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Aliases for FAM43B Gene

Aliases for FAM43B Gene

  • Family With Sequence Similarity 43, Member B 2 3

External Ids for FAM43B Gene

Previous GeneCards Identifiers for FAM43B Gene

  • GC01P020624
  • GC01P020751
  • GC01P020878
  • GC01P019124

Summaries for FAM43B Gene

GeneCards Summary for FAM43B Gene

FAM43B (Family With Sequence Similarity 43, Member B) is a Protein Coding gene. An important paralog of this gene is FAM43A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM43B Gene

Genomics for FAM43B Gene

Regulatory Elements for FAM43B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM43B Gene

20,552,439 bp from pter
20,555,020 bp from pter
2,582 bases
Plus strand

Genomic View for FAM43B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM43B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM43B Gene

Proteins for FAM43B Gene

  • Protein details for FAM43B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM43B
    Protein Accession:
    Secondary Accessions:
    • A5PKT8
    • A5PL01

    Protein attributes for FAM43B Gene

    329 amino acids
    Molecular mass:
    36776 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM43B Gene

Proteomics data for FAM43B Gene at MOPED

Post-translational modifications for FAM43B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM43B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM43B Gene

Domains for FAM43B Gene

Protein Domains for FAM43B Gene


Suggested Antigen Peptide Sequences for FAM43B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM43 family.
  • Belongs to the FAM43 family.
genes like me logo Genes that share domains with FAM43B: view

No data available for Gene Families for FAM43B Gene

Function for FAM43B Gene

Gene Ontology (GO) - Molecular Function for FAM43B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with FAM43B: view

Animal Model Products

miRNA for FAM43B Gene

miRTarBase miRNAs that target FAM43B

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM43B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM43B Gene

Localization for FAM43B Gene

Subcellular locations from

Jensen Localization Image for FAM43B Gene COMPARTMENTS Subcellular localization image for FAM43B gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM43B Gene

Pathways for FAM43B Gene

SuperPathways for FAM43B Gene

No Data Available

Interacting Proteins for FAM43B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000331397 for FAM43B Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for FAM43B Gene


No data available for Pathways by source for FAM43B Gene

Transcripts for FAM43B Gene

mRNA/cDNA for FAM43B Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM43B Gene

Family with sequence similarity 43, member B:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM43B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM43B Gene

No ASD Table

Relevant External Links for FAM43B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM43B Gene

mRNA expression in normal human tissues for FAM43B Gene

mRNA differential expression in normal tissues according to GTEx for FAM43B Gene

This gene is overexpressed in Adrenal Gland (7.2).

Protein differential expression in normal tissues for FAM43B Gene

This gene is overexpressed in Adipocyte (68.5).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM43B Gene

SOURCE GeneReport for Unigene cluster for FAM43B Gene Hs.429179

genes like me logo Genes that share expressions with FAM43B: view

Expression partners for FAM43B Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM43B Gene

Orthologs for FAM43B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM43B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM43B 35
  • 94.6 (n)
  • 93.46 (a)
FAM43B 36
  • 92 (a)
(Mus musculus)
Mammalia Fam43b 35
  • 91.77 (n)
  • 92.68 (a)
Fam43b 16
Fam43b 36
  • 92 (a)
(Pan troglodytes)
Mammalia FAM43B 35
  • 99.8 (n)
  • 99.7 (a)
FAM43B 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam43b 35
  • 92.07 (n)
  • 94.82 (a)
(Monodelphis domestica)
Mammalia FAM43B 36
  • 90 (a)
(Ornithorhynchus anatinus)
Mammalia FAM43B 36
  • 77 (a)
(Gallus gallus)
Aves LOC100858896 35
  • 72.16 (n)
  • 71.58 (a)
FAM43B 36
  • 69 (a)
(Danio rerio)
Actinopterygii fam43b 35
  • 58.97 (n)
  • 57.24 (a)
fam43b 36
  • 54 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8312 36
  • 12 (a)
(Caenorhabditis elegans)
Secernentea F52D10.2 36
  • 21 (a)
Species with no ortholog for FAM43B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for FAM43B Gene

Gene Tree for FAM43B (if available)
Gene Tree for FAM43B (if available)

Paralogs for FAM43B Gene

Paralogs for FAM43B Gene

(1) SIMAP similar genes for FAM43B Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM43B: view

Variants for FAM43B Gene

Sequence variations from dbSNP and Humsavar for FAM43B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs374561678 -- 20,551,305(+) TGGCC(A/G)AGATA upstream-variant-2KB
rs374052462 -- 20,550,864(+) AGTCC(C/T)TTCCA upstream-variant-2KB
rs373738446 -- 20,553,069(+) TCGCT(G/T)CTCTC reference, synonymous-codon
rs373700309 -- 20,553,277(+) CTCGC(C/T)GCGGG missense, reference
rs373477525 -- 20,554,452(+) GCCGG(C/G)GGTGG utr-variant-3-prime

Relevant External Links for FAM43B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for FAM43B Gene

Disorders for FAM43B Gene

Relevant External Links for FAM43B

Genetic Association Database (GAD)

No disorders were found for FAM43B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM43B Gene

Publications for FAM43B Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  3. Expression of a novel gene FAM43B repressing cell proliferation is regulated by DNA methylation in hepatocellular carcinoma cell lines. (PMID: 21461611) Xu X. … Han Z.G. (Mol. Cell. Biochem. 2011) 2 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM43B Gene

Sources for FAM43B Gene

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