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FAM3A Gene

protein-coding   GIFtS: 54
GCID: GC0XM153734

Family With Sequence Similarity 3, Member A

  Search for FAM3A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 3, Member A1 2     DXS560S2
Cytokine-Like Protein 2-192 3     XAP-72
2.192 3     Protein FAM3A2
DLD2     2-193

External Ids:    HGNC: 137491   Entrez Gene: 603432   Ensembl: ENSG000000718897   OMIM: 3004925   UniProtKB: P981733   

Export aliases for FAM3A gene to outside databases

Previous GC identifers: GC0XM147792 GC0XM150115 GC0XM151320 GC0XM152202 GC0XM153298 GC0XM153387 GC0XM142310


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FAM3A Gene:
This gene encodes a cytokine-like protein. The expression of this gene may be regulated by peroxisome
proliferator-activated receptor gamma, and the encoded protein may be involved in the regulation of glucose and
lipid metabolism. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Aug 2013)

GeneCards Summary for FAM3A Gene:
FAM3A (family with sequence similarity 3, member A) is a protein-coding gene. An important paralog of this gene is FAM3D.

UniProtKB/Swiss-Prot: FAM3A_HUMAN, P98173
Function: May act as a defensin against invading fungal microorganisms




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011681.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM3A gene promoter:
         STAT1   p53   STAT1beta   RelA   HNF-4alpha2   STAT1alpha   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM3A promoter sequence
   Search Chromatin IP Primers for FAM3A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM3A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

FAM3A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM3A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM153734:  view genomic region     (about GC identifiers)

Start:
153,733,323 bp from pter      End:
153,744,566 bp from pter
Size:
11,244 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: FAM3A_HUMAN, P98173 (See protein sequence)
Recommended Name: Protein FAM3A precursor  
Size: 230 amino acids; 25152 Da
Secondary accessions: A6QRH6 B2RBI7 B4DFI8 D3DWX4 Q5HY76 Q96H51
Alternative splicing: 3 isoforms:  P98173-1   P98173-2   P98173-3   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for FAM3A: NX_P98173

Explore proteomics data for FAM3A at MOPED


See FAM3A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (6 alternative transcripts): 
NP_001164603.1  NP_001164604.1  NP_001164605.1  NP_001269240.1  NP_001269241.1  NP_068578.2  

ENSEMBL proteins: 
 ENSP00000352955   ENSP00000358657   ENSP00000416146   ENSP00000320521   ENSP00000393086  
 ENSP00000358655   ENSP00000377202   ENSP00000404171   ENSP00000415843   ENSP00000396845  
 ENSP00000401367   ENSP00000407870   ENSP00000397396   ENSP00000406340   ENSP00000408973  
 ENSP00000392624   ENSP00000396243  

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Cloud-Clone Corp. Proteins for FAM3A

 
Search eBioscience for Proteins for FAM3A 

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LSBio Antibodies in human, mouse, rat for FAM3A

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR026101 FAM3

Graphical View of Domain Structure for InterPro Entry P98173

ProtoNet protein and cluster: P98173

UniProtKB/Swiss-Prot: FAM3A_HUMAN, P98173
Similarity: Belongs to the FAM3 family


Find genes that share domains with FAM3A           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: FAM3A_HUMAN, P98173
Function: May act as a defensin against invading fungal microorganisms

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
Find genes that share ontologies with FAM3A           About GenesLikeMe


Phenotypes:
     1 GenomeRNAi human phenotype for FAM3A:
 Increased gamma-H2AX phosphory 

     1 MGI phenotypic allele for Fam3a (no phenotypes)

Find genes that share phenotypes with FAM3A           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM3A
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM3A

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM3A
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM3A

miRNA
Products:
    
miRTarBase miRNAs that target FAM3A:
hsa-mir-92a-3p (MIRT049720), hsa-mir-18a-3p (MIRT040766), hsa-mir-26b-5p (MIRT029626)

Block miRNA regulation of human, mouse, rat FAM3A using miScript Target Protectors
6 qRT-PCR Assays for microRNAs that regulate FAM3A:
hsa-miR-4261 hsa-miR-1184 hsa-miR-4288 hsa-miR-632 hsa-miR-1299 hsa-miR-3943
SwitchGear 3'UTR luciferase reporter plasmidFAM3A 3' UTR sequence
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for FAM3A
Predesigned siRNA for gene silencing in human, mouse, rat FAM3A

Gene Editing
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GenScript: all cDNA clones in your preferred vector (see all 4): FAM3A (NM_021806)
Sino Biological Human cDNA Clone for FAM3A
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM3A
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM3A

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM3A


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
FAM3A_HUMAN, P98173: Secreted (Potential)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular3
golgi apparatus1
plasma membrane1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005575cellular_component ND--
GO:0005576extracellular region IEA--

