Aliases for FAM47C Gene
Aliases for FAM47C Gene
External Ids for FAM47C Gene
- HGNC: 25301
- Entrez Gene: 442444
- Ensembl: ENSG00000198173
- UniProtKB: Q5HY64
Previous GeneCards Identifiers for FAM47C Gene
- GC0XP036936
Summaries for FAM47C Gene
-
This gene encodes a product belonging to a family of proteins with unknown function. The coding sequence of this family member includes several tandemly repeated regions. [provided by RefSeq, Sep 2011]
GeneCards Summary for FAM47C Gene
FAM47C (Family With Sequence Similarity 47 Member C) is a Protein Coding gene. An important paralog of this gene is FAM47B.
No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM47C Gene
Genomics for FAM47C Gene
Regulatory Elements for FAM47C Gene
Enhancers for FAM47C Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around FAM47C on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the FAM47C gene promoter:
Regulatory Element Products
Genomic Location for FAM47C Gene
- Chromosome:
- X
- Start:
- 37,008,359 bp from pter
- End:
- 37,011,666 bp from pter
- Size:
- 3,308 bases
- Orientation:
- Plus strand
Genomic View for FAM47C Gene
Genes around FAM47C on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp21.1 by Ensembl
- Xp21.1 by Entrez Gene
- Xp21.1 by HGNC
FAM47C Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FAM47C Gene
Proteins for FAM47C Gene
-
Protein details for FAM47C Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5HY64-FA47C_HUMAN
- Recommended name:
- Putative protein FAM47C
- Protein Accession:
- Q5HY64
- Q6ZU46
Protein attributes for FAM47C Gene
- Size:
- 1035 amino acids
- Molecular mass:
- 115338 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=BAC86381.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for FAM47C Gene
Post-translational modifications for FAM47C Gene
Other Protein References for FAM47C Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for FAM47C
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAM47C
- Search GeneTex for Proteins for FAM47C
Assay Products
No data available for DME Specific Peptides for FAM47C Gene
Domains & Families for FAM47C Gene
Suggested Antigen Peptide Sequences for FAM47C Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q5HY64- Family:
-
- Belongs to the FAM47 family.
No data available for Gene Families for FAM47C Gene
Function for FAM47C Gene
Phenotypes for FAM47C Gene
- GenomeRNAi human phenotypes for FAM47C:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM47C gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
- Search ViGene Biosciences for FAM47C
CRISPR Products
-
OriGene CRISPR knockouts for FAM47C
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM47C
- GenScript: Design CRISPR guide RNA sequences for FAM47C
miRNA for FAM47C Gene
- miRTarBase miRNAs that target FAM47C
miRNA Products
- Search ViGene Biosciences for FAM47C
Inhibitory RNA Products
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for FAM47C
- Browse OriGene Inhibitory RNA Products For FAM47C
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
Clone Products
- OriGene clones in human for FAM47C
- OriGene ORF clones in human,mouse for FAM47C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for FAM47C gene
-
ViGene Biosciences lentiviral particle packaged cDNA for FAM47C gene
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM47C Gene
Localization for FAM47C Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM47C Gene
More details on SuperPathways for FAM47CTranscripts for FAM47C Gene
mRNA/cDNA for FAM47C Gene
- (1) REFSEQ mRNAs :
- (1) Additional mRNA sequences :
- (6) Selected AceView cDNA sequences:
- (1) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for FAM47C Gene
- Family with sequence similarity 47, member C:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for FAM47C
-
Santa Cruz Biotechnology (SCBT) CRISPR for FAM47C
- GenScript: Design CRISPR guide RNA sequences for FAM47C
miRNA Products
- Search ViGene Biosciences for FAM47C
Inhibitory RNA Products
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for FAM47C
- Browse OriGene Inhibitory RNA Products For FAM47C
-
ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
Clone Products
- OriGene clones in human for FAM47C
- OriGene ORF clones in human,mouse for FAM47C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
Flow Cytometry Products
Expression for FAM47C Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for FAM47C Gene
This gene is overexpressed in Testis (x41.4).
This gene is overexpressed in Colon muscle (37.8) and Esophagus (31.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM47C Gene
SOURCE GeneReport for Unigene cluster for FAM47C Gene Hs.535216
Primer Products
No data available for mRNA Expression by UniProt/SwissProt for FAM47C Gene
Orthologs for FAM47C Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC473867 35 |
|
||
| FAM47C 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | -- 36 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 36 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | 4930402K13Rik 36 |
|
ManyToMany | |
| 4930480E11Rik 36 |
|
ManyToMany | |||
| Fam47c 36 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 36 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 36 |
|
ManyToMany | |
| -- 36 |
|
ManyToMany | |||
| zebrafish (Danio rerio) |
Actinopterygii | zgc:158260 36 |
|
ManyToMany | |
| zgc:158260 36 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.4199 36 |
|
OneToMany |
- Species with no ortholog for FAM47C:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- cow (Bos Taurus)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for FAM47C Gene
(1) SIMAP similar genes for FAM47C Gene using alignment to 1 proteins:
Pseudogenes.org Pseudogenes for FAM47C Gene
Variants for FAM47C Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1995914 | - | 37,011,181(+) | CCAGA(A/C/G)TGCAC | reference, missense | |
| rs1995915 | -- | 37,011,265(+) | GCTAA(A/G)AAGTG | reference, missense | |
| rs2731737 | -- | 37,008,424(-) | CCAGA(A/C/G/T)GCCGC | reference, missense | |
| rs28495724 | -- | 37,007,000(+) | CTGAT(A/G)TTATT | upstream-variant-2KB | |
| rs28592679 | -- | 37,011,705(+) | TTTAT(A/G)TGATT | downstream-variant-500B |
Residual Variation Intolerance Score:
99.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.57;
72.24% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for FAM47C Gene
- HapMap Linkage Disequilibrium report
- FAM47C
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM47C Gene
Disorders for FAM47C Gene
Relevant External Links for FAM47C
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- FAM47C
No disorders were found for FAM47C Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM47C Gene
Publications for FAM47C Gene
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 67
Products for FAM47C Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Browse OriGene Antibodies
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for FAM47C
- Origene siRNA, shRNA, and RNAi products in human, mouse, rat for FAM47C
- Browse OriGene Inhibitory RNA Products For FAM47C
- Browse OriGene qPCR primer pairs and template standards
- OriGene CRISPR knockouts for FAM47C
- OriGene clones in human for FAM47C
- OriGene ORF clones in human,mouse for FAM47C
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for FAM47C
- GenScript Custom Assay Services for FAM47C
- GenScript Custom overexpressing Cell Line Services for FAM47C
- GenScript: Design CRISPR guide RNA sequences for FAM47C
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for FAM47C
- ViGene Biosciences adenoviral particle packaged cDNA for FAM47C gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM47C gene
- ViGene Biosciences lentiviral particle packaged cDNA for FAM47C gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
- ViGene Biosciences ready-to-package AAV shRNAs for FAM47C gene
- Search ViGene Biosciences for FAM47C
- Search ViGene Biosciences for FAM47C
Sources for FAM47C Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon