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Aliases for FAM49A Gene

Aliases for FAM49A Gene

  • Family With Sequence Similarity 49, Member A 2 3

External Ids for FAM49A Gene

Previous GeneCards Identifiers for FAM49A Gene

  • GC02M016653
  • GC02M016505

Summaries for FAM49A Gene

GeneCards Summary for FAM49A Gene

FAM49A (Family With Sequence Similarity 49, Member A) is a Protein Coding gene. An important paralog of this gene is FAM49B.

Gene Wiki entry for FAM49A Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM49A Gene

Genomics for FAM49A Gene

Regulatory Elements for FAM49A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM49A Gene

16,549,459 bp from pter
16,666,331 bp from pter
116,873 bases
Minus strand

Genomic View for FAM49A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM49A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM49A Gene

Proteins for FAM49A Gene

  • Protein details for FAM49A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM49A
    Protein Accession:
    Secondary Accessions:
    • B3KNZ1
    • Q53QW2

    Protein attributes for FAM49A Gene

    323 amino acids
    Molecular mass:
    37313 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM49A Gene

Proteomics data for FAM49A Gene at MOPED

Post-translational modifications for FAM49A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM49A Gene

Antibody Products

No data available for DME Specific Peptides for FAM49A Gene

Domains for FAM49A Gene

Protein Domains for FAM49A Gene


Suggested Antigen Peptide Sequences for FAM49A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM49 family.
  • Belongs to the FAM49 family.
genes like me logo Genes that share domains with FAM49A: view

No data available for Gene Families for FAM49A Gene

Function for FAM49A Gene

miRNA for FAM49A Gene

miRTarBase miRNAs that target FAM49A

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM49A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM49A Gene

Localization for FAM49A Gene

Subcellular locations from

Jensen Localization Image for FAM49A Gene COMPARTMENTS Subcellular localization image for FAM49A gene
Compartment Confidence
cytosol 2
cytoskeleton 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM49A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IDA --
genes like me logo Genes that share ontologies with FAM49A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for FAM49A Gene

Pathways for FAM49A Gene

SuperPathways for FAM49A Gene

No Data Available

Interacting Proteins for FAM49A Gene

Gene Ontology (GO) - Biological Process for FAM49A Gene


No data available for Pathways by source for FAM49A Gene

Transcripts for FAM49A Gene

Unigene Clusters for FAM49A Gene

Family with sequence similarity 49, member A:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM49A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM49A Gene

No ASD Table

Relevant External Links for FAM49A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM49A Gene

mRNA expression in normal human tissues for FAM49A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM49A Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (4.6), Brain - Anterior cingulate cortex (BA24) (4.3), and Whole Blood (4.1).

Protein differential expression in normal tissues for FAM49A Gene

This gene is overexpressed in Bone (43.7).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for FAM49A Gene

SOURCE GeneReport for Unigene cluster for FAM49A Gene Hs.467769

genes like me logo Genes that share expressions with FAM49A: view

Expression partners for FAM49A Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for FAM49A Gene

Orthologs for FAM49A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM49A Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM49A 35
  • 92.16 (n)
  • 100 (a)
FAM49A 36
  • 100 (a)
(Canis familiaris)
Mammalia FAM49A 35
  • 93.7 (n)
  • 100 (a)
FAM49A 36
  • 100 (a)
(Mus musculus)
Mammalia Fam49a 35
  • 90.3 (n)
  • 99.69 (a)
Fam49a 16
Fam49a 36
  • 100 (a)
(Pan troglodytes)
Mammalia FAM49A 35
  • 100 (n)
  • 100 (a)
FAM49A 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam49a 35
  • 91.02 (n)
  • 99.69 (a)
(Monodelphis domestica)
Mammalia FAM49A 36
  • 97 (a)
(Ornithorhynchus anatinus)
Mammalia FAM49A 36
  • 92 (a)
(Gallus gallus)
Aves FAM49A 35
  • 83.08 (n)
  • 96.59 (a)
FAM49A 36
  • 96 (a)
(Anolis carolinensis)
Reptilia FAM49A 36
  • 85 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam49a 35
  • 81.42 (n)
  • 95.36 (a)
Str.9897 35
(Danio rerio)
Actinopterygii sbcb866 35
znf395 35
  • 77.71 (n)
  • 86.38 (a)
znf395 36
  • 84 (a)
znf395 36
  • 86 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.12282 35
fruit fly
(Drosophila melanogaster)
Insecta CG32066 36
  • 52 (a)
(Caenorhabditis elegans)
Secernentea R07G3.8 35
  • 47.57 (n)
  • 38.41 (a)
R07G3.8 36
  • 35 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 56 (a)
Species with no ortholog for FAM49A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM49A Gene

Gene Tree for FAM49A (if available)
Gene Tree for FAM49A (if available)

Paralogs for FAM49A Gene

Paralogs for FAM49A Gene

(4) SIMAP similar genes for FAM49A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM49A: view

Variants for FAM49A Gene

Sequence variations from dbSNP and Humsavar for FAM49A Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs7552 -- 16,552,660(+) TATAG(A/G)TGTTG utr-variant-3-prime
rs15653 -- 16,550,242(+) CACCC(A/G)TAAGT utr-variant-3-prime
rs700423 -- 16,644,403(-) ACTAG(A/G)CACTG intron-variant
rs719433 -- 16,612,700(+) AGCTG(A/C)GTGAG intron-variant
rs751192 -- 16,615,202(+) CTGAA(C/T)GCAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM49A Gene

Variant ID Type Subtype PubMed ID
esv34115 CNV Loss 18971310
nsv506999 CNV Insertion 20534489
nsv2622 CNV Insertion 18451855
esv23923 CNV Loss 19812545

Relevant External Links for FAM49A Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM49A Gene

Disorders for FAM49A Gene

Relevant External Links for FAM49A

Genetic Association Database (GAD)

No disorders were found for FAM49A Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM49A Gene

Publications for FAM49A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4
  4. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PMID: 11256614) Simpson J.C. … Wiemann S. (EMBO Rep. 2000) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM49A Gene

Sources for FAM49A Gene

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