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Aliases for FAM27E2 Gene

Subcategory (RNA class) for FAM27E2 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for FAM27E2 Gene

  • Family With Sequence Similarity 27 Member E2 2 3 5
  • Family With Sequence Similarity 27, Member E1 2 3
  • Family With Sequence Similarity 27, Member E2 2
  • FAM27E1 3

External Ids for FAM27E2 Gene

Previous HGNC Symbols for FAM27E2 Gene

  • FAM27E1

Previous GeneCards Identifiers for FAM27E2 Gene

  • GC09P045623
  • GC09U901197
  • GC00U924109
  • GC09P045734

Summaries for FAM27E2 Gene

GeneCards Summary for FAM27E2 Gene

FAM27E2 (Family With Sequence Similarity 27 Member E2) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM27E2 Gene

Genomics for FAM27E2 Gene

Regulatory Elements for FAM27E2 Gene

Enhancers for FAM27E2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F041646 0.2 Ensembl 0.8 -1.1 -1074 0.4 ENSG00000278077 FAM27E2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM27E2 on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM27E2 Gene

Chromosome:
9
Start:
41,647,674 bp from pter
End:
41,649,440 bp from pter
Size:
1,767 bases
Orientation:
Plus strand

Genomic View for FAM27E2 Gene

Genes around FAM27E2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM27E2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM27E2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM27E2 Gene

Proteins for FAM27E2 Gene

Post-translational modifications for FAM27E2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FAM27E2 Gene

Domains & Families for FAM27E2 Gene

Suggested Antigen Peptide Sequences for FAM27E2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for FAM27E2 Gene

Function for FAM27E2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM27E2 Gene

Localization for FAM27E2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM27E2 gene
Compartment Confidence
nucleus 3
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM27E2 Gene

Pathways & Interactions for FAM27E2 Gene

SuperPathways for FAM27E2 Gene

No Data Available

Interacting Proteins for FAM27E2 Gene

Gene Ontology (GO) - Biological Process for FAM27E2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM27E2 Gene

Transcripts for FAM27E2 Gene

mRNA/cDNA for FAM27E2 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM27E2 Gene

Family with sequence similarity 27, member E2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM27E2 Gene

No ASD Table

Relevant External Links for FAM27E2 Gene

GeneLoc Exon Structure for
FAM27E2
ECgene alternative splicing isoforms for
FAM27E2

Expression for FAM27E2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FAM27E2 Gene

mRNA differential expression in normal tissues according to GTEx for FAM27E2 Gene

This gene is overexpressed in Pituitary (x4.9).

NURSA nuclear receptor signaling pathways regulating expression of FAM27E2 Gene:

FAM27E2

SOURCE GeneReport for Unigene cluster for FAM27E2 Gene:

Hs.651656
genes like me logo Genes that share expression patterns with FAM27E2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for FAM27E2 Gene

Orthologs for FAM27E2 Gene

Evolution for FAM27E2 Gene

ENSEMBL:
Gene Tree for FAM27E2 (if available)
TreeFam:
Gene Tree for FAM27E2 (if available)

No data available for Orthologs for FAM27E2 Gene

Paralogs for FAM27E2 Gene

(3) SIMAP similar genes for FAM27E2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM27E2: view

No data available for Paralogs for FAM27E2 Gene

Variants for FAM27E2 Gene

Sequence variations from dbSNP and Humsavar for FAM27E2 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs111325043 -- 41,647,111(+) AAATC(A/G)AAGAA upstream-variant-2KB
rs111355957 -- 41,646,223(+) CGACT(C/G)CTGGC upstream-variant-2KB
rs111641812 -- 41,647,762(+) TATCA(C/T)CGTTC nc-transcript-variant
rs111706661 -- 41,648,788(+) GTGAC(C/G)GGAGA nc-transcript-variant
rs111865316 -- 41,646,144(+) TCCGG(G/T)CAGGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM27E2 Gene

Variant ID Type Subtype PubMed ID
esv1008671 CNV gain 20482838
esv3351354 CNV duplication 20981092
esv3357996 CNV duplication 20981092
esv3891676 CNV gain 25118596
esv989841 CNV gain 20482838
nsv1076161 CNV deletion 25765185
nsv1076163 CNV deletion 25765185
nsv1119301 CNV duplication 24896259
nsv1145231 CNV deletion 24896259
nsv469519 CNV gain+loss 16826518
nsv469535 CNV gain 16826518
nsv469761 CNV gain 16826518
nsv471659 CNV gain+loss 15918152
nsv614501 CNV loss 21841781
nsv614531 CNV gain 21841781
nsv831591 CNV loss 17160897
nsv8477 CNV gain+loss 18304495
nsv951160 CNV deletion 24416366
nsv951476 CNV deletion 24416366
nsv972724 CNV duplication 23825009
nsv972726 CNV duplication 23825009
nsv972744 CNV duplication 23825009
nsv982263 CNV duplication 23825009

Variation tolerance for FAM27E2 Gene

Gene Damage Index Score: 4.89; 67.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM27E2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM27E2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM27E2 Gene

Disorders for FAM27E2 Gene

Relevant External Links for FAM27E2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM27E2

No disorders were found for FAM27E2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM27E2 Gene

Publications for FAM27E2 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for FAM27E2 Gene

Sources for FAM27E2 Gene

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