Find genes that share ontologies with FAM3A           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM3A
Interactions:

    Search GeneGlobe Interaction Network for FAM3A

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for FAM3A (P981733 ENSP000003529554) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
CREB3O438893I2D: score=1 
PACRGLENSP000002952904STRING: ENSP00000295290
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008150biological_process ND--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for FAM3A



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for FAM3A gene (6 alternative transcripts): 
NM_001171132.2  NM_001171133.2  NM_001171134.2  NM_001282311.1  NM_001282312.1  NM_021806.3  

Unigene Cluster for FAM3A:

Family with sequence similarity 3, member A
Hs.289108  [show with all ESTs]
Unigene Representative Sequence: NR_033237
Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
ENST00000359889 ENST00000369643 ENST00000447601 ENST00000322269 ENST00000469041
ENST00000419205 ENST00000369641 ENST00000393572 ENST00000475657 ENST00000449971
ENST00000416319 ENST00000426266 ENST00000440318 ENST00000457212 ENST00000412894
ENST00000421517 ENST00000497506 ENST00000442929
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat FAM3A using miScript Target Protectors
6 qRT-PCR Assays for microRNAs that regulate FAM3A:
hsa-miR-4261 hsa-miR-1184 hsa-miR-4288 hsa-miR-632 hsa-miR-1299 hsa-miR-3943
SwitchGear 3'UTR luciferase reporter plasmidFAM3A 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for FAM3A
Predesigned siRNA for gene silencing in human, mouse, rat FAM3A
Clone
Products:
     
OriGene clones in human, mouse for FAM3A (see all 19)
OriGene ORF clones in mouse, rat for FAM3A
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 4): FAM3A (NM_021806)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM3A
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM3A
Primer
Products:
    
OriGene qPCR primer pairs and template standards for FAM3A
OriGene qSTAR qPCR primer pairs in human, mouse for FAM3A
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM3A
  QuantiTect SYBR Green Assays in human, mouse, rat FAM3A
  QuantiFast Probe-based Assays in human, mouse, rat FAM3A

Additional mRNA sequence: 

AK024601.1 AK057945.1 AK294116.1 AK314682.1 BC008912.2 NR_033237.1 X74610.1 X87193.1 

Selected DOTS entries (see all 25):

DT.454876  DT.100029830  DT.95097567  DT.100812721  DT.121293809  DT.95236851  DT.100812727  DT.91754049 
DT.100812732  DT.100716669  DT.100812742  DT.91754047  DT.121294724  DT.91754046  DT.95309207  DT.100029829 
DT.100669625  DT.100812737  DT.40106365  DT.40310720  DT.101972691  DT.121294104  DT.40223786  DT.75135543 

Selected AceView cDNA sequences (see all 314):

BU859705 BU735081 AL048549 CB268817 BM450112 AU105865 AI672209 BU539314 
AI268794 BM472817 AW178369 BU168380 BM980586 BM681603 BM712489 BQ962278 
BM924611 BM680415 BU556849 AA992496 R87246 BM676010 AA448649 AA322095 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM3A (see all 8)    About this scheme

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a · 10b ^ 11a · 11b · 11c
SP1:                                                  -                 -     -                       -                                                         
SP2:                                            -     -     -           -     -                       -                                                         
SP3:                                                  -     -           -                             -                                                         
SP4:                                                  -                 -     -                       -     -                                                   
SP5:                                                                                                                                                            


ECgene alternative splicing isoforms for FAM3A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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FAM3A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGCCTGACTG
FAM3A Expression
About this image


FAM3A expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 
 Heart (Cardiovascular System)    fully expand to see all 2 entries
         Atrioventricular Canal Cells Atrioventricular Canal
         Outflow Tract
FAM3A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

FAM3A Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.289108

UniProtKB/Swiss-Prot: FAM3A_HUMAN, P98173
Tissue specificity: In similar amounts in testis, pancreas, adrenal, placenta, brain, fetal brain, liver, kidney,
skeletal muscle and heart

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QuantiTect SYBR Green Assays in human, mouse, rat FAM3A
QuantiFast Probe-based Assays in human, mouse, rat FAM3A
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM3A

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for FAM3A gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Fam3a1 , 5 family with sequence similarity 3, member A1, 5 86.32(n)1
91.27(a)1
  X (38.00 cM)5
662941  NM_025473.31  NP_079749.11 
 743847195 
lizard
(Anolis carolinensis)
Reptilia FAM3A6
family with sequence similarity 3, member A
80(a)
1 ↔ 1
1(204807381-204828346)
African clawed frog
(Xenopus laevis)
Amphibia fam3a-prov2 family with sequence similarity 3, member A 75.06(n)    BC043826.1 
zebrafish
(Danio rerio)
Actinopterygii zgc733502 hypothetical protein MGC73350 74.98(n)   393773  BC059665.1 
worm
(Caenorhabditis elegans)
Secernentea Y73B3A.36
M70.46
Protein M70.4 (M70.4) mRNA, complete cds
7(a)
7(a)
many ↔ many
many ↔ many
X(84043-93664) WBGene00022205
IV(2253004-2263660) WBGene00019786


