FAM47C Gene
protein-coding GIFtS: 33
GCID: GC0XP037026
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Family With Sequence Similarity 47, Member C
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Aliases
for FAM47C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 47, Member C1 2 | | Putative Protein FAM47C2 |
Export aliases for FAM47C gene to outside databasesPrevious GC identifer: GC0XP036936 |
Summaries
for FAM47C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for FAM47C Gene:
This gene encodes a product belonging to a family of proteins with unknown function. The coding sequence of this familymember includes several tandemly repeated regions. (provided by RefSeq, Sep 2011)
GeneCards Summary for FAM47C Gene: 
FAM47C (family with sequence similarity 47, member C) is a protein-coding gene. An important paralog of this gene is FAM47A.
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Genomic Views
for FAM47C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.2 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM47C gene promoter:
POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 Evi-1 POU2F1 FOXO4 POU2F1b POU2F1a POU2F1c
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM47C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM47C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp21.1 Ensembl cytogenetic band: Xp21.1 HGNC cytogenetic band: Xp21.1FAM47C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP037026: view genomic region
(about GC identifiers)
Start:
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37,026,432 bp from pter |
End:
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37,029,739 bp from pter |
Size:
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3,308 bases |
Orientation:
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plus strand |
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Proteins
for FAM47C gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
|
UniProtKB/Swiss-Prot: FA47C_HUMAN, Q5HY64 (See
protein sequence)Recommended Name: Putative protein FAM47C Size: 1035 amino acids; 115338 Da
Sequence caution: Sequence=BAC86381.1; Type=Erroneous initiation;
Secondary accessions: Q6ZU46Explore the universe of human proteins at neXtProt for FAM47C: NX_Q5HY64
Explore proteomics data for FAM47C at MOPED
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q5HY64
FAM47C Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : About this image 
REFSEQ proteins: NP_001013758.1
ENSEMBL proteins: ENSP00000367913
Human Recombinant Protein Products for FAM47C:
FAM47C Antibody Products:
Assay Products for FAM47C: |
Protein
Domains /
Families
for FAM47C gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| 1 InterPro protein domain:Graphical View of Domain Structure for InterPro Entry Q5HY64 ProtoNet protein and cluster: Q5HY64 UniProtKB/Swiss-Prot: FA47C_HUMAN, Q5HY64Similarity: Belongs to the FAM47 family
FAM47C for domains About GeneDecksing
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Function
for FAM47C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
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Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM47C |
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Pathways & Interactions
for FAM47C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM47C
|
Drugs & Compounds
for FAM47C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
IUPHAR,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM47C (FA47C)
Search CenterWatch for drugs/clinical trials and news about FAM47C / FA47C
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Transcripts
for FAM47C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM47C gene: NM_001013736.2 Unigene Cluster for FAM47C: Family with sequence similarity 47, member C Hs.535216 [show with all ESTs]Unigene Representative Sequence: NM_0010137361 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000358047(uc004ddl.2)
Primer
Products: |  | Browse OriGene qPCR
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM47C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM47C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM47C |
Additional mRNA sequence: AK125992.1 1 DOTS entry: DT.40283264 6 AceView cDNA sequences: AW016180 AK125992 T19457 AI867768 AW172301 AI125523
GeneLoc Exon Structure
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Expression
for FAM47C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM47C expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image
See FAM47C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM47C
SOURCE GeneReport for Unigene cluster: Hs.535216
SABiosciences Custom PCR Arrays for FAM47C
Primer
Products: | | Browse OriGene qPCR
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM47C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM47C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM47C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM47C |
Orthologs
for FAM47C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for FAM47C gene from 2/8 species (see all 8) About this table
Species with no ortholog for FAM47C
ENSEMBL Gene Tree for FAM47C (if available)
TreeFam Gene Tree for FAM47C (if available) |
Paralogs
for FAM47C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM47C gene
- FAM47A2 ENSG000002724142 FAM47E2 FAM47B2
1 SIMAP similar gene for FAM47C using alignment to 1 protein entry: FA47C_HUMAN:FAM47A
FAM47C for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for FAM47C
PGOHUM00000246831 PGOHUM00000256836
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Genomic Variants
for FAM47C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FAM47C (37026432 - 37029739 bp)
Structural Variations
Database of Genomic Variants (DGV) variations for FAM47C: --
Locus Specific Mutation Databases (LSDB): FAM47C
| | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM47C |
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Disorders
/ Diseases
for FAM47C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM47C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM47C gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM47C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
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External Searches for FAM47C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM47C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing FAM47C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM47C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM47C | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM47C gene:
Search GeneIP for patents involving FAM47C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM47C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM47C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM47C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM47C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM47C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM47C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM47C |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM47C |
|  |  |  |  | | | | Search ThermoFisher Antibodies for FAM47C |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM47C |
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