Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FAM46C Gene

protein-coding   GIFtS: 50
GCID: GC01P118148

Family With Sequence Similarity 46, Member C

  See FAM46C-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Family With Sequence Similarity 46, Member C1 2
Protein FAM46C2

External Ids:    HGNC: 247121   Entrez Gene: 548552   Ensembl: ENSG000001835087   OMIM: 6139525   UniProtKB: Q5VWP23   

Export aliases for FAM46C gene to outside databases

Previous GC identifers: GC01P117860 GC01P117950 GC01P116005


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for FAM46C Gene:
FAM46C (family with sequence similarity 46, member C) is a protein-coding gene. Diseases associated with FAM46C include chromosome 1p deletion, and yellow fever. An important paralog of this gene is FAM46B.

UniProtKB/Swiss-Prot: FA46C_HUMAN, Q5VWP2
Function: Seems to enhance replication of some viruses, including yellow fever virus, in response to type I
interferon




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM46C gene promoter:
         USF1   AML1a   Nkx2-5   E4BP4   Nkx5-1   Tal-1beta   Evi-1   E47   USF-1   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM46C promoter sequence
   Search Chromatin IP Primers for FAM46C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM46C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p12   Ensembl cytogenetic band:  1p12   HGNC cytogenetic band: 1p12

FAM46C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM46C gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P118148:  view genomic region     (about GC identifiers)

Start:
118,148,556 bp from pter      End:
118,171,011 bp from pter
Size:
22,456 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FA46C_HUMAN, Q5VWP2 (See protein sequence)
Recommended Name: Protein FAM46C  
Size: 391 amino acids; 44944 Da
Secondary accessions: A3KMG2 Q8NE25 Q9NXK0

Explore the universe of human proteins at neXtProt for FAM46C: NX_Q5VWP2

Explore proteomics data for FAM46C at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys65, Lys234, Lys246, Lys264
  • Modification sites at PhosphoSitePlus

  • See FAM46C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060179.2  
    ENSEMBL proteins: 
     ENSP00000358458  

    FAM46C Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FAM46C
    OriGene Protein Over-expression Lysate for FAM46C
    OriGene MassSpec for FAM46C
    OriGene Custom Protein Services for FAM46C
    GenScript Custom Purified and Recombinant Proteins Services for FAM46C
    Novus Biologicals FAM46C Protein
    Novus Biologicals FAM46C Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM46C

     
    Search eBioscience for Proteins for FAM46C 

     
    antibodies-online proteins for FAM46C (3 products) 

     
    antibodies-online peptides for FAM46C

    FAM46C Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FAM46C
    Novus Biologicals FAM46C Antibodies
    Abcam antibodies for FAM46C
    Cloud-Clone Corp. Antibodies for FAM46C
    Search ThermoFisher Antibodies for FAM46C
    antibodies-online antibodies for FAM46C (15 products) 

    FAM46C Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FAM46C
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FAM46C
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FAM46C
    Cloud-Clone Corp. CLIAs for FAM46C
    Search eBioscience for ELISAs for FAM46C 
    antibodies-online kits for FAM46C (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR012937 DUF1693

    Graphical View of Domain Structure for InterPro Entry Q5VWP2

    ProtoNet protein and cluster: Q5VWP2

    1 Blocks protein domain: IPB012937 Protein of unknown function DUF1693

    UniProtKB/Swiss-Prot: FA46C_HUMAN, Q5VWP2
    Similarity: Belongs to the FAM46 family


    Find genes that share domains with FAM46C           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FA46C_HUMAN, Q5VWP2
    Function: Seems to enhance replication of some viruses, including yellow fever virus, in response to type I
    interferon
    Induction: By type I interferons

    Phenotypes:
         3 GenomeRNAi human phenotypes for FAM46C:

     Decreased viability of wild-ty  G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for FAM46C

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM46C:
    hsa-mir-98-5p (MIRT027756), hsa-mir-335-5p (MIRT018630)

    Block miRNA regulation of human, mouse, rat FAM46C using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM46C (see all 114):
    hsa-miR-576-3p hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-371-5p hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmidFAM46C 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM46C
    Predesigned siRNA for gene silencing in human, mouse, rat FAM46C

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FAM46C

    Clone
    Products:
         
    OriGene clones in human, mouse for FAM46C (see all 7)
    OriGene ORF clones in mouse, rat for FAM46C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM46C (NM_017709)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM46C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM46C

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAM46C
    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM46C 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM46C


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    cytosol1
    nucleus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM46C
    Interactions:

