                                                 -                           
    SP5:                                                  -     -     -                                                                 -                           


    ECgene alternative splicing isoforms for FAM49B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM49B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTAAAGAAT
    FAM49B Expression
    About this image


    FAM49B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Brain (Nervous System)
             Cerebral Cortex
     
     Spleen (Hematopoietic System)
    FAM49B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM49B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.126941
        Custom PCR Arrays for FAM49B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FAM49B
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM49B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM49B
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    QuantiFast Probe-based Assays in human, mouse, rat FAM49B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM49B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM49B gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam49b1 , 5 family with sequence similarity 49, member B1, 5 94.75(n)1
    99.69(a)1
      15 (28.16 cM)5
    2236011  NM_144846.51  NP_659095.11 
     639290975 
    chicken
    (Gallus gallus)
    Aves FAM49B1 family with sequence similarity 49, member B 86.63(n)
    95.99(a)
      420330  XM_004940039.1  XP_004940096.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM49B6
    family with sequence similarity 49, member B
    99(a)
    1 ↔ 1
    4(3896739-3954368)
    African clawed frog
    (Xenopus laevis)
    Amphibia cg32066-prov2 hypothetical protein MGC52773 84.39(n)    BC042348.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufj85c112 wufj85c11 79.44(n)   337591  AY394961.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG320666
    --
    54(a)
    1 → many
    3L(10633386-10654113)
    worm
    (Caenorhabditis elegans)
    Secernentea R07G3.86
    Protein R07G3.8 (R07G3.8) mRNA, complete cds
    33(a)
    1 → many
    II(7618237-7620513) WBGene00019944


    ENSEMBL Gene Tree for FAM49B (if available)
    TreeFam Gene Tree for FAM49B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM49B gene
    FAM49A2  
    4 SIMAP similar genes for FAM49B using alignment to 12 protein entries:     FA49B_HUMAN (see all proteins):
    DKFZp686B04128    DKFZP566A1524    FAM49A    BM009

    Find genes that share paralogs with FAM49B           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for FAM49B
    PGOHUM00000240418


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM49B (see all 3504)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1170957621,2
    F--130851407(+) CTTTCA/TTAAAT 5 -- ds50011Minor allele frequency- T:0.02NA 120
    rs1806993091,2
    --130851441(+) AGTAGA/TGTGCA 5 -- ds50010--------
    rs1173995291,2
    F--130851444(+) AGTGTG/ACAAAT 5 -- ds50011Minor allele frequency- A:0.02NA 120
    rs78314431,2
    C,F,A,H--130851445(+) gtgtgC/Aaaatg 5 -- ds50016Minor allele frequency- A:0.09NS EA CSA WA 536
    rs1178320551,2
    C,F--130851476(+) CCATGC/TCTACC 5 -- ds50011Minor allele frequency- T:0.01NA 120
    rs1861394951,2
    --130851506(+) AAGGAC/GAGACA 5 -- ds50010--------
    rs746502651,2
    F--130851508(+) GGACAG/AACATG 5 -- ds50011Minor allele frequency- A:0.01NA 120
    rs169041561,2
    C,F--130851529(+) ATAGAG/ATTGGC 5 -- ds50014Minor allele frequency- A:0.01NA WA 258
    rs1501079131,2
    C--130851536(+) TGGCAA/GAGAAG 5 -- ds50010--------
    rs1455296951,2
    --130851690(+) GGATCC/TAGTGG 5 -- ds50010--------

    HapMap Linkage Disequilibrium report for FAM49B (130851839 - 131029375 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for FAM49B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv268928CNV Insertion20981092
    nsv6396CNV Insertion18451855
    nsv398375CNV Insertion16902084
    esv1565412CNV Insertion17803354
    nsv521998CNV Loss19592680
    nsv524349CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM49B
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM49B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with FAM49B           About GenesLikeMe

    Genetic Association Database (GAD): FAM49B

    Export disorders for FAM49B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM49B gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with FAM49B)
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    1. A genome-wide association study identifies protein quantitative trait loci (pQTLs). (PubMed id 18464913)1, 4 Melzer D....Ferrucci L. (PLoS Genet. 2008)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder. (PubMed id 23726511)1 Xie P....Gelernter J. (Biol. Psychiatry 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Multiple loci are associated with white blood cell phenotypes. (PubMed id 21738480)1 Nalls M.A....Ganesh S.K. (PLoS Genet. 2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51571 HGNC: 25216 AceView: FAM49B Ensembl:ENSG00000153310 euGenes: HUgn51571
    ECgene: FAM49B H-InvDB: FAM49B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM49B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM49B gene:
    Search GeneIP for patents involving FAM49B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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