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Aliases for FAM47B Gene

Aliases for FAM47B Gene

  • Family With Sequence Similarity 47, Member B 2 3

External Ids for FAM47B Gene

Previous GeneCards Identifiers for FAM47B Gene

  • GC0XP034720
  • GC0XP032702

Summaries for FAM47B Gene

GeneCards Summary for FAM47B Gene

FAM47B (Family With Sequence Similarity 47, Member B) is a Protein Coding gene. An important paralog of this gene is FAM47C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM47B Gene

Genomics for FAM47B Gene

Regulatory Elements for FAM47B Gene

Genomic Location for FAM47B Gene

34,942,796 bp from pter
34,944,917 bp from pter
2,122 bases
Plus strand

Genomic View for FAM47B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM47B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM47B Gene

Proteins for FAM47B Gene

  • Protein details for FAM47B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM47B
    Protein Accession:
    Secondary Accessions:
    • Q5JQN5
    • Q6PIG3

    Protein attributes for FAM47B Gene

    645 amino acids
    Molecular mass:
    73945 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM47B Gene

Proteomics data for FAM47B Gene at MOPED

Post-translational modifications for FAM47B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM47B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM47B Gene

Domains & Families for FAM47B Gene

Protein Domains for FAM47B Gene


Suggested Antigen Peptide Sequences for FAM47B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM47 family.
  • Belongs to the FAM47 family.
genes like me logo Genes that share domains with FAM47B: view

No data available for Gene Families for FAM47B Gene

Function for FAM47B Gene

genes like me logo Genes that share phenotypes with FAM47B: view

Animal Model Products

CRISPR Products

miRNA for FAM47B Gene

miRTarBase miRNAs that target FAM47B

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM47B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM47B Gene

Localization for FAM47B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM47B Gene

Pathways & Interactions for FAM47B Gene

SuperPathways for FAM47B Gene

No Data Available

Interacting Proteins for FAM47B Gene

Gene Ontology (GO) - Biological Process for FAM47B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM47B Gene

Drugs & Compounds for FAM47B Gene

No Compound Related Data Available

Transcripts for FAM47B Gene

mRNA/cDNA for FAM47B Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(14) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM47B Gene

Family with sequence similarity 47, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM47B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM47B Gene

No ASD Table

Relevant External Links for FAM47B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM47B Gene

mRNA expression in normal human tissues for FAM47B Gene

mRNA differential expression in normal tissues according to GTEx for FAM47B Gene

This gene is overexpressed in Testis (x52.6).

SOURCE GeneReport for Unigene cluster for FAM47B Gene Hs.197801

genes like me logo Genes that share expression patterns with FAM47B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for FAM47B Gene

Orthologs for FAM47B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM47B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC473866 35
  • 84.92 (n)
  • 71.09 (a)
FAM47B 36
  • 95 (a)
(Canis familiaris)
Mammalia -- 36
  • 45 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 27 (a)
(Mus musculus)
Mammalia 4930402K13Rik 36
  • 21 (a)
4930480E11Rik 36
  • 25 (a)
Fam47c 36
  • 37 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 26 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 24 (a)
-- 36
  • 21 (a)
(Danio rerio)
Actinopterygii zgc:158260 36
  • 23 (a)
zgc:158260 36
  • 22 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4199 36
  • 20 (a)
Species with no ortholog for FAM47B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM47B Gene

Gene Tree for FAM47B (if available)
Gene Tree for FAM47B (if available)

Paralogs for FAM47B Gene

Paralogs for FAM47B Gene

(1) SIMAP similar genes for FAM47B Gene using alignment to 1 proteins: Pseudogenes for FAM47B Gene

genes like me logo Genes that share paralogs with FAM47B: view

Variants for FAM47B Gene

Sequence variations from dbSNP and Humsavar for FAM47B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3109502 -- 34,942,185(-) TTTTT(A/G)TAAAG upstream-variant-2KB
rs4829344 -- 34,940,878(+) TGTGT(A/G)TGTGT upstream-variant-2KB
rs4999833 -- 34,943,147(+) TTTCC(A/G)AGCTC missense, reference
rs5927343 -- 34,941,658(+) caaaa(A/C)aaaac upstream-variant-2KB
rs5973297 -- 34,940,888(+) TGTGT(G/T)TGTTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM47B Gene

Variant ID Type Subtype PubMed ID
esv2664433 CNV Deletion 23128226
nsv519107 CNV Gain 19592680
nsv527976 CNV Gain 19592680

Variation tolerance for FAM47B Gene

Residual Variation Intolerance Score: 96.01% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.27; 40.72% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM47B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM47B Gene

Disorders for FAM47B Gene

Relevant External Links for FAM47B

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with FAM47B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM47B Gene

Publications for FAM47B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 67
  3. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PMID: 17903301) Vasan R.S. … Benjamin E.J. (BMC Med. Genet. 2007) 67
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for FAM47B Gene

Sources for FAM47B Gene

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