        Search GeneGlobe Interaction Network for FAM46C

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for FAM46C (Q5VWP22, 3 ENSP000003584584) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLK4O004442, 3, ENSP000002708614MINT-67059 I2D: score=5 STRING: ENSP00000270861
    AP2B1P630102, 3, ENSP000003144144MINT-68126 I2D: score=5 STRING: ENSP00000314414
    TRIP6Q156542, 3, ENSP000002004574MINT-66429 I2D: score=5 STRING: ENSP00000200457
    DAZAP2Q150382, 3, ENSP000004049684MINT-66199 I2D: score=4 STRING: ENSP00000404968
    CPSF7Q8N6843I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM46C (FA46C)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FAM46C gene: 
    NM_017709.3  

    Unigene Cluster for FAM46C:

    Family with sequence similarity 46, member C
    Hs.356216  [show with all ESTs]
    Unigene Representative Sequence: NM_017709
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000369448(uc001ehe.3)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM46C using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM46C (see all 114):
    hsa-miR-576-3p hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-371-5p hsa-miR-519a
    SwitchGear 3'UTR luciferase reporter plasmidFAM46C 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM46C
    Predesigned siRNA for gene silencing in human, mouse, rat FAM46C
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM46C (see all 7)
    OriGene ORF clones in mouse, rat for FAM46C
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM46C (NM_017709)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM46C
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM46C
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAM46C
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM46C
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat FAM46C
      QuantiTect SYBR Green Assays in human, mouse, rat FAM46C
      QuantiFast Probe-based Assays in human, mouse, rat FAM46C

    Additional mRNA sequence: 

    AK000209.1 AK091327.1 BC036516.2 BC131726.1 

    7 DOTS entries:

    DT.100749760  DT.114680  DT.121463791  DT.100738160  DT.121463775  DT.121463738  DT.121463826 

    Selected AceView cDNA sequences (see all 108):

    AL046017 BM727587 AA620782 AA933047 AI624555 NM_017709 H63792 AI207563 
    AW407254 AK091327 AA342944 AW514641 N76797 AW503624 AL046016 AI214292 
    BM729327 AI634701 AI828223 AW151275 CD300120 BM981557 H63752 CA314779 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FAM46C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGCAGCCT
    FAM46C Expression
    About this image


    FAM46C expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Testis (Reproductive System)    fully expand to see all 2 entries
             Testis Interstitium
     
     Placenta (Extraembryonic Tissues)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Mesenchymal Stem Cells (Uncategorized)    fully expand to see all 2 entries
             Placenta-derived mesenchymal stem cells (family)
     
     Peripheral Nervous System (Nervous System)
             Schwann Precursor Cells Peripheral Nerve Domain
     
     Fibroblasts
             Dermal Fibroblasts Dorsal Dermis
    FAM46C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM46C Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.356216
        Custom PCR Arrays for FAM46C
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FAM46C
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM46C
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat FAM46C
    QuantiTect SYBR Green Assays in human, mouse, rat FAM46C
    QuantiFast Probe-based Assays in human, mouse, rat FAM46C
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM46C

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for FAM46C gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam46c1 , 5 family with sequence similarity 46, member C1, 5 89.94(n)1
    95.91(a)1
      3 (43.71 cM)5
    746451  NM_001142952.11  NP_001136424.11 
     1004516285 
    chicken
    (Gallus gallus)
    Aves FAM46C1 family with sequence similarity 46, member C 78.8(n)
    89.49(a)
      426544  NM_001007972.1  NP_001007973.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fam46c1 family with sequence similarity 46, member C 77.58(n)
    83.38(a)
      100379867  XM_002943444.2  XP_002943490.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc661972 hypothetical protein MGC66197 73.9(n)   393479  BC048046.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG304971 CG30497 62.91(n)
    63.5(a)
      246653  NM_165556.2  NP_724601.1 
    worm
    (Caenorhabditis elegans)
    Secernentea pqn-441 pqn-44 52.3(n)
    48.28(a)
      172187  NM_059180.1  NP_491581.1 


    ENSEMBL Gene Tree for FAM46C (if available)
    TreeFam Gene Tree for FAM46C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FAM46C gene
    FAM46B2  FAM46D2  FAM46A2  
    4 SIMAP similar genes for FAM46C using alignment to 1 protein entry:     FA46C_HUMAN:
    FAM46A    XTP11    FAM46D    FAM46B

    Find genes that share paralogs with FAM46C           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FAM46C (see all 477)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs677499371,2
    C--116011862(+) GTCAA-/GTCA  
      
