FAM27E2 Gene
protein-coding GIFtS: 23
GCID: GC09P045734
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family with sequence similarity 27, member E2
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Aliases
for FAM27E2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
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| Aliases |
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| Family With Sequence Similarity 27, Member E21 2 |
Export aliases for FAM27E2 gene to outside databasesPrevious GC identifers: GC09P045623 GC09U901197 GC00U924109 |
Summaries
for FAM27E2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
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Genomic Views
for FAM27E2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NT_078053.4 NC_018920.1
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for FAM27E2
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM27E2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM27E2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9p11.2 Ensembl cytogenetic band: 9p11.2 HGNC cytogenetic band: 9p11.2FAM27E2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P045734: view genomic region
(about GC identifiers)
Start:
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45,733,559 bp from pter |
End:
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45,734,896 bp from pter |
Size:
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1,338 bases |
Orientation:
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plus strand |
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Proteins
for FAM27E2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
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UniProtKB/Swiss-Prot: F27E2_HUMAN, Q5SNX5 (See
protein sequence)Recommended Name: Protein FAM27E2 Size: 125 amino acids; 14711 Da
Secondary accessions: A8E4L5Explore the universe of human proteins at neXtProt for FAM27E2: NX_Q5SNX5
FAM27E2 Protein expression data from MOPED and PaxDb: About this image 
ENSEMBL proteins: ENSP00000366752
Human Recombinant Protein Products:
FAM27E2 Antibody Products:
Assay Products for FAM27E2: |
Protein
Domains /
Families
for FAM27E2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5SNX5 UniProtKB/Swiss-Prot: F27E2_HUMAN, Q5SNX5Similarity: Belongs to the FAM27 family |
Function
for FAM27E2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
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Pathways & Interactions
for FAM27E2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM27E2
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Drugs & Compounds
for FAM27E2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for FAM27E2
Search CenterWatch for drugs/clinical trials and news about FAM27E2 / F27E2 
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Transcripts
for FAM27E2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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Unigene Cluster for FAM27E2: Family with sequence similarity 27, member E2 Hs.651656 [show with all ESTs]Unigene Representative Sequence: BC1482611 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000377529
Additional cDNA sequence: BC148261.1 2 DOTS entries: DT.102842423 DT.212740
GeneLoc Exon Structure
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Expression
for FAM27E2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM27E2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See FAM27E2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM27E2
SOURCE GeneReport for Unigene cluster: Hs.651656
SABiosciences Custom PCR Arrays for FAM27E2
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat FAM27E2 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM27E2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM27E2 |
Orthologs
for FAM27E2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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ENSEMBL Gene Tree for FAM27E2 (if available)
TreeFam Gene Tree for FAM27E2 (if available) |
Paralogs
for FAM27E2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM27E2 gene
- LOC1005096382 FAM27E32
3 SIMAP similar genes for FAM27E2 using alignment to 1 protein entry: F27E2_HUMAN:FAM27E1 FAM27E3 FAM27D1
FAM27E2 for paralogs About GeneDecksing
5/24 Pseudogenes.org Pseudogenes for FAM27E2 (see all 24)
PGOHUM00000239407 PGOHUM00000239408 PGOHUM00000248851 PGOHUM00000249095 PGOHUM00000258039
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Genomic Variants
for FAM27E2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for FAM27E2 (45733559 - 45734896 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM27E2: -- | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for FAM27E2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
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Publications
for FAM27E2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
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PubMed articles for FAM27E2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM27E2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM27E2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing FAM27E2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing FAM27E2 gene
(According to HUGE)
About This Section
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Specialized Databases showing FAM27E2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for FAM27E2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for FAM27E2 gene:
Search GeneIP for patents involving FAM27E2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for FAM27E2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM27E2 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM27E2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM27E2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM27E2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM27E2 | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM27E2 |
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| | | | Search Tocris compounds for FAM27E2 |
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 | | | | |  |  |  | | | | Search ThermoFisher Antibodies for FAM27E2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FAM27E2 |
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