FAM47E Gene
protein-coding GIFtS: 35
GCID: GC04P077135
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family with sequence similarity 47, member E
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Aliases
for FAM47E gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 47, Member E1 2 | | FLJ429461 | | LOC1001295831 | | Protein FAM47E2 |
Export aliases for FAM47E gene to outside databasesPrevious GC identifers: GC04P077354 GC04P077391 GC04P077172 GC04P072924 |
Summaries
for FAM47E gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM47E gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM47E gene promoter:
AhR HOXA3 ATF-2 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM47E
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM47E |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q21.1 Ensembl cytogenetic band: 4q21.1 HGNC cytogenetic band: 4q21.1FAM47E Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P077135: view genomic region
(about GC identifiers)
Start:
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77,135,193 bp from pter |
End:
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77,232,282 bp from pter |
Size:
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97,090 bases |
Orientation:
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plus strand |
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Proteins
for FAM47E gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: FA47E_HUMAN, Q6ZV65 (See
protein sequence)Recommended Name: Protein FAM47E Size: 393 amino acids; 45662 Da
Secondary accessions: D6R8Y4Alternative splicing: 3 isoforms: Q6ZV65-3 Q6ZV65-2 Q6ZV65-1 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM47E: NX_Q6ZV65
FAM47E Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001130042.1 NP_001229865.1
ENSEMBL proteins: ENSP00000422262 ENSP00000422559 ENSP00000422067 ENSP00000424458 ENSP00000425528 ENSP00000409423 ENSP00000423044 ENSP00000340401
Human Recombinant Protein Products:
FAM47E Antibody Products:
Assay Products for FAM47E: |
Protein
Domains /
Families
for FAM47E gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6ZV65 UniProtKB/Swiss-Prot: FA47E_HUMAN, Q6ZV65Similarity: Belongs to the FAM47 family |
Function
for FAM47E gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM47E (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM47E
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM47E (NM_001136570) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM47E | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM47E |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM47E |
|
Pathways & Interactions
for FAM47E gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM47E
|
Drugs & Compounds
for FAM47E gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM47E
Search CenterWatch for drugs/clinical trials and news about FAM47E / FA47E
|
Transcripts
for FAM47E gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM47E gene (2 alternative transcripts): NM_001136570.2 NM_001242936.1 Unigene Cluster for FAM47E: Family with sequence similarity 47, member E Hs.720509 [show with all ESTs]Unigene Representative Sequence: NM_00124293911 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000510197(uc003hjv.3) ENST00000512895 ENST00000510328 ENST00000515604(uc003hjy.3 uc011cbv.2 uc011cbw.2)
ENST00000514365 ENST00000502320(uc003hjw.2 uc010ijf.2) ENST00000509377
ENST00000424749(uc003hjx.3) ENST00000514140 ENST00000511946 ENST00000339906
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM47E (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM47E
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM47E (NM_001136570) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM47E | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM47E |
Additional cDNA sequence: AK002155.1 AK124936.1 15 DOTS entries: DT.75101169 DT.121235234 DT.116065 DT.100755524 DT.101968082 DT.100755522 DT.108168 DT.100009065 DT.40128290 DT.91659128 DT.97766637 DT.100724266 DT.121235140 DT.121235194 DT.208081
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for FAM47E About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 |
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | - | | | |
ECgene alternative splicing isoforms for FAM47E
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Expression
for FAM47E gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM47E expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAATCTTCTC
About this image
See FAM47E Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM47E
SOURCE GeneReport for Unigene cluster: Hs.720509
SABiosciences Custom PCR Arrays for FAM47E
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM47E
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM47E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM47E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM47E | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM47E |
Orthologs
for FAM47E gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM47E gene from 3/12 species (see all 12) About this table
ENSEMBL Gene Tree for FAM47E (if available)
TreeFam Gene Tree for FAM47E (if available) |
Paralogs
for FAM47E gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM47E gene
- FAM47A2 FAM47C2 FAM47B2
1 SIMAP similar gene for FAM47E using alignment to 5 protein entries: FA47E_HUMAN (see all proteins):FAM47DP
FAM47E for paralogs About GeneDecksing
|
Genomic Variants
for FAM47E gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for FAM47E
1 CNV: 51461 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM47E |
|
Disorders
/ Diseases
for FAM47E gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM47E for disorders About GeneDecksing
1  disease for FAM47E: About MalaCardsparkinson's disease
Human Genome Epidemiology (HuGE) Navigator: FAM47E (1 document)
Export disorders for FAM47E gene to outside databases
|
Publications
for FAM47E gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM47E gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM47E) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Web-based genome-wide association study identifies tw o novel loci and a substantial genetic component for Parkinson's disease. (PubMed id 21738487)1 Do C.B....Eriksson N. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Genome-wide association study reveals genetic risk un derlying Parkinson's disease. (PubMed id 19915575)1 SimA^n-SA!nchez J....Gasser T. (2009)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
- The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
- Generation and analysis of 280,000 human expressed sequence tags. (PubMed id 8889549)1 Hillier L.D....Marra M. (1996)
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External Searches for FAM47E gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM47E gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM47E gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM47E gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM47E | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for FAM47E gene:
Search GeneIP for patents involving FAM47E
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM47E gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM47E | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM47E | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM47E | | | OriGene Protein Over-expression Lysate for FAM47E | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM47E | | OriGene 3'-UTR Clone for FAM47E | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM47E | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM47E | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM47E | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM47E | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM47E | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM47E | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM47E | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM47E |
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| | | | Search Tocris compounds for FAM47E |
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 | | | FAM47E Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM47E |
|  |  |  | | | | Search ThermoFisher Antibodies for FAM47E |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM47E |
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