    /GTCAA
    AAGTG
    1 -- int11NA 2
    rs30509441,2
    C--116021654(-) cacac-/AC/A  
     CACACAC
    GACTT
    1 -- int10--------
    rs741126971,2
    C,F--118150466(+) GGGAAA/GCCTCT 1 -- int12Minor allele frequency- G:0.10WA 120
    rs1864879111,2
    --118150612(+) TATTCC/TCAATA 1 -- int10--------
    rs609639231,2
    C--118150716(+) AAAAA-/A/AA  
            
    CTCTG
    1 -- int11NA 2
    rs781926671,2
    C--118150716(+) AAAAA-/AA/CT 
            
    CTCTG
    1 -- int10--------
    rs2001554891,2
    --118150716(+) AAAAA-/ACTCTGCC 1 -- int10--------
    rs668220081,2
    C--118150717(+) AAAAA-/AA/CT 
            
    CTGCC
    1 -- int10--------
    rs2013541891,2
    --118150720(+) AACTC-/TGCCAGG 1 -- int10--------
    rs1463677311,2
    C--118150797(+) ATTAA-/ACCCC 
            
    CAGCC
    1 -- int10--------

    HapMap Linkage Disequilibrium report for FAM46C (118148556 - 118171011 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FAM46C:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv819506CNV Gain19587683
    nsv831170CNV Gain17160897

    Human Gene Mutation Database (HGMD): FAM46C
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM46C
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM46C

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613952    OMIM disorders: --

    2 diseases for FAM46C:    
    About MalaCards
    chromosome 1p deletion    yellow fever


    Find genes that share disorders with FAM46C           About GenesLikeMe

    Genetic Association Database (GAD): FAM46C

    Export disorders for FAM46C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FAM46C gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with FAM46C)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A diverse range of gene products are effectors of the type I interferon antiviral response. (PubMed id 21478870)1, 2 Schoggins J.W.... Rice C.M. (Nature 2011)
    2. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. Mapping of chromosome 1p deletions in myeloma identifies FAM46C at 1p12 and CDKN2C at 1p32.3 as being genes in regions associated with adverse survival. (PubMed id 21994415)1 Boyd K.D....Morgan G.J. (Clin. Cancer Res. 2011)
    8. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 54855 HGNC: 24712 AceView: FAM46C Ensembl:ENSG00000183508 euGenes: HUgn54855
    ECgene: FAM46C H-InvDB: FAM46C

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FAM46C Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FAM46C gene:
    Search GeneIP for patents involving FAM46C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for FAM46C  
     OriGene qPCR primer pairs and template standards for FAM46C   OriGene Protein Over-expression Lysate for FAM46C  
     OriGene MassSpec for FAM46C   OriGene clones in human, mouse for FAM46C  
     OriGene qSTAR qPCR primer pairs in human, mouse for FAM46C   OriGene Purified Protein for FAM46C  
     OriGene ORF clones in mouse, rat for FAM46C   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FAM46C   OriGene Custom Protein Services for FAM46C  

     
     
     Block miRNA regulation of human, mouse, rat FAM46C using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FAM46C
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM46C Predesigned siRNA for gene silencing in human, mouse, rat FAM46C
     QuantiFast Probe-based Assays in human, mouse, rat FAM46C QuantiTect SYBR Green Assays in human, mouse, rat FAM46C
     Custom PCR Arrays for FAM46C Search Chromatin IP Primers for FAM46C
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat FAM46C  Search GeneGlobe Interaction Network for FAM46C
     Regulatory tfbs in FAM46C promoter
     GenScript Custom Purified and Recombinant Proteins Services for FAM46C GenScript cDNA clones with any tag delivered in your preferred vector for FAM46C
     GenScript Custom Assay Services for FAM46C GenScript Custom overexpressing Cell Line Services for FAM46C
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FAM46C (FA46C)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FAM46C antibodies
     FAM46C proteins
     FAM46C lysates
     Antibodies for FAM46C
     See all of Abcam's Antibodies, Kits and Proteins for FAM46C
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FAM46C
     Antibodies for FAM46C
     ELISAs for FAM46C
     CLIAs for FAM46C



     Browse ESI BIO Cell Lines and PureStem Progenitors for FAM46C
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM46C
     SwitchGear 3'UTR luciferase reporter plasmids for FAM46C
     SwitchGear Promoter luciferase reporter plasmids for FAM46C
     Search ThermoFisher Antibodies for FAM46C
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM46C
     Browse compounds at ApexBio
     Search Addgene for plasmids for FAM46C
      Search eBioscience for proteins for FAM46C
      Search eBioscience for elisas for FAM46C
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for FAM46C
     antibodies-online antibodies for FAM46C (15 products)
     antibodies-online kits for FAM46C (8 products)
     antibodies-online peptides for FAM46C
     antibodies-online proteins for FAM46C (3 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FAM46C gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4