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Aliases for FAM45B Gene

Aliases for FAM45B Gene

  • Family With Sequence Similarity 45, Member B (Pseudogene) 2
  • Family With Sequence Similarity 45, Member A Pseudogene 3
  • Family With Sequence Similarity 45, Member B 2
  • HT011 3

External Ids for FAM45B Gene

Previous GeneCards Identifiers for FAM45B Gene

  • GC0XP129354
  • GC0XP129457
  • GC0XP129628
  • GC0XP119024

Summaries for FAM45B Gene

GeneCards Summary for FAM45B Gene

FAM45B (Family With Sequence Similarity 45, Member B (Pseudogene)) is a Pseudogene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM45B Gene

Genomics for FAM45B Gene

Regulatory Elements for FAM45B Gene

Genomic Location for FAM45B Gene

Chromosome:
X
Start:
130,494,941 bp from pter
End:
130,497,448 bp from pter
Size:
2,508 bases
Orientation:
Plus strand

Genomic View for FAM45B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for FAM45B Gene

Proteins for FAM45B Gene

  • Protein details for FAM45B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6NSW5-FA45B_HUMAN
    Recommended name:
    Protein FAM45B
    Protein Accession:
    Q6NSW5
    Secondary Accessions:
    • Q5H9G7
    • Q9NZ36

    Protein attributes for FAM45B Gene

    Size:
    357 amino acids
    Molecular mass:
    40514 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF67650.1; Type=Frameshift; Positions=353; Evidence={ECO:0000305};

neXtProt entry for FAM45B Gene

Proteomics data for FAM45B Gene at MOPED

Post-translational modifications for FAM45B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM45B Gene

Domains & Families for FAM45B Gene

Protein Domains for FAM45B Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM45B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6NSW5

UniProtKB/Swiss-Prot:

FA45B_HUMAN :
  • Belongs to the FAM45 family.
Family:
  • Belongs to the FAM45 family.
genes like me logo Genes that share domains with FAM45B: view

No data available for Gene Families for FAM45B Gene

Function for FAM45B Gene

Phenotypes for FAM45B Gene

GenomeRNAi human phenotypes for FAM45B:
genes like me logo Genes that share phenotypes with FAM45B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM45B Gene

Localization for FAM45B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for FAM45B Gene

Pathways & Interactions for FAM45B Gene

SuperPathways for FAM45B Gene

No Data Available

Interacting Proteins for FAM45B Gene

Gene Ontology (GO) - Biological Process for FAM45B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM45B Gene

Drugs & Compounds for FAM45B Gene

No Compound Related Data Available

Transcripts for FAM45B Gene

mRNA/cDNA for FAM45B Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(61) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM45B Gene

Family with sequence similarity 45, member A pseudogene:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM45B Gene

No ASD Table

Relevant External Links for FAM45B Gene

GeneLoc Exon Structure for
FAM45B
ECgene alternative splicing isoforms for
FAM45B

Expression for FAM45B Gene

mRNA expression in normal human tissues for FAM45B Gene

Protein differential expression in normal tissues from HIPED for FAM45B Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM45B Gene



SOURCE GeneReport for Unigene cluster for FAM45B Gene Hs.567120

genes like me logo Genes that share expression patterns with FAM45B: view

Protein tissue co-expression partners for FAM45B Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM45B Gene

Orthologs for FAM45B Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM45B Gene

Organism Taxonomy Gene Similarity Type Details
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2957 35
Species with no ortholog for FAM45B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM45B Gene

ENSEMBL:
Gene Tree for FAM45B (if available)
TreeFam:
Gene Tree for FAM45B (if available)

Paralogs for FAM45B Gene

(1) SIMAP similar genes for FAM45B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM45B: view

No data available for Paralogs for FAM45B Gene

Variants for FAM45B Gene

Sequence variations from dbSNP and Humsavar for FAM45B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2232308 -- 130,494,106(+) TACTT(C/T)TGGGC upstream-variant-2KB
rs2232309 -- 130,494,173(+) TCCTC(A/T)CTAGG upstream-variant-2KB
rs2232310 -- 130,494,545(+) GTGAG(A/C)ATTAC upstream-variant-2KB
rs778254003 -- 130,496,265(+) CTGAT(-/AGAA)AGCCC nc-transcript-variant
rs778143147 -- 130,493,938(+) GCCTA(C/T)TAAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM45B Gene

Variant ID Type Subtype PubMed ID
esv23185 CNV Gain 19812545

Relevant External Links for FAM45B Gene

HapMap Linkage Disequilibrium report
FAM45B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FAM45B Gene

Disorders for FAM45B Gene

Relevant External Links for FAM45B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM45B
genes like me logo Genes that share disorders with FAM45B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM45B Gene

Publications for FAM45B Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PMID: 10931946) Hu R.-M. … Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000) 67

Products for FAM45B Gene

Sources for FAM45B Gene

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