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Aliases for FAM26F Gene

Aliases for FAM26F Gene

  • Family With Sequence Similarity 26 Member F 2 3 5
  • Family With Sequence Similarity 26, Member F 2 3
  • C6orf187 3 4
  • Chromosome 6 Open Reading Frame 187 2
  • DJ93H18.5 3

External Ids for FAM26F Gene

Previous HGNC Symbols for FAM26F Gene

  • C6orf187

Previous GeneCards Identifiers for FAM26F Gene

  • GC06P116891
  • GC06P116782
  • GC06P114362

Summaries for FAM26F Gene

GeneCards Summary for FAM26F Gene

FAM26F (Family With Sequence Similarity 26 Member F) is a Protein Coding gene. GO annotations related to this gene include cation channel activity. An important paralog of this gene is CALHM2.

UniProtKB/Swiss-Prot for FAM26F Gene

  • Pore-forming subunit of a voltage-gated ion channel.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM26F Gene

Genomics for FAM26F Gene

Regulatory Elements for FAM26F Gene

Enhancers for FAM26F Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM26F on UCSC Golden Path with GeneCards custom track

Promoters for FAM26F Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM26F on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM26F Gene

116,461,370 bp from pter
116,463,782 bp from pter
2,413 bases
Plus strand

Genomic View for FAM26F Gene

Genes around FAM26F on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM26F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM26F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM26F Gene

Proteins for FAM26F Gene

  • Protein details for FAM26F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM26F
    Protein Accession:
    Secondary Accessions:
    • B9EJB0
    • Q5R3K4

    Protein attributes for FAM26F Gene

    315 amino acids
    Molecular mass:
    34458 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM26F Gene


neXtProt entry for FAM26F Gene

Proteomics data for FAM26F Gene at MOPED

Post-translational modifications for FAM26F Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM26F Gene

No data available for DME Specific Peptides for FAM26F Gene

Domains & Families for FAM26F Gene

Protein Domains for FAM26F Gene


Suggested Antigen Peptide Sequences for FAM26F Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM26 family.
  • Belongs to the FAM26 family.
genes like me logo Genes that share domains with FAM26F: view

No data available for Gene Families for FAM26F Gene

Function for FAM26F Gene

Molecular function for FAM26F Gene

UniProtKB/Swiss-Prot Function:
Pore-forming subunit of a voltage-gated ion channel.
genes like me logo Genes that share phenotypes with FAM26F: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM26F Gene

Localization for FAM26F Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM26F Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for FAM26F Gene COMPARTMENTS Subcellular localization image for FAM26F gene
Compartment Confidence
plasma membrane 5
nucleus 2

No data available for Gene Ontology (GO) - Cellular Components for FAM26F Gene

Pathways & Interactions for FAM26F Gene

SuperPathways for FAM26F Gene

No Data Available

Interacting Proteins for FAM26F Gene

Gene Ontology (GO) - Biological Process for FAM26F Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM26F Gene

Drugs & Compounds for FAM26F Gene

No Compound Related Data Available

Transcripts for FAM26F Gene

Unigene Clusters for FAM26F Gene

Family with sequence similarity 26, member F:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM26F Gene

No ASD Table

Relevant External Links for FAM26F Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM26F Gene

mRNA expression in normal human tissues for FAM26F Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM26F Gene

This gene is overexpressed in Spleen (x19.5) and Whole Blood (x4.4).

Protein differential expression in normal tissues from HIPED for FAM26F Gene

This gene is overexpressed in Ovary (49.2) and Skin (8.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM26F Gene

SOURCE GeneReport for Unigene cluster for FAM26F Gene Hs.381220

genes like me logo Genes that share expression patterns with FAM26F: view

Protein tissue co-expression partners for FAM26F Gene

Primer Products

No data available for mRNA Expression by UniProt/SwissProt for FAM26F Gene

Orthologs for FAM26F Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM26F Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM26F 35
  • 85.36 (n)
  • 78.53 (a)
FAM26F 36
  • 77 (a)
(Canis familiaris)
Mammalia FAM26F 35
  • 85.38 (n)
  • 79.68 (a)
FAM26F 36
  • 77 (a)
(Mus musculus)
Mammalia Fam26f 35
  • 77.14 (n)
  • 69.87 (a)
Fam26f 16
Fam26f 36
  • 69 (a)
(Pan troglodytes)
Mammalia FAM26F 35
  • 99.47 (n)
  • 98.41 (a)
FAM26F 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Fam26f 35
  • 77.38 (n)
  • 70.74 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 59 (a)
-- 36
  • 42 (a)
(Gallus gallus)
Aves FAM26F 35
  • 59.41 (n)
  • 51.16 (a)
FAM26F 36
  • 45 (a)
(Anolis carolinensis)
Reptilia FAM26F 36
  • 51 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731134 35
  • 58.88 (n)
  • 51.09 (a)
(Danio rerio)
Actinopterygii fam26f 35
  • 51.08 (n)
  • 41.23 (a)
fam26f 36
  • 39 (a)
(Caenorhabditis elegans)
Secernentea clhm-1 36
  • 20 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 16 (a)
Species with no ortholog for FAM26F:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM26F Gene

Gene Tree for FAM26F (if available)
Gene Tree for FAM26F (if available)

Paralogs for FAM26F Gene

Paralogs for FAM26F Gene

(3) SIMAP similar genes for FAM26F Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM26F: view

Variants for FAM26F Gene

Sequence variations from dbSNP and Humsavar for FAM26F Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1057192 - 116,462,167(+) TCACC(A/G)GATGC intron-variant, reference, missense
rs11544160 - 116,463,634(+) CTACT(A/G)AAGGA reference, missense
rs10784 - 116,462,227(-) TTGCG(C/T)GCACA intron-variant, reference, missense
rs9488937 -- 116,460,228(+) TGACC(A/G)TGAAG upstream-variant-2KB
rs10452638 -- 116,460,362(+) TTAAG(A/C)AGGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM26F Gene

Variant ID Type Subtype PubMed ID
nsv523972 CNV Gain 19592680
nsv830783 CNV Gain 17160897

Variation tolerance for FAM26F Gene

Gene Damage Index Score: 9.46; 88.68% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM26F Gene

Disorders for FAM26F Gene

Relevant External Links for FAM26F

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM26F Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM26F Gene

Publications for FAM26F Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 67
  2. A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis. (PMID: 25082827) JuliA A. … Marsal S. (Hum. Mol. Genet. 2014) 3
  3. CBFI^ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. (PMID: 23333304) Kim D.Y. … Gross J.D. (Mol. Cell 2013) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for FAM26F Gene

Sources for FAM26F Gene