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Aliases for FAM45A Gene

Aliases for FAM45A Gene

  • Family With Sequence Similarity 45, Member A 2 3

External Ids for FAM45A Gene

Previous GeneCards Identifiers for FAM45A Gene

  • GC10P120853
  • GC10P114500

Summaries for FAM45A Gene

GeneCards Summary for FAM45A Gene

FAM45A (Family With Sequence Similarity 45, Member A) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM45A Gene

Genomics for FAM45A Gene

Regulatory Elements for FAM45A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM45A Gene

Start:
119,104,065 bp from pter
End:
119,137,984 bp from pter
Size:
33,920 bases
Orientation:
Plus strand

Genomic View for FAM45A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM45A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM45A Gene

Proteins for FAM45A Gene

  • Protein details for FAM45A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TCE6-FA45A_HUMAN
    Recommended name:
    Protein FAM45A
    Protein Accession:
    Q8TCE6
    Secondary Accessions:
    • B1AMV6
    • B4DDC3
    • D3DRC8
    • Q9NXW4

    Protein attributes for FAM45A Gene

    Size:
    357 amino acids
    Molecular mass:
    40513 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM45A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM45A Gene

Proteomics data for FAM45A Gene at MOPED

Post-translational modifications for FAM45A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM45A Gene

No data available for DME Specific Peptides for FAM45A Gene

Domains for FAM45A Gene

Protein Domains for FAM45A Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q8TCE6

UniProtKB/Swiss-Prot:

FA45A_HUMAN :
  • Q8TCE6
Family:
  • Belongs to the FAM45 family.
genes like me logo Genes that share domains with FAM45A: view

No data available for Gene Families for FAM45A Gene

Function for FAM45A Gene

Animal Model Products

CRISPR Products

miRNA for FAM45A Gene

miRTarBase miRNAs that target FAM45A

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM45A

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM45A Gene

Localization for FAM45A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM45A Gene COMPARTMENTS Subcellular localization image for FAM45A gene
Compartment Confidence
cytosol 2
mitochondrion 2
cytoskeleton 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM45A Gene

Pathways for FAM45A Gene

SuperPathways for FAM45A Gene

No Data Available

Interacting Proteins for FAM45A Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000354688%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000261733%0d%0a
Selected Interacting proteins: ENSP00000354688 Q8TCE6-FA45A_HUMAN for FAM45A Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM45A Gene

None

No data available for Pathways by source for FAM45A Gene

Transcripts for FAM45A Gene

Unigene Clusters for FAM45A Gene

Family with sequence similarity 45, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM45A

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for FAM45A

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM45A Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c · 8d ^ 9a ·
SP1: - - - - - - - - - - - -
SP2:
SP3: - - - - - - - - - - -
SP4: - - - - - - - - - - - -
SP5: - - - - - - - - - - - - - -
SP6: - - - - - - - -
SP7: - - - - - - - - - - - - -
SP8: - - - - - -
SP9: - - - - - - - - -
SP10: - - - - - - - - - - -
SP11: - - - - - - - - - - - - - - -
SP12: - - - - - - - -
SP13: - - - - - - - - -
SP14: - - - - - - -
SP15: - - - - - - - - -
SP16: - -
SP17: - - - - -
SP18: - - - - - - - - - -
SP19: - - - - - -
SP20: - - - - - - -
SP21: - - - - - -
SP22: - -
SP23: - - - -
SP24: - - -
SP25:

ExUns: 9b · 9c · 9d ^ 10a · 10b ^ 11a · 11b ^ 12 ^ 13
SP1:
SP2:
SP3:
SP4: - - -
SP5:
SP6:
SP7: - - -
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:

Relevant External Links for FAM45A Gene

GeneLoc Exon Structure for
FAM45A
ECgene alternative splicing isoforms for
FAM45A

Expression for FAM45A Gene

mRNA expression in normal human tissues for FAM45A Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM45A Gene

SOURCE GeneReport for Unigene cluster for FAM45A Gene Hs.434241

genes like me logo Genes that share expressions with FAM45A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM45A Gene

Orthologs for FAM45A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM45A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM45A 35
  • 99.51 (n)
  • 99.41 (a)
FAM45A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM45A 35
  • 91.69 (n)
  • 94.96 (a)
FAM45A 36
  • 95 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM45A 35
  • 90.85 (n)
  • 92.44 (a)
FAM45A 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam45a 35
  • 88.42 (n)
  • 90.48 (a)
Fam45a 16
Fam45a 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM45A 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM45A 36
  • 80 (a)
OneToOne
chicken
(Gallus gallus)
Aves FAM45A 35
  • 78.76 (n)
  • 83.71 (a)
FAM45A 36
  • 83 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM45A 36
  • 83 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii fam45a 35
  • 68.96 (n)
  • 70.49 (a)
fam45a 36
  • 69 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 41 (a)
OneToOne
Species with no ortholog for FAM45A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM45A Gene

ENSEMBL:
Gene Tree for FAM45A (if available)
TreeFam:
Gene Tree for FAM45A (if available)

Paralogs for FAM45A Gene

Selected SIMAP similar genes for FAM45A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with FAM45A: view

No data available for Paralogs for FAM45A Gene

Variants for FAM45A Gene

Sequence variations from dbSNP and Humsavar for FAM45A Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type MAF
rs907213 -- 119,133,417(-) AGGCA(C/T)CAGGT intron-variant
rs915272 -- 119,133,030(+) AATCA(C/T)GCAGT intron-variant
rs1048713 -- 119,137,639(+) ATTGA(C/T)TGTAA utr-variant-3-prime
rs1107702 -- 119,133,610(-) TCAAC(A/C)CCTTC intron-variant
rs1247798 -- 119,126,635(+) aattt(C/T)tgtat intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM45A Gene

Variant ID Type Subtype PubMed ID
esv23185 CNV Gain 19812545

Relevant External Links for FAM45A Gene

HapMap Linkage Disequilibrium report
FAM45A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM45A Gene

Disorders for FAM45A Gene

No disorders were found for FAM45A Gene.

No data available for UniProtKB/Swiss-Prot for FAM45A Gene

Publications for FAM45A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  4. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM45A Gene

Sources for FAM45A Gene

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