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Aliases for FAM47A Gene

Aliases for FAM47A Gene

  • Family With Sequence Similarity 47 Member A 2 3 5
  • Family With Sequence Similarity 47, Member A 2
  • Similar To Hypothetical Protein FLJ35782 2

External Ids for FAM47A Gene

Previous GeneCards Identifiers for FAM47A Gene

  • GC0XM033907
  • GC0XM031885

Summaries for FAM47A Gene

GeneCards Summary for FAM47A Gene

FAM47A (Family With Sequence Similarity 47 Member A) is a Protein Coding gene. An important paralog of this gene is FAM47B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM47A Gene

Genomics for FAM47A Gene

Regulatory Elements for FAM47A Gene

Enhancers for FAM47A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM47A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM47A Gene

Chromosome:
X
Start:
34,129,752 bp from pter
End:
34,132,330 bp from pter
Size:
2,579 bases
Orientation:
Minus strand

Genomic View for FAM47A Gene

Genes around FAM47A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM47A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM47A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM47A Gene

Proteins for FAM47A Gene

  • Protein details for FAM47A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JRC9-FA47A_HUMAN
    Recommended name:
    Protein FAM47A
    Protein Accession:
    Q5JRC9
    Secondary Accessions:
    • A8K8I9
    • Q8TAA0

    Protein attributes for FAM47A Gene

    Size:
    791 amino acids
    Molecular mass:
    90592 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM47A Gene

Proteomics data for FAM47A Gene at MOPED

Post-translational modifications for FAM47A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM47A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM47A Gene

Domains & Families for FAM47A Gene

Protein Domains for FAM47A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM47A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5JRC9

UniProtKB/Swiss-Prot:

FA47A_HUMAN :
  • Belongs to the FAM47 family.
Family:
  • Belongs to the FAM47 family.
genes like me logo Genes that share domains with FAM47A: view

No data available for Gene Families for FAM47A Gene

Function for FAM47A Gene

Phenotypes for FAM47A Gene

GenomeRNAi human phenotypes for FAM47A:
genes like me logo Genes that share phenotypes with FAM47A: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM47A Gene

Localization for FAM47A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM47A Gene COMPARTMENTS Subcellular localization image for FAM47A gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM47A Gene

Pathways & Interactions for FAM47A Gene

SuperPathways for FAM47A Gene

No Data Available

Interacting Proteins for FAM47A Gene

Gene Ontology (GO) - Biological Process for FAM47A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM47A Gene

Drugs & Compounds for FAM47A Gene

No Compound Related Data Available

Transcripts for FAM47A Gene

mRNA/cDNA for FAM47A Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM47A Gene

Family with sequence similarity 47, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM47A Gene

No ASD Table

Relevant External Links for FAM47A Gene

GeneLoc Exon Structure for
FAM47A
ECgene alternative splicing isoforms for
FAM47A

Expression for FAM47A Gene

mRNA expression in normal human tissues for FAM47A Gene

mRNA differential expression in normal tissues according to GTEx for FAM47A Gene

This gene is overexpressed in Testis (x51.6).

Protein differential expression in normal tissues from HIPED for FAM47A Gene

This gene is overexpressed in Liver, secretome (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM47A Gene



SOURCE GeneReport for Unigene cluster for FAM47A Gene Hs.143268

genes like me logo Genes that share expression patterns with FAM47A: view

Protein tissue co-expression partners for FAM47A Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM47A Gene

Orthologs for FAM47A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM47A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM47A 35
  • 69.76 (n)
  • 52.46 (a)
mouse
(Mus musculus)
Mammalia Fam47c 35
  • 61.96 (n)
  • 44.8 (a)
Fam47c 16
4930402K13Rik 36
  • 21 (a)
ManyToMany
4930480E11Rik 36
  • 27 (a)
ManyToMany
Fam47c 36
  • 37 (a)
ManyToMany
chimpanzee
(Pan troglodytes)
Mammalia FAM47A 35
  • 99.13 (n)
  • 98.16 (a)
-- 36
  • 63 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Fam47a 35
  • 59.9 (n)
  • 44.01 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 47 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 28 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 27 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 28 (a)
ManyToMany
-- 36
  • 23 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii zgc:158260 36
  • 22 (a)
ManyToMany
zgc:158260 36
  • 21 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.4199 36
  • 20 (a)
OneToMany
Species with no ortholog for FAM47A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM47A Gene

ENSEMBL:
Gene Tree for FAM47A (if available)
TreeFam:
Gene Tree for FAM47A (if available)

Paralogs for FAM47A Gene

Paralogs for FAM47A Gene

(2) SIMAP similar genes for FAM47A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM47A: view

Variants for FAM47A Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for FAM47A Gene

FA47A_HUMAN-Q5JRC9
The repeat encompassing Pro-495 to Glu-507 may be polymorphic.

Sequence variations from dbSNP and Humsavar for FAM47A Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs17856750 - 34,132,131(+) CACAA(A/G)TACCC reference, missense
rs17856751 - 34,131,584(+) GGGAC(A/T)CTCCA reference, missense
rs1811716 - 34,131,150(-) TCCAC(G/T)CGGAG reference, missense
rs5971820 - 34,130,688(+) CGGAC(C/G)GAGAC reference, missense
rs747740472 -- 34,133,743(+) AAAAA(A/T)TTTAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM47A Gene

Variant ID Type Subtype PubMed ID
esv2752322 CNV Gain 17911159
nsv820274 CNV Gain 19587683

Variation tolerance for FAM47A Gene

Residual Variation Intolerance Score: 94.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.74; 33.07% of all genes are more intolerant (likely to be disease-causing)

No data available for Relevant External Links for FAM47A Gene

Disorders for FAM47A Gene

Relevant External Links for FAM47A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM47A

No disorders were found for FAM47A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM47A Gene

Publications for FAM47A Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Genome-wide association study of chronic periodontitis in a general German population. (PMID: 24024966) Teumer A. … Kocher T. (J. Clin. Periodontol. 2013) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS spectra. (PMID: 17924679) Yu L.R. … Veenstra T.D. (J. Proteome Res. 2007) 3

Products for FAM47A Gene

Sources for FAM47A Gene

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