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Aliases for FAM47C Gene

Aliases for FAM47C Gene

  • Family With Sequence Similarity 47 Member C 2 3 5
  • Family With Sequence Similarity 47, Member C 2

External Ids for FAM47C Gene

Previous GeneCards Identifiers for FAM47C Gene

  • GC0XP036936

Summaries for FAM47C Gene

Entrez Gene Summary for FAM47C Gene

  • This gene encodes a product belonging to a family of proteins with unknown function. The coding sequence of this family member includes several tandemly repeated regions. [provided by RefSeq, Sep 2011]

GeneCards Summary for FAM47C Gene

FAM47C (Family With Sequence Similarity 47 Member C) is a Protein Coding gene. An important paralog of this gene is FAM47A.

Additional gene information for FAM47C Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM47C Gene

Genomics for FAM47C Gene

Regulatory Elements for FAM47C Gene

Genomic Locations for FAM47C Gene

Genomic Locations for FAM47C Gene
3,308 bases
Plus strand

Genomic View for FAM47C Gene

Genes around FAM47C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM47C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM47C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM47C Gene

Proteins for FAM47C Gene

  • Protein details for FAM47C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative protein FAM47C
    Protein Accession:
    Secondary Accessions:
    • Q6ZU46

    Protein attributes for FAM47C Gene

    1035 amino acids
    Molecular mass:
    115338 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC86381.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for FAM47C Gene

Post-translational modifications for FAM47C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM47C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM47C Gene

Domains & Families for FAM47C Gene

Gene Families for FAM47C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM47C Gene


Suggested Antigen Peptide Sequences for FAM47C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM47 family.
  • Belongs to the FAM47 family.
genes like me logo Genes that share domains with FAM47C: view

Function for FAM47C Gene

genes like me logo Genes that share phenotypes with FAM47C: view

Animal Model Products

CRISPR Products

miRNA for FAM47C Gene

miRTarBase miRNAs that target FAM47C

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM47C Gene

Localization for FAM47C Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM47C gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM47C Gene

Pathways & Interactions for FAM47C Gene

SuperPathways for FAM47C Gene

No Data Available

Interacting Proteins for FAM47C Gene

Gene Ontology (GO) - Biological Process for FAM47C Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM47C Gene

Drugs & Compounds for FAM47C Gene

No Compound Related Data Available

Transcripts for FAM47C Gene

mRNA/cDNA for FAM47C Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM47C Gene

Family with sequence similarity 47, member C:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM47C Gene

No ASD Table

Relevant External Links for FAM47C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM47C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM47C Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM47C Gene

This gene is overexpressed in Testis (x41.4).

Protein differential expression in normal tissues from HIPED for FAM47C Gene

This gene is overexpressed in Colon muscle (37.8) and Esophagus (31.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM47C Gene

Protein tissue co-expression partners for FAM47C Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM47C Gene:


SOURCE GeneReport for Unigene cluster for FAM47C Gene:

genes like me logo Genes that share expression patterns with FAM47C: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM47C Gene

Orthologs for FAM47C Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM47C Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM47C 34
  • 92 (a)
LOC473867 33
  • 88.01 (n)
(Canis familiaris)
Mammalia -- 34
  • 46 (a)
(Mus musculus)
Mammalia Fam47c 34
  • 37 (a)
4930480E11Rik 34
  • 25 (a)
4930402K13Rik 34
  • 20 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 28 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 25 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 26 (a)
-- 34
  • 22 (a)
(Danio rerio)
Actinopterygii zgc:158260 34 34
  • 23 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4199 34
  • 20 (a)
Species where no ortholog for FAM47C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM47C Gene

Gene Tree for FAM47C (if available)
Gene Tree for FAM47C (if available)

Paralogs for FAM47C Gene

Paralogs for FAM47C Gene

(1) SIMAP similar genes for FAM47C Gene using alignment to 1 proteins: Pseudogenes for FAM47C Gene

genes like me logo Genes that share paralogs with FAM47C: view

Variants for FAM47C Gene

Sequence variations from dbSNP and Humsavar for FAM47C Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs112924019 -- 37,008,275(+) GGGCT(A/C/G)CGCAG upstream-variant-2KB
rs113171765 -- 37,012,123(+) GAAAG(A/G)ATAAT downstream-variant-500B
rs113759376 -- 37,009,155(+) GCCCA(C/G)AGCCT reference, missense
rs138169403 -- 37,009,941(+) ATCTC(C/T)GCCCA reference, missense
rs138293293 -- 37,010,575(+) GAGTC(A/G/T)CGTAT reference, missense

Variation tolerance for FAM47C Gene

Residual Variation Intolerance Score: 99.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.57; 72.24% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM47C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM47C Gene

Disorders for FAM47C Gene

Relevant External Links for FAM47C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM47C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM47C Gene

Publications for FAM47C Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4 60
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 4 60

Products for FAM47C Gene

Sources for FAM47C Gene

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