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Aliases for FAM26F Gene

Aliases for FAM26F Gene

  • Family With Sequence Similarity 26, Member F 2 3
  • C6orf187 3 4
  • Chromosome 6 Open Reading Frame 187 2
  • Protein FAM26F 3
  • DJ93H18.5 3

External Ids for FAM26F Gene

Previous Symbols for FAM26F Gene

  • C6orf187

Summaries for FAM26F Gene

GeneCards Summary for FAM26F Gene

FAM26F (Family With Sequence Similarity 26, Member F) is a Protein Coding gene. An important paralog of this gene is CALHM2.

UniProtKB/Swiss-Prot for FAM26F Gene

  • Pore-forming subunit of a voltage-gated ion channel.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM26F Gene

Genomics for FAM26F Gene

Genomic Location for FAM26F Gene

Start:
116,461,370 bp from pter
End:
116,463,785 bp from pter
Size:
2,416 bases
Orientation:
Plus strand

Genomic View for FAM26F Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM26F Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM26F Gene

Regulatory Elements for FAM26F Gene

Proteins for FAM26F Gene

  • Protein details for FAM26F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5R3K3-FA26F_HUMAN
    Recommended name:
    Protein FAM26F
    Protein Accession:
    Q5R3K3
    Secondary Accessions:
    • B9EJB0
    • Q5R3K4

    Protein attributes for FAM26F Gene

    Size:
    315 amino acids
    Molecular mass:
    34458 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM26F Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM26F Gene

Proteomics data for FAM26F Gene at MOPED

Post-translational modifications for FAM26F Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM26F Gene

No data available for DME Specific Peptides for FAM26F Gene

Domains for FAM26F Gene

Protein Domains for FAM26F Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

FA26F_HUMAN
Family:
  • Belongs to the FAM26 family.:
    • Q5R3K3
genes like me logo Genes that share domains with FAM26F: view

No data available for Gene Families for FAM26F Gene

Function for FAM26F Gene

Molecular function for FAM26F Gene

UniProtKB/Swiss-Prot Function: Pore-forming subunit of a voltage-gated ion channel.

Gene Ontology (GO) - Molecular Function for FAM26F Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005261 cation channel activity IBA --
genes like me logo Genes that share ontologies with FAM26F: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for FAM26F Gene

Localization for FAM26F Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM26F Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM26F Gene COMPARTMENTS Subcellular localization image for FAM26F gene
Compartment Confidence
plasma membrane 3
nucleus 1

Gene Ontology (GO) - Cellular Components for FAM26F Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with FAM26F: view

Pathways for FAM26F Gene

SuperPathways for FAM26F Gene

No Data Available

Interacting Proteins for FAM26F Gene

Gene Ontology (GO) - Biological Process for FAM26F Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006811 ion transport --
GO:0006812 cation transport IBA --
GO:0034220 ion transmembrane transport IBA --
GO:0098655 cation transmembrane transport IBA --
genes like me logo Genes that share ontologies with FAM26F: view

No data available for Pathways by source for FAM26F Gene

Transcripts for FAM26F Gene

mRNA/cDNA for FAM26F Gene

Unigene Clusters for FAM26F Gene

Family with sequence similarity 26, member F:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM26F Gene

No ASD Table

Relevant External Links for FAM26F Gene

GeneLoc Exon Structure for
FAM26F
ECgene alternative splicing isoforms for
FAM26F

Expression for FAM26F Gene

mRNA expression in normal human tissues for FAM26F Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM26F Gene

This gene is overexpressed in Spleen (19.5) and Whole Blood (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM26F Gene

SOURCE GeneReport for Unigene cluster for FAM26F Gene Hs.381220

genes like me logo Genes that share expressions with FAM26F: view

Orthologs for FAM26F Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM26F Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM26F 36
  • 99.47 (n)
  • 98.41 (a)
FAM26F 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM26F 36
  • 85.36 (n)
  • 78.53 (a)
FAM26F 37
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM26F 36
  • 85.38 (n)
  • 79.68 (a)
FAM26F 37
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam26f 36
  • 77.14 (n)
  • 69.87 (a)
Fam26f 16
Fam26f 37
  • 69 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 59 (a)
OneToMany
-- 37
  • 42 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam26f 36
  • 77.38 (n)
  • 70.74 (a)
chicken
(Gallus gallus)
Aves FAM26F 36
  • 59.41 (n)
  • 51.16 (a)
FAM26F 37
  • 45 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM26F 37
  • 51 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731134 36
  • 58.88 (n)
  • 51.09 (a)
zebrafish
(Danio rerio)
Actinopterygii fam26f 36
  • 51.08 (n)
  • 41.23 (a)
fam26f 37
  • 39 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea clhm-1 37
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 16 (a)
OneToMany
Species with no ortholog for FAM26F:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM26F Gene

ENSEMBL:
Gene Tree for FAM26F (if available)
TreeFam:
Gene Tree for FAM26F (if available)

Paralogs for FAM26F Gene

Paralogs for FAM26F Gene

Selected SIMAP similar genes for FAM26F Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with FAM26F: view

Variants for FAM26F Gene

Sequence variations from dbSNP and Humsavar for FAM26F Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs10784 -- 116,462,227(-) TTGCG(C/T)GCACA reference, missense, intron-variant
rs508250 -- 116,463,101(+) CAAAC(A/G)AGAAG intron-variant
rs743853 -- 116,462,596(+) TCTAA(C/T)TTGCC intron-variant
rs1057192 - 116,462,167(+) TCACC(A/G)GATGC missense, reference, intron-variant
rs2016676 -- 116,462,835(-) TCACT(A/C)TATAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM26F Gene

Variant ID Type Subtype PubMed ID
nsv523972 CNV Gain 19592680
nsv830783 CNV Gain 17160897

Relevant External Links for FAM26F Gene

HapMap Linkage Disequilibrium report
FAM26F

Disorders for FAM26F Gene

No disorders were found for FAM26F Gene.

No data available for UniProtKB/Swiss-Prot for FAM26F Gene

Publications for FAM26F Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. CBFI^ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression. (PMID: 23333304) Kim D.Y. … Gross J.D. (Mol. Cell 2013) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for FAM26F Gene

  • antibodies-online peptides for FAM26F
  • antibodies-online antibodies for FAM26F
  • antibodies-online kits for FAM26F

Sources for FAM26F Gene

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