ENSEMBL Gene Tree for FAM3A (if available)
TreeFam Gene Tree for FAM3A (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for FAM3A gene
FAM3D2  FAM3C2  FAM3B2  
Selected SIMAP similar genes for FAM3A using alignment to 11 protein entries:     FAM3A_HUMAN (see all proteins) (see all similar genes):
GRIK2    MEFV    SUN3    ARV1    ATL2    COL24A1
COX7A2    EDRF1    IFT122    LAMA5    POU4F3    UTY
HKR1    POMZP3    THEMIS    ZNF480    BUB1B    C12orf23

Find genes that share paralogs with FAM3A           About GenesLikeMe


1 Pseudogenes.org Pseudogene for FAM3A
PGOHUM00000250065


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for FAM3A (see all 264)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr X posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1470597671,2
C--153601246(+) CCCAGA/GCTGGA 5 -- ds50010--------
rs1812055491,2
--153601317(+) TGCCTC/TGGCCT 5 -- ds50010--------
rs1861832851,2
--153601350(+) CGCCCA/GCCACC 5 -- ds50010--------
rs1913744101,2
--153601357(+) CACCAC/TGCCTG 5 -- ds50010--------
rs1836188801,2
--153601387(+) GAGACA/GGGAGT 5 -- ds50010--------
rs1885866141,2
--153601395(+) AGTCAC/TGCTCT 5 -- ds50010--------
rs1911821841,2
C--153601457(+) CCTCCC/TGGGTT 5 -- ds50010--------
rs1832705721,2
--153601465(+) GTTCAC/TGCCAT 5 -- ds50010--------
rs1868862541,2
--153601518(+) CGCCAC/GCACGC 5 -- ds50010--------
rs1384970721,2
--153601520(+) CCACCA/GCGCCC 5 -- ds50010--------

HapMap Linkage Disequilibrium report for FAM3A (153733323 - 153744566 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for FAM3A:    About this table    
Variant IDTypeSubtypePubMed ID
nsv508816CNV Insertion20534489
nsv519042CNV Gain19592680
esv33199CNV Gain+Loss17666407
esv33784CNV Gain+Loss17666407

Locus Specific Mutation Databases (LSDB): FAM3A

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing FAM3A
DNA2.0 Custom Variant and Variant Library Synthesis for FAM3A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 300492    OMIM disorders: --

1 disease from the University of Copenhagen DISEASES database for FAM3A:
Nonsyndromic deafness

Find genes that share disorders with FAM3A           About GenesLikeMe


Export disorders for FAM3A gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for FAM3A gene, integrated from 10 sources (see all 18):
(articles sorted by number of sources associating them with FAM3A)
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  1. Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci. (PubMed id 8733135)1, 2, 3 Chen E.Y....D'Urso M. (Hum. Mol. Genet. 1996)
  2. Cloning, expression, and initial characterization of a novel cytokine-like gene family. (PubMed id 12160727)1, 2, 9 Zhu Y.... Young P.R. (Genomics 2002)
  3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Transcriptional organization of a 450-kb region of the human X chromosome in Xq28. (PubMed id 8248200)1, 2 Bione S.... Toniolo D. (Proc. Natl. Acad. Sci. U.S.A. 1993)
  6. Construction of a transcription map of a 300 kb region around the human G6PD locus by direct cDNA selection. (PubMed id 8281148)1, 3 Sedlacek Z....Poustka A. (Hum. Mol. Genet. 1993)
  7. GG: a domain involved in phage LTF apparatus and implicated in human MEB and non-syndromic hearing loss diseases. (PubMed id 16406369)1, 9 Guo J....Yu L. (FEBS Lett. 2006)
  8. Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network. (PubMed id 23446634)1 Chen Z....Reiner A.P. (Hum. Mol. Genet. 2013)
  9. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  10. FAM3A is a target gene of peroxisome proliferator-activated receptor gamma. (PubMed id 23562554)1 Zhou Y....Yang J. (Biochim. Biophys. Acta 2013)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 60343 HGNC: 13749 AceView: FAM3A Ensembl:ENSG00000071889 euGenes: HUgn60343
ECgene: FAM3A H-InvDB: FAM3A

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for FAM3A Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for FAM3A gene:
Search GeneIP for patents involving FAM3A

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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