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Aliases for FAM32A Gene

Aliases for FAM32A Gene

  • Family With Sequence Similarity 32, Member A 2 3
  • OTAG12 3 4 6
  • Ovarian Tumor-Associated Gene 12 3 4
  • OTAG-12 3 4
  • Ovarian Tumor Associated Gene-12 3
  • Protein FAM32A 3

External Ids for FAM32A Gene

Previous GeneCards Identifiers for FAM32A Gene

  • GC19P016157
  • GC19P016297
  • GC19P015867
  • GC19P016301
  • GC19P016431
  • GC19P017106
  • GC19P017362
  • GC19P017894

Summaries for FAM32A Gene

GeneCards Summary for FAM32A Gene

FAM32A (Family With Sequence Similarity 32, Member A) is a Protein Coding gene.

UniProtKB/Swiss-Prot for FAM32A Gene

  • Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli.

Gene Wiki entry for FAM32A Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM32A Gene

Genomics for FAM32A Gene

Regulatory Elements for FAM32A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM32A Gene

Start:
16,185,380 bp from pter
End:
16,192,046 bp from pter
Size:
6,667 bases
Orientation:
Plus strand

Genomic View for FAM32A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM32A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM32A Gene

Proteins for FAM32A Gene

  • Protein details for FAM32A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9Y421-FA32A_HUMAN
    Recommended name:
    Protein FAM32A
    Protein Accession:
    Q9Y421
    Secondary Accessions:
    • Q9BT02

    Protein attributes for FAM32A Gene

    Size:
    112 amino acids
    Molecular mass:
    13178 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM32A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM32A Gene

Proteomics data for FAM32A Gene at MOPED

Post-translational modifications for FAM32A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM32A Gene

No data available for DME Specific Peptides for FAM32A Gene

Domains for FAM32A Gene

Protein Domains for FAM32A Gene

Suggested Antigen Peptide Sequences for FAM32A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9Y421

UniProtKB/Swiss-Prot:

FA32A_HUMAN :
  • Q9Y421
Family:
  • Belongs to the FAM32 family.
genes like me logo Genes that share domains with FAM32A: view

No data available for Gene Families for FAM32A Gene

Function for FAM32A Gene

Molecular function for FAM32A Gene

UniProtKB/Swiss-Prot Function: Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli.
UniProtKB/Swiss-Prot Induction: By etoposide, puromycin or carboplatin.

Gene Ontology (GO) - Molecular Function for FAM32A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 22365833
GO:0044822 poly(A) RNA binding IDA 22658674
genes like me logo Genes that share ontologies with FAM32A: view

Animal Model Products

CRISPR Products

miRNA for FAM32A Gene

miRTarBase miRNAs that target FAM32A

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM32A

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM32A Gene

Localization for FAM32A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM32A Gene

Isoform 1: Nucleus.
Isoform 2: Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM32A Gene COMPARTMENTS Subcellular localization image for FAM32A gene
Compartment Confidence
nucleus 5
cytosol 1
extracellular 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FAM32A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
GO:0005654 nucleoplasm IDA --
GO:0005730 nucleolus IDA --
GO:0005739 mitochondrion IDA --
GO:0043231 intracellular membrane-bounded organelle IDA --
genes like me logo Genes that share ontologies with FAM32A: view

Pathways for FAM32A Gene

SuperPathways for FAM32A Gene

No Data Available

Interacting Proteins for FAM32A Gene

Gene Ontology (GO) - Biological Process for FAM32A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006915 apoptotic process IEA --
GO:0007049 cell cycle IEA --
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with FAM32A: view

No data available for Pathways by source for FAM32A Gene

Transcripts for FAM32A Gene

Unigene Clusters for FAM32A Gene

Family with sequence similarity 32, member A:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM32A

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM32A Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d
SP1:
SP2: -
SP3: -
SP4: - -

Relevant External Links for FAM32A Gene

GeneLoc Exon Structure for
FAM32A
ECgene alternative splicing isoforms for
FAM32A

Expression for FAM32A Gene

mRNA expression in normal human tissues for FAM32A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM32A Gene

SOURCE GeneReport for Unigene cluster for FAM32A Gene Hs.631614

mRNA Expression by UniProt/SwissProt for FAM32A Gene

Q9Y421-FA32A_HUMAN
Tissue specificity: Expressed in ovary, with isoform 1 being predominant.
genes like me logo Genes that share expressions with FAM32A: view

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for FAM32A Gene

Orthologs for FAM32A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM32A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM32A 35
  • 99.7 (n)
  • 100 (a)
FAM32A 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM32A 35
  • 93.75 (n)
  • 100 (a)
FAM32A 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM32A 35
  • 93.45 (n)
  • 99.11 (a)
FAM32A 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam32a 35
  • 88.69 (n)
  • 97.32 (a)
Fam32a 16
Fam32a 36
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM32A 36
  • 85 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM32A 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam32a 35
  • 89.58 (n)
  • 98.21 (a)
chicken
(Gallus gallus)
Aves FAM32A 35
  • 78.68 (n)
  • 78.38 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.13214 35
tropical clawed frog
(Silurana tropicalis)
Amphibia fam32a 35
  • 68.47 (n)
  • 74.77 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.9554 35
zebrafish
(Danio rerio)
Actinopterygii fam32a 35
  • 66.97 (n)
  • 70.64 (a)
fam32al 36
  • 71 (a)
OneToOne
wufc30d06 35
fruit fly
(Drosophila melanogaster)
Insecta CG15432 36
  • 46 (a)
OneToOne
Species with no ortholog for FAM32A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM32A Gene

ENSEMBL:
Gene Tree for FAM32A (if available)
TreeFam:
Gene Tree for FAM32A (if available)

Paralogs for FAM32A Gene

genes like me logo Genes that share paralogs with FAM32A: view

No data available for Paralogs for FAM32A Gene

Variants for FAM32A Gene

Sequence variations from dbSNP and Humsavar for FAM32A Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs206231 -- 16,190,501(-) AGACA(C/T)GGAGG intron-variant
rs285233 -- 16,189,488(-) AACTC(A/G)AAGGA intron-variant
rs285234 -- 16,189,379(-) GAAAG(A/G)AAGGA intron-variant
rs285235 -- 16,189,141(-) GGAGG(C/G)TGAGG intron-variant
rs285236 -- 16,188,363(-) cctgc(A/G)atcct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM32A Gene

Variant ID Type Subtype PubMed ID
nsv833767 CNV Loss 17160897

Relevant External Links for FAM32A Gene

HapMap Linkage Disequilibrium report
FAM32A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM32A Gene

Disorders for FAM32A Gene

Relevant External Links for FAM32A

Genetic Association Database (GAD)
FAM32A
Human Genome Epidemiology (HuGE) Navigator
FAM32A
genes like me logo Genes that share disorders with FAM32A: view

No data available for UniProtKB/Swiss-Prot for FAM32A Gene

Publications for FAM32A Gene

  1. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3 4
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 48
  5. Anti-proliferative and pro-apoptotic actions of a novel human and mouse ovarian tumor-associated gene OTAG-12: downregulation, alternative splicing and drug sensitization. (PMID: 21339736) Chen X. … Sairam M.R. (Oncogene 2011) 3 4

Products for FAM32A Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate FAM32A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for FAM32A
    • Block miRNA regulation of FAM32A using miScript Target Protectors

    Sources for FAM32A Gene

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